PT89486A - Processo para a preparacao de derivados 16-de-hidro de vitamina d3 e de composicoes farmaceuticas que os contem - Google Patents

Processo para a preparacao de derivados 16-de-hidro de vitamina d3 e de composicoes farmaceuticas que os contem

Info

Publication number
PT89486A
PT89486A PT89486A PT8948689A PT89486A PT 89486 A PT89486 A PT 89486A PT 89486 A PT89486 A PT 89486A PT 8948689 A PT8948689 A PT 8948689A PT 89486 A PT89486 A PT 89486A
Authority
PT
Portugal
Prior art keywords
vitamin
contain
preparation
pharmaceutical compositions
dehydro derivatives
Prior art date
Application number
PT89486A
Other languages
English (en)
Other versions
PT89486B (pt
Inventor
Enrico Giuseppe Baggiolini
Bernard Michael Hennessy
Shian-Jan Shiuey
Gary Arthur Truitt
Milan Radoje Uskokovic
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of PT89486A publication Critical patent/PT89486A/pt
Publication of PT89486B publication Critical patent/PT89486B/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C401/00—Irradiation products of cholesterol or its derivatives; Vitamin D derivatives, 9,10-seco cyclopenta[a]phenanthrene or analogues obtained by chemical preparation without irradiation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/02—Nutrients, e.g. vitamins, minerals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02—Silicon compounds
    • C07F7/08—Compounds having one or more C—Si linkages
    • C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
    • C07F7/1804—Compounds having Si-O-C linkages

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nutrition Science (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
PT89486A 1988-01-20 1989-01-19 Processo para a preparacao de derivados 16-de-hidro de vitamina d3 e de composicoes farmaceuticas que os contem PT89486B (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US14593288A 1988-01-20 1988-01-20

Publications (2)

Publication Number Publication Date
PT89486A true PT89486A (pt) 1989-10-04
PT89486B PT89486B (pt) 1993-12-31

Family

ID=22515181

Family Applications (1)

Application Number Title Priority Date Filing Date
PT89486A PT89486B (pt) 1988-01-20 1989-01-19 Processo para a preparacao de derivados 16-de-hidro de vitamina d3 e de composicoes farmaceuticas que os contem

Country Status (23)

Country Link
EP (1) EP0325279B1 (pt)
JP (1) JPH0764806B2 (pt)
KR (1) KR960009119B1 (pt)
AR (1) AR247551A1 (pt)
AT (1) ATE74350T1 (pt)
AU (1) AU622139B2 (pt)
BG (1) BG60530B2 (pt)
CA (1) CA1337529C (pt)
DE (1) DE58901056D1 (pt)
DK (1) DK169945B1 (pt)
ES (1) ES2033467T3 (pt)
FI (1) FI90764C (pt)
GR (1) GR3004786T3 (pt)
HU (1) HU201007B (pt)
IE (1) IE60921B1 (pt)
IL (1) IL88989A (pt)
MC (1) MC1998A1 (pt)
NO (1) NO175429C (pt)
NZ (1) NZ227641A (pt)
PH (1) PH25605A (pt)
PT (1) PT89486B (pt)
YU (1) YU47298B (pt)
ZA (1) ZA8923B (pt)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4804502A (en) * 1988-01-20 1989-02-14 Hoffmann-La Roche Inc. Vitamin D compounds
EP0398217B1 (de) * 1989-05-18 1994-01-12 F. Hoffmann-La Roche Ag Dehydrocholecalciferolderivate
AU650751B2 (en) * 1991-05-28 1994-06-30 Wisconsin Alumni Research Foundation Novel synthesis of 19-nor vitamin D compounds
DK0580968T3 (da) * 1992-05-20 1996-10-14 Hoffmann La Roche Fluorerede analoger af vitamin D3
CA2096105A1 (en) * 1992-10-07 1994-04-08 Enrico Giuseppe Baggiolini (Deceased) Vitamin d3 fluorinated analogs
US5753638A (en) * 1992-10-07 1998-05-19 Hoffmann-La Roche Inc. Method of treating hyperproliferative skin disease with Vitamin D3 fluorinated analogs
TW267161B (pt) * 1992-11-20 1996-01-01 Hoffmann La Roche
US5401733A (en) * 1993-10-01 1995-03-28 Hoffmann-La Roche Inc. Stable and active metabolites of 1,25-dihydroxy-16-ene-cholecalciferol
US5428029A (en) * 1993-11-24 1995-06-27 Hoffmann-La Roche Inc. Vitamin D3 fluorinated analogs
TW403735B (en) * 1995-11-22 2000-09-01 Hoffmann La Roche 25-hydroxy-16-ene-26, 27-bishomo-cholecalciferol
AU708679B2 (en) * 1996-03-21 1999-08-12 F. Hoffmann-La Roche Ag 1,25-dihydroxy-16,22,23-trisdehydro-cholecalciferol derivatives
SG70009A1 (en) * 1996-05-23 2000-01-25 Hoffmann La Roche Vitamin d3 analogs
US5939408A (en) * 1996-05-23 1999-08-17 Hoffman-La Roche Inc. Vitamin D3 analogs
JPH10316652A (ja) * 1997-05-02 1998-12-02 Duphar Internatl Res Bv １６−デヒドロビタミンｄ化合物の製造方法
US6331642B1 (en) * 1999-07-12 2001-12-18 Hoffmann-La Roche Inc. Vitamin D3 analogs
JP4795023B2 (ja) * 2004-02-03 2011-10-19 中外製薬株式会社 ビタミンｄ化合物及びそれらの合成中間体の合成方法
US8906888B2 (en) * 2005-04-25 2014-12-09 Cytochroma Inc. Low-calcemic 16,23-diene 25-oxime analogs of 1α,25-dihydroxy vitamin D3
WO2007022433A2 (en) * 2005-08-18 2007-02-22 Bioxell S.P.A. SYNTHESIS OF 1α-FLUORO-25-HYDROXY-16-23E-DIENE-26,27-BISHOMO-20-EPI-CHOLECALCIFEROL

