AU2002360243A1 - Agents that activate or inhibit toll-like receptor 9 - Google Patents

Agents that activate or inhibit toll-like receptor 9

Info

Publication number
AU2002360243A1
AU2002360243A1 AU2002360243A AU2002360243A AU2002360243A1 AU 2002360243 A1 AU2002360243 A1 AU 2002360243A1 AU 2002360243 A AU2002360243 A AU 2002360243A AU 2002360243 A AU2002360243 A AU 2002360243A AU 2002360243 A1 AU2002360243 A1 AU 2002360243A1
Authority
AU
Australia
Prior art keywords
receptor
activate
agents
inhibit toll
toll
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2002360243A
Inventor
Ling-Ling An
Michael S. C. Fung
Herren Wu
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Tanox Inc
Original Assignee
Tanox Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Tanox Inc filed Critical Tanox Inc
Publication of AU2002360243A1 publication Critical patent/AU2002360243A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55516—Proteins; Peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55561—CpG containing adjuvants; Oligonucleotide containing adjuvants

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AU2002360243A 2001-07-26 2002-07-25 Agents that activate or inhibit toll-like receptor 9 Abandoned AU2002360243A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US30806801P 2001-07-26 2001-07-26
US60/308,068 2001-07-26
PCT/US2002/023645 WO2003035695A2 (en) 2001-07-26 2002-07-25 Agents that activate or inhibit toll-like receptor 9

Publications (1)

Publication Number Publication Date
AU2002360243A1 true AU2002360243A1 (en) 2003-05-06

Family

ID=23192407

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2002360243A Abandoned AU2002360243A1 (en) 2001-07-26 2002-07-25 Agents that activate or inhibit toll-like receptor 9

Country Status (4)

Country Link
EP (1) EP1412390A2 (en)
CN (1) CN1642982A (en)
AU (1) AU2002360243A1 (en)
WO (1) WO2003035695A2 (en)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1366077B1 (en) 2000-09-15 2011-05-25 Coley Pharmaceutical GmbH PROCESS FOR HIGH THROUGHPUT SCREENING OF CpG-BASED IMMUNO-AGONIST/ANTAGONIST
WO2003022296A1 (en) 2001-09-07 2003-03-20 The Trustees Of Boston University Method and composition for treating immune complex associated disorders
CA2528774A1 (en) * 2003-06-20 2005-01-27 Coley Pharmaceutical Gmbh Small molecule toll-like receptor (tlr) antagonists
WO2005059517A2 (en) * 2003-12-16 2005-06-30 University Of Massachusetts Toll-like receptor assays
CA2574176A1 (en) * 2004-07-20 2006-02-09 Schering Corporation Induction of apoptosis in toll-like receptor expressing tumor cells
EP1829895A1 (en) * 2006-03-03 2007-09-05 f-star Biotechnologische Forschungs- und Entwicklungsges.m.b.H. Bispecific molecule binding TLR9 and CD32 and comprising a T cell epitope for treatment of allergies
US9636415B2 (en) 2006-03-03 2017-05-02 S-Target Therapeutics Gmbh Bispecific molecule binding TLR9 and CD32 and comprising a T cell epitope for treatment of allergies
CN101240271B (en) * 2006-08-28 2012-08-29 长春华普生物技术有限公司 Toll-like receptor adjustment oligonucleotide and use thereof
CN101134046B (en) * 2006-09-01 2011-10-05 中国医学科学院药物研究所 Application of TLR4 and TLR9 agonist compound in the restraint of tumour metastasis
WO2010030790A2 (en) * 2008-09-10 2010-03-18 The Texas A&M University System Methods and compositions for stimulation of mammalian innate immune resistance to pathogens
EP2411521B1 (en) 2009-03-25 2015-01-14 The Board of Regents of The University of Texas System Compositions for stimulation of mammalian innate immune resistance to pathogens
MX2011012875A (en) 2009-06-05 2012-02-28 13Therapeutics Inc Immunoregulatory peptides and emthods of use.
EP2496944A2 (en) * 2009-11-05 2012-09-12 Novartis AG Biomarkers predictive of progression of fibrosis
CN101712957B (en) * 2009-11-25 2011-11-23 中国人民解放军第三军医大学第一附属医院 Toll-like receptor 9 (TLR9) blocking agent and application thereof
FR2975600B1 (en) 2011-05-24 2013-07-05 Assist Publ Hopitaux De Paris AGENTS FOR THE TREATMENT OF TUMORS
AR095882A1 (en) 2013-04-22 2015-11-18 Hoffmann La Roche ANTIBODY COMBINATION THERAPY AGAINST HUMAN CSF-1R WITH A TLR9 AGONIST
MX2016014926A (en) 2014-05-16 2017-05-09 Ablynx Nv Improved immunoglobulin variable domains.
US11009511B2 (en) 2014-05-16 2021-05-18 Ablynx N.V. Methods for detecting and/or measuring anti-drug antibodies, in particular treatment-emergent anti-drug antibodies
WO2016044839A2 (en) 2014-09-19 2016-03-24 The Board Of Regents Of The University Of Texas System Compositions and methods for treating viral infections through stimulated innate immunity in combination with antiviral compounds
WO2019066571A2 (en) 2017-09-28 2019-04-04 연세대학교 산학협력단 Method for producing myeloid-derived suppressor cells, myeloid-derived suppressor cells produced thereby, and uses thereof
US20210317454A1 (en) * 2020-04-10 2021-10-14 Idera Pharmaceuticals, Inc. Use of a tlr9 agonist in methods for treating covid-19
TWI827057B (en) * 2021-05-18 2023-12-21 中國醫藥大學 Vaccine, use thereof and cancer vaccine cocktail

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0001704D0 (en) * 2000-01-25 2000-03-15 Glaxo Group Ltd Protein
CN1309418C (en) * 2000-06-08 2007-04-11 英特塞尔生物医药研究发展股份公司 Immunostimulatory oligodeoxynucleotides
JP2002034565A (en) * 2000-07-19 2002-02-05 Japan Science & Technology Corp Receptor protein specifically recognizing bacterial dna

Also Published As

Publication number Publication date
EP1412390A2 (en) 2004-04-28
WO2003035695A2 (en) 2003-05-01
WO2003035695A3 (en) 2003-11-13
CN1642982A (en) 2005-07-20

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Legal Events

Date Code Title Description
MK6 Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase