NO170929C - Analogifremgangsmaate for fremstilling av terapeutisk aktive benzotiazolforbindelser - Google Patents

Analogifremgangsmaate for fremstilling av terapeutisk aktive benzotiazolforbindelser

Info

Publication number
NO170929C
NO170929C NO882627A NO882627A NO170929C NO 170929 C NO170929 C NO 170929C NO 882627 A NO882627 A NO 882627A NO 882627 A NO882627 A NO 882627A NO 170929 C NO170929 C NO 170929C
Authority
NO
Norway
Prior art keywords
compounds
benzotiazol
preparation
therapeutic active
analogy procedure
Prior art date
Application number
NO882627A
Other languages
English (en)
Norwegian (no)
Other versions
NO882627L (no
NO170929B (no
NO882627D0 (no
Inventor
Shinya Abe
Mitsuaki Miyamoto
Masayuki Tanaka
Kozo Akasaka
Kenji Hayashi
Tetsuya Kawahara
Satoshi Katayama
Yoshinori Sakuma
Takeshi Suzuki
Isao Yamatsu
Original Assignee
Eisai Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eisai Co Ltd filed Critical Eisai Co Ltd
Publication of NO882627D0 publication Critical patent/NO882627D0/no
Publication of NO882627L publication Critical patent/NO882627L/no
Publication of NO170929B publication Critical patent/NO170929B/no
Publication of NO170929C publication Critical patent/NO170929C/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/60—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings condensed with carbocyclic rings or ring systems
    • C07D277/62—Benzothiazoles
    • C07D277/68—Benzothiazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • C07D277/82—Nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/60—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings condensed with carbocyclic rings or ring systems
    • C07D277/84—Naphthothiazoles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pulmonology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Paper (AREA)
NO882627A 1987-06-17 1988-06-15 Analogifremgangsmaate for fremstilling av terapeutisk aktive benzotiazolforbindelser NO170929C (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP15098787 1987-06-17

Publications (4)

Publication Number Publication Date
NO882627D0 NO882627D0 (no) 1988-06-15
NO882627L NO882627L (no) 1988-12-19
NO170929B NO170929B (no) 1992-09-21
NO170929C true NO170929C (no) 1993-01-06

Family

ID=15508808

Family Applications (1)

Application Number Title Priority Date Filing Date
NO882627A NO170929C (no) 1987-06-17 1988-06-15 Analogifremgangsmaate for fremstilling av terapeutisk aktive benzotiazolforbindelser

Country Status (21)

Country Link
US (1) US4929623A (fi)
EP (1) EP0295656B1 (fi)
JP (1) JP2793195B2 (fi)
KR (1) KR910005709B1 (fi)
CN (1) CN1030757A (fi)
AT (1) ATE82276T1 (fi)
AU (1) AU610186B2 (fi)
CA (1) CA1322369C (fi)
DD (1) DD282686A5 (fi)
DE (1) DE3875809T2 (fi)
DK (1) DK328888A (fi)
ES (1) ES2045017T3 (fi)
FI (1) FI91859C (fi)
GR (1) GR3006207T3 (fi)
HU (1) HU205347B (fi)
NO (1) NO170929C (fi)
NZ (1) NZ224946A (fi)
PH (1) PH26553A (fi)
PT (1) PT87747B (fi)
SU (1) SU1731051A3 (fi)
ZA (1) ZA884277B (fi)

