FR2753970B1 - Derives de n-(benzothiazol-2-yl) piperidine-1-ethanamine, leur preparation et leur application en therapeutique - Google Patents

Derives de n-(benzothiazol-2-yl) piperidine-1-ethanamine, leur preparation et leur application en therapeutique

Info

Publication number
FR2753970B1
FR2753970B1 FR9611925A FR9611925A FR2753970B1 FR 2753970 B1 FR2753970 B1 FR 2753970B1 FR 9611925 A FR9611925 A FR 9611925A FR 9611925 A FR9611925 A FR 9611925A FR 2753970 B1 FR2753970 B1 FR 2753970B1
Authority
FR
France
Prior art keywords
benzothiazol
piperidine
preparation
therapeutic application
ethanamine derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
FR9611925A
Other languages
English (en)
Other versions
FR2753970A1 (fr
Inventor
Gihad Dargazanli
Pascal George
Patrick Lardenois
Jonathan Frost
Johannes Schoemaker
Maria Carmen Renones
Pascale Magat
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Synthelabo SA
Original Assignee
Synthelabo SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to FR9611925A priority Critical patent/FR2753970B1/fr
Application filed by Synthelabo SA filed Critical Synthelabo SA
Priority to IL12890297A priority patent/IL128902A/en
Priority to CO97056315A priority patent/CO4650030A1/es
Priority to AU44638/97A priority patent/AU722147B2/en
Priority to NZ334553A priority patent/NZ334553A/xx
Priority to SK422-99A priority patent/SK42299A3/sk
Priority to EEP199900135A priority patent/EE9900135A/xx
Priority to CN97198112A priority patent/CN1230959A/zh
Priority to JP10516272A priority patent/JP2001501217A/ja
Priority to KR1019990702753A priority patent/KR20000048767A/ko
Priority to PCT/FR1997/001692 priority patent/WO1998014444A1/fr
Priority to BR9711842A priority patent/BR9711842A/pt
Priority to CZ991126A priority patent/CZ112699A3/cs
Priority to HU9904091A priority patent/HUP9904091A3/hu
Priority to EP97943001A priority patent/EP0929550A1/fr
Priority to PL97332648A priority patent/PL332648A1/xx
Priority to CA002266510A priority patent/CA2266510A1/fr
Priority to TR1999/00634T priority patent/TR199900634T2/xx
Priority to ZA9708772A priority patent/ZA978772B/xx
Priority to TW086114229A priority patent/TW438800B/zh
Priority to ARP970104493A priority patent/AR009105A1/es
Publication of FR2753970A1 publication Critical patent/FR2753970A1/fr
Publication of FR2753970B1 publication Critical patent/FR2753970B1/fr
Application granted granted Critical
Priority to BG103271A priority patent/BG103271A/xx
Priority to NO991581A priority patent/NO991581L/no
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
FR9611925A 1996-10-01 1996-10-01 Derives de n-(benzothiazol-2-yl) piperidine-1-ethanamine, leur preparation et leur application en therapeutique Expired - Fee Related FR2753970B1 (fr)

Priority Applications (23)

