ZA8923B - 16-dehydro-vitamin d3-derivatives - Google Patents

16-dehydro-vitamin d3-derivatives

Info

Publication number
ZA8923B
ZA8923B ZA8923A ZA8923A ZA8923B ZA 8923 B ZA8923 B ZA 8923B ZA 8923 A ZA8923 A ZA 8923A ZA 8923 A ZA8923 A ZA 8923A ZA 8923 B ZA8923 B ZA 8923B
Authority
ZA
South Africa
Prior art keywords
dehydro
vitamin
derivatives
Prior art date
Application number
ZA8923A
Other languages
English (en)
Inventor
Enrico Giuseppe Baggiolini
Bernard Michael Hennessy
Shian-Jan Shiuey
Gary Arthur Truitt
Milan Radoje Uskokovic
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of ZA8923B publication Critical patent/ZA8923B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C401/00—Irradiation products of cholesterol or its derivatives; Vitamin D derivatives, 9,10-seco cyclopenta[a]phenanthrene or analogues obtained by chemical preparation without irradiation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/02—Nutrients, e.g. vitamins, minerals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02—Silicon compounds
    • C07F7/08—Compounds having one or more C—Si linkages
    • C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
    • C07F7/1804—Compounds having Si-O-C linkages

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Dermatology (AREA)
  • Nutrition Science (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
ZA8923A 1988-01-20 1989-01-03 16-dehydro-vitamin d3-derivatives ZA8923B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US14593288A 1988-01-20 1988-01-20

Publications (1)

Publication Number Publication Date
ZA8923B true ZA8923B (en) 1989-09-27

Family

ID=22515181

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA8923A ZA8923B (en) 1988-01-20 1989-01-03 16-dehydro-vitamin d3-derivatives

Country Status (23)

Country Link
EP (1) EP0325279B1 (xx)
JP (1) JPH0764806B2 (xx)
KR (1) KR960009119B1 (xx)
AR (1) AR247551A1 (xx)
AT (1) ATE74350T1 (xx)
AU (1) AU622139B2 (xx)
BG (1) BG60530B2 (xx)
CA (1) CA1337529C (xx)
DE (1) DE58901056D1 (xx)
DK (1) DK169945B1 (xx)
ES (1) ES2033467T3 (xx)
FI (1) FI90764C (xx)
GR (1) GR3004786T3 (xx)
HU (1) HU201007B (xx)
IE (1) IE60921B1 (xx)
IL (1) IL88989A (xx)
MC (1) MC1998A1 (xx)
NO (1) NO175429C (xx)
NZ (1) NZ227641A (xx)
PH (1) PH25605A (xx)
PT (1) PT89486B (xx)
YU (1) YU47298B (xx)
ZA (1) ZA8923B (xx)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4804502A (en) * 1988-01-20 1989-02-14 Hoffmann-La Roche Inc. Vitamin D compounds
EP0398217B1 (de) * 1989-05-18 1994-01-12 F. Hoffmann-La Roche Ag Dehydrocholecalciferolderivate
AU650751B2 (en) * 1991-05-28 1994-06-30 Wisconsin Alumni Research Foundation Novel synthesis of 19-nor vitamin D compounds
DK0580968T3 (da) * 1992-05-20 1996-10-14 Hoffmann La Roche Fluorerede analoger af vitamin D3
CA2096105A1 (en) * 1992-10-07 1994-04-08 Enrico Giuseppe Baggiolini (Deceased) Vitamin d3 fluorinated analogs
US5753638A (en) * 1992-10-07 1998-05-19 Hoffmann-La Roche Inc. Method of treating hyperproliferative skin disease with Vitamin D3 fluorinated analogs
TW267161B (xx) * 1992-11-20 1996-01-01 Hoffmann La Roche
US5401733A (en) * 1993-10-01 1995-03-28 Hoffmann-La Roche Inc. Stable and active metabolites of 1,25-dihydroxy-16-ene-cholecalciferol
US5428029A (en) * 1993-11-24 1995-06-27 Hoffmann-La Roche Inc. Vitamin D3 fluorinated analogs
TW403735B (en) * 1995-11-22 2000-09-01 Hoffmann La Roche 25-hydroxy-16-ene-26, 27-bishomo-cholecalciferol
AU708679B2 (en) * 1996-03-21 1999-08-12 F. Hoffmann-La Roche Ag 1,25-dihydroxy-16,22,23-trisdehydro-cholecalciferol derivatives
US5939408A (en) * 1996-05-23 1999-08-17 Hoffman-La Roche Inc. Vitamin D3 analogs
SG70009A1 (en) * 1996-05-23 2000-01-25 Hoffmann La Roche Vitamin d3 analogs
ATE237586T1 (de) * 1997-05-02 2003-05-15 Duphar Int Res Verfahren zur herstellung von 16-dehydro vitamin d verbindungen
US6331642B1 (en) * 1999-07-12 2001-12-18 Hoffmann-La Roche Inc. Vitamin D3 analogs
JP4795023B2 (ja) * 2004-02-03 2011-10-19 中外製薬株式会社 ビタミンｄ化合物及びそれらの合成中間体の合成方法
WO2006113990A2 (en) * 2005-04-25 2006-11-02 Cytochroma Inc. LOW-CALCEMIC 16,23-DIENE 25-OXIME ANALOGS OF 1α ,25-DIHYDROXY VITAMIN D3
CN101287705A (zh) * 2005-08-18 2008-10-15 拜奥艾克塞尔股份公司 1α-氟-25-羟基-16-23E-二烯-26,27-双高-20-表-胆骨化醇的合成