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CA2258822A1 (en) 1996-06-20 1997-12-24 Sean Kerwin Compounds and methods for providing pharmacologically active preparations and uses thereof
JP2002516820A (ja) * 1997-11-13 2002-06-11 ヒスタテク・エルエルシー 低分子量ペプチド及び喘息及び炎症の治療方法
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AU3487500A (en) * 1999-02-08 2000-08-25 Lion Bioscience Ag Thiazole derivatives and combinatorial libraries thereof
ATE296814T1 (de) * 1999-05-12 2005-06-15 Neurosearch As Ionenkanal modulierende mittel
US6495549B1 (en) 1999-07-15 2002-12-17 Pfizer Inc FKBP inhibitors
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WO2001085722A1 (en) * 2000-05-05 2001-11-15 Cor Therapeutics, Inc. Heterobicyclic sulfonamides and their use as platelet adp receptor inhibitors
US6756047B2 (en) 2000-05-12 2004-06-29 The University Of Toledo Method and compositions for treating persistent pulmonary hypertension using aralkyl ester soft drugs
US6750238B1 (en) * 2000-05-12 2004-06-15 The University Of Toledo Aralkyl ester soft drugs
US7049326B2 (en) * 2000-05-12 2006-05-23 The University Of Toledo Method and compositions for temporarily incapacitating subjects
MXPA02012596A (es) 2000-06-21 2003-04-10 Hoffmann La Roche Derivados de benzotiazol.
US6620811B2 (en) 2001-11-19 2003-09-16 Hoffmann-La Roche Inc. Isonicotin- and nicotinamide derivatives of benzothiazoles
US6624163B2 (en) 2001-11-29 2003-09-23 Hoffman-La Roche Inc. Benzothiazole derivatives
US7338956B2 (en) * 2002-08-07 2008-03-04 Sanofi-Aventis Deutschland Gmbh Acylamino-substituted heteroaromatic compounds and their use as pharmaceuticals
US7087761B2 (en) 2003-01-07 2006-08-08 Hoffmann-La Roche Inc. Cyclization process for substituted benzothiazole derivatives
US7601746B2 (en) 2003-08-12 2009-10-13 Shionogi & Co., Ltd. Compounds exhibiting thrombopoietin receptor agonism
US20050118291A1 (en) * 2003-09-10 2005-06-02 Mian-Ying Wang Formulations and methods for treating breast cancer with Morinda citrifolia and methylsulfonymethane
JP4668265B2 (ja) 2004-05-24 2011-04-13 エフ．ホフマン−ラ ロシュ アーゲー ４−ヒドロキシ−４−メチル−ピペリジン−１−カルボン酸（４−メトキシ−７−モルホリン−４−イル−ベンゾチアゾール−２−イル）−アミド
WO2006013054A1 (en) * 2004-08-05 2006-02-09 F. Hoffmann-La Roche Ag Substituted n-acyl-2-aminothiazoles
ATE400557T1 (de) 2004-11-05 2008-07-15 Hoffmann La Roche Verfahren zur herstellung von isonikotinsäurederivaten
MX2007011483A (es) 2005-03-23 2007-10-12 Hoffmann La Roche Derivados de acetilenil-pirazolo-pirimidina como antagonistas de glutamato metabotropico 2.
CA2623721C (en) 2005-09-27 2014-05-13 F. Hoffmann-La Roche Ag Oxadiazolyl pyrazolo-pyrimidines as mglur2 antagonists
WO2007110364A1 (en) 2006-03-28 2007-10-04 High Point Pharmaceuticals, Llc Benzothiazoles having histamine h3 receptor activity
EP2336125B1 (en) * 2008-04-11 2013-01-09 Janssen Pharmaceutica N.V. Thiazolopyridin-2-yloxy-phenyl and thiazolopyrazin-2-yloxy-phenyl amines as modulators of leukotriene A4 hydrolase
UY32138A (es) 2008-09-25 2010-04-30 Boehringer Ingelheim Int Amidas sustituidas del ácido 2-(2,6-dicloro-fenilamino)-6-fluoro-1-metil-1h-bencimidazol-5-carboxílico y sus sales farmacéuticamente aceptables
UY32470A (es) 2009-03-05 2010-10-29 Boehringer Ingelheim Int Derivados de 2-{2-cloro-5-[(sustituido) metil]fenilamino} -1-metil]fenilamino}-1-metilbencimidazol-5-carboxamidas-n-(sustituidas) y sus sales fisiológicamente aceptables, composiciones conteniéndolos y aplicaciones
WO2010106016A1 (en) * 2009-03-17 2010-09-23 Glaxo Group Limited Pyrimidine derivatives used as itk inhibitors
US8759537B2 (en) 2010-08-20 2014-06-24 Boehringer Ingelheim International Gmbh 3H-imidazo [4, 5-C] pyridine-6-carboxamides as anti-inflammatory agents
US8586604B2 (en) 2010-08-20 2013-11-19 Boehringer Ingelheim International Gmbh Inhibitors of the microsomal prostaglandin E2 synthase-1
US8486968B2 (en) 2010-12-10 2013-07-16 Boehringer Ingelheim International Gmbh Compounds
UY33779A (es) 2010-12-10 2012-07-31 Boehringer Ingelheim Int ?2-(fenilamino)-1H-bencimidazol-5-carboxamidas novedosas?
US8466186B2 (en) 2010-12-10 2013-06-18 Boehringer Ingelheim International Gmbh Compounds
CN102872012B (zh) * 2011-11-03 2015-03-25 成都医学院 一种抑制蛋白激酶化合物的用途
CN113959912B (zh) * 2020-07-20 2024-06-21 深圳迈瑞生物医疗电子股份有限公司 抗血小板聚集干扰的白细胞检测方法、试剂及其应用
CN113959911B (zh) * 2020-07-20 2024-06-18 深圳迈瑞生物医疗电子股份有限公司 抗血小板聚集干扰的检测方法、试剂及其应用

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DE927507C (de) * 1953-02-24 1955-05-09 Bayer Ag Verfahren zur Herstellung von Derivaten des 6-Oxy-2-aminobenzthiazols
GB808191A (en) * 1956-07-13 1959-01-28 Robert Ronald Davies New dyestuff intermediates
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DK148476C (da) * 1975-04-25 1985-12-16 Scherico Ltd Analogifremgangsmaade til fremstilling af methyl-6-n-propoxybenzothiazol-2-carbamat
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Also Published As

Publication number Publication date
ZA884277B (en) 1989-03-29
AU610186B2 (en) 1991-05-16
FI882692A (fi) 1988-12-18
KR890000451A (ko) 1989-03-14
KR910005709B1 (ko) 1991-08-02
FI882692A0 (fi) 1988-06-07
GR3006207T3 (fi) 1993-06-21
JP2793195B2 (ja) 1998-09-03
DK328888D0 (da) 1988-06-16
JPS6479162A (en) 1989-03-24
HUT47554A (en) 1989-03-28
NO882627L (no) 1988-12-19
NO170929B (no) 1992-09-21
PT87747B (pt) 1992-10-30
CA1322369C (en) 1993-09-21
ATE82276T1 (de) 1992-11-15
DK328888A (da) 1988-12-18
DE3875809D1 (de) 1992-12-17
PH26553A (en) 1992-08-19
CN1030757A (zh) 1989-02-01
DE3875809T2 (de) 1993-04-15
SU1731051A3 (ru) 1992-04-30
AU1769988A (en) 1988-12-22
ES2045017T3 (es) 1994-01-16
DD282686A5 (de) 1990-09-19
FI91859C (fi) 1994-08-25
NO882627D0 (no) 1988-06-15
NZ224946A (en) 1990-07-26
EP0295656B1 (en) 1992-11-11
US4929623A (en) 1990-05-29
EP0295656A1 (en) 1988-12-21
HU205347B (en) 1992-04-28
PT87747A (pt) 1988-07-01
FI91859B (fi) 1994-05-13

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