MX2010004164A - Terapia de combinacion de un anticuerpo anti-cd20 de tipo ii con un inhibidor de proteasoma. - Google Patents
Terapia de combinacion de un anticuerpo anti-cd20 de tipo ii con un inhibidor de proteasoma.Info
- Publication number
- MX2010004164A MX2010004164A MX2010004164A MX2010004164A MX2010004164A MX 2010004164 A MX2010004164 A MX 2010004164A MX 2010004164 A MX2010004164 A MX 2010004164A MX 2010004164 A MX2010004164 A MX 2010004164A MX 2010004164 A MX2010004164 A MX 2010004164A
- Authority
- MX
- Mexico
- Prior art keywords
- antibody
- type
- proteasome inhibitor
- combination therapy
- combination
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
- A61K39/39558—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against tumor tissues, cells, antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/69—Boron compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2887—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against CD20
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/40—Immunoglobulins specific features characterized by post-translational modification
- C07K2317/41—Glycosylation, sialylation, or fucosylation
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Organic Chemistry (AREA)
- Immunology (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Oncology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Microbiology (AREA)
- Biomedical Technology (AREA)
- Mycology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Hematology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
La presente invención se refiere al uso de un anticuerpo anti-CD20 de tipo II para la fabricación de un medicamento destinado al tratamiento del cáncer, en especial de un cáncer que exprese al CD2O, en combinación con un inhibidor de proteasoma.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP07020820 | 2007-10-24 | ||
PCT/EP2008/008919 WO2009053038A2 (en) | 2007-10-24 | 2008-10-22 | Combination therapy of a type ii anti-cd20 antibody with a proteasome inhibitor |
Publications (1)
Publication Number | Publication Date |
---|---|
MX2010004164A true MX2010004164A (es) | 2010-08-04 |
Family
ID=38973774
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2010004164A MX2010004164A (es) | 2007-10-24 | 2008-10-22 | Terapia de combinacion de un anticuerpo anti-cd20 de tipo ii con un inhibidor de proteasoma. |
Country Status (16)
Country | Link |
---|---|
US (4) | US20090110688A1 (es) |
EP (1) | EP2205318B1 (es) |
JP (1) | JP5469073B2 (es) |
KR (1) | KR101280733B1 (es) |
AR (1) | AR071733A1 (es) |
AU (1) | AU2008315926A1 (es) |
CA (1) | CA2702962C (es) |
CL (1) | CL2008003122A1 (es) |
ES (1) | ES2527775T3 (es) |
IL (1) | IL205025A0 (es) |
MX (1) | MX2010004164A (es) |
PE (1) | PE20090975A1 (es) |
RU (1) | RU2520757C2 (es) |
TW (1) | TW200927762A (es) |
WO (1) | WO2009053038A2 (es) |
ZA (1) | ZA201002575B (es) |
Families Citing this family (22)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
RS58420B1 (sr) | 2003-11-05 | 2019-04-30 | Roche Glycart Ag | Cd20 antitela sa povećanim afinitetom za vezivanje fc receptora i efektornom funkcijom |
AR073295A1 (es) | 2008-09-16 | 2010-10-28 | Genentech Inc | Metodos para tratar la esclerosis multiple progresiva. articulo de fabricacion. |
