ATE103808T1 - N-(3,4-dimethoxycinnamoyl)-anthranilsaeure enthaltende arzneimittelzusammensetzungen. - Google Patents
N-(3,4-dimethoxycinnamoyl)-anthranilsaeure enthaltende arzneimittelzusammensetzungen.Info
- Publication number
- ATE103808T1 ATE103808T1 AT89311879T AT89311879T ATE103808T1 AT E103808 T1 ATE103808 T1 AT E103808T1 AT 89311879 T AT89311879 T AT 89311879T AT 89311879 T AT89311879 T AT 89311879T AT E103808 T1 ATE103808 T1 AT E103808T1
- Authority
- AT
- Austria
- Prior art keywords
- dimethoxycinnamoyl
- anthranilic acid
- composition
- compositions containing
- medicinal compositions
- Prior art date
Links
- 239000000203 mixture Substances 0.000 title abstract 4
- NZHGWWWHIYHZNX-UHFFFAOYSA-N 2-((3-(3,4-dimethoxyphenyl)-1-oxo-2-propenyl)amino)benzoic acid Chemical compound C1=C(OC)C(OC)=CC=C1C=CC(=O)NC1=CC=CC=C1C(O)=O NZHGWWWHIYHZNX-UHFFFAOYSA-N 0.000 title abstract 2
- 206010010744 Conjunctivitis allergic Diseases 0.000 abstract 1
- 206010039085 Rhinitis allergic Diseases 0.000 abstract 1
- 239000004480 active ingredient Substances 0.000 abstract 1
- 208000002205 allergic conjunctivitis Diseases 0.000 abstract 1
- 201000010105 allergic rhinitis Diseases 0.000 abstract 1
- 239000007864 aqueous solution Substances 0.000 abstract 1
- 208000024998 atopic conjunctivitis Diseases 0.000 abstract 1
- 150000007514 bases Chemical class 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 235000013855 polyvinylpyrrolidone Nutrition 0.000 abstract 1
- 229920000036 polyvinylpyrrolidone Polymers 0.000 abstract 1
- 239000001267 polyvinylpyrrolidone Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 239000004094 surface-active agent Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0048—Eye, e.g. artificial tears
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/14—Decongestants or antiallergics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/16—Otologicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
Landscapes
- Health & Medical Sciences (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Ophthalmology & Optometry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pulmonology (AREA)
- Immunology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP1085521A JPH07116029B2 (ja) | 1989-04-04 | 1989-04-04 | トラニラスト水溶液製剤 |
| EP89311879A EP0391002B1 (de) | 1989-04-04 | 1989-11-16 | N-(3,4-dimethoxycinnamoyl)-Anthranilsäure enthaltende Arzneimittelzusammensetzungen |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE103808T1 true ATE103808T1 (de) | 1994-04-15 |
Family
ID=13861211
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT89311879T ATE103808T1 (de) | 1989-04-04 | 1989-11-16 | N-(3,4-dimethoxycinnamoyl)-anthranilsaeure enthaltende arzneimittelzusammensetzungen. |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US5356620A (de) |
| EP (1) | EP0391002B1 (de) |
| JP (1) | JPH07116029B2 (de) |
| KR (1) | KR940002660B1 (de) |
| AT (1) | ATE103808T1 (de) |
| AU (1) | AU623191B2 (de) |
| CA (1) | CA2003190C (de) |
| DE (1) | DE68914438T2 (de) |
| DK (1) | DK555089A (de) |
| ES (1) | ES2063146T3 (de) |
| FI (1) | FI95773C (de) |
| NO (1) | NO176346C (de) |
Families Citing this family (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5897858A (en) | 1994-02-03 | 1999-04-27 | Schering-Plough Healthcare Products, Inc. | Nasal spray compositions exhibiting increased retention in the nasal cavity |
| US6239177B1 (en) * | 1996-02-07 | 2001-05-29 | Lead Chemical Co., Ltd. | Tranilast-containing preparation for external application and method of producing the same |
| JPH09278653A (ja) * | 1996-04-05 | 1997-10-28 | Santen Pharmaceut Co Ltd | 網膜疾患治療剤 |
| IL118657A0 (en) * | 1996-06-14 | 1996-10-16 | Arad Dorit | Inhibitors for picornavirus proteases |
| DE69720521T2 (de) * | 1996-09-28 | 2004-03-04 | Kissei Pharmaceutical Co., Ltd., Matsumoto | Hemmer der subepithelialen turbidität |
| BR9712308A (pt) * | 1996-10-14 | 1999-08-31 | Kissie Pharmaceutical Co Ltd | Inibidor de catarata secundária |
| IL131216A (en) * | 1997-02-14 | 2003-10-31 | Kissei Pharmaceutical | Drugs inhibiting progress of pterygium and postoperative recurrence of the same |
| NZ500300A (en) * | 1997-04-18 | 2001-01-26 | Kissei Pharmaceutical | Compositions containing N-(3,4-dimethoxycinnamoyl) anthranilic acid for the treatment of excessive proliferation of retinal pigment epithelial cells |
| IL122591A0 (en) | 1997-12-14 | 1998-06-15 | Arad Dorit | Pharmaceutical compositions comprising cystein protease inhibitors |
| US6274626B1 (en) | 1998-12-22 | 2001-08-14 | Bausch & Lomb Incorporated | Pheniramine-containing compositions and method for treating allergic responses |
| JP2001158750A (ja) * | 1999-12-02 | 2001-06-12 | Lion Corp | 眼科用組成物及び抗アレルギー薬の持続性向上方法 |
| JP4541504B2 (ja) * | 2000-06-14 | 2010-09-08 | 沢井製薬株式会社 | トラニラストまたはその薬理学的に許容される塩を有効成分として含有する安定な水溶液製剤 |
| AU2002234236A1 (en) * | 2001-01-10 | 2002-07-24 | Smithkline Beecham Corporation | Process and product |
| JP2011225626A (ja) * | 2001-02-01 | 2011-11-10 | Rohto Pharmaceutical Co Ltd | 点眼剤 |
| JP2002363075A (ja) * | 2001-06-05 | 2002-12-18 | Kao Corp | 高血圧症予防・治療剤 |
| DE10254872A1 (de) | 2002-11-25 | 2004-06-03 | Symrise Gmbh & Co. Kg | Anthranilsäureamide und deren Derivate als kosmetische und pharmazeutische Wirkstoffe |
| JP2004189731A (ja) * | 2002-11-26 | 2004-07-08 | Taisho Pharmaceut Co Ltd | 点鼻剤 |
| US20050106230A1 (en) * | 2003-11-17 | 2005-05-19 | Young Janel E. | Drug-enhanced adhesion prevention |
| JP2006306765A (ja) * | 2005-04-27 | 2006-11-09 | Nippon Tenganyaku Kenkyusho:Kk | トラニラスト水性点眼液 |
| KR101704953B1 (ko) * | 2006-07-05 | 2017-02-08 | 피브로테크 세라퓨틱 피티와이 엘티디 | 치료 화합물 |
| KR20160017139A (ko) * | 2007-12-21 | 2016-02-15 | 피브로테크 세라퓨틱 피티와이 엘티디 | 항섬유증 제제의 할로겐화 유사체 |
| US9062076B2 (en) | 2009-10-22 | 2015-06-23 | Fibrotech Therapeutics Pty Ltd | Fused ring analogues of anti-fibrotic agents |
| MX2013000578A (es) * | 2010-07-21 | 2013-02-21 | Alcon Res Ltd | Composicion farmaceutica con caracteristicas de solubilidad incrementadas. |
| JP7191515B2 (ja) * | 2017-01-17 | 2022-12-19 | ロート製薬株式会社 | 眼科組成物 |
| SG11201907139UA (en) | 2017-02-03 | 2019-09-27 | Certa Therapeutics Pty Ltd | Anti-fibrotic compounds |
| JP6427244B2 (ja) * | 2017-10-03 | 2018-11-21 | ロート製薬株式会社 | 点眼剤 |
| TWI651095B (zh) * | 2017-10-18 | 2019-02-21 | 晶碩光學股份有限公司 | 具有抗敏舒緩效果的眼用產品 |
| CN109718376B (zh) * | 2017-10-27 | 2022-01-25 | 晶硕光学股份有限公司 | 具有抗敏舒缓效果的眼用产品 |
| EP3837238B1 (de) * | 2018-08-14 | 2024-06-12 | Nuformix Technologies Limited | Kristalline tranilastsalze und ihre pharmazeutische verwendung |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR1296518A (fr) * | 1959-04-25 | 1962-06-22 | Véhicule liquide pour collyre | |
| US3856919A (en) * | 1970-06-08 | 1974-12-24 | Burton Parsons Chemicals Inc | Ophthalmic solution |
| US4070484A (en) * | 1973-01-18 | 1978-01-24 | Kissei Pharmaceutical Co., Ltd. | Antiallergic composition containing aromatic carboxylic amide derivatives and method of using the same |
| US4029817A (en) * | 1973-09-24 | 1977-06-14 | Allergan Pharmaceuticals | Soft contact lens preserving solutions |
| JPS6144811A (ja) * | 1984-08-10 | 1986-03-04 | Ss Pharmaceut Co Ltd | 徐放性ジクロフエナクナトリウム製剤 |
| US4666929A (en) * | 1985-04-10 | 1987-05-19 | Shiseido Company Ltd. | Anthranilic acid ester derivatives and antiinflammatory and analgetic external preparations containing the same |
| CA1291036C (en) * | 1986-04-23 | 1991-10-22 | Edwin I. Stoltz | Nasal administration of drugs |
| WO1988004922A1 (fr) * | 1986-12-25 | 1988-07-14 | Teysan Pharmaceuticals Co., Ltd. | Granule a dissolution lente et granule composite a effet persistant prepare a partir du premier granule |
-
1989
- 1989-04-04 JP JP1085521A patent/JPH07116029B2/ja not_active Expired - Lifetime
- 1989-11-03 AU AU44384/89A patent/AU623191B2/en not_active Ceased
- 1989-11-07 DK DK555089A patent/DK555089A/da not_active Application Discontinuation
- 1989-11-11 KR KR1019890016341A patent/KR940002660B1/ko not_active Expired - Lifetime
- 1989-11-16 EP EP89311879A patent/EP0391002B1/de not_active Expired - Lifetime
- 1989-11-16 ES ES89311879T patent/ES2063146T3/es not_active Expired - Lifetime
- 1989-11-16 AT AT89311879T patent/ATE103808T1/de not_active IP Right Cessation
- 1989-11-16 DE DE68914438T patent/DE68914438T2/de not_active Expired - Fee Related
- 1989-11-17 NO NO894602A patent/NO176346C/no unknown
- 1989-11-17 FI FI895492A patent/FI95773C/fi not_active IP Right Cessation
- 1989-11-17 CA CA002003190A patent/CA2003190C/en not_active Expired - Fee Related
-
1991
- 1991-04-03 US US07/680,786 patent/US5356620A/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| JPH07116029B2 (ja) | 1995-12-13 |
| DK555089A (da) | 1990-10-05 |
| DE68914438D1 (de) | 1994-05-11 |
| EP0391002B1 (de) | 1994-04-06 |
| DK555089D0 (da) | 1989-11-07 |
| NO176346C (no) | 1995-03-22 |
| FI95773B (fi) | 1995-12-15 |
| CA2003190C (en) | 1997-04-29 |
| KR900015722A (ko) | 1990-11-10 |
| NO894602L (no) | 1990-10-05 |
| JPH02264716A (ja) | 1990-10-29 |
| FI895492A0 (fi) | 1989-11-17 |
| NO176346B (no) | 1994-12-12 |
| AU4438489A (en) | 1990-10-11 |
| NO894602D0 (no) | 1989-11-17 |
| EP0391002A3 (de) | 1991-06-26 |
| HK1003780A1 (en) | 1998-11-06 |
| KR940002660B1 (ko) | 1994-03-28 |
| CA2003190A1 (en) | 1990-10-04 |
| DE68914438T2 (de) | 1994-07-28 |
| ES2063146T3 (es) | 1995-01-01 |
| US5356620A (en) | 1994-10-18 |
| EP0391002A2 (de) | 1990-10-10 |
| AU623191B2 (en) | 1992-05-07 |
| FI95773C (fi) | 1996-03-25 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification | ||
| REN | Ceased due to non-payment of the annual fee |