YU64192A - Analozi insulina - Google Patents

Analozi insulina

Info

Publication number
YU64192A
YU64192A YU64192A YU64192A YU64192A YU 64192 A YU64192 A YU 64192A YU 64192 A YU64192 A YU 64192A YU 64192 A YU64192 A YU 64192A YU 64192 A YU64192 A YU 64192A
Authority
YU
Yugoslavia
Prior art keywords
insulin analogs
insulin
sequence
human insulin
analogs
Prior art date
Application number
YU64192A
Other languages
English (en)
Inventor
N.D. Brems
E.R. Chance
Hb. Frank
Original Assignee
Eli Lilly And Company
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eli Lilly And Company filed Critical Eli Lilly And Company
Publication of YU64192A publication Critical patent/YU64192A/sh

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/62—Insulins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Abstract

Opisani su analozi insulina i postupak za njihovo dobijanje kao i formulacije koje sadrže analoge insulina zajedno sa farmaceutski prihvatljivim ekscipijentima, razblaživačima i nosačima, pri čemu postupak obuhvata modifikovanje analoga humanog insulina sa odredjenim izmenama aminokiselina na odred-jenim mestima u B-nizu i A-nizu nativnog humanog insulina i uklanjanje tripeptida ili tetrapeptida sa karboksilnog kraja B-niza nativnog humanog insulina. Analozi insulina prema ovom pronalasku u obliku formulacija koje sadrže pomenute analoge insulina se upotrebljavaju za lečenje hiperglikemije i pokazuju značajne prednosti u odnosu na humani insulin.
YU64192A 1991-06-21 1992-06-19 Analozi insulina YU64192A (sh)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US71857491A 1991-06-21 1991-06-21

Publications (1)

Publication Number Publication Date
YU64192A true YU64192A (sh) 1994-06-10

Family

ID=24886590

Family Applications (1)

Application Number Title Priority Date Filing Date
YU64192A YU64192A (sh) 1991-06-21 1992-06-19 Analozi insulina

Country Status (17)

Country Link
EP (1) EP0519750A3 (sh)
JP (1) JPH05271283A (sh)
CN (1) CN1069737A (sh)
AU (1) AU1837792A (sh)
BR (1) BR9202322A (sh)
CA (1) CA2071382A1 (sh)
CZ (1) CZ186492A3 (sh)
FI (1) FI922882A (sh)
HU (1) HUT61581A (sh)
IE (1) IE921997A1 (sh)
IL (1) IL102240A0 (sh)
MX (1) MX9202987A (sh)
NO (1) NO922376L (sh)
NZ (1) NZ243229A (sh)
TW (1) TW222643B (sh)
YU (1) YU64192A (sh)
ZA (1) ZA924448B (sh)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1994014461A1 (en) * 1992-12-18 1994-07-07 Eli Lilly And Company Insulin analogs
US20020111461A1 (en) 1999-05-21 2002-08-15 Todd C. Somers Low molecular weight peptidomimetic growth hormone secretagogues
ES2266187T3 (es) 2000-03-24 2007-03-01 Genentech, Inc. Uso de la insulina para el tratamiento de trastornos del cartilago.
EP1862174A1 (en) * 2005-03-02 2007-12-05 Ajinomoto Co., Inc. Inhibitor for insulin polymer formation

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PH25772A (en) * 1985-08-30 1991-10-18 Novo Industri As Insulin analogues, process for their preparation
AU612141B2 (en) * 1987-02-25 1991-07-04 Novo Nordisk A/S Novel insulin derivatives
US4992418A (en) * 1987-07-17 1991-02-12 Mount Sinai School Of Medicine Superactive human insulin analogue-[10-Aspartic Acid-B]Human Insulin
PT93057B (pt) * 1989-02-09 1995-12-29 Lilly Co Eli Processo para a preparacao de analogos da insulina

Also Published As

Publication number Publication date
IE921997A1 (en) 1992-12-30
ZA924448B (en) 1993-12-17
BR9202322A (pt) 1993-01-19
EP0519750A2 (en) 1992-12-23
NO922376D0 (no) 1992-06-17
CA2071382A1 (en) 1992-12-22
JPH05271283A (ja) 1993-10-19
IL102240A0 (en) 1993-01-14
FI922882A0 (fi) 1992-06-18
MX9202987A (es) 1993-01-01
AU1837792A (en) 1992-12-24
TW222643B (sh) 1994-04-21
NZ243229A (en) 1994-09-27
CZ186492A3 (en) 1993-01-13
FI922882A (fi) 1992-12-22
EP0519750A3 (en) 1993-06-23
HUT61581A (en) 1993-01-28
HU9202048D0 (en) 1992-09-28
NO922376L (no) 1992-12-22
CN1069737A (zh) 1993-03-10

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