FI890283A7 - Menetelmä terapeuttisesti käyttökelpoisten 25-hydroksi-vitamiinin D-johdannaisten valmistamiseksi - Google Patents

Menetelmä terapeuttisesti käyttökelpoisten 25-hydroksi-vitamiinin D-johdannaisten valmistamiseksi

Info

Publication number
FI890283A7
FI890283A7 FI890283A FI890283A FI890283A7 FI 890283 A7 FI890283 A7 FI 890283A7 FI 890283 A FI890283 A FI 890283A FI 890283 A FI890283 A FI 890283A FI 890283 A7 FI890283 A7 FI 890283A7
Authority
FI
Finland
Prior art keywords
hydroxyvitamin
derivatives
therapeutically useful
preparing therapeutically
preparing
Prior art date
Application number
FI890283A
Other languages
English (en)
Swedish (sv)
Other versions
FI90764C (fi
FI890283A0 (fi
FI90764B (fi
Inventor
Enrico Giuseppe Baggiolini
Bernard Michael Hennessy
Shian-Jan Shiuey
Gary Arthur Truitt
Milan Radoje Uskokovic
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of FI890283A0 publication Critical patent/FI890283A0/fi
Publication of FI890283A7 publication Critical patent/FI890283A7/fi
Application granted granted Critical
Publication of FI90764B publication Critical patent/FI90764B/fi
Publication of FI90764C publication Critical patent/FI90764C/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C401/00—Irradiation products of cholesterol or its derivatives; Vitamin D derivatives, 9,10-seco cyclopenta[a]phenanthrene or analogues obtained by chemical preparation without irradiation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/02—Nutrients, e.g. vitamins, minerals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02—Silicon compounds
    • C07F7/08—Compounds having one or more C—Si linkages
    • C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
    • C07F7/1804—Compounds having Si-O-C linkages

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nutrition Science (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
FI890283A 1988-01-20 1989-01-19 Menetelmä terapeuttisesti käyttökelpoisten 25-hydroksi-vitamiinin D-johdannaisten valmistamiseksi FI90764C (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US14593288A 1988-01-20 1988-01-20
US14593288 1988-01-20

Publications (4)

Publication Number Publication Date
FI890283A0 FI890283A0 (fi) 1989-01-19
FI890283A7 true FI890283A7 (fi) 1989-07-21
FI90764B FI90764B (fi) 1993-12-15
FI90764C FI90764C (fi) 1994-03-25

Family

ID=22515181

Family Applications (1)

Application Number Title Priority Date Filing Date
FI890283A FI90764C (fi) 1988-01-20 1989-01-19 Menetelmä terapeuttisesti käyttökelpoisten 25-hydroksi-vitamiinin D-johdannaisten valmistamiseksi

Country Status (23)

Country Link
EP (1) EP0325279B1 (fi)
JP (1) JPH0764806B2 (fi)
KR (1) KR960009119B1 (fi)
AR (1) AR247551A1 (fi)
AT (1) ATE74350T1 (fi)
AU (1) AU622139B2 (fi)
BG (1) BG60530B2 (fi)
CA (1) CA1337529C (fi)
DE (1) DE58901056D1 (fi)
DK (1) DK169945B1 (fi)
ES (1) ES2033467T3 (fi)
FI (1) FI90764C (fi)
GR (1) GR3004786T3 (fi)
HU (1) HU201007B (fi)
IE (1) IE60921B1 (fi)
IL (1) IL88989A (fi)
MC (1) MC1998A1 (fi)
NO (1) NO175429C (fi)
NZ (1) NZ227641A (fi)
PH (1) PH25605A (fi)
PT (1) PT89486B (fi)
YU (1) YU47298B (fi)
ZA (1) ZA8923B (fi)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4804502A (en) * 1988-01-20 1989-02-14 Hoffmann-La Roche Inc. Vitamin D compounds
DE69005897D1 (de) * 1989-05-18 1994-02-24 Hoffmann La Roche Dehydrocholecalciferolderivate.
AU650751B2 (en) * 1991-05-28 1994-06-30 Wisconsin Alumni Research Foundation Novel synthesis of 19-nor vitamin D compounds
DE69304279T2 (de) * 1992-05-20 1997-02-20 Hoffmann La Roche Fluorierte Analoge Vitamins D3
CA2096105A1 (en) * 1992-10-07 1994-04-08 Enrico Giuseppe Baggiolini (Deceased) Vitamin d3 fluorinated analogs
US5753638A (en) * 1992-10-07 1998-05-19 Hoffmann-La Roche Inc. Method of treating hyperproliferative skin disease with Vitamin D3 fluorinated analogs
TW267161B (fi) * 1992-11-20 1996-01-01 Hoffmann La Roche
US5401733A (en) * 1993-10-01 1995-03-28 Hoffmann-La Roche Inc. Stable and active metabolites of 1,25-dihydroxy-16-ene-cholecalciferol
US5428029A (en) * 1993-11-24 1995-06-27 Hoffmann-La Roche Inc. Vitamin D3 fluorinated analogs
TW403735B (en) * 1995-11-22 2000-09-01 Hoffmann La Roche 25-hydroxy-16-ene-26, 27-bishomo-cholecalciferol
AU708679B2 (en) * 1996-03-21 1999-08-12 F. Hoffmann-La Roche Ag 1,25-dihydroxy-16,22,23-trisdehydro-cholecalciferol derivatives
US5939408A (en) * 1996-05-23 1999-08-17 Hoffman-La Roche Inc. Vitamin D3 analogs
SG70009A1 (en) * 1996-05-23 2000-01-25 Hoffmann La Roche Vitamin d3 analogs
DK0884308T3 (da) * 1997-05-02 2003-07-21 Duphar Int Res Fremgangsmåde til at fremstille 16-dehydro vitamin D forbindelser
US6331642B1 (en) * 1999-07-12 2001-12-18 Hoffmann-La Roche Inc. Vitamin D3 analogs
US9221753B2 (en) * 2004-02-03 2015-12-29 Chugai Seiyaku Kabushiki Kaisha Process for the synthesis of vitamin D compounds and intermediates for the synthesis of the compounds
EP1883626B1 (en) * 2005-04-25 2017-10-11 OPKO Ireland Global Holdings, Ltd. Low-calcemic 16,23-diene 25-oxime analogs of 1alpha,25-dihydroxy vitamin d3
US20090137828A1 (en) * 2005-08-18 2009-05-28 Bioxell S.P.A. Synthesis of 1A-Fluoro-25-Hydroxy-16-23E-Diene-26,27-Bishomo-20-Epi-Cholecalciferol

