NO20073465L - Benzotiazol-derivater - Google Patents
Benzotiazol-derivaterInfo
- Publication number
- NO20073465L NO20073465L NO20073465A NO20073465A NO20073465L NO 20073465 L NO20073465 L NO 20073465L NO 20073465 A NO20073465 A NO 20073465A NO 20073465 A NO20073465 A NO 20073465A NO 20073465 L NO20073465 L NO 20073465L
- Authority
- NO
- Norway
- Prior art keywords
- benzothiazole derivatives
- compounds
- treatment
- pharmaceutically acceptable
- general formula
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A61K31/427—Thiazoles not condensed and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A61K31/428—Thiazoles condensed with carbocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/444—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring heteroatom, e.g. amrinone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/455—Nicotinic acids, e.g. niacin; Derivatives thereof, e.g. esters, amides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A61K31/5375—1,4-Oxazines, e.g. morpholine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
- A61K31/541—Non-condensed thiazines containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
- A61K31/551—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
- A61K31/5513—1,4-Benzodiazepines, e.g. diazepam or clozapine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/60—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings condensed with carbocyclic rings or ring systems
- C07D277/62—Benzothiazoles
- C07D277/68—Benzothiazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
- C07D277/82—Nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
Abstract
Foreliggende oppfinnelse angår forbindelser med den generelle formel (I) og deres farmasøytisk akseptable salter for behandling av sykdommer relatert til adenosin- reseptoren.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP00113219 | 2000-06-21 | ||
PCT/EP2001/006506 WO2001097786A2 (en) | 2000-06-21 | 2001-06-08 | Benzothiazole derivatives |
Publications (1)
Publication Number | Publication Date |
---|---|
NO20073465L true NO20073465L (no) | 2002-12-12 |
Family
ID=8169041
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO20025978A NO324635B1 (no) | 2000-06-21 | 2002-12-12 | Benzotiazolderivater, fremstilling av disse, anvendelse av slike for fremstilling av medikamenter for behandling av sykdom samt medikament inneholdende slike forbindelser |
NO20073465A NO20073465L (no) | 2000-06-21 | 2007-07-06 | Benzotiazol-derivater |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO20025978A NO324635B1 (no) | 2000-06-21 | 2002-12-12 | Benzotiazolderivater, fremstilling av disse, anvendelse av slike for fremstilling av medikamenter for behandling av sykdom samt medikament inneholdende slike forbindelser |
Country Status (34)
Country | Link |
---|---|
US (8) | US6521754B2 (no) |
EP (2) | EP1303272B1 (no) |
JP (1) | JP3886897B2 (no) |
KR (2) | KR100571161B1 (no) |