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2812741A1 (de) * 1977-03-24 1978-10-05 Wisconsin Alumni Res Found Vitamin d tief 3 -derivate, verfahren zu deren herstellung und diese enthaltende arzneimittel
FR2426044A2 (fr) * 1978-05-19 1979-12-14 Wisconsin Research Foundation Derives de la vitamine d3 ayant une activite anti-vitamine d
US4360471A (en) * 1981-12-11 1982-11-23 Wisconsin Alumni Research Foundation 23-Dehydro-25-hydroxyvitamin D3
US4508651A (en) * 1983-03-21 1985-04-02 Hoffmann-La Roche Inc. Synthesis of 1α,25-dihydroxyergocalciferol
US4505906A (en) * 1984-01-30 1985-03-19 Wisconsin Alumni Research Foundation Hydroxyvitamin D2 isomers
US4612308A (en) * 1984-11-29 1986-09-16 Hoffmann-La Roche Inc. 25,26-Dehydro-1α,23(S,R)-dihydroxycholecalciferol and its epimers
US4898855A (en) * 1987-09-14 1990-02-06 Hoffman-La Roche Inc. Deuterated analogs of 1,25-dihydroxycholecalciferol
US4804502A (en) * 1988-01-20 1989-02-14 Hoffmann-La Roche Inc. Vitamin D compounds
EP0398217B1 (de) * 1989-05-18 1994-01-12 F. Hoffmann-La Roche Ag Dehydrocholecalciferolderivate

Also Published As

Publication number Publication date
FI90764C (fi) 1994-03-25
GR3004786T3 (pt) 1993-04-28
EP0325279B1 (de) 1992-04-01
DE58901056D1 (de) 1992-05-07
AU2864489A (en) 1989-07-20
HUT49317A (en) 1989-09-28
JPH029861A (ja) 1990-01-12
NO890239D0 (no) 1989-01-19
PH25605A (en) 1991-08-08
NO175429B (no) 1994-07-04
FI890283A0 (fi) 1989-01-19
DK19789D0 (da) 1989-01-17
IL88989A (en) 1993-08-18
DK19789A (da) 1989-07-21
NO890239L (no) 1989-07-21
HU201007B (en) 1990-09-28
IE890157L (en) 1989-07-20
ZA8923B (en) 1989-09-27
IL88989A0 (en) 1989-08-15
KR890011838A (ko) 1989-08-22
DK169945B1 (da) 1995-04-10
ATE74350T1 (de) 1992-04-15
NO175429C (no) 1994-10-12
AU622139B2 (en) 1992-04-02
IE60921B1 (en) 1994-09-07
YU11789A (en) 1991-04-30
PT89486B (pt) 1993-12-31
YU47298B (sh) 1995-01-31
BG60530B2 (bg) 1995-07-28
JPH0764806B2 (ja) 1995-07-12
FI890283A (fi) 1989-07-21
FI90764B (fi) 1993-12-15
CA1337529C (en) 1995-11-07
ES2033467T3 (es) 1993-03-16
KR960009119B1 (en) 1996-07-13
MC1998A1 (fr) 1990-01-26
AR247551A1 (es) 1995-01-31
NZ227641A (en) 1991-06-25
EP0325279A1 (de) 1989-07-26

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Legal Events

Date Code Title Description
FG3A Patent granted, date of granting

Effective date: 19930622

MM4A Annulment/lapse due to non-payment of fees, searched and examined patent

Free format text: LAPSE DUE TO NON-PAYMENT OF FEES

Effective date: 20071226