ATE77087T1 - Thiazolidindione als hypoglykaemische und antiatherosklerotische mittel. - Google Patents
Thiazolidindione als hypoglykaemische und antiatherosklerotische mittel.Info
- Publication number
- ATE77087T1 ATE77087T1 AT88311018T AT88311018T ATE77087T1 AT E77087 T1 ATE77087 T1 AT E77087T1 AT 88311018 T AT88311018 T AT 88311018T AT 88311018 T AT88311018 T AT 88311018T AT E77087 T1 ATE77087 T1 AT E77087T1
- Authority
- AT
- Austria
- Prior art keywords
- hypoglycemic
- thiazolidindiones
- antiatherosclerotic agents
- agents
- antiatherosclerotic
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Diabetes (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Obesity (AREA)
- Heart & Thoracic Surgery (AREA)
- Endocrinology (AREA)
- Emergency Medicine (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Cardiology (AREA)
- Hematology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Seasonings (AREA)
- Pyrrole Compounds (AREA)
- Cosmetics (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US07/127,831 US4791125A (en) | 1987-12-02 | 1987-12-02 | Thiazolidinediones as hypoglycemic and anti-atherosclerosis agents |
EP88311018A EP0319189B1 (de) | 1987-12-02 | 1988-11-22 | Thiazolidindione als hypoglykämische und antiatherosklerotische Mittel |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE77087T1 true ATE77087T1 (de) | 1992-06-15 |
Family
ID=22432189
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT88311018T ATE77087T1 (de) | 1987-12-02 | 1988-11-22 | Thiazolidindione als hypoglykaemische und antiatherosklerotische mittel. |
Country Status (11)
Country | Link |
---|---|
US (1) | US4791125A (de) |
EP (1) | EP0319189B1 (de) |
JP (1) | JPH01186884A (de) |
AT (1) | ATE77087T1 (de) |
DE (1) | DE3871916T2 (de) |
DK (1) | DK671088A (de) |
ES (1) | ES2037243T3 (de) |
FI (1) | FI89356C (de) |
GR (1) | GR3004902T3 (de) |
IE (1) | IE883599L (de) |
PT (1) | PT89122B (de) |
Families Citing this family (37)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
HU203330B (en) * | 1987-06-10 | 1991-07-29 | Pfizer | Process for producing oxazolidin-2-one derivatives and hypoglychemic pharmaceutical compositions containing them |
US5053420A (en) * | 1989-10-13 | 1991-10-01 | Pershadsingh Harrihar A | Thiazolidine derivatives for the treatment of hypertension |
WO1991007107A1 (en) * | 1989-11-13 | 1991-05-30 | Pfizer Inc. | Oxazolidinedione hypoglycemic agents |
US5037842A (en) * | 1990-06-05 | 1991-08-06 | Pfizer Inc. | Oxa- and thiazolidinedione hypoglycemic and hypocholesterolemic agents |
EP0494405B2 (de) * | 1991-01-10 | 2000-04-19 | Transcend Therapeutics, Inc. | Verwendung von L-2-oxo Thiazolidin-4-carboxylat zur Behandlung von Atemnotsyndrom |
US5747459A (en) * | 1991-02-04 | 1998-05-05 | Nestec, Ltd. | Method for insuring adequate intracellular glutathione in tissue |
US5866595A (en) * | 1991-09-26 | 1999-02-02 | The Regents Of The University Of California | Calcium antagonists for treatment of vascular restenosis |
US5430045A (en) * | 1992-04-23 | 1995-07-04 | Free Radical Sciences, Inc. | Method of reducing or preventing bone marrow hypoplasia |