Application Number Priority Date Filing Date Title
FR9611925A FR2753970B1 (fr) 1996-10-01 1996-10-01 Derives de n-(benzothiazol-2-yl) piperidine-1-ethanamine, leur preparation et leur application en therapeutique
PL97332648A PL332648A1 (en) 1996-10-01 1997-09-26 Derivatives of n-(2-benzothiazolyl)-1-piperidinethane mine, their production and application in medical therapy
HU9904091A HUP9904091A3 (en) 1996-10-01 1997-09-26 N-(benzothiazol-2-yl) piperidine-1-ethanamine derivatives, their preparation and application in therapeutics
NZ334553A NZ334553A (en) 1996-10-01 1997-09-26 N-(2-Benzothiazolyl) piperidine-1 ethanamine derivatives and pharmaceutical use
SK422-99A SK42299A3 (en) 1996-10-01 1997-09-26 N-(benzothiazol-2-yl) piperidine-1-ethanamine derivatives, their preparation and application in therapeutics
EEP199900135A EE9900135A (et) 1996-10-01 1997-09-26 N-(2-bensotiasolüül)-1-piperidiinetaanamiini derivaadid, nende valmistamine ja kasutamine raviks
CN97198112A CN1230959A (zh) 1996-10-01 1997-09-26 N－(2－苯并噻唑基)－1－哌啶乙胺衍生物,其制备方法及其在治疗中的应用
JP10516272A JP2001501217A (ja) 1996-10-01 1997-09-26 Ｎ―（ベンゾチアゾール―２―イル）―１―ピペリジンエタナミン誘導体、その製法および治療的応用
KR1019990702753A KR20000048767A (ko) 1996-10-01 1997-09-26 Ｎ-(벤조티아졸-2-일)-1-피페리딘에탄아민 유도체, 그의 제법 및치료에의 응용
CO97056315A CO4650030A1 (es) 1996-10-01 1997-09-26 Derivados de n-(benzotiazol-2-il) piperidina-1-etanamina, proceso para su preparacion y producto farmaceutico que los contiene
BR9711842A BR9711842A (pt) 1996-10-01 1997-09-26 Derivados de n-(benzotiazol-2-il) piperidina-1-etanamina sua prepara-Æo e sua aplica-Æo em terap-utica
CZ991126A CZ112699A3 (cs) 1996-10-01 1997-09-26 Deriváty N-(2-benzothiazolyl)-1-piperidinethanaminu, způsob jejich výroby a farmaceutické prostředky, které je obsahují
IL12890297A IL128902A (en) 1996-10-01 1997-09-26 History - N- (2-Benzothiazol) - 1 piperidinethanamine, their preparation and pharmaceutical preparations containing them
AU44638/97A AU722147B2 (en) 1996-10-01 1997-09-26 N-(benzothiazol-2-yl) piperidine-1-ethanamine derivatives, their preparation and application in therapeutics
EP97943001A EP0929550A1 (fr) 1996-10-01 1997-09-26 DERIVES DE $i(N)-(BENZOTHIAZOL-2-YL)PIPERIDINE-1-ETHANAMINE, LEUR PREPARATION ET LEUR APPLICATION EN THERAPEUTIQUE
CA002266510A CA2266510A1 (fr) 1996-10-01 1997-09-26 Derives de n-(benzothiazol-2-yl)piperidine-1-ethanamine, leur preparation et leur application en therapeutique
TR1999/00634T TR199900634T2 (xx) 1996-10-01 1997-09-26 N-(Benzotiazol-2-il) Piperidin-1-etanamin t�revleri, haz�rlanmalar� ve terapide uygulanmas�.
PCT/FR1997/001692 WO1998014444A1 (fr) 1996-10-01 1997-09-26 Derives de n-(benzothiazol-2-yl)piperidine-1-ethanamine, leur preparation et leur application en therapeutique
TW086114229A TW438800B (en) 1996-10-01 1997-09-30 N-(2-benzothiazolyl)-1-piperidineethanamine derivatives, their preparation and their use in therapy
ZA9708772A ZA978772B (en) 1996-10-01 1997-09-30 N-(2-benzothiazolyl)-1-piperidineethanamine derivatives, their preparation and their use in therapy.
ARP970104493A AR009105A1 (es) 1996-10-01 1997-09-30 Derivados de n-(benzotiazol-2-il) piperidina-1-etanamina, su preparacion y aplicacion en terapeutica
BG103271A BG103271A (en) 1996-10-01 1999-03-22 Derivatives of n-(benzothiazol-2-yl) piperidine-1-ethaneamines, method for their preparation and application as therapeutical means
NO991581A NO991581L (no) 1996-10-01 1999-03-30 N-(benzotiazol-2-yl)piperidin-1-etanaminderivater, deres fremstilling og anvendelse i terapeutiske midler

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9611925A FR2753970B1 (fr) 1996-10-01 1996-10-01 Derives de n-(benzothiazol-2-yl) piperidine-1-ethanamine, leur preparation et leur application en therapeutique

Publications (2)

Publication Number Publication Date
FR2753970A1 FR2753970A1 (fr) 1998-04-03
FR2753970B1 true FR2753970B1 (fr) 1998-10-30

Family

ID=9496217

Family Applications (1)

Application Number Title Priority Date Filing Date
FR9611925A Expired - Fee Related FR2753970B1 (fr) 1996-10-01 1996-10-01 Derives de n-(benzothiazol-2-yl) piperidine-1-ethanamine, leur preparation et leur application en therapeutique

Country Status (23)

