ID25477A - Turunan-turunan spiropiperidin - Google Patents
Turunan-turunan spiropiperidinInfo
- Publication number
- ID25477A ID25477A IDW20001358A ID20001358A ID25477A ID 25477 A ID25477 A ID 25477A ID W20001358 A IDW20001358 A ID W20001358A ID 20001358 A ID20001358 A ID 20001358A ID 25477 A ID25477 A ID 25477A
- Authority
- ID
- Indonesia
- Prior art keywords
- substituted
- unsubstituted
- ring
- alkenylene
- alkylene
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
- A61K31/381—Heterocyclic compounds having sulfur as a ring hetero atom having five-membered rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A61K31/428—Thiazoles condensed with carbocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/08—Indoles; Hydrogenated indoles with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to carbon atoms of the hetero ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/60—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/72—Nitrogen atoms
- C07D213/73—Unsubstituted amino or imino radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/60—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings condensed with carbocyclic rings or ring systems
- C07D277/62—Benzothiazoles
- C07D277/68—Benzothiazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D307/38—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D307/54—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
- C07D333/54—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
- C07D333/60—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Pulmonology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Hydrogenated Pyridines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP1111298 | 1998-01-23 | ||
| JP13295998 | 1998-05-15 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ID25477A true ID25477A (id) | 2000-10-05 |
Family
ID=26346503
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IDW20001358A ID25477A (id) | 1998-01-23 | 1999-01-22 | Turunan-turunan spiropiperidin |
Country Status (20)
| Country | Link |
|---|---|
| US (1) | US6511975B1 (id) |
| EP (1) | EP1057827B1 (id) |
| KR (1) | KR100629672B1 (id) |
| CN (1) | CN1165533C (id) |
| AT (1) | ATE249455T1 (id) |
| AU (1) | AU741924B2 (id) |
| BR (1) | BR9907173A (id) |
| CA (1) | CA2318361A1 (id) |
| DE (1) | DE69911176T2 (id) |
| DK (1) | DK1057827T3 (id) |
| ES (1) | ES2203061T3 (id) |
| HU (1) | HUP0100939A3 (id) |
| ID (1) | ID25477A (id) |
| IL (1) | IL137295A (id) |
| MX (1) | MXPA00007240A (id) |
| NO (1) | NO317979B1 (id) |
| NZ (1) | NZ505599A (id) |
| PT (1) | PT1057827E (id) |
| TR (1) | TR200002072T2 (id) |
| WO (1) | WO1999037642A1 (id) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2557537A1 (en) * | 2004-02-25 | 2005-09-01 | Sankyo Company Limited | Sulfonyloxy derivatives |
| TW200536831A (en) | 2004-02-25 | 2005-11-16 | Sankyo Co | Indanol derivatives |
| ES2350647T3 (es) * | 2005-03-08 | 2011-01-25 | Janssen Pharmaceutica Nv | Derivados de diaza-espiro-[4.4]-nonano como antagonistas de neuroquininas (nk1). |
| US8224647B2 (en) | 2005-10-03 | 2012-07-17 | Nuance Communications, Inc. | Text-to-speech user's voice cooperative server for instant messaging clients |
| DK2291080T3 (en) | 2008-05-14 | 2015-12-07 | Scripps Research Inst | Novel modulator of sphingosinphosphatreceptorer |
| SG174389A1 (en) | 2009-03-17 | 2011-10-28 | Daiichi Sankyo Co Ltd | Amide derivative |
| KR101771755B1 (ko) * | 2009-11-13 | 2017-08-25 | 셀진 인터내셔널 Ii 에스에이알엘 | 선택적 헤테로시클릭 스핑고신 1 포스페이트 수용체 조절자 |
| WO2011060389A1 (en) | 2009-11-13 | 2011-05-19 | Receptos, Inc. | Sphingosine 1 phosphate receptor modulators and methods of chiral synthesis |