US5498621A (en) * | 1992-05-01 | 1996-03-12 | Pfizer Inc. | Oxazolidinedione hypoglycemic agents |
US5306724A (en) * | 1992-08-17 | 1994-04-26 | Clintec Nutrition Company | Method for preventing and treating atherosclerosis |
US5447712A (en) * | 1993-12-09 | 1995-09-05 | Free Radical Sciences | Method of reducing cyclophosphamide induced hemorrhagic cystitis |
US5641796A (en) * | 1994-11-01 | 1997-06-24 | Eli Lilly And Company | Oral hypoglycemic agents |
AP1600A (en) | 1997-06-18 | 2006-04-28 | Smithkline Beecham Plc | Combination of a thiazolidinedione and a sulphonylurea for treating diabetes |
GB9715295D0 (en) * | 1997-07-18 | 1997-09-24 | Smithkline Beecham Plc | Novel method of treatment |
GB9715306D0 (en) * | 1997-07-18 | 1997-09-24 | Smithkline Beecham Plc | Novel method of treatment |
GB9824893D0 (en) * | 1998-11-12 | 1999-01-06 | Smithkline Beckman Corp | Novel method of treatment |
AR023699A1 (es) | 1998-11-12 | 2002-09-04 | Smithkline Beecham Corp | Una composicion farmaceutica que comprende un estabilizador de insulina y un procedimiento para preparar una composicion farmaceutica |
BR9915285A (pt) * | 1998-11-12 | 2001-08-07 | Smithkline Beecham Plc | Composição farmacêutica para liberação modificada de um sensitivador de insulina e um outro agente antidiabético |
US6756360B1 (en) | 1998-12-24 | 2004-06-29 | Metabasis Therapeutics, Inc. | Combination of FBPase inhibitors and insulin sensitizers for the treatment of diabetes |
JP2001072592A (ja) | 1999-07-01 | 2001-03-21 | Kyowa Hakko Kogyo Co Ltd | テロメラーゼ阻害剤 |
WO2001047935A2 (en) * | 1999-12-22 | 2001-07-05 | Metabasis Therapeutics, Inc. | Novel bisamidate phosphonate prodrugs |
GB0014969D0 (en) | 2000-06-19 | 2000-08-09 | Smithkline Beecham Plc | Novel method of treatment |
US7563774B2 (en) | 2000-06-29 | 2009-07-21 | Metabasis Therapeutics, Inc. | Combination of FBPase inhibitors and antidiabetic agents useful for the treatment of diabetes |
US6452014B1 (en) | 2000-12-22 | 2002-09-17 | Geron Corporation | Telomerase inhibitors and methods of their use |
US9655865B2 (en) | 2002-07-29 | 2017-05-23 | Veroscience, Llc | Therapeutic treatment for metabolic syndrome, type 2 diabetes, obesity, or prediabetes |
US20080200453A1 (en) * | 2002-07-29 | 2008-08-21 | Cincotta Anthony H | Methods of treating metabolic syndrome using dopamine receptor agonists |
US8216609B2 (en) * | 2002-08-05 | 2012-07-10 | Torrent Pharmaceuticals Limited | Modified release composition of highly soluble drugs |
US8268352B2 (en) * | 2002-08-05 | 2012-09-18 | Torrent Pharmaceuticals Limited | Modified release composition for highly soluble drugs |
US8821915B2 (en) | 2002-08-09 | 2014-09-02 | Veroscience, Llc | Therapeutic process for the treatment of the metabolic syndrome and associated metabolic disorders |
BRPI0514372A (pt) * | 2004-08-18 | 2008-06-10 | Metabasis Therapeutics Inc | inibidores de tiazol de frutose 1, 6-bisfosfatase |
EP3524248A1 (de) | 2007-06-21 | 2019-08-14 | VeroScience LLC | Verfahren zur behandlung von metabolischen störungen und depressionen mit dopaminrezeptoragonisten |
