NO20070945L - Induksjon av apoptose i tumorceller som uttrykker toll-lignende reseptor - Google Patents

Induksjon av apoptose i tumorceller som uttrykker toll-lignende reseptor

Info

Publication number
NO20070945L
NO20070945L NO20070945A NO20070945A NO20070945L NO 20070945 L NO20070945 L NO 20070945L NO 20070945 A NO20070945 A NO 20070945A NO 20070945 A NO20070945 A NO 20070945A NO 20070945 L NO20070945 L NO 20070945L
Authority
NO
Norway
Prior art keywords
tumor cells
receptor
toll
apoptosis
induction
Prior art date
Application number
NO20070945A
Other languages
English (en)
Norwegian (no)
Inventor
Serge Lebecque
Toufic Renno
Bruno Salaun
Isabelle Coste-Invernizzi
Marie-Clotilde Rissoan
Original Assignee
Schering Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Corp filed Critical Schering Corp
Publication of NO20070945L publication Critical patent/NO20070945L/no

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7088Compounds having three or more nucleosides or nucleotides
    • A61K31/713Double-stranded nucleic acids or oligonucleotides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01KANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2267/00Animals characterised by purpose
    • A01K2267/03Animal model, e.g. for test or diseases
    • A01K2267/0331Animal model for proliferative diseases

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
NO20070945A 2004-07-20 2007-02-19 Induksjon av apoptose i tumorceller som uttrykker toll-lignende reseptor NO20070945L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US58961604P 2004-07-20 2004-07-20
PCT/US2005/025602 WO2006014653A1 (en) 2004-07-20 2005-07-19 Induction of apoptosis in toll-like receptor expressing tumor cells

Publications (1)

Publication Number Publication Date
NO20070945L true NO20070945L (no) 2007-02-19

Family

ID=35229744

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20070945A NO20070945L (no) 2004-07-20 2007-02-19 Induksjon av apoptose i tumorceller som uttrykker toll-lignende reseptor

Country Status (12)

Country Link
US (2) US20060147456A1 (https=)
EP (1) EP1768699A1 (https=)
JP (1) JP2008507530A (https=)
KR (1) KR20070043795A (https=)
CN (1) CN101018567B (https=)
AT (1) ATE511859T1 (https=)
AU (2) AU2005269733B2 (https=)
CA (1) CA2574176A1 (https=)
MX (1) MX2007000770A (https=)
NO (1) NO20070945L (https=)
RU (1) RU2401661C9 (https=)
WO (1) WO2006014653A1 (https=)