CN (1) | CN1234358C (no) |
AR (1) | AR031244A1 (no) |
AT (1) | ATE385794T1 (no) |
AU (2) | AU2001281817B2 (no) |
BR (1) | BR0112395A (no) |
CA (1) | CA2413086C (no) |
CY (1) | CY1107401T1 (no) |
CZ (1) | CZ2003182A3 (no) |
DE (1) | DE60132777T2 (no) |
DK (1) | DK1303272T3 (no) |
EC (1) | ECSP024399A (no) |
ES (1) | ES2299504T3 (no) |
HK (1) | HK1058148A1 (no) |
HR (1) | HRP20020962A2 (no) |
HU (1) | HUP0301315A3 (no) |
IL (2) | IL153278A0 (no) |
JO (1) | JO2503B1 (no) |
MX (1) | MXPA02012596A (no) |
MY (1) | MY138352A (no) |
NO (2) | NO324635B1 (no) |
NZ (1) | NZ522928A (no) |
PE (1) | PE20020104A1 (no) |
PL (1) | PL207384B1 (no) |
PT (1) | PT1303272E (no) |
RU (1) | RU2251419C2 (no) |
SI (1) | SI1303272T1 (no) |
UY (1) | UY26782A1 (no) |
WO (1) | WO2001097786A2 (no) |
YU (1) | YU96502A (no) |
ZA (1) | ZA200209730B (no) |
Families Citing this family (71)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
BR0112395A (pt) * | 2000-06-21 | 2003-07-08 | Hoffmann La Roche | Derivados de benzotiazol |
US6599901B1 (en) * | 2001-11-19 | 2003-07-29 | Hoffman-La Roche Inc. | Pyridone substituted benzothiazole derivatives |
US6620811B2 (en) * | 2001-11-19 | 2003-09-16 | Hoffmann-La Roche Inc. | Isonicotin- and nicotinamide derivatives of benzothiazoles |
CA2467825A1 (en) * | 2001-11-27 | 2003-06-05 | F. Hoffmann-La Roche Ag | Benzothiazole derivatives |
US6624163B2 (en) * | 2001-11-29 | 2003-09-23 | Hoffman-La Roche Inc. | Benzothiazole derivatives |
US6727247B2 (en) * | 2001-12-10 | 2004-04-27 | Hoffman-La Roche Inc. | Substituted benzothiazole amide derivatives |
US6734179B2 (en) * | 2001-12-12 | 2004-05-11 | Hoffmann-La Roche Inc. | Benzothiazoles |
CN1296368C (zh) * | 2001-12-12 | 2007-01-24 | 弗·哈夫曼-拉罗切有限公司 | 用作腺苷受体调节剂的苯并噻吩化合物 |
US6713499B2 (en) | 2001-12-12 | 2004-03-30 | Hoffman-La Roche Inc. | 7-Amino-benzothiazole derivatives |
AU2003207734C1 (en) | 2002-01-28 | 2009-10-08 | Kyowa Kirin Co., Ltd. | Methods of treating patients suffering from movement disorders |
WO2004002531A1 (ja) * | 2002-06-26 | 2004-01-08 | Ono Pharmaceutical Co., Ltd. | 血管の収縮または拡張による疾患治療剤 |
US6958420B2 (en) * | 2002-07-19 | 2005-10-25 | Board Of Trustees Of Michigan State University | Synthesis of aminoarylboronic esters and substituted anilines from arenes via catalytic C-H activation/borylation/amination and uses thereof |
US7338956B2 (en) | 2002-08-07 | 2008-03-04 | Sanofi-Aventis Deutschland Gmbh | Acylamino-substituted heteroaromatic compounds and their use as pharmaceuticals |
AU2003295605A1 (en) | 2002-11-19 | 2004-06-15 | Achillion Pharmaceuticals, Inc. | Substituted aryl thioureas and releated compounds; inhibitors of viral replication |
AR056615A1 (es) * | 2002-12-27 | 2007-10-17 | Kyowa Hakko Kogyo Kk | Un metodo de tratamiento de trastornos de la conducta |
US7087761B2 (en) * | 2003-01-07 | 2006-08-08 | Hoffmann-La Roche Inc. | Cyclization process for substituted benzothiazole derivatives |