US20100035886A1 (en) | 2007-06-21 | 2010-02-11 | Veroscience, Llc | Parenteral formulations of dopamine agonists |
US8741918B2 (en) | 2007-06-21 | 2014-06-03 | Veroscience Llc | Parenteral formulations of dopamine agonists |
US9352025B2 (en) | 2009-06-05 | 2016-05-31 | Veroscience Llc | Combination of dopamine agonists plus first phase insulin secretagogues for the treatment of metabolic disorders |
US20120094959A1 (en) | 2010-10-19 | 2012-04-19 | Bonnie Blazer-Yost | Treatment of cystic diseases |
US8431155B1 (en) | 2012-04-30 | 2013-04-30 | Veroscience Llc | Bromocriptine formulations |
US10034868B2 (en) | 2014-11-04 | 2018-07-31 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Methods for the prevention and the treatment of rapidly progressive glomerulonephritis |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS5522636A (en) * | 1978-08-04 | 1980-02-18 | Takeda Chem Ind Ltd | Thiazoliding derivative |
JPS58118577A (ja) * | 1982-01-07 | 1983-07-14 | Takeda Chem Ind Ltd | チアゾリジン誘導体 |
US4617312A (en) * | 1983-01-17 | 1986-10-14 | Pfizer Inc. | Aldose reductase inhibiting 5-(2-alkoxyphenyl) thiazolidinediones |
JPS6051189A (ja) * | 1983-08-30 | 1985-03-22 | Sankyo Co Ltd | チアゾリジン誘導体およびその製造法 |
AR240698A1 (es) * | 1985-01-19 | 1990-09-28 | Takeda Chemical Industries Ltd | Procedimiento para preparar compuestos de 5-(4-(2-(5-etil-2-piridil)-etoxi)benzil)-2,4-tiazolidindiona y sus sales |
US4703052A (en) * | 1985-05-21 | 1987-10-27 | Pfizer Inc. | Hypoglycemic thiazolidinediones |
JPH1036284A (ja) * | 1996-07-24 | 1998-02-10 | Sumitomo Pharmaceut Co Ltd | プロテアソーム阻害剤 |
-
1987
- 1987-12-02 US US07/127,831 patent/US4791125A/en not_active Expired - Lifetime
-
1988
- 1988-11-22 DE DE8888311018T patent/DE3871916T2/de not_active Expired - Lifetime
- 1988-11-22 EP EP88311018A patent/EP0319189B1/de not_active Expired - Lifetime
- 1988-11-22 AT AT88311018T patent/ATE77087T1/de active
- 1988-11-22 ES ES198888311018T patent/ES2037243T3/es not_active Expired - Lifetime
- 1988-11-30 PT PT89122A patent/PT89122B/pt not_active IP Right Cessation
- 1988-11-30 JP JP63303853A patent/JPH01186884A/ja active Granted
- 1988-12-01 IE IE883599A patent/IE883599L/xx unknown
- 1988-12-01 DK DK671088A patent/DK671088A/da not_active Application Discontinuation
- 1988-12-01 FI FI885594A patent/FI89356C/fi not_active IP Right Cessation
-
1992
- 1992-06-11 GR GR920401246T patent/GR3004902T3/el unknown
Also Published As
Publication number | Publication date |
---|---|
ES2037243T3 (es) | 1993-06-16 |
PT89122B (pt) | 1993-05-31 |
FI89356C (fi) | 1993-09-27 |
DK671088D0 (da) | 1988-12-01 |
GR3004902T3 (de) | 1993-04-28 |
FI89356B (fi) | 1993-06-15 |
DK671088A (da) | 1989-07-20 |
FI885594A (fi) | 1989-06-03 |
JPH01186884A (ja) | 1989-07-26 |
PT89122A (pt) | 1989-12-29 |
DE3871916T2 (de) | 1992-12-03 |
US4791125A (en) | 1988-12-13 |
JPH0465075B2 (de) | 1992-10-16 |
EP0319189B1 (de) | 1992-06-10 |
IE883599L (en) | 1989-06-02 |
FI885594A0 (fi) | 1988-12-01 |
DE3871916D1 (de) | 1992-07-16 |
EP0319189A1 (de) | 1989-06-07 |
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