FI871139A - Antitumoermedel. - Google Patents

Antitumoermedel. Download PDF

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Publication number
FI871139A
FI871139A FI871139A FI871139A FI871139A FI 871139 A FI871139 A FI 871139A FI 871139 A FI871139 A FI 871139A FI 871139 A FI871139 A FI 871139A FI 871139 A FI871139 A FI 871139A
Authority
FI
Finland
Prior art keywords
antitumoermedel
Prior art date
Application number
FI871139A
Other languages
English (en)
Other versions
FI89912C (fi
FI89912B (fi
FI871139A0 (fi
Inventor
Leslie Richard Hughes
Original Assignee
Ici Plc
Nat Res Dev
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ici Plc, Nat Res Dev filed Critical Ici Plc
Publication of FI871139A0 publication Critical patent/FI871139A0/fi
Publication of FI871139A publication Critical patent/FI871139A/fi
Application granted granted Critical
Publication of FI89912B publication Critical patent/FI89912B/fi
Publication of FI89912C publication Critical patent/FI89912C/fi

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/70Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
    • C07D239/72Quinazolines; Hydrogenated quinazolines
    • C07D239/86Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in position 4
    • C07D239/88Oxygen atoms
    • C07D239/90Oxygen atoms with acyclic radicals attached in position 2 or 3
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/70Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
    • C07D239/72Quinazolines; Hydrogenated quinazolines
    • C07D239/95Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in positions 2 and 4
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/70Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
    • C07D239/72Quinazolines; Hydrogenated quinazolines
    • C07D239/95Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in positions 2 and 4
    • C07D239/96Two oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/12Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
FI871139A 1986-03-27 1987-03-16 Foerfarande foer framstaellning av terapeutiskt anvaendbara kinazolinderivat FI89912C (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB868607683A GB8607683D0 (en) 1986-03-27 1986-03-27 Anti-tumor agents
GB8607683 1986-03-27

Publications (4)

Publication Number Publication Date
FI871139A0 FI871139A0 (fi) 1987-03-16
FI871139A true FI871139A (fi) 1987-09-28
FI89912B FI89912B (fi) 1993-08-31
FI89912C FI89912C (fi) 1993-12-10

Family

ID=10595358

Family Applications (1)

Application Number Title Priority Date Filing Date
FI871139A FI89912C (fi) 1986-03-27 1987-03-16 Foerfarande foer framstaellning av terapeutiskt anvaendbara kinazolinderivat

Country Status (22)

Country Link
US (2) US4992550A (fi)
EP (1) EP0239362B1 (fi)
JP (1) JPH0657699B2 (fi)
AR (1) AR244213A1 (fi)
AT (1) ATE70057T1 (fi)
AU (1) AU592628B2 (fi)
CA (1) CA1285943C (fi)
DE (1) DE3774909D1 (fi)
DK (1) DK166621B1 (fi)
ES (1) ES2038170T3 (fi)
FI (1) FI89912C (fi)
GB (2) GB8607683D0 (fi)
GR (1) GR3003282T3 (fi)
HK (1) HK8594A (fi)
HU (1) HU197317B (fi)
IE (1) IE60302B1 (fi)
IL (1) IL81924A (fi)
LU (1) LU88797I2 (fi)
NL (1) NL970024I2 (fi)
NO (2) NO173545C (fi)
PT (1) PT84571B (fi)
ZA (1) ZA871998B (fi)

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US5286726A (en) * 1990-04-12 1994-02-15 The Regents Of The University Of Michigan Difluoroglutamic acid conjugates with folates and anti-folates for the treatment of neoplastic diseases
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Also Published As

Publication number Publication date
HK8594A (en) 1994-02-04
FI89912C (fi) 1993-12-10
GB8607683D0 (en) 1986-04-30
GB8706948D0 (en) 1987-04-29
HU197317B (en) 1989-03-28
IE60302B1 (en) 1994-06-29
IE870699L (en) 1987-09-27
EP0239362B1 (en) 1991-12-04
NO871266L (no) 1987-09-28
NO1998020I1 (no) 1998-09-28
GB2188319B (en) 1989-12-13
EP0239362A3 (en) 1989-07-05
NL970024I1 (nl) 1997-09-01
GB2188319A (en) 1987-09-30
GR3003282T3 (en) 1993-02-17
CA1285943C (en) 1991-07-09
US5081124A (en) 1992-01-14
HUT43835A (en) 1987-12-28
DK155087D0 (da) 1987-03-26
FI89912B (fi) 1993-08-31
NO173545C (no) 1993-12-29
JPH0657699B2 (ja) 1994-08-03
PT84571A (en) 1987-04-01
ATE70057T1 (de) 1991-12-15
DK166621B1 (da) 1993-06-21
FI871139A0 (fi) 1987-03-16
IL81924A (en) 1991-07-18
AU592628B2 (en) 1990-01-18
DE3774909D1 (de) 1992-01-16
LU88797I2 (fr) 1996-11-05
EP0239362A2 (en) 1987-09-30
DK155087A (da) 1987-09-28
ES2038170T3 (es) 1993-07-16
NO871266D0 (no) 1987-03-26
JPH01125373A (ja) 1989-05-17
AR244213A1 (es) 1993-10-29
ZA871998B (en) 1987-11-25
AU7047287A (en) 1987-10-01
US4992550A (en) 1991-02-12
NL970024I2 (nl) 1997-10-01
PT84571B (pt) 1989-11-30
NO173545B (no) 1993-09-20

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