NO148280C - Fremgangsmaate for fremstilling av tetracyklinpreparater - Google Patents

Fremgangsmaate for fremstilling av tetracyklinpreparater

Info

Publication number
NO148280C
NO148280C NO781457A NO781457A NO148280C NO 148280 C NO148280 C NO 148280C NO 781457 A NO781457 A NO 781457A NO 781457 A NO781457 A NO 781457A NO 148280 C NO148280 C NO 148280C
Authority
NO
Norway
Prior art keywords
procedure
preparation
tetracycline
preparations
tetracycline preparations
Prior art date
Application number
NO781457A
Other languages
English (en)
Other versions
NO781457L (no
NO148280B (no
Inventor
William Wellesley Armstrong
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of NO781457L publication Critical patent/NO781457L/no
Publication of NO148280B publication Critical patent/NO148280B/no
Publication of NO148280C publication Critical patent/NO148280C/no

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/65—Tetracyclines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/22—Heterocyclic compounds, e.g. ascorbic acid, tocopherol or pyrrolidones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Inorganic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Hydrogenated Pyridines (AREA)
NO781457A 1977-04-27 1978-04-26 Fremgangsmaate for fremstilling av tetracyklinpreparater NO148280C (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/791,627 US4126680A (en) 1977-04-27 1977-04-27 Tetracycline antibiotic compositions

Publications (3)

Publication Number Publication Date
NO781457L NO781457L (no) 1978-10-30
NO148280B NO148280B (no) 1983-06-06
NO148280C true NO148280C (no) 1983-09-21

Family

ID=25154289

Family Applications (1)

Application Number Title Priority Date Filing Date
NO781457A NO148280C (no) 1977-04-27 1978-04-26 Fremgangsmaate for fremstilling av tetracyklinpreparater

Country Status (38)

Country Link
US (1) US4126680A (no)
JP (1) JPS53136514A (no)
AR (1) AR217844A1 (no)
AT (1) AT360148B (no)
AU (1) AU503139B1 (no)
BE (1) BE866419A (no)
BG (1) BG47943A3 (no)
CA (1) CA1100875A (no)
CH (1) CH630260A5 (no)
CS (1) CS199527B2 (no)
DD (1) DD135445A5 (no)
DE (1) DE2817335C3 (no)
DK (1) DK155977C (no)
EG (1) EG14348A (no)
ES (1) ES468749A1 (no)
FI (1) FI781300A (no)
FR (1) FR2388561A1 (no)
GB (1) GB1563478A (no)
GR (1) GR70062B (no)
HU (1) HU179050B (no)
IE (1) IE47049B1 (no)
IL (1) IL54581A0 (no)
IN (1) IN148197B (no)
IT (1) IT1094557B (no)
LU (1) LU79547A1 (no)
MX (1) MX6087E (no)
NL (1) NL7804455A (no)
NO (1) NO148280C (no)
NZ (1) NZ187046A (no)
OA (1) OA05949A (no)
PH (1) PH12962A (no)
PL (1) PL110459B1 (no)
PT (1) PT67895B (no)
RO (2) RO77953A (no)
SE (1) SE443507B (no)
YU (1) YU87178A (no)
ZA (1) ZA782400B (no)
ZM (1) ZM3878A1 (no)

Families Citing this family (80)

