NO1998020I1 - Raltitrexed - Google Patents

Raltitrexed

Info

Publication number
NO1998020I1
NO1998020I1 NO1998020C NO1998020C NO1998020I1 NO 1998020 I1 NO1998020 I1 NO 1998020I1 NO 1998020 C NO1998020 C NO 1998020C NO 1998020 C NO1998020 C NO 1998020C NO 1998020 I1 NO1998020 I1 NO 1998020I1
Authority
NO
Norway
Prior art keywords
raltitrexed
Prior art date
Application number
NO1998020C
Other languages
English (en)
Original Assignee
Zeneca Ltd
National Res Development Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zeneca Ltd, National Res Development Corp filed Critical Zeneca Ltd
Publication of NO1998020I1 publication Critical patent/NO1998020I1/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/70Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
    • C07D239/72Quinazolines; Hydrogenated quinazolines
    • C07D239/86Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in position 4
    • C07D239/88Oxygen atoms
    • C07D239/90Oxygen atoms with acyclic radicals attached in position 2 or 3
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/70Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
    • C07D239/72Quinazolines; Hydrogenated quinazolines
    • C07D239/95Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in positions 2 and 4
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/70Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
    • C07D239/72Quinazolines; Hydrogenated quinazolines
    • C07D239/95Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in positions 2 and 4
    • C07D239/96Two oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/12Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
NO1998020C 1986-03-27 1998-09-08 Raltitrexed NO1998020I1 (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB868607683A GB8607683D0 (en) 1986-03-27 1986-03-27 Anti-tumor agents

Publications (1)

Publication Number Publication Date
NO1998020I1 true NO1998020I1 (no) 1998-09-28

Family

ID=10595358

Family Applications (2)

Application Number Title Priority Date Filing Date
NO871266A NO173545C (no) 1986-03-27 1987-03-26 Analogifremgangsmaate for fremstilling av terapeutisk aktive kinazolinderivater
NO1998020C NO1998020I1 (no) 1986-03-27 1998-09-08 Raltitrexed

Family Applications Before (1)

Application Number Title Priority Date Filing Date
NO871266A NO173545C (no) 1986-03-27 1987-03-26 Analogifremgangsmaate for fremstilling av terapeutisk aktive kinazolinderivater

Country Status (22)

Country Link
US (2) US4992550A (no)
EP (1) EP0239362B1 (no)
JP (1) JPH0657699B2 (no)
AR (1) AR244213A1 (no)
AT (1) ATE70057T1 (no)
AU (1) AU592628B2 (no)
CA (1) CA1285943C (no)
DE (1) DE3774909D1 (no)
DK (1) DK166621B1 (no)
ES (1) ES2038170T3 (no)
FI (1) FI89912C (no)
GB (2) GB8607683D0 (no)
GR (1) GR3003282T3 (no)
HK (1) HK8594A (no)
HU (1) HU197317B (no)
IE (1) IE60302B1 (no)
IL (1) IL81924A (no)
LU (1) LU88797I2 (no)
NL (1) NL970024I2 (no)
NO (2) NO173545C (no)
PT (1) PT84571B (no)
ZA (1) ZA871998B (no)

Families Citing this family (112)

