ATE69049T1 - Chinazolin-derivat, verfahren zu dessen herstellung und mittel zur behandlung von cerebraler disfunktion als aktiver inhaltsstoff. - Google Patents
Chinazolin-derivat, verfahren zu dessen herstellung und mittel zur behandlung von cerebraler disfunktion als aktiver inhaltsstoff.Info
- Publication number
- ATE69049T1 ATE69049T1 AT87118691T AT87118691T ATE69049T1 AT E69049 T1 ATE69049 T1 AT E69049T1 AT 87118691 T AT87118691 T AT 87118691T AT 87118691 T AT87118691 T AT 87118691T AT E69049 T1 ATE69049 T1 AT E69049T1
- Authority
- AT
- Austria
- Prior art keywords
- production
- agent
- cerebrae
- disfunction
- treatment
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 2
- 239000004480 active ingredient Substances 0.000 title 1
- JWVCLYRUEFBMGU-UHFFFAOYSA-N quinazoline Chemical class N1=CN=CC2=CC=CC=C21 JWVCLYRUEFBMGU-UHFFFAOYSA-N 0.000 title 1
- 208000012902 Nervous system disease Diseases 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- -1 quinazoline compound Chemical class 0.000 abstract 1
- 150000003246 quinazolines Chemical class 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
- C07D239/72—Quinazolines; Hydrogenated quinazolines
- C07D239/95—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in positions 2 and 4
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Psychiatry (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Hospice & Palliative Care (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP62200510A JPS6442472A (en) | 1987-08-10 | 1987-08-10 | Quinazoline derivative, production thereof and brain function disorder improving agent containing said derivative as active ingredient |
| EP87118691A EP0302967B1 (de) | 1987-08-10 | 1987-12-16 | Chinazolin-Derivat, Verfahren zu dessen Herstellung und Mittel zur Behandlung von cerebraler Disfunktion als aktiver Inhaltsstoff |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE69049T1 true ATE69049T1 (de) | 1991-11-15 |
Family
ID=16425510
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT87118691T ATE69049T1 (de) | 1987-08-10 | 1987-12-16 | Chinazolin-derivat, verfahren zu dessen herstellung und mittel zur behandlung von cerebraler disfunktion als aktiver inhaltsstoff. |
Country Status (6)
| Country | Link |
|---|---|
| EP (1) | EP0302967B1 (de) |
| JP (1) | JPS6442472A (de) |
| AT (1) | ATE69049T1 (de) |
| DE (1) | DE3774273D1 (de) |
| ES (1) | ES2044908T3 (de) |
| GR (1) | GR3003232T3 (de) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5041443A (en) * | 1989-02-21 | 1991-08-20 | Dainippon Pharmaceutical Co., Ltd. | Medicament for treating cerebral insufficiency diseases, novel 2-(1-piperazinyl)-4-phenylcycloalkanopyrimidine derivatives, and process for the production thereof |
| US5185338A (en) * | 1989-02-21 | 1993-02-09 | Dainippon Pharmaceutical Co., Ltd. | Medicament for treating cerebral insufficiency diseases, novel 2-(1-piperazinyl)-4-phenylcycloalkanopyrimidine derivatives, and process for the production thereof |
| HU214331B (hu) * | 1992-06-17 | 1998-03-02 | Gyógyszerkutató Intézet Kft. | Eljárás piperazin- és homopiperazinszármazékok és ezeket tartalmazó gyógyszerkészítmények előállítására |
| US7019012B2 (en) | 2000-12-20 | 2006-03-28 | Boehringer Ingelheim International Pharma Gmbh & Co. Kg | Quinazoline derivatives and pharmaceutical compositions containing them |
| DK1557414T3 (da) | 2002-10-01 | 2012-05-29 | Mitsubishi Tanabe Pharma Corp | IsoquinoIin-forbindelser og medicinsk anvendelse deraf |
| DE10349113A1 (de) | 2003-10-17 | 2005-05-12 | Boehringer Ingelheim Pharma | Verfahren zur Herstellung von Aminocrotonylverbindungen |
| JP5688877B2 (ja) | 2005-11-11 | 2015-03-25 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | 癌疾患の治療用キナゾリン誘導体 |
| DK2068880T3 (da) | 2006-09-18 | 2012-07-23 | Boehringer Ingelheim Int | Fremgangsmåde til behandling af cancer, der huser EGFR-mutationer |
| HUE044629T2 (hu) | 2009-07-06 | 2019-11-28 | Boehringer Ingelheim Int | Eljárás BIBW2992, annak sói, valamint e hatóanyagot tartalmazó szilárd gyógyászati készítmények szárítására |
| US9242965B2 (en) | 2013-12-31 | 2016-01-26 | Boehringer Ingelheim International Gmbh | Process for the manufacture of (E)-4-N,N-dialkylamino crotonic acid in HX salt form and use thereof for synthesis of EGFR tyrosine kinase inhibitors |
| DE102015012049A1 (de) * | 2015-09-15 | 2017-03-16 | Merck Patent Gmbh | Verbindungen als ASIC-Inhibitoren und deren Verwendungen |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1062357A (en) * | 1965-03-23 | 1967-03-22 | Pfizer & Co C | Quinazolone derivatives |
-
1987
- 1987-08-10 JP JP62200510A patent/JPS6442472A/ja active Pending
- 1987-12-16 EP EP87118691A patent/EP0302967B1/de not_active Expired - Lifetime
- 1987-12-16 AT AT87118691T patent/ATE69049T1/de not_active IP Right Cessation
- 1987-12-16 ES ES87118691T patent/ES2044908T3/es not_active Expired - Lifetime
- 1987-12-16 DE DE8787118691T patent/DE3774273D1/de not_active Expired - Fee Related
-
1991
- 1991-11-28 GR GR91401837T patent/GR3003232T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| ES2044908T3 (es) | 1994-01-16 |
| JPS6442472A (en) | 1989-02-14 |
| EP0302967B1 (de) | 1991-10-30 |
| EP0302967A2 (de) | 1989-02-15 |
| EP0302967A3 (en) | 1989-05-03 |
| DE3774273D1 (de) | 1991-12-05 |
| GR3003232T3 (en) | 1993-02-17 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification | ||
| REN | Ceased due to non-payment of the annual fee |