NO176100C - Analogifremgangsmåte for fremstilling av terapeutisk aktive oksodihydropyridyl- og oksodihydropyridazinylkromanderivater - Google Patents

Analogifremgangsmåte for fremstilling av terapeutisk aktive oksodihydropyridyl- og oksodihydropyridazinylkromanderivater

Info

Publication number
NO176100C
NO176100C NO903275A NO903275A NO176100C NO 176100 C NO176100 C NO 176100C NO 903275 A NO903275 A NO 903275A NO 903275 A NO903275 A NO 903275A NO 176100 C NO176100 C NO 176100C
Authority
NO
Norway
Prior art keywords
chromomene
oxodihydropyridyl
oxodihydropyridazinyl
derivatives
therapeutically active
Prior art date
Application number
NO903275A
Other languages
English (en)
Other versions
NO903275D0 (no
NO176100B (no
NO903275L (no
Inventor
Rolf Gericke
Manfred Baumgarth
Ingeborg Lues
Rolf Bergmann
Jacques De Peyer
Original Assignee
Merck Patent Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Patent Gmbh filed Critical Merck Patent Gmbh
Publication of NO903275D0 publication Critical patent/NO903275D0/no
Publication of NO903275L publication Critical patent/NO903275L/no
Publication of NO176100B publication Critical patent/NO176100B/no
Publication of NO176100C publication Critical patent/NO176100C/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/04Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/02Drugs for disorders of the nervous system for peripheral neuropathies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/08Vasodilators for multiple indications
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D311/00Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/22Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
NO903275A 1989-07-24 1990-07-23 Analogifremgangsmåte for fremstilling av terapeutisk aktive oksodihydropyridyl- og oksodihydropyridazinylkromanderivater NO176100C (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE3924417A DE3924417A1 (de) 1989-07-24 1989-07-24 Chromanderivate

Publications (4)

Publication Number Publication Date
NO903275D0 NO903275D0 (no) 1990-07-23
NO903275L NO903275L (no) 1991-01-25
NO176100B NO176100B (no) 1994-10-24
NO176100C true NO176100C (no) 1995-02-01

Family

ID=6385695

Family Applications (1)

Application Number Title Priority Date Filing Date
NO903275A NO176100C (no) 1989-07-24 1990-07-23 Analogifremgangsmåte for fremstilling av terapeutisk aktive oksodihydropyridyl- og oksodihydropyridazinylkromanderivater

Country Status (20)

Country Link
US (1) US5143924A (no)
EP (1) EP0410208B1 (no)
JP (1) JPH0358983A (no)
KR (1) KR910002845A (no)
AR (1) AR245938A1 (no)
AT (1) ATE107640T1 (no)
AU (1) AU623544B2 (no)
CA (1) CA2021684A1 (no)
DE (2) DE3924417A1 (no)
DK (1) DK0410208T3 (no)
ES (1) ES2055830T3 (no)
FI (1) FI95250C (no)
HU (1) HU206707B (no)
IE (1) IE63917B1 (no)
IL (1) IL95167A (no)
NO (1) NO176100C (no)
NZ (1) NZ234609A (no)
PT (1) PT94792B (no)
TW (1) TW210337B (no)
ZA (1) ZA905773B (no)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5387587A (en) * 1986-12-23 1995-02-07 Merck Patent Gesellschaft Mit Beschrankter Haftung Chroman derivatives
US5284838A (en) * 1987-06-23 1994-02-08 Elf Sanofi Use of 2,2-dimethylchroman-3-ol derivatives in the treatment of asthma
DE3922392A1 (de) * 1989-07-07 1991-01-17 Merck Patent Gmbh Chromanderivate
CA2070243A1 (en) * 1991-06-14 1992-12-15 Akira Shiozawa Chroman derivatives
US5250547A (en) * 1991-08-29 1993-10-05 Syntex (U.S.A.) Inc. Benzopyran derivatives
US5837702A (en) * 1993-10-07 1998-11-17 Bristol-Myers Squibb Co. 4-arylamino-benzopyran and related compounds
EP0677519A4 (en) * 1993-11-10 1996-04-03 Japan Tobacco Inc CHROMAN DERIVATIVE AND THERAPEUTIC USE THEREOF.
US5482942A (en) * 1994-06-28 1996-01-09 American Home Products Corporation (3,4-dioxocyclobuten-1-yl)chromene, indene, and dihydronaphthalenone derivatives as smooth muscle relaxants
US5470861A (en) * 1994-08-04 1995-11-28 Hoffmann-La Roche Inc. Method of promoting hair growth
US5612323A (en) * 1995-06-07 1997-03-18 Bristol-Myers Squibb Company Phosphinic ester substituted benzopyran derivatives
US5869478A (en) * 1995-06-07 1999-02-09 Bristol-Myers Squibb Company Sulfonamido substituted benzopyran derivatives
US5612370A (en) * 1995-06-07 1997-03-18 Bristol-Myers Squibb Company Phenylglycine and phenylalaninen amido benzopyran derivatives
US5629429A (en) * 1995-06-07 1997-05-13 Bristol-Myers Squibb Company Process for preparing 4-arylamino-benzopyran and related compounds

