NO175429C - Analogifremgangsmåte ved fremstilling av terapeutisk aktive 16-dehydro-vitamin-D3-derivater - Google Patents

Analogifremgangsmåte ved fremstilling av terapeutisk aktive 16-dehydro-vitamin-D3-derivater

Info

Publication number
NO175429C
NO175429C NO890239A NO890239A NO175429C NO 175429 C NO175429 C NO 175429C NO 890239 A NO890239 A NO 890239A NO 890239 A NO890239 A NO 890239A NO 175429 C NO175429 C NO 175429C
Authority
NO
Norway
Prior art keywords
dehydro
vitamin
derivatives
therapeutically active
analogous process
Prior art date
Application number
NO890239A
Other languages
English (en)
Norwegian (no)
Other versions
NO890239D0 (no
NO175429B (no
NO890239L (no
Inventor
Enrico Giuseppe Baggiolini
Bernard Michael Hennessy
Shian-Jan Shiuey
Gary Arthur Truitt
Milan Radoje Uskokovic
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of NO890239D0 publication Critical patent/NO890239D0/no
Publication of NO890239L publication Critical patent/NO890239L/no
Publication of NO175429B publication Critical patent/NO175429B/no
Publication of NO175429C publication Critical patent/NO175429C/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C401/00—Irradiation products of cholesterol or its derivatives; Vitamin D derivatives, 9,10-seco cyclopenta[a]phenanthrene or analogues obtained by chemical preparation without irradiation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/02—Nutrients, e.g. vitamins, minerals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02—Silicon compounds
    • C07F7/08—Compounds having one or more C—Si linkages
    • C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
    • C07F7/1804—Compounds having Si-O-C linkages

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Nutrition Science (AREA)
  • Diabetes (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
NO890239A 1988-01-20 1989-01-19 Analogifremgangsmåte ved fremstilling av terapeutisk aktive 16-dehydro-vitamin-D3-derivater NO175429C (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US14593288A 1988-01-20 1988-01-20

Publications (4)

Publication Number Publication Date
NO890239D0 NO890239D0 (no) 1989-01-19
NO890239L NO890239L (no) 1989-07-21
NO175429B NO175429B (no) 1994-07-04
NO175429C true NO175429C (no) 1994-10-12

Family

ID=22515181

Family Applications (1)

Application Number Title Priority Date Filing Date
NO890239A NO175429C (no) 1988-01-20 1989-01-19 Analogifremgangsmåte ved fremstilling av terapeutisk aktive 16-dehydro-vitamin-D3-derivater

Country Status (23)

Country Link
EP (1) EP0325279B1 (pt)
JP (1) JPH0764806B2 (pt)
KR (1) KR960009119B1 (pt)
AR (1) AR247551A1 (pt)
AT (1) ATE74350T1 (pt)
AU (1) AU622139B2 (pt)
BG (1) BG60530B2 (pt)
CA (1) CA1337529C (pt)
DE (1) DE58901056D1 (pt)
DK (1) DK169945B1 (pt)
ES (1) ES2033467T3 (pt)
FI (1) FI90764C (pt)
GR (1) GR3004786T3 (pt)
HU (1) HU201007B (pt)
IE (1) IE60921B1 (pt)
IL (1) IL88989A (pt)
MC (1) MC1998A1 (pt)
NO (1) NO175429C (pt)
NZ (1) NZ227641A (pt)
PH (1) PH25605A (pt)
PT (1) PT89486B (pt)
YU (1) YU47298B (pt)
ZA (1) ZA8923B (pt)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4804502A (en) * 1988-01-20 1989-02-14 Hoffmann-La Roche Inc. Vitamin D compounds
ATE99942T1 (de) * 1989-05-18 1994-01-15 Hoffmann La Roche Dehydrocholecalciferolderivate.
AU650751B2 (en) * 1991-05-28 1994-06-30 Wisconsin Alumni Research Foundation Novel synthesis of 19-nor vitamin D compounds
ATE141914T1 (de) * 1992-05-20 1996-09-15 Hoffmann La Roche Fluorierte analoge vitamins d3
CA2096105A1 (en) * 1992-10-07 1994-04-08 Enrico Giuseppe Baggiolini (Deceased) Vitamin d3 fluorinated analogs
US5753638A (en) * 1992-10-07 1998-05-19 Hoffmann-La Roche Inc. Method of treating hyperproliferative skin disease with Vitamin D3 fluorinated analogs
TW267161B (pt) * 1992-11-20 1996-01-01 Hoffmann La Roche
US5401733A (en) * 1993-10-01 1995-03-28 Hoffmann-La Roche Inc. Stable and active metabolites of 1,25-dihydroxy-16-ene-cholecalciferol
US5428029A (en) * 1993-11-24 1995-06-27 Hoffmann-La Roche Inc. Vitamin D3 fluorinated analogs
TW403735B (en) * 1995-11-22 2000-09-01 Hoffmann La Roche 25-hydroxy-16-ene-26, 27-bishomo-cholecalciferol
AU708679B2 (en) * 1996-03-21 1999-08-12 F. Hoffmann-La Roche Ag 1,25-dihydroxy-16,22,23-trisdehydro-cholecalciferol derivatives
US5939408A (en) * 1996-05-23 1999-08-17 Hoffman-La Roche Inc. Vitamin D3 analogs
SG70009A1 (en) * 1996-05-23 2000-01-25 Hoffmann La Roche Vitamin d3 analogs
ES2196476T3 (es) * 1997-05-02 2003-12-16 Duphar Int Res Un metodo de preparar compuestos de 16-deshidro-vitamina d.
US6331642B1 (en) * 1999-07-12 2001-12-18 Hoffmann-La Roche Inc. Vitamin D3 analogs
JP4795023B2 (ja) * 2004-02-03 2011-10-19 中外製薬株式会社 ビタミンｄ化合物及びそれらの合成中間体の合成方法
WO2006113990A2 (en) * 2005-04-25 2006-11-02 Cytochroma Inc. LOW-CALCEMIC 16,23-DIENE 25-OXIME ANALOGS OF 1α ,25-DIHYDROXY VITAMIN D3
CN101287705A (zh) * 2005-08-18 2008-10-15 拜奥艾克塞尔股份公司 1α-氟-25-羟基-16-23E-二烯-26,27-双高-20-表-胆骨化醇的合成