PL378343A1 (pl) * | 2003-01-13 | 2006-03-20 | F. Hoffmann-La Roche Ag | Pochodne benzoksazolu i ich zastosowanie jako ligandów receptora adenozyny |
US6872833B2 (en) | 2003-04-14 | 2005-03-29 | Hoffmann-La Roche Inc. | Adenosine receptor ligands |
ATE407133T1 (de) * | 2003-05-13 | 2008-09-15 | Hoffmann La Roche | 2-imidazo-benzothiazole als adenosin-rezeptor liganden |
DK1636223T3 (da) * | 2003-05-19 | 2008-06-23 | Hoffmann La Roche | Benzothiazolderivater som adenosinreceptorligander |
AU2004241720B2 (en) * | 2003-05-21 | 2008-11-06 | F. Hoffmann-La Roche Ag | Benzothiazole derivatives and use thereof in the treatment of diseases related to the adenosine A2A receptor |
CA2527174C (en) * | 2003-05-30 | 2014-03-25 | F.Hoffmann-La Roche Ag | Benzothiazole derivatives and use thereof in the treatment of diseases related to the adenosine a2a receptor |
NZ544674A (en) * | 2003-07-10 | 2009-03-31 | Achillion Pharmaceuticals Inc | Substituted arylthiourea derivatives useful as inhibitors of viral replication |
DK1648879T3 (da) * | 2003-07-24 | 2009-02-23 | Euro Celtique Sa | Heteroaryl-tetrahydropyridyl-forbindelser, der er anvendelige til behandling eller forebyggelse af smerte |
NZ619746A (en) | 2003-08-06 | 2014-05-30 | Senomyx Inc | Novel flavors, flavor modifiers, tastants, taste enhancers, umami or sweet tastants, and/or enhancers and use thereof |
CA2539314A1 (en) * | 2003-09-19 | 2005-03-31 | F. Hoffmann-La Roche Ag | Thiazolopyridine derivatives as adenosine receptor ligands |
TW200600492A (en) * | 2004-05-18 | 2006-01-01 | Achillion Pharmaceuticals Inc | Substituted aryl acylthioureas and related compounds; inhibitors of viral replication |
JP4668265B2 (ja) * | 2004-05-24 | 2011-04-13 | エフ.ホフマン−ラ ロシュ アーゲー | 4−ヒドロキシ−4−メチル−ピペリジン−1−カルボン酸(4−メトキシ−7−モルホリン−4−イル−ベンゾチアゾール−2−イル)−アミド |
KR100834179B1 (ko) * | 2004-05-24 | 2008-05-30 | 에프. 호프만-라 로슈 아게 | 4-하이드록시-4-메틸-피페리딘-1-카복실산(4-메톡시-7-모폴린-4-일-벤조티아졸-2-일)-아마이드 |
WO2006008041A1 (en) * | 2004-07-22 | 2006-01-26 | F. Hoffmann-La Roche Ag | Benzothiazole derivatives |
MX2007000635A (es) * | 2004-07-22 | 2007-03-07 | Hoffmann La Roche | Benzotiazoles sustituidos. |
SE0401970D0 (sv) * | 2004-08-02 | 2004-08-02 | Astrazeneca Ab | Novel compounds |
JP4633123B2 (ja) | 2004-11-05 | 2011-02-16 | エフ.ホフマン−ラ ロシュ アーゲー | イソニコチン酸誘導体の製造方法 |
CN101180299B (zh) | 2005-03-23 | 2010-12-15 | 弗·哈夫曼-拉罗切有限公司 | 作为mglur2拮抗剂的乙炔基-吡唑并嘧啶衍生物 |
TWI370820B (en) | 2005-04-27 | 2012-08-21 | Takeda Pharmaceutical | Fused heterocyclic compounds |
EP1934214B1 (en) | 2005-09-27 | 2010-04-07 | F.Hoffmann-La Roche Ag | Oxadiazolyl pyrazolo-pyrimidines as mglur2 antagonists |
ES2273599B1 (es) | 2005-10-14 | 2008-06-01 | Universidad De Barcelona | Compuestos para el tratamiento de la fibrilacion auricular. |
WO2007098826A2 (en) * | 2006-01-18 | 2007-09-07 | Siena Biotech S.P.A. | Modulators of alpha7 nicotinic acetylcholine receptors and therapeutic uses thereof |