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1574685A (en) * 1977-03-24 1980-09-10 Wisconsin Alumni Res Found Vitamin d3 derivatives
FR2426044A2 (fr) * 1978-05-19 1979-12-14 Wisconsin Research Foundation Derives de la vitamine d3 ayant une activite anti-vitamine d
US4360471A (en) * 1981-12-11 1982-11-23 Wisconsin Alumni Research Foundation 23-Dehydro-25-hydroxyvitamin D3
US4508651A (en) * 1983-03-21 1985-04-02 Hoffmann-La Roche Inc. Synthesis of 1α,25-dihydroxyergocalciferol
US4505906A (en) * 1984-01-30 1985-03-19 Wisconsin Alumni Research Foundation Hydroxyvitamin D2 isomers
US4612308A (en) * 1984-11-29 1986-09-16 Hoffmann-La Roche Inc. 25,26-Dehydro-1α,23(S,R)-dihydroxycholecalciferol and its epimers
US4898855A (en) * 1987-09-14 1990-02-06 Hoffman-La Roche Inc. Deuterated analogs of 1,25-dihydroxycholecalciferol
US4804502A (en) * 1988-01-20 1989-02-14 Hoffmann-La Roche Inc. Vitamin D compounds
EP0398217B1 (de) * 1989-05-18 1994-01-12 F. Hoffmann-La Roche Ag Dehydrocholecalciferolderivate

Also Published As

Publication number Publication date
FI90764C (fi) 1994-03-25
ES2033467T3 (es) 1993-03-16
BG60530B2 (bg) 1995-07-28
IL88989A0 (en) 1989-08-15
FI890283A0 (fi) 1989-01-19
PH25605A (en) 1991-08-08
ATE74350T1 (de) 1992-04-15
HU201007B (en) 1990-09-28
PT89486B (pt) 1993-12-31
HUT49317A (en) 1989-09-28
GR3004786T3 (xx) 1993-04-28
JPH029861A (ja) 1990-01-12
CA1337529C (en) 1995-11-07
JPH0764806B2 (ja) 1995-07-12
NO890239L (no) 1989-07-21
EP0325279B1 (de) 1992-04-01
NZ227641A (en) 1991-06-25
FI90764B (fi) 1993-12-15
NO890239D0 (no) 1989-01-19
AR247551A1 (es) 1995-01-31
NO175429C (no) 1994-10-12
DE58901056D1 (de) 1992-05-07
KR960009119B1 (en) 1996-07-13
DK19789A (da) 1989-07-21
PT89486A (pt) 1989-10-04
AU622139B2 (en) 1992-04-02
AU2864489A (en) 1989-07-20
KR890011838A (ko) 1989-08-22
YU11789A (en) 1991-04-30
FI890283A (fi) 1989-07-21
IE60921B1 (en) 1994-09-07
IE890157L (en) 1989-07-20
EP0325279A1 (de) 1989-07-26
NO175429B (no) 1994-07-04
MC1998A1 (fr) 1990-01-26
YU47298B (sh) 1995-01-31
DK19789D0 (da) 1989-01-17
IL88989A (en) 1993-08-18
DK169945B1 (da) 1995-04-10

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