* Cited by examiner, † Cited by third party
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US4399127A (en) * 1980-04-10 1983-08-16 Diamond Shamrock Corporation Injectable oxytetracycline compositions
US4386083A (en) * 1980-04-10 1983-05-31 Walter Hacke Injectable oxytetracycline compositions
US5589470A (en) * 1990-02-26 1996-12-31 Trustees Of Tufts College Reducing tetracycline resistance in living cells
US4806529A (en) * 1982-11-18 1989-02-21 Trustees Of Tufts College, Tufts University Tetracycline activity enhancement
US5064821A (en) * 1982-11-18 1991-11-12 Trustees Of Tufts College Method and compositions for overcoming tetracycline resistance within living cells
US4769232A (en) * 1984-03-22 1988-09-06 Pfizer Inc. Parenteral formulations of indolmycin
US6756365B2 (en) * 1991-11-06 2004-06-29 Trustees Of Tufts College Reducing tetracycline resistance in living cells
EP0621033A1 (en) * 1993-04-20 1994-10-26 Nostras S.A. Antibiotic composition containing oxytetracycline and glycofurol
US6849615B2 (en) 1999-09-14 2005-02-01 Paratek Pharmaceuticals, Inc. 13-substituted methacycline compounds
DE60027465T2 (de) 1999-09-14 2007-02-01 The Trustees Of Tufts College, Medford Verfahren zur herstellung von substituierten tetracyclinen mit hilfe von auf übergangsmetalle basierten chemien
US8106225B2 (en) * 1999-09-14 2012-01-31 Trustees Of Tufts College Methods of preparing substituted tetracyclines with transition metal-based chemistries
US6500812B2 (en) 1999-09-14 2002-12-31 Paratek Pharmaceuticals, Inc. 13-substituted methacycline compounds
JP2003523963A (ja) 2000-01-24 2003-08-12 トラスティーズ・オブ・タフツ・カレッジ クリプトスポリジウム・パルヴム関連疾患の治療のためのテトラサイクリン化合物
BR0109725A (pt) * 2000-03-31 2003-02-04 Tufts College Composto de tetraciclina substituìdo, método para tratar um estado responsivo a tetraciclina em um mamìfero, composição farmacêutica, método para sintetizar um composto de tetraciclina 7- ou 9-substituìdo, e, intermediário reativo
AU2001259701A1 (en) 2000-05-15 2001-11-26 Paratek Pharmaceuticals, Inc 7-substituted fused ring tetracycline compounds
AU2001268475A1 (en) 2000-06-16 2002-01-02 Trustees Of Tufts College 7-phenyl-substituted tetracycline compounds
US20040224927A1 (en) 2000-06-16 2004-11-11 Trustees Of Tufts College 7-N-substituted phenyl tetracycline compounds
US20020132798A1 (en) * 2000-06-16 2002-09-19 Nelson Mark L. 7-phenyl-substituted tetracycline compounds
EP1661883B1 (en) 2000-07-07 2010-04-28 Trustees Of Tufts College 13-substituted methacycline compounds
DE60144375D1 (de) 2000-07-07 2011-05-19 Trustees Of Tufts College Medford 7-, 8- und 9-substitutierte tetracyclinverbindungen
US20050143353A1 (en) * 2000-07-07 2005-06-30 Paratek Pharmaceuticals, Inc. 13-Substituted methacycline compounds
WO2002004406A2 (en) 2000-07-07 2002-01-17 Trustees Of Tufts College 9-substituted minocycline compounds
US7094806B2 (en) 2000-07-07 2006-08-22 Trustees Of Tufts College 7, 8 and 9-substituted tetracycline compounds
HUP0301163A3 (en) 2000-07-07 2008-08-28 Tufts College 7-substituted tetracycline dervatives, pharmaceutical compositions containing them and their use
AU2002250331A1 (en) 2001-03-13 2002-09-24 Paratek Pharmaceuticals, Inc. 7-pyrollyl tetracycline compounds and methods of use thereof
CZ20032780A3 (cs) 2001-03-13 2004-01-14 Paratek Pharmaceuticals, Inc. 7,9- Substituované tetracyklinové sloučeniny
US7553828B2 (en) 2001-03-13 2009-06-30 Paratek Pharmaceuticals, Inc. 9-aminomethyl substituted minocycline compounds
CA2457234A1 (en) 2001-03-14 2002-09-19 Mark L. Nelson Substituted tetracycline compounds as antifungal agents
WO2002072031A2 (en) 2001-03-14 2002-09-19 Paratek Pharmaceuticals, Inc. Substituted tetracycline compounds as synergistic antifungal agents
US8088820B2 (en) * 2001-04-24 2012-01-03 Paratek Pharmaceuticals, Inc. Substituted tetracycline compounds for the treatment of malaria
EP1399414B1 (en) 2001-04-24 2010-01-13 Paratek Pharmaceuticals, Inc. Substituted tetracycline compounds for the treatment of malaria
EP2322501B1 (en) 2002-01-08 2015-08-05 Paratek Pharmaceuticals, Inc. 4-dedimethylamino tetracycline compounds
KR101093842B1 (ko) 2002-03-08 2011-12-13 파라테크 파마슈티컬스, 인크. 아미노-메틸 치환된 테트라시클린 화합물
CN1653037A (zh) 2002-03-21 2005-08-10 帕拉特克药品公司 取代的四环素化合物
KR101089429B1 (ko) 2002-07-12 2011-12-07 파라테크 파마슈티컬스, 인크. 3, 10, 및 12ａ 치환된 테트라시클린 화합물
WO2004038001A2 (en) 2002-10-24 2004-05-06 Paratek Pharmaceuticals, Inc. Substituted tetracycline compounds for the treatment of malaria
EP1656341A1 (en) 2003-07-09 2006-05-17 Paratek Pharmaceuticals, Inc. Prodrugs of 9-aminomethyl tetracycline compounds
EA201001081A1 (ru) 2003-07-09 2011-02-28 Пэрэтек Фамэсьютикэлс, Инк. Соединения тетрациклина, фармацевтическая композиция и способ лечения чувствительного к тетрациклину состояния у субъекта
NZ544826A (en) * 2003-07-25 2008-07-31 Warner Chilcott Co Inc A doxycycline metal complex in a solid dosage form