TWI425917B (zh) | 2006-04-21 | 2014-02-11 | Senomyx Inc | 包含高度鮮味風味劑之可食用組合物及其製造方法 |
US7429589B2 (en) | 2006-04-27 | 2008-09-30 | Hoffmann-La Roche Inc. | Mono-nitration of aromatic compounds via nitrate salts |
AU2007253485B2 (en) * | 2006-05-18 | 2010-07-08 | F. Hoffmann-La Roche Ag | Thiazolo-pyramidine / pyridine urea derivatives as adenosine A2B receptor antagonists |
US8481544B2 (en) | 2006-06-22 | 2013-07-09 | Biota Europe Limited | Antibacterial compositions |
GB0612428D0 (en) * | 2006-06-22 | 2006-08-02 | Prolysis Ltd | Antibacterial agents |
WO2008077809A1 (en) * | 2006-12-22 | 2008-07-03 | F. Hoffmann-La Roche Ag | Process for the manufacture of 7-oxa-bicyclo derivatives |
EP2139907B1 (en) | 2007-02-14 | 2013-08-14 | Basf Se | Electroluminescent metal complex |
PE20130325A1 (es) | 2007-04-27 | 2013-03-18 | Purdue Pharma Lp | Derivados de piperidina, piperazina o tetrahidropiridilo como antagonistas de trpv1 |
WO2009015236A1 (en) * | 2007-07-23 | 2009-01-29 | Synosia Therapeutics | 4-hydroxy-4-methyl-piperidine-1-carboxylic acid (4-methoxy-7-morpholin-4-yl-benzothiazol-2-yl)-amide for the treatment of post-traumatic stress disorder |
US7913765B2 (en) * | 2007-10-19 | 2011-03-29 | Baker Hughes Incorporated | Water absorbing or dissolving materials used as an in-flow control device and method of use |
GB0724342D0 (en) | 2007-12-13 | 2008-01-30 | Prolysis Ltd | Anitbacterial compositions |
JO3101B1 (ar) | 2008-12-02 | 2017-09-20 | Takeda Pharmaceuticals Co | مشتقات بنزوثيازول كعوامل مضادة للسرطان |
KR101064258B1 (ko) * | 2008-12-29 | 2011-09-14 | 한국과학기술연구원 | 벤조아릴우레이도 화합물, 및 이를 함유하는 퇴행성 뇌질환예방 또는 치료용 조성물 |
US8168785B2 (en) | 2009-06-17 | 2012-05-01 | Biotie Therapies, Inc. | Benzothiazole derivatives |
WO2010150927A1 (en) * | 2009-06-25 | 2010-12-29 | Sk Holdings Co., Ltd. | Pharmaceutical composition for prevention and treatment of cancer diseases comprising benzamide derivatives |
RU2455293C2 (ru) * | 2010-09-15 | 2012-07-10 | Государственное образовательное учреждение высшего профессионального образования "Пермская государственная фармацевтическая академия Федерального агентства по здравоохранению и социальному развитию" (ГОУ ВПО ПГФА Росздрава) | N-(2-бензотиазолил)амид 3-бром-2,4-диоксо-4-(4-метоксифенил)бутановой кислоты, обладающий гипогликемической активностью |
RU2448100C1 (ru) * | 2010-09-24 | 2012-04-20 | Татьяна Николаевна Иванова | Производные 2-аминобензотиазола, обладающие противогипоксической активностью, и способ их использования |
JP5769326B2 (ja) * | 2010-10-19 | 2015-08-26 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | Rhoキナーゼ阻害薬 |
DE102011005232A1 (de) | 2011-03-08 | 2012-09-13 | AristoCon GmbH & Co. KG | Adenosin und seine Derivate zur Verwendung in der Schmerztherapie |
UA113288C2 (xx) | 2011-06-22 | 2017-01-10 | Trpv1 антагоністи, що містять дигідроксизамісник, і їх застосування | |
TWI571466B (zh) * | 2011-10-14 | 2017-02-21 | 艾伯維有限公司 | 用於治療癌症及免疫與自體免疫疾病之細胞凋亡誘發劑 |