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2812741C2 (de) * 1977-03-24 1987-03-12 Wisconsin Alumni Research Foundation, Madison, Wis. Vitamin D↓3↓-Derivate, Verfahren und Zwischenprodukte zu deren Herstellung und diese enthaltende Arzneimittel
FR2426044A2 (fr) * 1978-05-19 1979-12-14 Wisconsin Research Foundation Derives de la vitamine d3 ayant une activite anti-vitamine d
US4360471A (en) * 1981-12-11 1982-11-23 Wisconsin Alumni Research Foundation 23-Dehydro-25-hydroxyvitamin D3
US4508651A (en) * 1983-03-21 1985-04-02 Hoffmann-La Roche Inc. Synthesis of 1α,25-dihydroxyergocalciferol
US4505906A (en) * 1984-01-30 1985-03-19 Wisconsin Alumni Research Foundation Hydroxyvitamin D2 isomers
US4612308A (en) * 1984-11-29 1986-09-16 Hoffmann-La Roche Inc. 25,26-Dehydro-1α,23(S,R)-dihydroxycholecalciferol and its epimers
US4898855A (en) * 1987-09-14 1990-02-06 Hoffman-La Roche Inc. Deuterated analogs of 1,25-dihydroxycholecalciferol
US4804502A (en) * 1988-01-20 1989-02-14 Hoffmann-La Roche Inc. Vitamin D compounds
ATE99942T1 (de) * 1989-05-18 1994-01-15 Hoffmann La Roche Dehydrocholecalciferolderivate.

Also Published As

Publication number Publication date
DK19789A (da) 1989-07-21
GR3004786T3 (pt) 1993-04-28
EP0325279A1 (de) 1989-07-26
HUT49317A (en) 1989-09-28
KR890011838A (ko) 1989-08-22
AU2864489A (en) 1989-07-20
ES2033467T3 (es) 1993-03-16
FI90764B (fi) 1993-12-15
ZA8923B (en) 1989-09-27
NO890239D0 (no) 1989-01-19
JPH029861A (ja) 1990-01-12
IL88989A0 (en) 1989-08-15
FI90764C (fi) 1994-03-25
CA1337529C (en) 1995-11-07
YU11789A (en) 1991-04-30
AU622139B2 (en) 1992-04-02
PT89486B (pt) 1993-12-31
PH25605A (en) 1991-08-08
YU47298B (sh) 1995-01-31
NZ227641A (en) 1991-06-25
PT89486A (pt) 1989-10-04
EP0325279B1 (de) 1992-04-01
ATE74350T1 (de) 1992-04-15
DE58901056D1 (de) 1992-05-07
JPH0764806B2 (ja) 1995-07-12
FI890283A (fi) 1989-07-21
HU201007B (en) 1990-09-28
FI890283A0 (fi) 1989-01-19
DK19789D0 (da) 1989-01-17
AR247551A1 (es) 1995-01-31
BG60530B2 (bg) 1995-07-28
MC1998A1 (fr) 1990-01-26
NO175429B (no) 1994-07-04
IL88989A (en) 1993-08-18
DK169945B1 (da) 1995-04-10
IE60921B1 (en) 1994-09-07
KR960009119B1 (en) 1996-07-13
IE890157L (en) 1989-07-20
NO890239L (no) 1989-07-21

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