EP1716101A1 (en) * 2004-01-15 2006-11-02 Paratek Pharmaceuticals, Inc. Aromatic a-ring derivatives of tetracycline compounds
TWI261038B (en) * 2004-08-11 2006-09-01 Bo-Cheng Chen Bicycle gear-shifting handgrip
EP1805134B1 (en) 2004-10-25 2012-06-20 Paratek Pharmaceuticals, Inc. 4-aminotetracyclines and methods of use thereof
JP2008518035A (ja) 2004-10-25 2008-05-29 パラテック ファーマシューティカルズ インコーポレイテッド 置換テトラサイクリン化合物
EP1848685A1 (en) 2005-02-04 2007-10-31 Paratek Pharmaceuticals, Inc. 11a, 12-derivatives of tetracycline compounds
US9192615B2 (en) 2008-08-06 2015-11-24 Medicis Pharmaceutical Corporation Method for the treatment of acne and certain dosage forms thereof
US7544373B2 (en) * 2007-04-02 2009-06-09 Medicis Pharmaceutical Corporation Minocycline oral dosage forms for the treatment of acne
US8722650B1 (en) 2005-06-24 2014-05-13 Medicis Pharmaceutical Corporation Extended-release minocycline dosage forms
US20080241235A1 (en) * 2007-04-02 2008-10-02 Medicis Pharmaceutical Corporation Minocycline oral dosage forms for the treatment of acne
US8252776B2 (en) 2007-04-02 2012-08-28 Medicis Pharmaceutical Corporation Minocycline oral dosage forms for the treatment of acne
US20080242642A1 (en) * 2007-04-02 2008-10-02 Medicis Pharmaceutical Corporation Minocycline oral dosage forms for the treatment of acne
US7919483B2 (en) * 2005-06-24 2011-04-05 Medicis Pharmaceutical Corporation Method for the treatment of acne
US7541347B2 (en) * 2007-04-02 2009-06-02 Medicis Pharmaceutical Coropration Minocycline oral dosage forms for the treatment of acne
EP1991236A2 (en) * 2006-01-24 2008-11-19 Paratek Pharmaceuticals, Inc. Methods of increasing oral bioavailability of tetracyclines
EP2007713A2 (en) * 2006-04-17 2008-12-31 Teva Pharmaceutical Industries Ltd Isolation of tetracycline derivatives
US8198470B2 (en) * 2006-04-24 2012-06-12 Teva Pharmaceutical Industries Ltd. Crystalline form II of tigecycline and processes for preparation thereof
DK2016045T3 (en) * 2006-04-24 2015-02-02 Teva Pharma TIGECYCLIN CRYSTAL FORM AND PROCEDURES FOR PREPARING IT
US20080118979A1 (en) * 2006-05-15 2008-05-22 Paratek Pharmaceuticals, Inc. Methods of regulating expression of genes or of gene products using substituted tetracycline compounds
ES2315123B1 (es) * 2006-09-25 2009-12-30 Divasa-Farmavic, S.A. Composiciones farmaceuticas estables de tetraciclinas en solucion, procedimiento para su obtencion y sus usos.
US8440646B1 (en) 2006-10-11 2013-05-14 Paratek Pharmaceuticals, Inc. Substituted tetracycline compounds for treatment of Bacillus anthracis infections
CA2673466C (en) 2006-12-21 2016-06-14 Paratek Pharmaceuticals, Inc. Substituted tetracycline compounds
LT2120963T (lt) 2006-12-21 2019-01-10 Paratek Pharmaceuticals, Inc. Pakeistieji tetraciklino junginiai uždegiminių odos ligų gydymui
AU2012230089B2 (en) * 2007-03-23 2013-11-21 Molecular Research Center, Inc. Anti-inflammatory compositions comprising tetracyclines and use thereof in therapy
CN101678108A (zh) * 2007-03-23 2010-03-24 分子研究中心公司 包含四环素类的抗炎组合物及其用途
US20080241197A1 (en) * 2007-04-02 2008-10-02 Medicis Pharmaceutical Corporation Minocycline dosage forms for the treatment of acne
AU2008239606A1 (en) * 2007-04-12 2008-10-23 Paratek Pharmaceuticals, Inc. Methods for treating spinal muscular atrophy using tetracycline compounds
AU2008246119A1 (en) * 2007-04-27 2008-11-06 Paratek Pharmaceuticals, Inc. Methods for synthesizing and purifying aminoalkyl tetracycline compounds
EA201070233A1 (ru) 2007-07-06 2010-08-30 Паратек Фармасьютикалс, Инк. Способы синтеза замещённых соединений тетрациклина (варианты)
WO2009111064A2 (en) 2008-03-05 2009-09-11 Paratek Pharmaceuticals, Inc. Minocycline compounds and methods of use thereof
PT2271348T (pt) 2008-03-28 2018-04-16 Paratek Pharm Innc Formulação de comprimido oral de composto de tetraciclina
WO2009128913A1 (en) * 2008-04-14 2009-10-22 Paratek Pharmaceuticals, Inc. Substituted tetracycline compounds
TWI585071B (zh) 2008-05-23 2017-06-01 派洛泰克藥物股份有限公司 四環素化合物之甲苯磺酸鹽及同素異形體
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US9561241B1 (en) 2011-06-28 2017-02-07 Medicis Pharmaceutical Corporation Gastroretentive dosage forms for minocycline
ES2611185T3 (es) * 2013-05-20 2017-05-05 Fundación Comunidad Valenciana Centro De Investigación Principe Felipe Conjugados polímero-fármaco para el tratamiento de la amiloidosis
BR112017020358A2 (pt) 2015-03-23 2018-07-17 Biopharmx Inc composição farmacêutica de tetraciclina para uso dermatológico
SG10201913599RA (en) 2016-11-01 2020-02-27 Paratek Pharm Innc 9-aminomethyl minocycline compounds and use thereof in treating community-acquired bacterial pneumonia (cabp)
MA49641A (fr) 2017-07-21 2021-06-02 Almirall Llc Traitement de lésions non inflammatoires
CN113655052B (zh) * 2021-08-03 2023-12-12 哈尔滨工程大学 基于高活性MgO对四环素类抗生素可视化检测的方法

