KR900015722A - N-(3,4-디메톡시신나모일) 안트라닐산을 함유하는 약제 조성물 - Google Patents

N-(3,4-디메톡시신나모일) 안트라닐산을 함유하는 약제 조성물 Download PDF

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KR900015722A
KR900015722A KR1019890016341A KR890016341A KR900015722A KR 900015722 A KR900015722 A KR 900015722A KR 1019890016341 A KR1019890016341 A KR 1019890016341A KR 890016341 A KR890016341 A KR 890016341A KR 900015722 A KR900015722 A KR 900015722A
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pharmaceutical composition
dimethoxycinnamoyl
anthranilic acid
composition according
aqueous solution
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KR1019890016341A
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KR940002660B1 (ko
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도끼히꼬 야마모도
다이헤이 시바자끼
유끼요시 아지사와
료오지 야마모도
유끼히꼬 기노시다
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깃세이 야꾸힝 고오교오 가부시끼가이샤
가부시끼가이샤 니혼 덴간야꾸 겐꾸우쇼
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Application filed by 깃세이 야꾸힝 고오교오 가부시끼가이샤, 가부시끼가이샤 니혼 덴간야꾸 겐꾸우쇼 filed Critical 깃세이 야꾸힝 고오교오 가부시끼가이샤
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/14—Decongestants or antiallergics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/16—Otologicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents

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  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Ophthalmology & Optometry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

내용 없음.

Description

N-(3,4-디메톡시신나모일) 안트라닐산을 함유하는 약제 조성물
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음

Claims (7)

  1. (a) N-(3,4-디메톡시신나모일) 안트라닐산 또는 약제상 허용되는 그의 염, (b) 폴리비닐피롤리돈, (c) 염기성 화합물, 및 (d) 계면활성제를 함유하며, 6.5 내지 8.5범위의 pH를 가진 수용액으로 되어 있는 것을 특징으로 하는 알레르기성 질환의 국소치료용 약제조성물.
  2. 제1항에 있어서, 수용액의 눈치료제인 것을 특징으로 하는 약제조성물.
  3. 제1항에 있어서, 수용액이 코치료제인 것을 특징으로 하는 약제조성물.
  4. (a) 조성물 용적기준으로, 0.1 내지 2중량%의 N-(3,4-디메톡시신나모일) 안트라닐산 또는 약제상 허용되는그의 염, (b) N-(3,4-디메톡시신나모일) 안트라닐산 성분의 중량단위당 4 내지 8중량 단위의 폴리비닐피폴리돈, (c) N-(3,4-디메톡시신나모일) 안트라닐산 성분의 중량단위당 0.7 내지 3중량 단위의 염기성 화합물, 및 (d) 조성물 용적기준으로 0.025 내지 0.1중량%의 계면활성제를 함유하며, 6.5 내지 8.5범위의 pH를 가진 수용액으로 되어 있는 것을 특징으로하는 알레르기성 결막염 또는 알레르기성 비염의 국소치료용 약제조성물.
  5. 제4항에 있어서, 염기성 화합물이 붕산나트륨 또는 3염기성 인산나트륨인 것을 특징으로 하는 약제조성물.
  6. 제4항에 있어서, 계면활성제가 0.025 내지 0.075중량%의 폴리옥시에틸렌 소르비탄 모노올레이트인 것을 특징으로 하는 약제조성물.
  7. 알레르기 반응부위에 청구범위 제4항에 의한 수성약제 조성물을 국소적으로 투여하는 것으로 되어 있는 것을 특징으로 하는 알레르기성 결막염 또는 알레르기성 비염을 치료하는 방법.
    ※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
KR1019890016341A 1989-04-04 1989-11-11 N-(3,4-디메톡시신나모일) 안트라닐산을 함유하는 약제조성물 KR940002660B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP1085521A JPH07116029B2 (ja) 1989-04-04 1989-04-04 トラニラスト水溶液製剤
JP89-85521 1989-04-04
JP1-85521 1989-04-04

Publications (2)

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KR900015722A true KR900015722A (ko) 1990-11-10
KR940002660B1 KR940002660B1 (ko) 1994-03-28

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ID=13861211

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KR1019890016341A KR940002660B1 (ko) 1989-04-04 1989-11-11 N-(3,4-디메톡시신나모일) 안트라닐산을 함유하는 약제조성물

Country Status (13)

Country Link
US (1) US5356620A (ko)
EP (1) EP0391002B1 (ko)
JP (1) JPH07116029B2 (ko)
KR (1) KR940002660B1 (ko)
AT (1) ATE103808T1 (ko)
AU (1) AU623191B2 (ko)
CA (1) CA2003190C (ko)
DE (1) DE68914438T2 (ko)
DK (1) DK555089A (ko)
ES (1) ES2063146T3 (ko)
FI (1) FI95773C (ko)
HK (1) HK1003780A1 (ko)
NO (1) NO176346C (ko)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5897858A (en) 1994-02-03 1999-04-27 Schering-Plough Healthcare Products, Inc. Nasal spray compositions exhibiting increased retention in the nasal cavity
JP4154621B2 (ja) * 1996-02-07 2008-09-24 リードケミカル株式会社 トラニラスト含有外用製剤及びその製造方法
JPH09278653A (ja) * 1996-04-05 1997-10-28 Santen Pharmaceut Co Ltd 網膜疾患治療剤
IL118657A0 (en) * 1996-06-14 1996-10-16 Arad Dorit Inhibitors for picornavirus proteases
AU4397197A (en) * 1996-09-28 1998-04-17 Kissei Pharmaceutical Co. Ltd. Subepithelial turbidity inhibitor
IL129421A0 (en) * 1996-10-14 2000-02-17 Kissei Pharmaceutical Secondary cataract inhibitor
ES2198692T3 (es) * 1997-02-14 2004-02-01 Kissei Pharmaceutical Co., Ltd. Medicamentos que inhiben el progreso de pterigion y su frecuencia post-operatoria.
RU2207852C2 (ru) * 1997-04-18 2003-07-10 Киссеи Фармасьютикал Ко., Лтд. Средства для предотвращения или лечения болезней, связанных с чрезмерной пролиферацией эпителиальных пигментных клеток сетчатки
IL122591A0 (en) 1997-12-14 1998-06-15 Arad Dorit Pharmaceutical compositions comprising cystein protease inhibitors
US6274626B1 (en) * 1998-12-22 2001-08-14 Bausch & Lomb Incorporated Pheniramine-containing compositions and method for treating allergic responses
JP2001158750A (ja) * 1999-12-02 2001-06-12 Lion Corp 眼科用組成物及び抗アレルギー薬の持続性向上方法
JP4541504B2 (ja) * 2000-06-14 2010-09-08 沢井製薬株式会社 トラニラストまたはその薬理学的に許容される塩を有効成分として含有する安定な水溶液製剤
AU2002234236A1 (en) * 2001-01-10 2002-07-24 Smithkline Beecham Corporation Process and product
JP2011225626A (ja) * 2001-02-01 2011-11-10 Rohto Pharmaceutical Co Ltd 点眼剤
JP2002363075A (ja) * 2001-06-05 2002-12-18 Kao Corp 高血圧症予防・治療剤
DE10254872A1 (de) * 2002-11-25 2004-06-03 Symrise Gmbh & Co. Kg Anthranilsäureamide und deren Derivate als kosmetische und pharmazeutische Wirkstoffe
JP2004189731A (ja) * 2002-11-26 2004-07-08 Taisho Pharmaceut Co Ltd 点鼻剤
US20050106230A1 (en) * 2003-11-17 2005-05-19 Young Janel E. Drug-enhanced adhesion prevention
JP2006306765A (ja) * 2005-04-27 2006-11-09 Nippon Tenganyaku Kenkyusho:Kk トラニラスト水性点眼液
NZ574028A (en) 2006-07-05 2010-10-29 Fibrotech Therapeutics Pty Ltd Tranilast analogues (substituted cinnamoyl anthranilate compounds) for treatment of conditions associated with firbrosis
EP3045170B1 (en) * 2007-12-21 2018-07-04 Fibrotech Therapeutics PTY LTD Halogenated analogues of anti-fibrotic agents
IN2012DN03312A (ko) 2009-10-22 2015-10-23 Fibrotech Therapeutics Pty Ltd
KR20130094293A (ko) * 2010-07-21 2013-08-23 알콘 리서치, 리미티드 향상된 용해도 특성들을 갖는 약학 조성물
JP7191515B2 (ja) * 2017-01-17 2022-12-19 ロート製薬株式会社 眼科組成物
MX2019009235A (es) 2017-02-03 2019-12-11 Certa Therapeutics Pty Ltd Compuestos antifibroticos.
JP6427244B2 (ja) * 2017-10-03 2018-11-21 ロート製薬株式会社 点眼剤
TWI651095B (zh) * 2017-10-18 2019-02-21 晶碩光學股份有限公司 具有抗敏舒緩效果的眼用產品
CN109718376B (zh) * 2017-10-27 2022-01-25 晶硕光学股份有限公司 具有抗敏舒缓效果的眼用产品
EP3837238B1 (en) * 2018-08-14 2024-06-12 Nuformix Technologies Limited Crystalline tranilast salts and their pharmaceutical use

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1296518A (fr) * 1959-04-25 1962-06-22 Véhicule liquide pour collyre
US3856919A (en) * 1970-06-08 1974-12-24 Burton Parsons Chemicals Inc Ophthalmic solution
US4070484A (en) * 1973-01-18 1978-01-24 Kissei Pharmaceutical Co., Ltd. Antiallergic composition containing aromatic carboxylic amide derivatives and method of using the same
US4029817A (en) * 1973-09-24 1977-06-14 Allergan Pharmaceuticals Soft contact lens preserving solutions
JPS6144811A (ja) * 1984-08-10 1986-03-04 Ss Pharmaceut Co Ltd 徐放性ジクロフエナクナトリウム製剤
US4666929A (en) * 1985-04-10 1987-05-19 Shiseido Company Ltd. Anthranilic acid ester derivatives and antiinflammatory and analgetic external preparations containing the same
CA1291036C (en) * 1986-04-23 1991-10-22 Edwin I. Stoltz Nasal administration of drugs
KR910002669B1 (ko) * 1986-12-25 1991-05-03 데이산세이야꾸 가부시끼가이샤 서방성 과립 및 그를 함유하는 지속성 복합과립
JPH01294620A (ja) * 1988-05-19 1989-11-28 Kissei Pharmaceut Co Ltd 水溶液製剤およびその製造方法

Also Published As

Publication number Publication date
EP0391002B1 (en) 1994-04-06
EP0391002A3 (en) 1991-06-26
FI95773C (fi) 1996-03-25
HK1003780A1 (en) 1998-11-06
CA2003190C (en) 1997-04-29
ATE103808T1 (de) 1994-04-15
FI895492A0 (fi) 1989-11-17
DK555089A (da) 1990-10-05
NO176346B (no) 1994-12-12
DE68914438T2 (de) 1994-07-28
NO894602L (no) 1990-10-05
JPH07116029B2 (ja) 1995-12-13
AU4438489A (en) 1990-10-11
ES2063146T3 (es) 1995-01-01
AU623191B2 (en) 1992-05-07
US5356620A (en) 1994-10-18
NO894602D0 (no) 1989-11-17
NO176346C (no) 1995-03-22
FI95773B (fi) 1995-12-15
CA2003190A1 (en) 1990-10-04
KR940002660B1 (ko) 1994-03-28
EP0391002A2 (en) 1990-10-10
JPH02264716A (ja) 1990-10-29
DK555089D0 (da) 1989-11-07
DE68914438D1 (de) 1994-05-11

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