| RS61829B1 (sr) * | 2009-11-13 | 2021-06-30 | Receptos Llc | Selektivni modulatori receptora sfingozin 1 fosfata i metode hiralne sinteze |
| EP2484674A1 (en) * | 2011-02-02 | 2012-08-08 | Rottapharm S.P.A. | Spiro aminic compounds with NK1 antagonist activity |
| JP6129159B2 (ja) | 2011-05-13 | 2017-05-17 | レセプトス エルエルシー | 選択的複素環式スフィンゴシン１−リン酸受容体モジュレーター |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0681571B1 (en) * | 1993-01-28 | 1998-07-29 | Merck & Co. Inc. | Spiro-substituted azacycles as tachykinin receptor antagonists |
| RU2135494C1 (ru) * | 1995-12-01 | 1999-08-27 | Санкио Компани Лимитед | Гетероциклические соединения и композиция на их основе, проявляющая антагонистическое действие в отношении рецепторов тахикинина |
| JP3192631B2 (ja) * | 1997-05-28 | 2001-07-30 | 三共株式会社 | 飽和複素環化合物からなる医薬 |
| TR199902943T2 (xx) | 1997-05-30 | 2000-05-22 | Sankyo Company Limited | Optik bak�mdan aktif s�lfoksit t�revinin tuzlar�. |
-
1999
- 1999-01-22 KR KR1020007007983A patent/KR100629672B1/ko not_active Expired - Fee Related
- 1999-01-22 CN CNB998044369A patent/CN1165533C/zh not_active Expired - Fee Related
- 1999-01-22 ES ES99901134T patent/ES2203061T3/es not_active Expired - Lifetime
- 1999-01-22 AT AT99901134T patent/ATE249455T1/de not_active IP Right Cessation
- 1999-01-22 WO PCT/JP1999/000226 patent/WO1999037642A1/ja not_active Ceased
- 1999-01-22 BR BR9907173-8A patent/BR9907173A/pt not_active Application Discontinuation
- 1999-01-22 CA CA002318361A patent/CA2318361A1/en not_active Abandoned
- 1999-01-22 DK DK99901134T patent/DK1057827T3/da active
- 1999-01-22 TR TR2000/02072T patent/TR200002072T2/xx unknown
- 1999-01-22 MX MXPA00007240A patent/MXPA00007240A/es not_active IP Right Cessation
- 1999-01-22 IL IL13729599A patent/IL137295A/en active IP Right Grant
- 1999-01-22 NZ NZ505599A patent/NZ505599A/xx unknown
- 1999-01-22 AU AU20739/99A patent/AU741924B2/en not_active Ceased
- 1999-01-22 ID IDW20001358A patent/ID25477A/id unknown
- 1999-01-22 DE DE69911176T patent/DE69911176T2/de not_active Expired - Fee Related
- 1999-01-22 EP EP99901134A patent/EP1057827B1/en not_active Expired - Lifetime
- 1999-01-22 PT PT99901134T patent/PT1057827E/pt unknown
- 1999-01-22 HU HU0100939A patent/HUP0100939A3/hu unknown
-
2000
- 2000-07-13 US US09/616,092 patent/US6511975B1/en not_active Expired - Fee Related
- 2000-07-14 NO NO20003630A patent/NO317979B1/no unknown
Also Published As
| Publication number | Publication date |
|---|---|
| HUP0100939A2 (hu) | 2002-05-29 |
| NO20003630D0 (no) | 2000-07-14 |
| TR200002072T2 (tr) | 2000-12-21 |
| NO20003630L (no) | 2000-09-20 |
| KR20010034280A (ko) | 2001-04-25 |
| MXPA00007240A (es) | 2002-05-08 |
| BR9907173A (pt) | 2000-10-10 |
| WO1999037642A1 (fr) | 1999-07-29 |
| DE69911176D1 (de) | 2003-10-16 |
| NO317979B1 (no) | 2005-01-17 |
| AU741924B2 (en) | 2001-12-13 |
| US6511975B1 (en) | 2003-01-28 |
| PT1057827E (pt) | 2003-11-28 |
| DE69911176T2 (de) | 2004-06-24 |
| EP1057827A1 (en) | 2000-12-06 |
| KR100629672B1 (ko) | 2006-09-29 |
| HK1032780A1 (en) | 2001-08-03 |
| NZ505599A (en) | 2003-06-30 |
| ES2203061T3 (es) | 2004-04-01 |
| EP1057827B1 (en) | 2003-09-10 |
| ATE249455T1 (de) | 2003-09-15 |
| CN1165533C (zh) | 2004-09-08 |
| HUP0100939A3 (en) | 2002-06-28 |
| DK1057827T3 (da) | 2004-01-26 |
| IL137295A (en) | 2005-12-18 |
| EP1057827A4 (en) | 2001-11-21 |
| IL137295A0 (en) | 2001-07-24 |
| AU2073999A (en) | 1999-08-09 |
| CA2318361A1 (en) | 1999-07-29 |
| CN1294588A (zh) | 2001-05-09 |
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