Country Link
EP (1) EP0929550A1 (fr)
JP (1) JP2001501217A (fr)
KR (1) KR20000048767A (fr)
CN (1) CN1230959A (fr)
AR (1) AR009105A1 (fr)
AU (1) AU722147B2 (fr)
BG (1) BG103271A (fr)
BR (1) BR9711842A (fr)
CA (1) CA2266510A1 (fr)
CO (1) CO4650030A1 (fr)
CZ (1) CZ112699A3 (fr)
EE (1) EE9900135A (fr)
FR (1) FR2753970B1 (fr)
HU (1) HUP9904091A3 (fr)
IL (1) IL128902A (fr)
NO (1) NO991581L (fr)
NZ (1) NZ334553A (fr)
PL (1) PL332648A1 (fr)
SK (1) SK42299A3 (fr)
TR (1) TR199900634T2 (fr)
TW (1) TW438800B (fr)
WO (1) WO1998014444A1 (fr)
ZA (1) ZA978772B (fr)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9725541D0 (en) * 1997-12-02 1998-02-04 Pharmacia & Upjohn Spa Amino-benzothiazole derivatives
US6107313A (en) * 1998-10-02 2000-08-22 Combichem, Inc. Dopamine receptor antagonists
CN1234358C (zh) 2000-06-21 2006-01-04 弗·哈夫曼-拉罗切有限公司 苯并噻唑衍生物
US7087761B2 (en) 2003-01-07 2006-08-08 Hoffmann-La Roche Inc. Cyclization process for substituted benzothiazole derivatives
CA2543419A1 (fr) * 2003-10-24 2005-05-06 Leyi Gong Antagonistes du recepteur ccr3
CN1956983B (zh) 2004-05-24 2010-05-26 弗·哈夫曼-拉罗切有限公司 4-羟基-4-甲基-哌啶-1-甲酸(4-甲氧基-7-吗啉-4-基-苯并噻唑-2-基)-酰胺
WO2006048172A1 (fr) 2004-11-05 2006-05-11 F. Hoffmann-La Roche Ag Procede pour preparer des derives d'acide isonicotinique
CA2602444C (fr) 2005-03-23 2013-03-19 F.Hoffmann-La Roche Ag Derives d'acetylenyl-pyrazolo-pyrimidine comme antagonistes mglur2
BRPI0616571A2 (pt) 2005-09-27 2011-06-21 Hoffmann La Roche oxadiazolil pirazol-piridiminas como antagonistas de mglur2, processo para sua preparação, composição farmacêutica que os contém e uso dos mesmo

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1260474A (fr) * 1984-12-03 1989-09-26 Raymond A. Stokbroekx Derives de benzoxazol- et de benzothiazolamine
KR930005004B1 (ko) * 1985-04-15 1993-06-11 쟈안센 파아마슈우티카 엔. 부이. 치환된 n-[(4-피페리디닐)알킬]이환 축합 옥사졸아민 및 티아졸아민의 제조방법

Also Published As

Publication number Publication date
CZ112699A3 (cs) 1999-06-16
EP0929550A1 (fr) 1999-07-21
BG103271A (en) 2000-05-31
HUP9904091A3 (en) 2000-07-28
CN1230959A (zh) 1999-10-06
EE9900135A (et) 1999-12-15
NO991581D0 (no) 1999-03-30
BR9711842A (pt) 1999-08-24
KR20000048767A (ko) 2000-07-25
IL128902A (en) 2001-07-24
IL128902A0 (en) 2000-02-17
TW438800B (en) 2001-06-07
NO991581L (no) 1999-06-01
AR009105A1 (es) 2000-03-08
PL332648A1 (en) 1999-09-27
ZA978772B (en) 1998-03-27
AU4463897A (en) 1998-04-24
SK42299A3 (en) 1999-12-10
CO4650030A1 (es) 1998-09-03
TR199900634T2 (xx) 1999-06-21
FR2753970A1 (fr) 1998-04-03
WO1998014444A1 (fr) 1998-04-09
JP2001501217A (ja) 2001-01-30
HUP9904091A2 (hu) 2000-05-28
NZ334553A (en) 2000-11-24
AU722147B2 (en) 2000-07-20
CA2266510A1 (fr) 1998-04-09

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Legal Events

Date Code Title Description
TP Transmission of property
TP Transmission of property
ST Notification of lapse