CN103772376B (zh) * | 2012-10-24 | 2017-01-11 | 中国医学科学院医药生物技术研究所 | 取代的苯并-1,3-杂唑类化合物、其制备方法及用途 |
US9988374B2 (en) | 2014-08-11 | 2018-06-05 | Angion Biomedica Corp. | Cytochrome P450 inhibitors and uses thereof |
AU2015374231B2 (en) * | 2014-12-31 | 2020-07-23 | Angion Biomedica Corp. | Methods and agents for treating disease |
WO2017066225A1 (en) * | 2015-10-14 | 2017-04-20 | Texas Tech University System | Pharmacoperones of the v2 receptor |
EP3512602B1 (en) * | 2016-09-16 | 2024-03-27 | HSF Pharmaceuticals | Inhibitors of heat shock factors (hsf) and uses thereof |
AU2018309265B2 (en) * | 2017-08-01 | 2022-06-02 | Merck Patent Gmbh | Thiazolopyridine derivatives as adenosine receptor antagonists |
RU2748993C1 (ru) * | 2017-09-28 | 2021-06-02 | СиСТОУН ФАРМАСЬЮТИКАЛС (СУЧЖОУ) КО., ЛТД. | Производное с конденсированным кольцом в качестве ингибитора рецептора a2a |
AR117844A1 (es) * | 2019-01-22 | 2021-09-01 | Merck Patent Gmbh | Derivados de tiazolopiridina como antagonistas del receptor de adenosina |
DE102019110904B4 (de) * | 2019-04-26 | 2022-01-20 | Helmholtz-Zentrum Dresden - Rossendorf E. V. | N-(4-methoxy-7-morpholinobenzo[d]thiazol-2-yl)-acetamid-Derivate und deren Verwendung |
CA3162227A1 (en) * | 2019-12-16 | 2021-06-24 | David Scott Grierson | Antiviral compounds, compositions and methods of use |
WO2021247921A1 (en) * | 2020-06-03 | 2021-12-09 | Yumanity Therapeutics, Inc. | Benzothiazole compounds and uses thereof |
CN116829542A (zh) * | 2021-01-29 | 2023-09-29 | 韩国化学研究院 | 苯并噻唑及苯并咪唑衍生物、药学上可接受的盐、其制备方法以及包含其作为活性成分的药物组合物 |
Family Cites Families (37)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CH505543A (de) | 1968-11-01 | 1971-04-15 | Ciba Geigy Ag | Schädlingsbekämpfungsmittel |
GB1318291A (en) * | 1970-04-15 | 1973-05-23 | Shell Int Research | Carboxamide derivatives and fungicidal compositions containing them |
LU63457A1 (no) * | 1970-07-06 | 1971-11-12 | ||
JPS5516147B2 (no) * | 1971-12-24 | 1980-04-30 | ||
US4028374A (en) * | 1975-11-03 | 1977-06-07 | Morton-Norwich Products, Inc. | Antibacterial thiocyanatobenzothiazoles |
DE2656468A1 (de) * | 1976-12-14 | 1978-06-15 | Boehringer Mannheim Gmbh | N-(benzthiazol-2-yl)-oxamidsaeure- derivate und verfahren zu ihrer herstellung |
US4471957A (en) * | 1979-12-03 | 1984-09-18 | Baltimore Therapeutic Equipment Company | Method and apparatus for rehabilitation of damaged limbs |
CA1153867A (en) | 1980-05-16 | 1983-09-20 | Michael A. M. Boersma | Process for the preparation of crystalline silicates, crystalline silicates so prepared and process for carrying out catalytic reactions |
KR930005004B1 (ko) * | 1985-04-15 | 1993-06-11 | 쟈안센 파아마슈우티카 엔. 부이. | 치환된 n-[(4-피페리디닐)알킬]이환 축합 옥사졸아민 및 티아졸아민의 제조방법 |
FI91859C (fi) | 1987-06-17 | 1994-08-25 | Eisai Co Ltd | Analogiamenetelmä antiallergisena aineena aktiivisen bentsotiatsolijohdannaisen valmistamiseksi |
