SG11202113215UA - Methods of treating virally associated cancers with histone deacetylase inhibitors - Google Patents

Methods of treating virally associated cancers with histone deacetylase inhibitors

Info

Publication number
SG11202113215UA
SG11202113215UA SG11202113215UA SG11202113215UA SG11202113215UA SG 11202113215U A SG11202113215U A SG 11202113215UA SG 11202113215U A SG11202113215U A SG 11202113215UA SG 11202113215U A SG11202113215U A SG 11202113215UA SG 11202113215U A SG11202113215U A SG 11202113215UA
Authority
SG
Singapore
Prior art keywords
methods
histone deacetylase
deacetylase inhibitors
associated cancers
virally associated
Prior art date
Application number
SG11202113215UA
Inventor
Robert Mcrae
Gail Brown
Xiaohu Deng
David Slack
Marshelle Warren
Richard Trauger
Original Assignee
Viracta Subsidiary Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Viracta Subsidiary Inc filed Critical Viracta Subsidiary Inc
Priority claimed from PCT/US2020/034951 external-priority patent/WO2020243326A1/en
Publication of SG11202113215UA publication Critical patent/SG11202113215UA/en

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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
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    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
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    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A61K31/167—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
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    • A61K31/325—Carbamic acids; Thiocarbamic acids; Anhydrides or salts thereof
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    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
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    • A61K31/4045—Indole-alkylamines; Amides thereof, e.g. serotonin, melatonin
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    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
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    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A61K31/52—Purines, e.g. adenine
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    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
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    • A61K9/2022—Organic macromolecular compounds
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    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
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    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/286—Polysaccharides, e.g. gums; Cyclodextrin
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/4709—Non-condensed quinolines and containing further heterocyclic rings
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    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
SG11202113215UA 2019-05-31 2020-05-28 Methods of treating virally associated cancers with histone deacetylase inhibitors SG11202113215UA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201962855454P 2019-05-31 2019-05-31
PCT/US2020/034951 WO2020243326A1 (en) 2019-05-31 2020-05-28 Methods of treating virally associated cancers with histone deacetylase inhibitors

Publications (1)

Publication Number Publication Date
SG11202113215UA true SG11202113215UA (en) 2021-12-30

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ID=73550979

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11202113215UA SG11202113215UA (en) 2019-05-31 2020-05-28 Methods of treating virally associated cancers with histone deacetylase inhibitors

Country Status (11)

Country Link
US (2) US20220226322A1 (en)
EP (1) EP3976198A4 (en)
JP (1) JP2022536256A (en)
KR (1) KR20220034736A (en)
CN (1) CN114206447A (en)
AU (1) AU2020283590A1 (en)
BR (1) BR112021024073A2 (en)
CA (1) CA3142142A1 (en)
IL (1) IL288425A (en)
MX (1) MX2021014639A (en)
SG (1) SG11202113215UA (en)

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