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EP2258712A3 (en) 2002-03-15 2011-05-04 Multicell Immunotherapeutics, Inc. Compositions and Methods to Initiate or Enhance Antibody and Major-histocompatibility Class I or Class II-restricted T Cell Responses by Using Immunomodulatory, Non-coding RNA Motifs
WO2004087877A2 (en) * 2003-03-26 2004-10-14 Astral Inc. Selected rna motifs to include cell death and/or apoptosis
CA2587676A1 (en) * 2004-11-19 2006-05-26 Institut Gustave Roussy Improved treatment of cancer by double-stranded rna
US20120189643A1 (en) * 2004-11-30 2012-07-26 Carton Jill M Toll Like Receptor 3 Antagonists, Methods and Uses
AU2006339445A1 (en) 2006-03-02 2007-09-07 Agency For Science, Technology And Research Methods for cancer therapy and stem cell modulation
US8957035B2 (en) 2006-05-15 2015-02-17 University Of Kentucky Research Foundation Toll like receptor (TLR) stimulation for ocular angiogenesis and macular degeneration
EP1881080A1 (en) * 2006-07-18 2008-01-23 Institut Gustave Roussy Toll like receptor 4 dysfunction and the biological applications thereof
US20080124366A1 (en) * 2006-08-06 2008-05-29 Ohlfest John R Methods and Compositions for Treating Tumors
JP5115921B2 (ja) * 2007-02-28 2013-01-09 株式会社ペルセウスプロテオミクス 腎癌の診断薬および治療薬
AU2008242540A1 (en) * 2007-04-24 2008-10-30 John Wayne Cancer Institute Functional toll-like receptors (TLR) on melanocytes and melanoma cells and uses thereof
CN101909630A (zh) * 2007-11-02 2010-12-08 新加坡科技研究局 预防和治疗肿瘤的方法和化合物
EP2214824A4 (en) * 2007-11-28 2015-08-19 Smart Tube Inc DEVICES, SYSTEMS AND METHODS FOR DETECTING, STIMULATING, STABILIZING AND ANALYZING A BIOLOGICAL SAMPLE
EP2257313A2 (en) 2008-02-21 2010-12-08 University of Kentucky Research Foundation Ultra-small rnas as toll-like receptor-3 antagonists
AU2009239655B2 (en) 2008-04-25 2014-05-22 Innate Pharma Improved TLR3 agonist compositions
EP2316032A1 (en) * 2008-08-20 2011-05-04 INSERM - Institut National de la Santé et de la Recherche Médicale Methods for predicting the response to anti-cancer treatment with an agonist of tlr7 or an agonist of tlr8
GB0820698D0 (en) * 2008-11-12 2008-12-17 Ludwig Inst Cancer Res Uses of immunomodulators
WO2010068680A1 (en) 2008-12-10 2010-06-17 Mount Sinai School Of Medicine Of New York University Thelper cell type 17 lineage-specific adjuvants, compositions and methods
US20120301463A1 (en) 2009-09-30 2012-11-29 President And Fellows Of Harvard College Methods for Modulation of Autophagy Through the Modulation of Autophagy-Enhancing Gene Products
US9090897B2 (en) * 2009-12-18 2015-07-28 Bavarian Nordic A/S Production of IFN-lambda by conventional dendritic cells
KR101250419B1 (ko) * 2010-12-16 2013-04-05 강원대학교산학협력단 Tlr 작동제를 포함하는 유방암 방사선 치료 보조제
CN103889453A (zh) * 2011-07-22 2014-06-25 鲍威尔·卡林斯基 肿瘤选择性趋化因子调节
CN102652802A (zh) * 2012-04-18 2012-09-05 南京中医药大学 癌毒方在制备调控肝癌细胞TLRs/NF-κB信号转导药物中的应用
US9517993B2 (en) 2012-07-29 2016-12-13 The Regents Of The University Of Colorado, A Body Corporate Antagonists of the toll-like receptor 1/2 complex
US10105305B2 (en) * 2014-02-19 2018-10-23 The Johns Hopkins University Compositions and methods for promoting skin regeneration and hair growth
TR201908550T4 (tr) 2014-06-04 2019-07-22 Exicure Inc Profilaktik veya terapötik uygulamalar için lipozomal sferik nükleik asitler tarafından immün modülatörlerin çok değerlikli teslimi.
CN105796594A (zh) * 2016-03-28 2016-07-27 南京大学 一种组合物在制备治疗肿瘤药物中的应用及该组合物的使用方法
CN106191238B (zh) * 2016-07-08 2020-01-10 中国医学科学院基础医学研究所 Tlr3预测肿瘤转移、评估预后和选择防治方案的应用
WO2018039629A2 (en) 2016-08-25 2018-03-01 Northwestern University Micellar spherical nucleic acids from thermoresponsive, traceless templates
WO2018209270A1 (en) 2017-05-11 2018-11-15 Northwestern University Adoptive cell therapy using spherical nucleic acids (snas)
CN108295060A (zh) * 2018-04-08 2018-07-20 王长国 一种tlr7激动剂在增强cik细胞对肿瘤细胞杀伤力方面的应用
WO2020232226A1 (en) 2019-05-16 2020-11-19 The Johns Hopkins University Compositions and methods for skin rejuvenation
CN111117966A (zh) * 2020-03-02 2020-05-08 南通大学 一种利用乳酸的体外细胞培养方法
CN111579538B (zh) * 2020-04-22 2022-12-30 山东第一医科大学(山东省医学科学院) 一种利用凋亡试剂盒检测循环肿瘤细胞的方法
US20240277754A1 (en) * 2021-05-24 2024-08-22 Cha Vaccine Research Institute Co., Ltd Immuno-oncology therapeutic composition using adjuvant including lipopeptides and poly (i:c)
CN115820646A (zh) * 2022-12-20 2023-03-21 武汉光谷中源药业有限公司 一种增强免疫能力的免疫激动剂及其应用

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JP3040121B2 (ja) * 1988-01-12 2000-05-08 ジェネンテク,インコーポレイテッド 増殖因子レセプターの機能を阻害することにより腫瘍細胞を処置する方法
CN1040504A (zh) * 1988-06-22 1990-03-21 Hem研究公司 用双链核糖核酸调节淋巴激活素抗性细胞状态
RU2136278C1 (ru) * 1998-04-07 1999-09-10 Государственный научный центр вирусологии и биотехнологии "Вектор" Противоопухолевое средство
US20040006242A1 (en) * 1999-02-01 2004-01-08 Hawkins Lynn D. Immunomodulatory compounds and method of use thereof
AU2002360243A1 (en) * 2001-07-26 2003-05-06 Tanox, Inc. Agents that activate or inhibit toll-like receptor 9
TW200303759A (en) * 2001-11-27 2003-09-16 Schering Corp Methods for treating cancer
EP1567863A4 (en) * 2002-11-22 2007-10-03 Nuvelo Inc THERAPY AND DIAGNOSTIC PROCEDURES
JP3810731B2 (ja) * 2002-11-29 2006-08-16 独立行政法人科学技術振興機構 哺乳動物のToll様受容体3に結合する新規アダプタータンパク質およびその遺伝子

Also Published As

Publication number Publication date
JP2008507530A (ja) 2008-03-13
WO2006014653A1 (en) 2006-02-09
CA2574176A1 (en) 2006-02-09
EP1768699A1 (en) 2007-04-04
CN101018567B (zh) 2011-07-27
CN101018567A (zh) 2007-08-15
RU2007105987A (ru) 2008-08-27
RU2401661C9 (ru) 2011-01-27
AU2005269733A1 (en) 2006-02-09
RU2401661C2 (ru) 2010-10-20
US20090285779A1 (en) 2009-11-19
ATE511859T1 (de) 2011-06-15
MX2007000770A (es) 2007-03-26
AU2005269733B2 (en) 2008-10-30
KR20070043795A (ko) 2007-04-25
US20060147456A1 (en) 2006-07-06
AU2008249173A1 (en) 2008-12-11

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