EP0300688A1 (en) * | 1987-07-21 | 1989-01-25 | FISONS plc | Pyrrole derivatives, process for their preparation and pharmaceutical compositions containing them |
US5348519A (en) * | 1988-02-04 | 1994-09-20 | Loredan Biomedical, Inc. | Exercise and diagnostic apparatus and method |
IL90337A0 (en) * | 1988-05-24 | 1989-12-15 | Pfizer | Aromatic and heterocyclic carboxamide derivatives as antineoplastic agents |
JPH0667923B2 (ja) | 1989-05-11 | 1994-08-31 | 東洋紡績株式会社 | 新規なベンゾチアゾール誘導体 |
WO1990015801A1 (en) * | 1989-06-22 | 1990-12-27 | Pfizer Inc. | Substituted sulfonamides and related compounds in the treatment of asthma, arthritis and related diseases |
DE59005183D1 (de) | 1989-11-10 | 1994-05-05 | Agrolinz Agrarchemikalien | Verfahren zur Herstellung reiner, unsymmetrisch disubstituierter Harnstoffe. |
US5142910A (en) * | 1990-06-27 | 1992-09-01 | Occupational Orthopaedic Systems, Inc. | Dynamic physiological function testing apparatus and method |
ATE132486T1 (de) * | 1990-10-15 | 1996-01-15 | Pfizer | Pyrrolidin-dionderivate |
US5275045A (en) * | 1991-03-07 | 1994-01-04 | Isotechnologies, Inc. | Apparatus and method for use in assessing the lifting capability of a human subject |
CN1038586C (zh) * | 1991-05-01 | 1998-06-03 | 大制药株式会社 | 吡嗪衍生物的制备方法 |
EP0604657B1 (en) * | 1992-05-21 | 2000-01-12 | Otsuka Pharmaceutical Factory, Inc. | Phosphonic diester derivative |
US5312107A (en) * | 1993-05-13 | 1994-05-17 | Kordun, Ltd. | Golf club swing training and exercise device |
JPH0725858A (ja) * | 1993-07-13 | 1995-01-27 | Otsuka Pharmaceut Co Ltd | ピペラジン誘導体 |
JPH0940646A (ja) * | 1995-07-27 | 1997-02-10 | Yamanouchi Pharmaceut Co Ltd | ベンゼン縮合環誘導体又はその塩 |
FR2753970B1 (fr) | 1996-10-01 | 1998-10-30 | Synthelabo | Derives de n-(benzothiazol-2-yl) piperidine-1-ethanamine, leur preparation et leur application en therapeutique |
JPH11130761A (ja) * | 1997-10-24 | 1999-05-18 | Otsuka Pharmaceut Co Ltd | ベンゾチアゾール誘導体 |
TR200001312T2 (tr) * | 1997-11-10 | 2000-09-21 | Bristol-Myers Squibb Company | Benzotiyazol protein tirozin kinaz önleyicileri. |
AU1924099A (en) * | 1997-12-18 | 1999-07-05 | Lyonnaise Industrielle Pharmaceutique (Lipha) | Piperazine derivatives useful as hypoglycemic agents |
CA2318969A1 (en) * | 1998-01-23 | 1999-07-29 | Mikhail F. Gordeev | Oxazolidinone combinatorial libraries, compositions and methods of preparation |
CN1325397A (zh) | 1998-09-30 | 2001-12-05 | 纽罗根公司 | 2-哌嗪烷基氨基苯并吡咯衍生物∶多巴胺受体亚型特异配体 |
UA71587C2 (uk) * | 1998-11-10 | 2004-12-15 | Шерінг Акцієнгезелльшафт | Аміди антранілової кислоти та їхнє застосування як лікарських засобів |
JP2002533453A (ja) * | 1998-12-23 | 2002-10-08 | イーライ・リリー・アンド・カンパニー | Xa因子のインヒビターとしてのヘテロ芳香族アミド |
IL133680A0 (en) * | 1999-09-10 | 2001-04-30 | Can Fite Technologies Ltd | Pharmaceutical compositions comprising an adenosine receptor agonist or antagonist |
JP2003534239A (ja) * | 1999-12-17 | 2003-11-18 | ヴァージコア・インコーポレーテッド | 新規なスクシナート化合物、組成物、並びに使用及び調製方法 |
BR0112395A (pt) * | 2000-06-21 | 2003-07-08 | Hoffmann La Roche | Derivados de benzotiazol |
US6620811B2 (en) * | 2001-11-19 | 2003-09-16 | Hoffmann-La Roche Inc. | Isonicotin- and nicotinamide derivatives of benzothiazoles |
US6727247B2 (en) * | 2001-12-10 | 2004-04-27 | Hoffman-La Roche Inc. | Substituted benzothiazole amide derivatives |
-
2001
- 2001-06-08 BR BR0112395-5A patent/BR0112395A/pt not_active IP Right Cessation
- 2001-06-08 ES ES01960284T patent/ES2299504T3/es not_active Expired - Lifetime
- 2001-06-08 CA CA2413086A patent/CA2413086C/en not_active Expired - Fee Related
- 2001-06-08 CZ CZ2003182A patent/CZ2003182A3/cs unknown
- 2001-06-08 KR KR1020027017432A patent/KR100571161B1/ko not_active IP Right Cessation
- 2001-06-08 DE DE60132777T patent/DE60132777T2/de not_active Expired - Lifetime
- 2001-06-08 JP JP2002503263A patent/JP3886897B2/ja not_active Expired - Fee Related
- 2001-06-08 IL IL15327801A patent/IL153278A0/xx unknown
- 2001-06-08 SI SI200130813T patent/SI1303272T1/sl unknown
- 2001-06-08 HU HU0301315A patent/HUP0301315A3/hu unknown
- 2001-06-08 YU YU96502A patent/YU96502A/sh unknown
- 2001-06-08 AU AU2001281817A patent/AU2001281817B2/en not_active Ceased
- 2001-06-08 EP EP01960284A patent/EP1303272B1/en not_active Expired - Lifetime
- 2001-06-08 EP EP07003532A patent/EP1797878A3/en not_active Withdrawn
- 2001-06-08 CN CNB018115349A patent/CN1234358C/zh not_active Expired - Fee Related
- 2001-06-08 AT AT01960284T patent/ATE385794T1/de active
- 2001-06-08 KR KR10-2005-7002723A patent/KR100526487B1/ko not_active IP Right Cessation
- 2001-06-08 MX MXPA02012596A patent/MXPA02012596A/es active IP Right Grant
- 2001-06-08 NZ NZ522928A patent/NZ522928A/en unknown
- 2001-06-08 AU AU8181701A patent/AU8181701A/xx active Pending
- 2001-06-08 PT PT01960284T patent/PT1303272E/pt unknown
- 2001-06-08 WO PCT/EP2001/006506 patent/WO2001097786A2/en active IP Right Grant
- 2001-06-08 RU RU2003100518/15A patent/RU2251419C2/ru not_active IP Right Cessation
- 2001-06-08 PL PL360697A patent/PL207384B1/pl not_active IP Right Cessation
- 2001-06-08 DK DK01960284T patent/DK1303272T3/da active
- 2001-06-14 US US09/881,252 patent/US6521754B2/en not_active Expired - Fee Related
- 2001-06-14 JO JO200194A patent/JO2503B1/en active
- 2001-06-18 PE PE2001000587A patent/PE20020104A1/es not_active Application Discontinuation
- 2001-06-19 AR ARP010102899A patent/AR031244A1/es unknown
- 2001-06-19 MY MYPI20012891A patent/MY138352A/en unknown
- 2001-06-20 UY UY26782A patent/UY26782A1/es not_active Application Discontinuation
-
2002
- 2002-11-29 ZA ZA200209730A patent/ZA200209730B/en unknown
- 2002-12-04 IL IL153278A patent/IL153278A/en not_active IP Right Cessation
- 2002-12-05 US US10/310,508 patent/US6835732B2/en not_active Expired - Fee Related
- 2002-12-05 HR HR20020962A patent/HRP20020962A2/xx not_active Application Discontinuation
- 2002-12-12 NO NO20025978A patent/NO324635B1/no not_active IP Right Cessation