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1574685A (en) * 1977-03-24 1980-09-10 Wisconsin Alumni Res Found Vitamin d3 derivatives
FR2426044A2 (fr) * 1978-05-19 1979-12-14 Wisconsin Research Foundation Derives de la vitamine d3 ayant une activite anti-vitamine d
US4360471A (en) * 1981-12-11 1982-11-23 Wisconsin Alumni Research Foundation 23-Dehydro-25-hydroxyvitamin D3
US4508651A (en) * 1983-03-21 1985-04-02 Hoffmann-La Roche Inc. Synthesis of 1α,25-dihydroxyergocalciferol
US4505906A (en) * 1984-01-30 1985-03-19 Wisconsin Alumni Research Foundation Hydroxyvitamin D2 isomers
US4612308A (en) * 1984-11-29 1986-09-16 Hoffmann-La Roche Inc. 25,26-Dehydro-1α,23(S,R)-dihydroxycholecalciferol and its epimers
US4898855A (en) * 1987-09-14 1990-02-06 Hoffman-La Roche Inc. Deuterated analogs of 1,25-dihydroxycholecalciferol
US4804502A (en) * 1988-01-20 1989-02-14 Hoffmann-La Roche Inc. Vitamin D compounds
DE69005897D1 (de) * 1989-05-18 1994-02-24 Hoffmann La Roche Dehydrocholecalciferolderivate.

Also Published As

Publication number Publication date
NZ227641A (en) 1991-06-25
NO175429B (no) 1994-07-04
IL88989A0 (en) 1989-08-15
MC1998A1 (fr) 1990-01-26
NO890239D0 (no) 1989-01-19
NO175429C (no) 1994-10-12
KR960009119B1 (en) 1996-07-13
YU11789A (en) 1991-04-30
DK19789D0 (da) 1989-01-17
PT89486A (pt) 1989-10-04
JPH0764806B2 (ja) 1995-07-12
HUT49317A (en) 1989-09-28
FI90764C (fi) 1994-03-25
AU2864489A (en) 1989-07-20
DK19789A (da) 1989-07-21
HU201007B (en) 1990-09-28
GR3004786T3 (fi) 1993-04-28
ES2033467T3 (es) 1993-03-16
JPH029861A (ja) 1990-01-12
DK169945B1 (da) 1995-04-10
PH25605A (en) 1991-08-08
FI890283A0 (fi) 1989-01-19
IE60921B1 (en) 1994-09-07
BG60530B2 (bg) 1995-07-28
EP0325279A1 (de) 1989-07-26
AU622139B2 (en) 1992-04-02
ZA8923B (en) 1989-09-27
DE58901056D1 (de) 1992-05-07
YU47298B (sh) 1995-01-31
ATE74350T1 (de) 1992-04-15
IE890157L (en) 1989-07-20
PT89486B (pt) 1993-12-31
NO890239L (no) 1989-07-21
CA1337529C (en) 1995-11-07
EP0325279B1 (de) 1992-04-01
AR247551A1 (es) 1995-01-31
KR890011838A (ko) 1989-08-22
FI90764B (fi) 1993-12-15
IL88989A (en) 1993-08-18

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Legal Events

Date Code Title Description
BB Publication of examined application
FG Patent granted

Owner name: F. HOFFMANN-LA ROCHE AG

MA Patent expired