* Cited by examiner, † Cited by third party
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GB8727737D0 (en) * 1987-11-26 1987-12-31 Ici Plc Antitumour agents
US4940713A (en) * 1988-04-15 1990-07-10 Burroughs Wellcome Co. Substituted glutamic acids
US5019577A (en) * 1988-04-15 1991-05-28 Burroughs Welcome Co. Novel compounds and use
GB8809978D0 (en) * 1988-04-27 1988-06-02 Ici Plc Anti-tumour agents
EP0365763A1 (en) * 1988-09-30 1990-05-02 Agouron Pharmaceuticals, Inc. Antiproliferative cyclic compounds
US5252573A (en) * 1988-12-15 1993-10-12 Imperial Chemical Industries Plc Anti-tumor agents
GB8829296D0 (en) * 1988-12-15 1989-01-25 Ici Plc Anti-tumour compounds
US5286726A (en) * 1990-04-12 1994-02-15 The Regents Of The University Of Michigan Difluoroglutamic acid conjugates with folates and anti-folates for the treatment of neoplastic diseases
ZA913730B (en) * 1990-05-30 1992-02-26 Ici Plc Anti-tumor compounds
GB9013615D0 (en) * 1990-06-19 1990-08-08 Wellcome Found Pharmaceutical compounds
US5290780A (en) * 1991-01-30 1994-03-01 American Cyanamid Co. Angiotensin II receptor blocking 2,3,6 substituted quinazolinones
GB9105771D0 (en) * 1991-03-19 1991-05-01 Cancer Res Inst Royal Anti-cancer compounds
NZ243082A (en) 1991-06-28 1995-02-24 Ici Plc 4-anilino-quinazoline derivatives; pharmaceutical compositions, preparatory processes, and use thereof
DE69216509T2 (de) * 1991-08-12 1997-05-28 Takeda Chemical Industries Ltd Kondensierte Pyrimidinderivate, ihre Herstellung und ihre Verwendung als Antitumormittel
US5145854A (en) * 1991-11-27 1992-09-08 Nair Madhavan G 1-formyl-5,8,10-trideazafolates
GB9205320D0 (en) * 1992-03-11 1992-04-22 Ici Plc Anti-tumour compounds
GB9205907D0 (en) * 1992-03-18 1992-04-29 Cancer Res Inst Royal Anti-cancer compounds
ES2049659B1 (es) * 1992-10-08 1994-10-16 Ici Plc Una composicion farmaceutica a base de derivados de quinazolina con actividad anti-cancerigena.
GB9223352D0 (en) * 1992-11-06 1992-12-23 Ici Plc Tricyclic compounds
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GB1021196A (en) * 1964-02-20 1966-03-02 Parke Davis & Co Novel amino acids and means for producing the same
DE3069468D1 (en) * 1979-12-19 1984-11-22 Nat Res Dev Quinazoline derivatives, processes for their preparation, compositions containing them and their use as anti-cancer agents
GB8513754D0 (en) * 1985-05-31 1985-07-03 Jones T R Anti-cancer quinazoline derivatives

Also Published As

Publication number Publication date
HU197317B (en) 1989-03-28
FI871139A (fi) 1987-09-28
IL81924A (en) 1991-07-18
GB8706948D0 (en) 1987-04-29
US4992550A (en) 1991-02-12
PT84571B (pt) 1989-11-30
JPH01125373A (ja) 1989-05-17
DK155087D0 (da) 1987-03-26
NO871266D0 (no) 1987-03-26
GR3003282T3 (en) 1993-02-17
FI89912C (fi) 1993-12-10
EP0239362A2 (en) 1987-09-30
PT84571A (en) 1987-04-01
NO173545B (no) 1993-09-20
LU88797I2 (fr) 1996-11-05
DE3774909D1 (de) 1992-01-16
ZA871998B (en) 1987-11-25
IE60302B1 (en) 1994-06-29
HUT43835A (en) 1987-12-28
NL970024I2 (nl) 1997-10-01
AR244213A1 (es) 1993-10-29
AU7047287A (en) 1987-10-01
ATE70057T1 (de) 1991-12-15
FI871139A0 (fi) 1987-03-16
NL970024I1 (nl) 1997-09-01
DK166621B1 (da) 1993-06-21
ES2038170T3 (es) 1993-07-16
US5081124A (en) 1992-01-14
CA1285943C (en) 1991-07-09
DK155087A (da) 1987-09-28
AU592628B2 (en) 1990-01-18
GB2188319B (en) 1989-12-13
HK8594A (en) 1994-02-04
FI89912B (fi) 1993-08-31
EP0239362B1 (en) 1991-12-04
NO871266L (no) 1987-09-28
GB8607683D0 (en) 1986-04-30
JPH0657699B2 (ja) 1994-08-03
GB2188319A (en) 1987-09-30
IE870699L (en) 1987-09-27
EP0239362A3 (en) 1989-07-05
NO173545C (no) 1993-12-29

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