NO2005023I1 - Palonosetron HCI - Google Patents

Palonosetron HCI

Info

Publication number
NO2005023I1
NO2005023I1 NO2005023C NO2005023C NO2005023I1 NO 2005023 I1 NO2005023 I1 NO 2005023I1 NO 2005023 C NO2005023 C NO 2005023C NO 2005023 C NO2005023 C NO 2005023C NO 2005023 I1 NO2005023 I1 NO 2005023I1
Authority
NO
Norway
Prior art keywords
alkyl
amino
alkoxy
halogen
optionally substituted
Prior art date
Application number
NO2005023C
Other languages
English (en)
Other versions
NO2005023I2 (no
Original Assignee
Roche Palo Alto Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=23755479&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=NO2005023(I1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Roche Palo Alto Llc filed Critical Roche Palo Alto Llc
Publication of NO2005023I1 publication Critical patent/NO2005023I1/no
Publication of NO2005023I2 publication Critical patent/NO2005023I2/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
    • C07D451/02—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
    • C07D451/04—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof with hetero atoms directly attached in position 3 of the 8-azabicyclo [3.2.1] octane or in position 7 of the 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
    • C07D451/14—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing 9-azabicyclo [3.3.1] nonane ring systems, e.g. granatane, 2-aza-adamantane; Cyclic acetals thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D453/00—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
    • C07D453/02—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D453/00—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
    • C07D453/06—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing isoquinuclidine ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/06—Peri-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/08—Bridged systems
NO2005023C 1989-11-28 2005-09-21 Palonosetron HCI NO2005023I2 (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US44208289A 1989-11-28 1989-11-28

Publications (2)

Publication Number Publication Date
NO2005023I1 true NO2005023I1 (no) 2005-10-03
NO2005023I2 NO2005023I2 (no) 2009-10-05

Family

ID=23755479

Family Applications (2)

Application Number Title Priority Date Filing Date
NO905120A NO175309C (no) 1989-11-28 1990-11-27 Analogifremgangsmåte for fremstilling av nye, terapeutisk virksomme tricykliske, nitrogenholdige forbindelser
NO2005023C NO2005023I2 (no) 1989-11-28 2005-09-21 Palonosetron HCI

Family Applications Before (1)

Application Number Title Priority Date Filing Date
NO905120A NO175309C (no) 1989-11-28 1990-11-27 Analogifremgangsmåte for fremstilling av nye, terapeutisk virksomme tricykliske, nitrogenholdige forbindelser

Country Status (23)

Country Link
US (1) US5202333A (no)
EP (1) EP0430190B1 (no)
JP (1) JPH0662607B2 (no)
KR (1) KR970007917B1 (no)
AT (1) ATE124698T1 (no)
AU (1) AU642178B2 (no)
BR (1) BR1100680A (no)
CA (1) CA2030718C (no)
DE (2) DE122005000027I2 (no)
DK (1) DK0430190T3 (no)
ES (1) ES2075121T3 (no)
FI (1) FI98367C (no)
HK (1) HK36097A (no)
HU (1) HU218654B (no)
IE (1) IE68434B1 (no)
IL (2) IL96486A (no)
LU (1) LU91162I2 (no)
NL (1) NL300194I2 (no)
NO (2) NO175309C (no)
NZ (1) NZ236225A (no)
PL (3) PL166272B1 (no)
PT (1) PT96001B (no)
ZA (1) ZA909529B (no)

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JP2013510843A (ja) * 2009-11-13 2013-03-28 ヘルシン ヘルスケア ソシエテ アノニム パロノセトロン代謝産物先行出願との関連本出願は２００９年１１月１３日に出願された米国仮出願第６１／２６０，９１６号の優先権を主張する。
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CN106512010A (zh) 2009-11-18 2017-03-22 赫尔辛医疗股份公司 用于治疗中枢介导的恶心及呕吐的组合物及方法
EP2744497B1 (en) 2011-10-18 2016-04-06 Helsinn Healthcare SA Therapeutic combinations of netupitant and palonosetron
CN102688185B (zh) * 2012-06-01 2013-07-10 齐鲁制药(海南)有限公司 一种稳定的帕洛诺司琼注射液及其制备方法
CN105934247A (zh) 2013-12-23 2016-09-07 株式会社三养生物制药 包含帕洛诺司琼的药物组合物
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Also Published As

Publication number Publication date
HK36097A (en) 1997-03-27
IL96486A (en) 1995-03-30
DK0430190T3 (da) 1995-08-21
US5202333A (en) 1993-04-13
PT96001A (pt) 1991-09-30
CA2030718C (en) 1998-05-12
AU6696390A (en) 1991-06-06
HU907660D0 (en) 1991-06-28
FI98367C (fi) 1997-06-10
HUT56368A (en) 1991-08-28
NZ236225A (en) 1992-09-25
NO905120L (no) 1991-05-29
IE68434B1 (en) 1996-06-12
KR910009699A (ko) 1991-06-28
NO905120D0 (no) 1990-11-27
PL287961A1 (en) 1991-12-02
DE69020694T2 (de) 1996-01-18
ES2075121T3 (es) 1995-10-01
NL300194I1 (nl) 2005-07-01
EP0430190B1 (en) 1995-07-05
HU218654B (hu) 2000-10-28
ZA909529B (en) 1992-08-26
JPH03176486A (ja) 1991-07-31
NL300194I2 (nl) 2005-07-01
DE122005000027I2 (de) 2006-03-16
AU642178B2 (en) 1993-10-14
NO175309B (no) 1994-06-20
NO175309C (no) 1994-09-28
PL166267B1 (pl) 1995-04-28
FI905839A (fi) 1991-05-29
DE122005000027I1 (de) 2005-08-04
PT96001B (pt) 1998-01-30
EP0430190A3 (en) 1992-01-22
ATE124698T1 (de) 1995-07-15
FI98367B (fi) 1997-02-28
PL166272B1 (pl) 1995-04-28
NO2005023I2 (no) 2009-10-05
JPH0662607B2 (ja) 1994-08-17
IL96486A0 (en) 1991-08-16
CA2030718A1 (en) 1991-05-29
PL166277B1 (pl) 1995-04-28
KR970007917B1 (ko) 1997-05-17
DE69020694D1 (de) 1995-08-10
FI905839A0 (fi) 1990-11-27
IL110622A (en) 1995-03-30
LU91162I2 (fr) 2005-06-20
IE904269A1 (en) 1991-06-05
BR1100680A (pt) 2000-02-08
EP0430190A2 (en) 1991-06-05

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