GR3006207T3 - - Google Patents

Info

Publication number
GR3006207T3
GR3006207T3 GR920401328T GR920401328T GR3006207T3 GR 3006207 T3 GR3006207 T3 GR 3006207T3 GR 920401328 T GR920401328 T GR 920401328T GR 920401328 T GR920401328 T GR 920401328T GR 3006207 T3 GR3006207 T3 GR 3006207T3
Authority
GR
Greece
Prior art keywords
effective
affections
nr5r6
affection
leukotriene
Prior art date
Application number
GR920401328T
Other languages
English (en)
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Publication of GR3006207T3 publication Critical patent/GR3006207T3/el

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/04Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/06Antiasthmatics
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D277/00Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/60Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings condensed with carbocyclic rings or ring systems
    • C07D277/62Benzothiazoles
    • C07D277/68Benzothiazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • C07D277/82Nitrogen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D277/00Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/60Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings condensed with carbocyclic rings or ring systems
    • C07D277/84Naphthothiazoles
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D513/00Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pulmonology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Paper (AREA)
GR920401328T 1987-06-17 1992-11-12 GR3006207T3 (el)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP15098787 1987-06-17

Publications (1)

Publication Number Publication Date
GR3006207T3 true GR3006207T3 (el) 1993-06-21

Family

ID=15508808

Family Applications (1)

Application Number Title Priority Date Filing Date
GR920401328T GR3006207T3 (el) 1987-06-17 1992-11-12

Country Status (21)

Country Link
US (1) US4929623A (el)
EP (1) EP0295656B1 (el)
JP (1) JP2793195B2 (el)
KR (1) KR910005709B1 (el)
CN (1) CN1030757A (el)
AT (1) ATE82276T1 (el)
AU (1) AU610186B2 (el)
CA (1) CA1322369C (el)
DD (1) DD282686A5 (el)
DE (1) DE3875809T2 (el)
DK (1) DK328888A (el)
ES (1) ES2045017T3 (el)
FI (1) FI91859C (el)
GR (1) GR3006207T3 (el)
HU (1) HU205347B (el)
NO (1) NO170929C (el)
NZ (1) NZ224946A (el)
PH (1) PH26553A (el)
PT (1) PT87747B (el)
SU (1) SU1731051A3 (el)
ZA (1) ZA884277B (el)

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DE68903484T2 (de) * 1988-12-15 1993-03-18 Rhone Poulenc Sante 2-imino-6-polyfluoralkoxy-benzothiazol-derivate, verfahren zu deren herstellung und arzneimittel, die sie enthalten.
IL97249A (en) * 1990-02-23 1995-01-24 Takeda Chemical Industries Ltd Compounds of 7,6,5,4-tetrahydrothiazole] B-5,4 [pyridine and compounds of 5,6-dihydro-H4-pyrrolo] D-3,2 [thiazole, their manufacture, and pharmaceutical compositions including or
IE920921A1 (en) * 1991-04-04 1992-10-07 Eisai Co Ltd Benzothiazole derivative
US5296486A (en) * 1991-09-24 1994-03-22 Boehringer Ingelheim Pharmaceuticals, Inc. Leukotriene biosynthesis inhibitors
US5350760A (en) * 1993-08-04 1994-09-27 Merck Frosst Canada, Inc. Aza-5,5-fused hetrocyclic acids as leukotriene antagonists
EP0912549A4 (en) * 1996-06-20 2002-01-02 Univ Texas CONNECTIONS AND METHOD FOR PROVIDING ACTIVE PREPARATIONS AND THE USE THEREOF
WO1999025372A1 (en) 1997-11-13 1999-05-27 Histatek, Llc Small peptides and methods for treatment of asthma and inflammation
GB9815696D0 (en) * 1998-07-20 1998-09-16 Pfizer Ltd Heterocyclics
US6686357B1 (en) 1999-07-15 2004-02-03 Pfizer, Inc. FKBP inhibitors
AU3487500A (en) * 1999-02-08 2000-08-25 Lion Bioscience Ag Thiazole derivatives and combinatorial libraries thereof
ATE296814T1 (de) * 1999-05-12 2005-06-15 Neurosearch As Ionenkanal modulierende mittel
TWI284639B (en) * 2000-01-24 2007-08-01 Shionogi & Co A compound having thrombopoietin receptor agonistic effect
CA2408156A1 (en) * 2000-05-05 2001-11-15 Millennium Pharmaceuticals, Inc. Heterobicyclic sulfonamides and their use as platelet adp receptor inhibitors
US6750238B1 (en) * 2000-05-12 2004-06-15 The University Of Toledo Aralkyl ester soft drugs
US7049326B2 (en) * 2000-05-12 2006-05-23 The University Of Toledo Method and compositions for temporarily incapacitating subjects
US6756047B2 (en) * 2000-05-12 2004-06-29 The University Of Toledo Method and compositions for treating persistent pulmonary hypertension using aralkyl ester soft drugs
YU96502A (sh) 2000-06-21 2006-01-16 F. Hoffmann-La Roche Ag. Derivati benzotiazola
US6620811B2 (en) * 2001-11-19 2003-09-16 Hoffmann-La Roche Inc. Isonicotin- and nicotinamide derivatives of benzothiazoles
US6624163B2 (en) 2001-11-29 2003-09-23 Hoffman-La Roche Inc. Benzothiazole derivatives
US7338956B2 (en) * 2002-08-07 2008-03-04 Sanofi-Aventis Deutschland Gmbh Acylamino-substituted heteroaromatic compounds and their use as pharmaceuticals
US7087761B2 (en) 2003-01-07 2006-08-08 Hoffmann-La Roche Inc. Cyclization process for substituted benzothiazole derivatives
US20050118291A1 (en) * 2003-09-10 2005-06-02 Mian-Ying Wang Formulations and methods for treating breast cancer with Morinda citrifolia and methylsulfonymethane
CA2535511C (en) 2003-08-12 2009-11-17 Shionogi And Co., Ltd. Compounds having thrombopoietin receptor agonism
WO2005116026A1 (en) 2004-05-24 2005-12-08 F. Hoffmann-La Roche Ag 4-hydroxy-4-methyl-piperidine-1-carboxylic acid (4-methoxy-7-morpholin-4-yl-benzothiazol-2-yl)-amide
RU2371438C2 (ru) * 2004-08-05 2009-10-27 Ф.Хоффманн-Ля Рош Аг Замещенные 2-ацил-2-аминотиазолы
DE602005008095D1 (de) 2004-11-05 2008-08-21 Hoffmann La Roche Verfahren zur herstellung von isonikotinsäurederivaten
WO2006099972A1 (en) 2005-03-23 2006-09-28 F. Hoffmann-La Roche Ag Acetylenyl-pyrazolo-pvrimidine derivatives as mglur2 antagonists
ES2340321T3 (es) 2005-09-27 2010-06-01 F.Hoffmann-La Roche Ag Oxadiazolilpirazolo-pirimidinas, como antagonistas de mglur2.
AU2007229492B2 (en) 2006-03-28 2011-11-03 High Point Pharmaceuticals, Llc Benzothiazoles having histamine H3 receptor activity
CL2009000877A1 (es) * 2008-04-11 2009-11-27 Janssen Pharmaceutica Nv Compuestos derivados de [tiazolopiridin o tiazolopirazin-2-iloxi fenilamina; proceso de preparacion; composicion farmaceutica; y uso para el tratamiento de un trastorno o afeccion mediado por leucotrieno a4 hidrolasa, tales como alergia, asma, inflamacion, psoriasis, lupus, miastenia gravis, entre otros.
UY32138A (es) 2008-09-25 2010-04-30 Boehringer Ingelheim Int Amidas sustituidas del ácido 2-(2,6-dicloro-fenilamino)-6-fluoro-1-metil-1h-bencimidazol-5-carboxílico y sus sales farmacéuticamente aceptables
UY32470A (es) 2009-03-05 2010-10-29 Boehringer Ingelheim Int Derivados de 2-{2-cloro-5-[(sustituido) metil]fenilamino} -1-metil]fenilamino}-1-metilbencimidazol-5-carboxamidas-n-(sustituidas) y sus sales fisiológicamente aceptables, composiciones conteniéndolos y aplicaciones
WO2010106016A1 (en) * 2009-03-17 2010-09-23 Glaxo Group Limited Pyrimidine derivatives used as itk inhibitors
US8759537B2 (en) 2010-08-20 2014-06-24 Boehringer Ingelheim International Gmbh 3H-imidazo [4, 5-C] pyridine-6-carboxamides as anti-inflammatory agents
US8586604B2 (en) 2010-08-20 2013-11-19 Boehringer Ingelheim International Gmbh Inhibitors of the microsomal prostaglandin E2 synthase-1
US8466186B2 (en) 2010-12-10 2013-06-18 Boehringer Ingelheim International Gmbh Compounds
US8486968B2 (en) 2010-12-10 2013-07-16 Boehringer Ingelheim International Gmbh Compounds
US8674113B2 (en) 2010-12-10 2014-03-18 Boehringer Ingelheim International Gmbh Compounds
CN102872012B (zh) * 2011-11-03 2015-03-25 成都医学院 一种抑制蛋白激酶化合物的用途
CN113959912A (zh) * 2020-07-20 2022-01-21 深圳迈瑞生物医疗电子股份有限公司 抗血小板聚集干扰的白细胞检测方法、试剂及其应用
CN113959911A (zh) * 2020-07-20 2022-01-21 深圳迈瑞生物医疗电子股份有限公司 抗血小板聚集干扰的检测方法、试剂及其应用

Family Cites Families (11)

* Cited by examiner, † Cited by third party
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US2617198A (en) * 1945-06-13 1952-11-11 Better Packages Inc Pull-out measuring tape dispenser
DE927507C (de) * 1953-02-24 1955-05-09 Bayer Ag Verfahren zur Herstellung von Derivaten des 6-Oxy-2-aminobenzthiazols
GB808191A (en) * 1956-07-13 1959-01-28 Robert Ronald Davies New dyestuff intermediates
AR204835A1 (es) * 1973-07-18 1976-03-05 Scherico Ltd Procedimiento para preparar benzotiazol-2-carbamatos de etilo
US4006242A (en) * 1973-07-18 1977-02-01 Schering Corporation Certain benzothiazoles used in the treatment of helminthiasis
DK148476C (da) 1975-04-25 1985-12-16 Scherico Ltd Analogifremgangsmaade til fremstilling af methyl-6-n-propoxybenzothiazol-2-carbamat
JPS5221054A (en) * 1975-08-11 1977-02-17 Teijin Ltd Polyamide composition
DE2656468A1 (de) * 1976-12-14 1978-06-15 Boehringer Mannheim Gmbh N-(benzthiazol-2-yl)-oxamidsaeure- derivate und verfahren zu ihrer herstellung
DE2963316D1 (en) * 1978-01-18 1982-09-02 Hoechst Ag Process for the preparation of 2-amino-arylenothiazole compounds and their ring n-substituted derivatives
JPS5740492A (en) * 1980-08-22 1982-03-06 Yamanouchi Pharmaceut Co Ltd Novel 2-phenylimidazo 2,1-b benzothiazole derivative
US4581457A (en) * 1984-09-21 1986-04-08 American Home Products Corporation Heterocyclic sulfonamides

Also Published As

Publication number Publication date
NO882627D0 (no) 1988-06-15
DK328888D0 (da) 1988-06-16
JPS6479162A (en) 1989-03-24
ATE82276T1 (de) 1992-11-15
HUT47554A (en) 1989-03-28
AU1769988A (en) 1988-12-22
DE3875809D1 (de) 1992-12-17
SU1731051A3 (ru) 1992-04-30
EP0295656A1 (en) 1988-12-21
DE3875809T2 (de) 1993-04-15
ES2045017T3 (es) 1994-01-16
JP2793195B2 (ja) 1998-09-03
DD282686A5 (de) 1990-09-19
NO882627L (no) 1988-12-19
PT87747B (pt) 1992-10-30
NZ224946A (en) 1990-07-26
US4929623A (en) 1990-05-29
CN1030757A (zh) 1989-02-01
FI882692A (fi) 1988-12-18
FI91859C (fi) 1994-08-25
PT87747A (pt) 1988-07-01
HU205347B (en) 1992-04-28
KR890000451A (ko) 1989-03-14
NO170929B (no) 1992-09-21
CA1322369C (en) 1993-09-21
KR910005709B1 (ko) 1991-08-02
ZA884277B (en) 1989-03-29
NO170929C (no) 1993-01-06
AU610186B2 (en) 1991-05-16
DK328888A (da) 1988-12-18
EP0295656B1 (en) 1992-11-11
FI882692A0 (fi) 1988-06-07
FI91859B (fi) 1994-05-13
PH26553A (en) 1992-08-19

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