WO2011018225A1 (en) * | 2009-08-14 | 2011-02-17 | Roche Glycart Ag | Combination therapy of an afucosylated cd20 antibody with fludarabine and/or mitoxantrone |
TWI409079B (zh) * | 2009-08-14 | 2013-09-21 | Roche Glycart Ag | 非典型岩藻醣化cd20抗體與苯達莫斯汀(bendamustine)之組合療法 |
AR078161A1 (es) * | 2009-09-11 | 2011-10-19 | Hoffmann La Roche | Formulaciones farmaceuticas muy concentradas de un anticuerpo anti cd20. uso de la formulacion. metodo de tratamiento. |
EP2498793B1 (en) * | 2009-11-13 | 2019-07-10 | Onyx Therapeutics, Inc. | Oprozomib for use in metastasis suppression |
CA2795544A1 (en) * | 2010-04-27 | 2011-11-03 | Roche Glycart Ag | Combination therapy of an afucosylated cd20 antibody with a mtor inhibitor |
US8809282B2 (en) * | 2010-05-06 | 2014-08-19 | Duke University | Method of reducing titers of antibodies specific for a therapeutic agent |
TW201208703A (en) * | 2010-08-17 | 2012-03-01 | Roche Glycart Ag | Combination therapy of an afucosylated CD20 antibody with an anti-VEGF antibody |
CN103261229A (zh) * | 2010-12-16 | 2013-08-21 | 罗切格利卡特公司 | 无岩藻糖基化cd20抗体与mdm2抑制剂的联合疗法 |
WO2012135528A2 (en) | 2011-03-29 | 2012-10-04 | Texas Tech University System | Galectin-3c combination therapy for human cancer |
CA2834680A1 (en) * | 2011-04-29 | 2012-11-01 | Emory University | Selecting use of proteasome inhibitors based on nf-kb2 sequence |
WO2013112601A1 (en) * | 2012-01-24 | 2013-08-01 | Millennium Pharmaceuticals, Inc. | Methods of treatment of cancer |
CA2862320A1 (en) * | 2012-01-24 | 2013-08-01 | Millennium Pharmaceuticals, Inc. | Method of treatment of nasopharyngeal cancer |
KR102127085B1 (ko) | 2013-03-13 | 2020-06-26 | 제넨테크, 인크. | 항체 제제 |
EP3193932B1 (en) | 2014-09-15 | 2023-04-26 | F. Hoffmann-La Roche AG | Antibody formulations |
EP4252629A3 (en) | 2016-12-07 | 2023-12-27 | Biora Therapeutics, Inc. | Gastrointestinal tract detection methods, devices and systems |
EP3600416B1 (en) | 2017-03-30 | 2023-06-07 | Biora Therapeutics, Inc. | Treatment of a disease of the gastrointestinal tract with an immune modulatory agent released using an ingestible device |
WO2019246312A1 (en) | 2018-06-20 | 2019-12-26 | Progenity, Inc. | Treatment of a disease of the gastrointestinal tract with an immunomodulator |
US20230009902A1 (en) | 2018-06-20 | 2023-01-12 | Progenity, Inc. | Treatment of a disease or condition in a tissue orginating from the endoderm |
KR20210095165A (ko) | 2018-11-19 | 2021-07-30 | 프로제너티, 인크. | 바이오의약품으로 질환을 치료하기 위한 방법 및 디바이스 |
CN115666704A (zh) | 2019-12-13 | 2023-01-31 | 比奥拉治疗股份有限公司 | 用于将治疗剂递送至胃肠道的可摄取装置 |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5736137A (en) * | 1992-11-13 | 1998-04-07 | Idec Pharmaceuticals Corporation | Therapeutic application of chimeric and radiolabeled antibodies to human B lymphocyte restricted differentiation antigen for treatment of B cell lymphoma |
US6083903A (en) * | 1994-10-28 | 2000-07-04 | Leukosite, Inc. | Boronic ester and acid compounds, synthesis and uses |
PT1071700E (pt) * | 1998-04-20 | 2010-04-23 | Glycart Biotechnology Ag | Modificação por glicosilação de anticorpos para melhorar a citotoxicidade celular dependente de anticorpos |
CN1407901A (zh) * | 1999-11-08 | 2003-04-02 | Idec药物公司 | 使用抗cd40l抗体并联合抗cd20抗体和/或化疗剂和放疗治疗b细胞恶性瘤 |