- 2002-12-18 US US10/322,272 patent/US6963000B2/en not_active Expired - Fee Related
- 2002-12-20 EC EC2002004399A patent/ECSP024399A/es unknown
-
2004
- 2004-02-12 HK HK04100949A patent/HK1058148A1/xx not_active IP Right Cessation
- 2004-08-30 US US10/930,361 patent/US20050026906A1/en not_active Abandoned
-
2005
- 2005-09-02 US US11/219,577 patent/US7317007B2/en not_active Expired - Lifetime
-
2007
- 2007-07-06 NO NO20073465A patent/NO20073465L/no not_active Application Discontinuation
- 2007-10-31 US US11/930,799 patent/US20080108809A1/en not_active Abandoned
- 2007-10-31 US US11/930,717 patent/US20080125419A1/en not_active Abandoned
-
2008
- 2008-04-18 CY CY20081100435T patent/CY1107401T1/el unknown
-
2009
- 2009-12-01 US US12/628,243 patent/US20100075959A1/en not_active Abandoned
Also Published As
Similar Documents
Publication | Publication Date | Title |
---|---|---|
NO20073465L (no) | Benzotiazol-derivater | |
NO20021328L (no) | Pyrazolopyrimidier som terapeutiske midler | |
NO20054905L (no) | 2-acylamino-4-fenyltiazolderivater, fremgangsmate for deres fremstilling og anvendelse av de samme som i terapeutika | |
NO20054848L (no) | Substituerte p-diaminobenzenderivater | |
NO20060981L (no) | Pyridazinderivater og deres anvendelse som terapeutiske midler | |
JO2282B1 (en) | Oxazole derivatives | |
NO20064599L (no) | Substituerte morfolin- og tiomorfolinderivater | |
NO20053748L (no) | Pyrrolopyridazinderivater. | |
NO20050851L (no) | Kaspase-inhibitorer og anvendelser derav | |
NO20055421L (no) | Kinolinderivater som fosfodiestrase-inhibitorer | |
NO20052796L (no) | Indolylpyrazinonderivater anvendelige for behandling av hyper-proliferative forstyrrelser og sykdommer assosiert med angiogenese | |
NO20055562L (no) | Substituerte indolin- og indolderivater | |
NO20051263L (no) | Ny anvendelse av benzotiazolderivater | |
NO20081844L (no) | Terapeutiske forbindelser | |
NO20062136L (no) | Imidazopyrazintyrosin-kinaseinhibitorer | |
NO20062713L (no) | 2,6 bisheteroaryl-4-aminopyrimidiner som adenosin reseptor antagonister | |
DE60206911D1 (de) | Imidazol-2-carbonsäureamid derivate als raf-kinase-inhibitoren | |
NO20050666L (no) | 2,7-substituerte indoler og deres anvendelse som 5-HT6 modulatorer | |
ATE384058T1 (de) | Thiazolderivate | |
NO20081942L (no) | Karbamoylbenzotriazolderivater som inhibitorer av lipaser og fosfolipaser | |
NO20052699L (no) | 4(fenylpiperazinyl-metyl)benzamid-derivater og deres anvendelse ved behandling av smerte og gastrointestinale lidelser. | |
NO20062599L (no) | Fremgangsmate for syntese av perindopril og farmasoytisk akseptable salter derav | |
NO20092035L (no) | Tiazolylforbindelser anvendbare som kinaseinhibitorer | |
NO20034301L (no) | Cyano-substituerte dihydropyrimidin forbindelser | |
NO20054721L (no) | Substituerte anilinderivater |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
FC2A | Withdrawal, rejection or dismissal of laid open patent application |