NO993731D0 - Pyrrolopyrazolopyrimidin-forbindelse og medisin omfattende denne - Google Patents

Pyrrolopyrazolopyrimidin-forbindelse og medisin omfattende denne

Info

Publication number
NO993731D0
NO993731D0 NO993731A NO993731A NO993731D0 NO 993731 D0 NO993731 D0 NO 993731D0 NO 993731 A NO993731 A NO 993731A NO 993731 A NO993731 A NO 993731A NO 993731 D0 NO993731 D0 NO 993731D0
Authority
NO
Norway
Prior art keywords
medicine
pyrrolopyrazolopyrimidine
compound
pyrrolopyrazolopyrimidine compound
Prior art date
Application number
NO993731A
Other languages
English (en)
Other versions
NO993731L (no
NO314404B1 (no
Inventor
Takayuki Namiki
Masayuki Yuasa
Takako Takakuwa
Satoshi Ichinomiya
Yukio Kawazu
Kenichi Kishii
Norio Funayama
Mariko Harada
Kyoko Taneda
Naoki Hiyama
Tomoaki Yahiro
Mayumi Sugio
Masashi Tamai
Original Assignee
Pola Chem Ind Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pola Chem Ind Inc filed Critical Pola Chem Ind Inc
Publication of NO993731D0 publication Critical patent/NO993731D0/no
Publication of NO993731L publication Critical patent/NO993731L/no
Publication of NO314404B1 publication Critical patent/NO314404B1/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains three hetero rings
    • C07D487/14—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pulmonology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
NO19993731A 1997-02-03 1999-08-02 Pyrrolopyrazolopyrimidin-forbindelser og medisin omfattende denne og fremgangsmåte for fremstilling derav NO314404B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP9020387A JPH10218881A (ja) 1997-02-03 1997-02-03 新規なピロロピラゾロピリミジン誘導体
PCT/JP1998/000315 WO1998033799A1 (en) 1997-02-03 1998-01-27 Pyrrolopyrazolopyrimidine compound and medicine comprising the same

Publications (3)

Publication Number Publication Date
NO993731D0 true NO993731D0 (no) 1999-08-02
NO993731L NO993731L (no) 1999-09-22
NO314404B1 NO314404B1 (no) 2003-03-17

Family

ID=12025624

Family Applications (1)

Application Number Title Priority Date Filing Date
NO19993731A NO314404B1 (no) 1997-02-03 1999-08-02 Pyrrolopyrazolopyrimidin-forbindelser og medisin omfattende denne og fremgangsmåte for fremstilling derav

Country Status (7)