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US1913323A (en) * 1931-02-28 1933-06-06 Hoffmann La Roche Stable concentrated solution for therapeutic purposes
DE647766C (de) * 1931-03-01 1937-07-12 Hoffmanni La Roche & Co Akt Ge Verfahren zur Darstellung haltbarer, konzentrierter, waessriger Loesungen der Cinchonaalkaloide
GB381012A (en) * 1931-12-04 1932-09-29 Andrew Home Morton Process for the manufacture of stable concentrated solutions for therapeutic use
DE662812C (de) * 1931-12-08 1938-07-22 Hoffmanni La Roche & Co Akt Ge Verfahren zur Herstellung haltbarer, waessriger Arzneimittelloesungen
DE673500C (de) * 1933-01-15 1939-03-23 Hoffmann La Roche & Co Akt Ges Verfahren zur Herstellung von haltbaren Loesungen schwer loeslicher Arzneimittel
GB1019164A (en) * 1963-01-30 1966-02-02 Chugai Pharmaceutical Co Ltd Hemostatic preparation for injection and process for the production thereof
DK129969B (da) * 1973-01-11 1974-12-09 Rosco Ak Fremgangsmåde til fremstilling af en klar, stabil, i det væsentlige vandig opløsning af oxytetracyclin.
GB1508601A (en) * 1974-01-19 1978-04-26 Norbrook Labor Ltd Oxytetracycline solution
US4018889A (en) * 1976-01-02 1977-04-19 Pfizer Inc. Oxytetracycline compositions

