NO20031839L - Fremgangsmåte for rensing og gjenvinning av proteiner - Google Patents

Fremgangsmåte for rensing og gjenvinning av proteiner

Info

Publication number
NO20031839L
NO20031839L NO20031839A NO20031839A NO20031839L NO 20031839 L NO20031839 L NO 20031839L NO 20031839 A NO20031839 A NO 20031839A NO 20031839 A NO20031839 A NO 20031839A NO 20031839 L NO20031839 L NO 20031839L
Authority
NO
Norway
Prior art keywords
ifn
purification
recovery
renaturation
hcl
Prior art date
Application number
NO20031839A
Other languages
English (en)
Other versions
NO326288B1 (no
NO20031839D0 (no
Inventor
Sid Wolfe
Irinn Esikova
Susan Babuka
Bret A Shirley
Dennis Fordham
Original Assignee
Chiron Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chiron Corp filed Critical Chiron Corp
Publication of NO20031839D0 publication Critical patent/NO20031839D0/no
Publication of NO20031839L publication Critical patent/NO20031839L/no
Publication of NO326288B1 publication Critical patent/NO326288B1/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/555—Interferons [IFN]
    • C07K14/565—IFN-beta

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicinal Preparation (AREA)
NO20031839A 2000-10-27 2003-04-24 Fremgangsmate for fremstilling av en sammensetning omfattende monomer interferon-β NO326288B1 (no)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US24396500P 2000-10-27 2000-10-27
US28260701P 2001-04-09 2001-04-09
US33037501P 2001-10-18 2001-10-18
US10/035,420 US7544354B2 (en) 2000-10-27 2001-10-25 Methods of protein purification and recovery
PCT/US2001/051038 WO2002034791A2 (en) 2000-10-27 2001-10-26 Methods of purification and recovery of interferon-beta

Publications (3)

Publication Number Publication Date
NO20031839D0 NO20031839D0 (no) 2003-04-24
NO20031839L true NO20031839L (no) 2003-05-28
NO326288B1 NO326288B1 (no) 2008-11-03

Family

ID=27488301

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20031839A NO326288B1 (no) 2000-10-27 2003-04-24 Fremgangsmate for fremstilling av en sammensetning omfattende monomer interferon-β

Country Status (16)

Country Link
US (3) US7544354B2 (no)
EP (1) EP1366060B1 (no)
JP (1) JP3946139B2 (no)
CN (1) CN100493601C (no)
AT (1) ATE383368T1 (no)
AU (1) AU2002234161B2 (no)
BG (1) BG66119B1 (no)
CA (1) CA2427088C (no)
CZ (1) CZ301360B6 (no)
DE (1) DE60132366T2 (no)
ES (1) ES2299528T3 (no)
IL (1) IL155577A0 (no)
NO (1) NO326288B1 (no)
PL (1) PL206428B1 (no)
PT (1) PT1366060E (no)
WO (1) WO2002034791A2 (no)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7544354B2 (en) * 2000-10-27 2009-06-09 Novartis Vaccines And Diagnostics Methods of protein purification and recovery
US20050079579A1 (en) * 2001-02-28 2005-04-14 Guangwen Wei Uses of spatial configuration to modulate protein function
CN1245215C (zh) * 2001-02-28 2006-03-15 四川省生物工程研究中心 重组高效复合干扰素用作乙型肝炎表面抗原和e抗原抑制剂
US20060035327A1 (en) * 2001-02-28 2006-02-16 Guangwen Wei Recombinant super-compound interferon and uses thereof
US6887462B2 (en) 2001-04-09 2005-05-03 Chiron Corporation HSA-free formulations of interferon-beta
US20050029194A1 (en) * 2003-08-07 2005-02-10 Hall David Bruce Method for removal of guanidine compound from aqueous media
US7585647B2 (en) * 2003-08-28 2009-09-08 Guangwen Wei Nucleic acid encoding recombinant interferon
AU2006257286B2 (en) * 2005-03-09 2012-08-16 Superlab Far East Limited Uses of recombinant super-compound interferons
CA2602951A1 (en) * 2005-03-23 2006-09-28 Bio-Rad Laboratories, Inc. Diverse chemical libraries bound to small particles with paramagnetic properties
US20090247421A1 (en) * 2005-03-23 2009-10-01 Egisto Boschetti Diverse chemical libraries bound to small particles with paramagnetic properties
MX2008001396A (es) * 2005-07-29 2008-04-16 Novartis Ag Metodo y sistema para plegado in vitro de proteinas.
JP2007126391A (ja) * 2005-11-02 2007-05-24 Sanyo Chem Ind Ltd タンパク質のリフォールディング剤
US7858661B2 (en) 2005-08-16 2010-12-28 Sanyo Chemical Industries, Ltd. Protein refolding agent and refolding method
JP4786303B2 (ja) * 2005-11-02 2011-10-05 三洋化成工業株式会社 タンパク質のリフォールディング剤
JP5274795B2 (ja) * 2006-07-27 2013-08-28 三洋化成工業株式会社 タンパク質のリフォールディング方法
JP2010525821A (ja) 2007-05-02 2010-07-29 アンブルックス，インコーポレイテッド 修飾ＩＦＮβポリペプチドおよびこれらの使用
US8273561B2 (en) * 2007-10-05 2012-09-25 Nuron Biotech, Inc. High pressure treatment of aggregated interferons
KR101113495B1 (ko) 2008-01-23 2012-02-29 한미홀딩스 주식회사 인간 인터페론 베타의 정제방법
GB0821010D0 (en) * 2008-11-17 2008-12-24 Univ Warwick Plant development control composition
CN101885767B (zh) * 2010-06-13 2013-03-13 深圳科兴生物工程有限公司 一种取代单克隆抗体亲和层析的分离纯化重组人干扰素α1b的方法