Country Link
US (2) US5942515A (no)
EP (1) EP1021447A1 (no)
JP (1) JPH10218881A (no)
AU (1) AU725356B2 (no)
CA (1) CA2228360A1 (no)
NO (1) NO314404B1 (no)
WO (1) WO1998033799A1 (no)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6329382B1 (en) 1997-02-14 2001-12-11 Pola Chemical Industries, Inc. Pyrrolo[3,2-e]pyrazolo[1,5-a]pyrimidine remedies/preventives for respiratory diseases
EP0976754B1 (en) * 1997-02-14 2004-07-14 Pola Chemical Industries, Inc. Remedies/preventives for respiratory diseases
TWI271406B (en) 1999-12-13 2007-01-21 Eisai Co Ltd Tricyclic condensed heterocyclic compounds, preparation method of the same and pharmaceuticals comprising the same
DE10012861C2 (de) * 2000-03-16 2002-07-11 Gsf Forschungszentrum Umwelt Rekombinante HHV8-DNA
US7425559B2 (en) 2001-07-13 2008-09-16 Btg International Limited Medicine containing pyrimidine derivative
WO2004075846A2 (en) 2003-02-25 2004-09-10 Bristol-Myers Squibb Company Pyrazolopurine-based tricyclic compounds and pharmaceutical compositions comprising same
WO2006087325A1 (de) * 2005-02-16 2006-08-24 Basf Aktiengesellschaft 5-alkoxyalkyl-6-alkyl-7-amino-azolopyrimidine, verfahren zu ihrer herstellung und ihre verwendung zur bekämpfung von schadpilzen sowie sie enthaltende mittel
US8431603B2 (en) 2008-04-15 2013-04-30 Eisai R&D Management Co., Ltd. 3-phenylpyrazolo[5,1-b]thiazole compounds
WO2012024495A1 (en) * 2010-08-18 2012-02-23 Massachusetts Institute Of Technology Use of azides in synthesis
WO2012027239A1 (en) * 2010-08-23 2012-03-01 Schering Corporation NOVEL PYRAZOLO[1,5-a]PYRROLO[3,2-e]PYRIMIDINE DERIVATIVES AS mTOR INHIBITORS
EP2723746A1 (en) 2011-06-22 2014-04-30 Vertex Pharmaceuticals Inc. Compounds useful as inhibitors of atr kinase
CN104903325B (zh) 2012-12-07 2017-10-20 沃泰克斯药物股份有限公司 可用作atr激酶抑制剂的化合物
WO2014143242A1 (en) 2013-03-15 2014-09-18 Vertex Pharmaceuticals Incorporated Compounds useful as inhibitors of atr kinase
WO2014143240A1 (en) 2013-03-15 2014-09-18 Vertex Pharmaceuticals Incorporated Fused pyrazolopyrimidine derivatives useful as inhibitors of atr kinase
JP2016512239A (ja) 2013-03-15 2016-04-25 バーテックス ファーマシューティカルズ インコーポレイテッドＶｅｒｔｅｘ Ｐｈａｒｍａｃｅｕｔｉｃａｌｓ Ｉｎｃｏｒｐｏｒａｔｅｄ Ａｔｒキナーゼの阻害剤として有用な化合物
CN105934435B (zh) 2013-12-06 2019-02-22 沃泰克斯药物股份有限公司 用作atr激酶抑制剂的化合物，其制备，及其放射性标记的衍生物
KR102575125B1 (ko) 2014-06-05 2023-09-07 버텍스 파마슈티칼스 인코포레이티드 Atr 키나제의 저해제로서 유용한 2-아미노-6-플루오로-n-[5-플루오로-피리딘-3-일]-피라졸로[1,5-a]피리미딘-3-카복스아미드 화합물의 방사성표지된 유도체, 상기 화합물의 제조 및 이의 다양한 고체 형태
PL3157566T3 (pl) 2014-06-17 2019-10-31 Vertex Pharma Metoda leczenia nowotworu przy użyciu kombinacji inhibitorów chk1 i atr
EP3355926A4 (en) 2015-09-30 2019-08-21 Vertex Pharmaceuticals Inc. METHOD FOR THE TREATMENT OF CANCER WITH A COMBINATION OF DNA DAMAGING AGENTS AND ATR INHIBITORS

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0276880A (ja) * 1988-06-16 1990-03-16 Sankyo Co Ltd 悪液質改善治療剤
CA1330079C (en) * 1988-10-13 1994-06-07 Michihiko Tsujitani Pyrrolo (3,2-e)pyrazolo(1,5-a)pyrimidine derivative and medicine comprising the same
DK69592A (da) * 1992-05-26 1993-11-27 Eskofot As Apparat til eksponering og fremkaldelse af lysfoelsomt materiale, fortrinsvis offsetplader

Also Published As

Publication number Publication date
EP1021447A1 (en) 2000-07-26
AU725356B2 (en) 2000-10-12
NO993731L (no) 1999-09-22
NO314404B1 (no) 2003-03-17
JPH10218881A (ja) 1998-08-18
CA2228360A1 (en) 1998-08-03
US5942515A (en) 1999-08-24
AU5577798A (en) 1998-08-25
US6057330A (en) 2000-05-02
WO1998033799A1 (en) 1998-08-06

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