Also Published As

Publication number Publication date
MX6087E (es) 1984-11-08
PL206050A1 (pl) 1979-03-26
SE7801816L (sv) 1978-10-28
IL54581A0 (en) 1978-07-31
PH12962A (en) 1979-10-19
CS199527B2 (en) 1980-07-31
JPS53136514A (en) 1978-11-29
DK155977C (da) 1989-10-30
PT67895B (en) 1979-11-14
PL110459B1 (en) 1980-07-31
OA05949A (fr) 1981-06-30
SE443507B (sv) 1986-03-03
NZ187046A (en) 1980-03-05
AR217844A1 (es) 1980-04-30
BE866419A (fr) 1978-10-26
DE2817335A1 (de) 1978-11-16
CA1100875A (en) 1981-05-12
ATA300478A (de) 1980-05-15
FI781300A (fi) 1978-10-28
AU503139B1 (en) 1979-08-23
DE2817335B2 (de) 1981-06-11
CH630260A5 (fr) 1982-06-15
DD135445A5 (de) 1979-05-09
GR70062B (no) 1982-07-26
NO781457L (no) 1978-10-30
YU87178A (en) 1984-04-30
FR2388561B1 (no) 1980-07-18
DE2817335C3 (de) 1982-04-22
IT7822720A0 (it) 1978-04-26
RO75099A (ro) 1980-12-30
GB1563478A (en) 1980-03-26
AT360148B (de) 1980-12-29
IE780828L (en) 1978-10-27
IE47049B1 (en) 1983-12-14
ES468749A1 (es) 1979-01-01
BG47943A3 (en) 1990-10-15
FR2388561A1 (fr) 1978-11-24
NL7804455A (nl) 1978-10-31
ZA782400B (en) 1979-04-25
LU79547A1 (fr) 1979-11-07
ZM3878A1 (en) 1978-11-21
EG14348A (en) 1984-09-30
DK182578A (da) 1978-10-28
HU179050B (en) 1982-08-28
PT67895A (en) 1978-05-01
IN148197B (no) 1980-11-29
JPS5632290B2 (no) 1981-07-27
US4126680A (en) 1978-11-21
RO77953A (ro) 1981-12-25
NO148280B (no) 1983-06-06
IT1094557B (it) 1985-08-02
DK155977B (da) 1989-06-12

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