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5702699A (en) 1982-09-23 1997-12-30 Cetus Corporation Process for the recovery of lipophilic proteins
US5643566A (en) 1982-09-23 1997-07-01 Cetus Corporation Formulation processes for lipophilic proteins
US4462940A (en) 1982-09-23 1984-07-31 Cetus Corporation Process for the recovery of human β-interferon-like polypeptides
US4992271A (en) 1982-09-23 1991-02-12 Cetus Corporation Formulation for lipophilic IL-2 proteins
US4816440A (en) 1985-09-26 1989-03-28 Cetus Corporation Stable formulation of biologically active proteins for parenteral injection
CA1294215C (en) 1986-10-27 1992-01-14 Ze'ev Shaked Pharmaceutical compositions of recombinant beta-interferon and formulation processes
US5183746A (en) * 1986-10-27 1993-02-02 Schering Aktiengesellschaft Formulation processes for pharmaceutical compositions of recombinant β-
US4894330A (en) 1986-12-23 1990-01-16 Cetus Corporation Purification of recombinant beta-interferon incorporating RP-HPLC
US5162507A (en) 1987-05-11 1992-11-10 Cetus Corporation Process for recovering purified, oxidized, renatured recombinant interleukin-2 from microorganisms
US4931543A (en) 1987-05-11 1990-06-05 Cetus Corporation Process for recovering microbially produced interleukin-2
US5004605A (en) * 1987-12-10 1991-04-02 Cetus Corporation Low pH pharmaceutical compositions of recombinant β-interferon
CA1340586C (en) 1988-09-23 1999-06-08 Cetus Corporation Process for recovering microbially produced interferon-beta
KR930006706B1 (ko) 1991-04-29 1993-07-23 주식회사 럭키 인간 인터페론 베타의 정제방법
DE4407325B4 (de) * 1994-03-04 2006-06-29 Basf Ag Verfahren zur Herstellung von 3-Aminomethyl-3,5,5-trimethylcyclohexylamin
MX9605717A (es) 1994-05-18 1998-05-31 Inhale Therapeutic Syst Metodos y composiciones para la formulacion de polvo seco de interferones.
US5814485A (en) * 1995-06-06 1998-09-29 Chiron Corporation Production of interferon-β (IFN-β) in E. coli
BR9606270A (pt) 1996-12-18 1998-09-22 Univ Minas Gerais Processo para a produção da proteína do interferon beta-cis humano recombinante e proteína de interferon beta-cis humano recombinante
US20030190307A1 (en) * 1996-12-24 2003-10-09 Biogen, Inc. Stable liquid interferon formulations
US7544354B2 (en) * 2000-10-27 2009-06-09 Novartis Vaccines And Diagnostics Methods of protein purification and recovery
US6887462B2 (en) 2001-04-09 2005-05-03 Chiron Corporation HSA-free formulations of interferon-beta

Also Published As

Publication number Publication date
CZ20031157A3 (en) 2004-03-17
BG107844A (bg) 2004-07-30
EP1366060A2 (en) 2003-12-03
CN100493601C (zh) 2009-06-03
IL155577A0 (en) 2003-11-23
JP2004512343A (ja) 2004-04-22
JP3946139B2 (ja) 2007-07-18
PT1366060E (pt) 2008-03-17
NO326288B1 (no) 2008-11-03
CA2427088A1 (en) 2002-05-02
ATE383368T1 (de) 2008-01-15
ES2299528T3 (es) 2008-06-01
CZ301360B6 (cs) 2010-01-27
WO2002034791A2 (en) 2002-05-02
US20090123424A1 (en) 2009-05-14
DE60132366T2 (de) 2009-01-29
US20020137895A1 (en) 2002-09-26
PL365896A1 (en) 2005-01-10
US20040115169A1 (en) 2004-06-17
US7544354B2 (en) 2009-06-09
US8388942B2 (en) 2013-03-05
BG66119B1 (bg) 2011-05-31
AU2002234161B2 (en) 2006-10-19
PL206428B1 (pl) 2010-08-31
NO20031839D0 (no) 2003-04-24
CA2427088C (en) 2011-06-21
WO2002034791A3 (en) 2003-10-09
DE60132366D1 (de) 2008-02-21
CN1479627A (zh) 2004-03-03
EP1366060B1 (en) 2008-01-09

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