AR069625A1 - Base libre de palonosetron y procedimiento para su preparacion - Google Patents

Base libre de palonosetron y procedimiento para su preparacion

Info

Publication number
AR069625A1
AR069625A1 ARP080105354A ARP080105354A AR069625A1 AR 069625 A1 AR069625 A1 AR 069625A1 AR P080105354 A ARP080105354 A AR P080105354A AR P080105354 A ARP080105354 A AR P080105354A AR 069625 A1 AR069625 A1 AR 069625A1
Authority
AR
Argentina
Prior art keywords
preparation
free base
procedure
palonosetron
palonosetron free
Prior art date
Application number
ARP080105354A
Other languages
English (en)
Inventor
Mubeen Ahmed Khan
Mahendra Raghunath Patil
Prashant Kundlik Yadav
Original Assignee
Glenmark Generics Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glenmark Generics Ltd filed Critical Glenmark Generics Ltd
Publication of AR069625A1 publication Critical patent/AR069625A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D453/00—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
    • C07D453/02—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Otolaryngology (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Hospice & Palliative Care (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

La presente provee una novedosa base libre de palonosetron (3aS)-2-[(S)-1-azabiciclo[2.2.2]oct-3-il]-2,3,3a,4,5,6-hexahidro-1oxo-1H benz [cfe]isoquinolina en una forma amorfa y forma-G cristalina y procedimientos para su preparacion. La presente también provee un procedimiento para la preparacion de palonosetron hidrocloruro a partir de la nueva base libre de palonosetron en una forma amorfa y/o en forma-G cristalina. Antiemético u antinauseoso.
ARP080105354A 2007-12-13 2008-12-10 Base libre de palonosetron y procedimiento para su preparacion AR069625A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IN2448MU2007 2007-12-13
US6247908P 2008-01-26 2008-01-26

Publications (1)

Publication Number Publication Date
AR069625A1 true AR069625A1 (es) 2010-02-03

Family

ID=40853550

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP080105354A AR069625A1 (es) 2007-12-13 2008-12-10 Base libre de palonosetron y procedimiento para su preparacion

Country Status (4)

Country Link
US (1) US8304544B2 (es)
EP (1) EP2231658A4 (es)
AR (1) AR069625A1 (es)
WO (1) WO2009087669A2 (es)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103159765B (zh) * 2011-12-15 2015-06-24 北京嘉林药业股份有限公司 一种适于产业化的吲地司琼纯化方法
CN102652739A (zh) * 2011-12-17 2012-09-05 东莞达信生物技术有限公司 一种帕洛诺司琼口腔膜剂及其制备方法
US8691335B2 (en) * 2012-02-08 2014-04-08 Empire Technology Development, Llc Coating a substance with graphene

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0662607B2 (ja) 1989-11-28 1994-08-17 シンテックス（ユー・エス・エイ） インコーポレイテッド 新規三環式化合物
US5567818A (en) 1994-07-08 1996-10-22 Syntex (U.S.A.) Inc. Processes for preparing 2-(1-azabicyclo[2.2.2]oct-3-yl)-1H-benz[de] isoquinolin-1-one derivatives and intermediates useful therein
US5510486A (en) * 1994-07-26 1996-04-23 Syntex (U.S.A.) Inc. Process for preparing 2-(1-azabicyclo 2.2.2!oct-3-yl)-2,3,3A,4,5,6-hexahydro-1H-benz de!isoquinolin-1-one
WO2008146283A2 (en) * 2007-05-29 2008-12-04 Chemagis Ltd. Novel palonosetron salts and processes for preparation and purification thereof
WO2009010987A1 (en) * 2007-07-19 2009-01-22 Natco Pharma Limited An improved process for the preparation of pure palonosetron hydrochloride
WO2009136405A1 (en) * 2008-05-05 2009-11-12 Natco Pharma Limited High purity palonosetron base and its solid state characteristics

Also Published As

Publication number Publication date
US20100292267A1 (en) 2010-11-18
US8304544B2 (en) 2012-11-06
WO2009087669A2 (en) 2009-07-16
WO2009087669A3 (en) 2009-10-15
EP2231658A4 (en) 2010-11-24
EP2231658A2 (en) 2010-09-29

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Legal Events

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