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1770171C3 (de) * 1967-04-14 1979-08-30 Beecham Group Ltd., Brentford, Mddlesex (Grossbritannien) 2,2-Dimethyl-7-alkyl-4-(4-pyridyl)-2H-chromen-5-ole, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Arzneipräparate
US3973023A (en) * 1972-01-26 1976-08-03 Beecham Group Limited Anti-hypertensive polycyclic compounds for treating hypertension
GB1417745A (en) * 1973-07-07 1975-12-17 Beecham Group Ltd Chromene compounds
US3947462A (en) * 1974-05-22 1976-03-30 Abbott Laboratories 2,4,7-substituted 5-hydroxy benzopyrans and esters
DE2745305A1 (de) * 1977-10-07 1979-04-19 Bayer Ag Insektizide und akarizide mittel
US4486428A (en) * 1982-03-16 1984-12-04 Pfizer Inc. Bicyclic benzo fused compounds
ATE56007T1 (de) * 1984-06-22 1990-09-15 Beecham Group Plc Wirksame benzopyranverbindungen.
GB8521857D0 (en) * 1985-09-03 1985-10-09 Beecham Group Plc Active compounds
DE3726261A1 (de) * 1986-12-23 1988-07-07 Merck Patent Gmbh Chromanderivate
DE3835011A1 (de) * 1988-10-14 1990-04-19 Merck Patent Gmbh Chromanderivate
CH674984A5 (no) * 1987-05-16 1990-08-15 Sandoz Ag
FI90343C (fi) * 1987-06-23 1994-01-25 Merck Patent Gmbh Menetelmä korkeaa verenpainetta alentavien ja rytmihäiriöitä vastustavien trans-2,2-dimetyylikroman-3-olijohdannaisten valmistamiseksi
US4971982A (en) * 1987-07-06 1990-11-20 Hoffmann-La Roche Inc. Benzopyran derivatives
JPH0753725B2 (ja) * 1987-10-08 1995-06-07 富山化学工業株式会社 4h―1―ベンゾピラン―4―オン誘導体およびその塩、それらの製造法並びにそれらを含有する抗炎症剤
FR2621587B1 (fr) * 1987-10-12 1990-02-09 Sanofi Sa Derives du dimethyl-2,2 chromene, procede pour leur preparation et composition pharmaceutiques les contenant
DE3811017A1 (de) * 1988-03-31 1989-10-19 Hoechst Ag Ungesaettigte n-benzopyranyllactame
AU628331B2 (en) * 1988-05-06 1992-09-17 Merck Patent Gesellschaft Mit Beschrankter Haftung Chroman derivatives
DE3918041A1 (de) * 1989-06-02 1990-12-06 Merck Patent Gmbh Chromanderivate

Also Published As

Publication number Publication date
ES2055830T3 (es) 1994-09-01
HUT59130A (en) 1992-04-28
IE902676A1 (en) 1991-02-27
EP0410208A1 (de) 1991-01-30
NZ234609A (en) 1991-04-26
CA2021684A1 (en) 1991-01-25
NO903275D0 (no) 1990-07-23
NO176100B (no) 1994-10-24
EP0410208B1 (de) 1994-06-22
US5143924A (en) 1992-09-01
DK0410208T3 (da) 1994-07-25
AR245938A1 (es) 1994-03-30
ATE107640T1 (de) 1994-07-15
IE63917B1 (en) 1995-06-14
DE3924417A1 (de) 1991-01-31
DE59006189D1 (de) 1994-07-28
PT94792B (pt) 1997-03-31
AU5975190A (en) 1991-01-24
ZA905773B (en) 1991-05-29
FI95250B (fi) 1995-09-29
KR910002845A (ko) 1991-02-26
PT94792A (pt) 1991-03-20
AU623544B2 (en) 1992-05-14
HU904594D0 (en) 1990-12-28
FI903704A0 (fi) 1990-07-23
IL95167A (en) 1995-11-27
IL95167A0 (en) 1991-06-10
FI95250C (fi) 1996-01-10
HU206707B (en) 1992-12-28
TW210337B (no) 1993-08-01
NO903275L (no) 1991-01-25
JPH0358983A (ja) 1991-03-14

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