RU2306952C2 (ru) * | 2001-01-31 | 2007-09-27 | Байоджен Айдек Инк. | Лечение в-клеточных злокачественных опухолей с использованием комбинации применений, связанных с антителами, уменьшающими количество b-клеток, и с иммуномодулирующими антителами |
RS58420B1 (sr) * | 2003-11-05 | 2019-04-30 | Roche Glycart Ag | Cd20 antitela sa povećanim afinitetom za vezivanje fc receptora i efektornom funkcijom |
US7589066B2 (en) * | 2005-03-11 | 2009-09-15 | The University Of North Carolina At Chapel Hill | Potent and specific immunoproteasome inhibitors |
KR20080031001A (ko) * | 2005-06-02 | 2008-04-07 | 아스트라제네카 아베 | Cd20에 대한 항체 및 그의 용도 |
BRPI0615397B1 (pt) * | 2005-08-26 | 2023-10-03 | Roche Glycart Ag | Anticorpo anti-cd20, composição farmacêutica que o contém e uso do mesmo |
-
2008
- 2008-09-22 US US12/234,759 patent/US20090110688A1/en not_active Abandoned
- 2008-10-22 AR ARP080104606A patent/AR071733A1/es not_active Application Discontinuation
- 2008-10-22 WO PCT/EP2008/008919 patent/WO2009053038A2/en active Application Filing
- 2008-10-22 JP JP2010530330A patent/JP5469073B2/ja active Active
- 2008-10-22 KR KR1020107009027A patent/KR101280733B1/ko not_active IP Right Cessation
- 2008-10-22 RU RU2010120724/15A patent/RU2520757C2/ru not_active IP Right Cessation
- 2008-10-22 PE PE2008001813A patent/PE20090975A1/es not_active Application Discontinuation
- 2008-10-22 CA CA2702962A patent/CA2702962C/en not_active Expired - Fee Related
- 2008-10-22 AU AU2008315926A patent/AU2008315926A1/en not_active Abandoned
- 2008-10-22 MX MX2010004164A patent/MX2010004164A/es active IP Right Grant
- 2008-10-22 CL CL2008003122A patent/CL2008003122A1/es unknown
- 2008-10-22 ES ES08841724.1T patent/ES2527775T3/es active Active
- 2008-10-22 EP EP08841724.1A patent/EP2205318B1/en active Active
- 2008-10-23 TW TW097140695A patent/TW200927762A/zh unknown
-
2010
- 2010-04-12 IL IL205025A patent/IL205025A0/en unknown
- 2010-04-13 ZA ZA2010/02575A patent/ZA201002575B/en unknown
-
2011
- 2011-03-30 US US13/075,946 patent/US20110200598A1/en not_active Abandoned
-
2012
- 2012-05-04 US US13/464,664 patent/US20120219549A1/en not_active Abandoned
-
2014
- 2014-06-16 US US14/305,996 patent/US20160000912A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
WO2009053038A3 (en) | 2009-06-25 |
WO2009053038A2 (en) | 2009-04-30 |
CL2008003122A1 (es) | 2009-10-16 |
AU2008315926A1 (en) | 2009-04-30 |
CN102083499A (zh) | 2011-06-01 |
RU2010120724A (ru) | 2012-05-20 |
CA2702962A1 (en) | 2009-04-30 |
KR20100068292A (ko) | 2010-06-22 |
US20090110688A1 (en) | 2009-04-30 |
ES2527775T3 (es) | 2015-01-29 |
AR071733A1 (es) | 2010-07-14 |
KR101280733B1 (ko) | 2013-07-02 |
CA2702962C (en) | 2016-10-25 |
EP2205318A2 (en) | 2010-07-14 |
US20120219549A1 (en) | 2012-08-30 |
JP2011500741A (ja) | 2011-01-06 |
JP5469073B2 (ja) | 2014-04-09 |
TW200927762A (en) | 2009-07-01 |
RU2520757C2 (ru) | 2014-06-27 |
IL205025A0 (en) | 2010-11-30 |
ZA201002575B (en) | 2011-04-28 |
US20110200598A1 (en) | 2011-08-18 |
PE20090975A1 (es) | 2009-07-13 |
US20160000912A1 (en) | 2016-01-07 |
EP2205318B1 (en) | 2014-11-19 |
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Legal Events
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FG | Grant or registration |