NZ334553A - N-(2-Benzothiazolyl) piperidine-1 ethanamine derivatives and pharmaceutical use - Google Patents

N-(2-Benzothiazolyl) piperidine-1 ethanamine derivatives and pharmaceutical use

Info

Publication number
NZ334553A
NZ334553A NZ334553A NZ33455397A NZ334553A NZ 334553 A NZ334553 A NZ 334553A NZ 334553 A NZ334553 A NZ 334553A NZ 33455397 A NZ33455397 A NZ 33455397A NZ 334553 A NZ334553 A NZ 334553A
Authority
NZ
New Zealand
Prior art keywords
benzothiazolyl
piperidine
pharmaceutical use
ethanamine derivatives
ethanamine
Prior art date
Application number
NZ334553A
Inventor
Gihad Dargazanli
Pascal George
Patrick Lardenois
Jonathan Frost
Johannes Schoemaker
Maria-Carmen Renones
Pascale Magat
Original Assignee
Sanofi Synthelabo
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Synthelabo filed Critical Sanofi Synthelabo
Publication of NZ334553A publication Critical patent/NZ334553A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Neurosurgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)

Abstract

The compounds of formula (I) may have therapeutical applications, for example in the treatment of neurodegenerative disorders, cerebrovascular disorders or psychoses. In formula (I); n represents 0, 1, 2 or 3; R1 represents a hydrogen or halogen atom or a methyl or methoxy group; R2 represents a hydrogen atom or methyl group; and R3 represents a hydrogen atom or one or two halogen atoms.
NZ334553A 1996-10-01 1997-09-26 N-(2-Benzothiazolyl) piperidine-1 ethanamine derivatives and pharmaceutical use NZ334553A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9611925A FR2753970B1 (en) 1996-10-01 1996-10-01 N- (BENZOTHIAZOL-2-YL) PIPERIDINE-1-ETHANAMINE DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION
PCT/FR1997/001692 WO1998014444A1 (en) 1996-10-01 1997-09-26 N-(benzothiazol-2-yl) piperidine-1-ethanamine derivatives, their preparation and application in therapeutics

Publications (1)

Publication Number Publication Date
NZ334553A true NZ334553A (en) 2000-11-24

Family

ID=9496217

Family Applications (1)

Application Number Title Priority Date Filing Date
NZ334553A NZ334553A (en) 1996-10-01 1997-09-26 N-(2-Benzothiazolyl) piperidine-1 ethanamine derivatives and pharmaceutical use

Country Status (23)

Country Link
EP (1) EP0929550A1 (en)
JP (1) JP2001501217A (en)
KR (1) KR20000048767A (en)
CN (1) CN1230959A (en)
AR (1) AR009105A1 (en)
AU (1) AU722147B2 (en)
BG (1) BG103271A (en)
BR (1) BR9711842A (en)
CA (1) CA2266510A1 (en)
CO (1) CO4650030A1 (en)
CZ (1) CZ112699A3 (en)
EE (1) EE9900135A (en)
FR (1) FR2753970B1 (en)
HU (1) HUP9904091A3 (en)
IL (1) IL128902A (en)
NO (1) NO991581L (en)
NZ (1) NZ334553A (en)
PL (1) PL332648A1 (en)
SK (1) SK42299A3 (en)
TR (1) TR199900634T2 (en)
TW (1) TW438800B (en)
WO (1) WO1998014444A1 (en)
ZA (1) ZA978772B (en)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9725541D0 (en) * 1997-12-02 1998-02-04 Pharmacia & Upjohn Spa Amino-benzothiazole derivatives
US6107313A (en) * 1998-10-02 2000-08-22 Combichem, Inc. Dopamine receptor antagonists
ATE385794T1 (en) 2000-06-21 2008-03-15 Hoffmann La Roche BENZOTHIAZOLE DERIVATIVES FOR THE TREATMENT OF ALZHEIMER'S AND PARKINSON'S
US7087761B2 (en) 2003-01-07 2006-08-08 Hoffmann-La Roche Inc. Cyclization process for substituted benzothiazole derivatives
CA2543419A1 (en) * 2003-10-24 2005-05-06 Leyi Gong Ccr3 receptor antagonists
EP1753760B1 (en) 2004-05-24 2008-01-02 F.Hoffmann-La Roche Ag 4-hydroxy-4-methyl-piperidine-1-carboxylic acid (4-methoxy-7-morpholin-4-yl-benzothiazol-2-yl)-amide
CA2586931C (en) 2004-11-05 2013-08-06 Paul Spurr Process for preparation of isonicotinic acid derivatives
KR100973609B1 (en) 2005-03-23 2010-08-03 에프. 호프만-라 로슈 아게 Acetylenyl-pyrazolo-pyrimidine derivatives as mglur2 antagonists
WO2007039439A1 (en) 2005-09-27 2007-04-12 F.Hoffmann-La Roche Ag Oxadiazolyl pyrazolo-pyrimidines as mglur2 antagonists

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1260474A (en) * 1984-12-03 1989-09-26 Raymond A. Stokbroekx Benzoxazol- and benzothiazolamine derivatives
KR930005004B1 (en) * 1985-04-15 1993-06-11 쟈안센 파아마슈우티카 엔. 부이. Process for preparing substituted n-|(4-piperidinyl) alkyl¨ bicycle condensed oxazole and thiazolamines

Also Published As

Publication number Publication date
AR009105A1 (en) 2000-03-08
EP0929550A1 (en) 1999-07-21
EE9900135A (en) 1999-12-15
PL332648A1 (en) 1999-09-27
HUP9904091A2 (en) 2000-05-28
BR9711842A (en) 1999-08-24
WO1998014444A1 (en) 1998-04-09
CO4650030A1 (en) 1998-09-03
AU722147B2 (en) 2000-07-20
SK42299A3 (en) 1999-12-10
FR2753970A1 (en) 1998-04-03
CZ112699A3 (en) 1999-06-16
NO991581D0 (en) 1999-03-30
BG103271A (en) 2000-05-31
IL128902A0 (en) 2000-02-17
TW438800B (en) 2001-06-07
CA2266510A1 (en) 1998-04-09
NO991581L (en) 1999-06-01
FR2753970B1 (en) 1998-10-30
AU4463897A (en) 1998-04-24
IL128902A (en) 2001-07-24
TR199900634T2 (en) 1999-06-21
CN1230959A (en) 1999-10-06
JP2001501217A (en) 2001-01-30
HUP9904091A3 (en) 2000-07-28
KR20000048767A (en) 2000-07-25
ZA978772B (en) 1998-03-27

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