LU79547A1 - Procede de preparation de nouvelles compositions antibiotiques a base d'une tetracycline - Google Patents

Procede de preparation de nouvelles compositions antibiotiques a base d'une tetracycline

Info

Publication number
LU79547A1
LU79547A1 LU79547A LU79547A LU79547A1 LU 79547 A1 LU79547 A1 LU 79547A1 LU 79547 A LU79547 A LU 79547A LU 79547 A LU79547 A LU 79547A LU 79547 A1 LU79547 A1 LU 79547A1
Authority
LU
Luxembourg
Prior art keywords
tetracycline
preparation
compositions based
new antibiotic
antibiotic compositions
Prior art date
Application number
LU79547A
Other languages
English (en)
French (fr)
Inventor
W Armstrong
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of LU79547A1 publication Critical patent/LU79547A1/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/65—Tetracyclines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/22—Heterocyclic compounds, e.g. ascorbic acid, tocopherol or pyrrolidones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Dermatology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Inorganic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Hydrogenated Pyridines (AREA)
LU79547A 1977-04-27 1978-04-27 Procede de preparation de nouvelles compositions antibiotiques a base d'une tetracycline LU79547A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/791,627 US4126680A (en) 1977-04-27 1977-04-27 Tetracycline antibiotic compositions

Publications (1)

Publication Number Publication Date
LU79547A1 true LU79547A1 (fr) 1979-11-07

Family

ID=25154289

Family Applications (1)

Application Number Title Priority Date Filing Date
LU79547A LU79547A1 (fr) 1977-04-27 1978-04-27 Procede de preparation de nouvelles compositions antibiotiques a base d'une tetracycline

Country Status (38)

Country Link
US (1) US4126680A (xx)
JP (1) JPS53136514A (xx)
AR (1) AR217844A1 (xx)
AT (1) AT360148B (xx)
AU (1) AU503139B1 (xx)
BE (1) BE866419A (xx)
BG (1) BG47943A3 (xx)
CA (1) CA1100875A (xx)
CH (1) CH630260A5 (xx)
CS (1) CS199527B2 (xx)
DD (1) DD135445A5 (xx)
DE (1) DE2817335C3 (xx)
DK (1) DK155977C (xx)
EG (1) EG14348A (xx)
ES (1) ES468749A1 (xx)
FI (1) FI781300A (xx)
FR (1) FR2388561A1 (xx)
GB (1) GB1563478A (xx)
GR (1) GR70062B (xx)
HU (1) HU179050B (xx)
IE (1) IE47049B1 (xx)
IL (1) IL54581A0 (xx)
IN (1) IN148197B (xx)
IT (1) IT1094557B (xx)
LU (1) LU79547A1 (xx)
MX (1) MX6087E (xx)
NL (1) NL7804455A (xx)
NO (1) NO148280C (xx)
NZ (1) NZ187046A (xx)
OA (1) OA05949A (xx)
PH (1) PH12962A (xx)
PL (1) PL110459B1 (xx)
PT (1) PT67895B (xx)
RO (2) RO75099A (xx)
SE (1) SE443507B (xx)
YU (1) YU87178A (xx)
ZA (1) ZA782400B (xx)
ZM (1) ZM3878A1 (xx)

Families Citing this family (80)

* Cited by examiner, † Cited by third party
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US4386083A (en) * 1980-04-10 1983-05-31 Walter Hacke Injectable oxytetracycline compositions
US4399127A (en) * 1980-04-10 1983-08-16 Diamond Shamrock Corporation Injectable oxytetracycline compositions
US5589470A (en) * 1990-02-26 1996-12-31 Trustees Of Tufts College Reducing tetracycline resistance in living cells
US4806529A (en) * 1982-11-18 1989-02-21 Trustees Of Tufts College, Tufts University Tetracycline activity enhancement
US5064821A (en) * 1982-11-18 1991-11-12 Trustees Of Tufts College Method and compositions for overcoming tetracycline resistance within living cells
US4769232A (en) * 1984-03-22 1988-09-06 Pfizer Inc. Parenteral formulations of indolmycin
US6756365B2 (en) * 1991-11-06 2004-06-29 Trustees Of Tufts College Reducing tetracycline resistance in living cells
EP0621033A1 (en) * 1993-04-20 1994-10-26 Nostras S.A. Antibiotic composition containing oxytetracycline and glycofurol
US6849615B2 (en) 1999-09-14 2005-02-01 Paratek Pharmaceuticals, Inc. 13-substituted methacycline compounds
CA2672722C (en) 1999-09-14 2013-11-05 Trustees Of Tufts College Methods of preparing substituted tetracyclines with transition metal-based chemistries
US8106225B2 (en) * 1999-09-14 2012-01-31 Trustees Of Tufts College Methods of preparing substituted tetracyclines with transition metal-based chemistries
US6500812B2 (en) 1999-09-14 2002-12-31 Paratek Pharmaceuticals, Inc. 13-substituted methacycline compounds
CA2397863A1 (en) * 2000-01-24 2001-07-26 Trustees Of Tufts College Tetracycline compounds for treatment of cryptosporidium parvum related disorders
MXPA02009482A (es) * 2000-03-31 2004-05-14 Tufts College Compuestos tetraciclinas sustituidos con grupos 7- y 9- carbamato, urea, tiourea, tiocarbamato y heteroaril-amino.
DE60102815D1 (de) * 2000-05-15 2004-05-19 Paratek Pharm Innc 7-substituierte kondensierte ring-tetrazyclin- verbindungen
US20020132798A1 (en) 2000-06-16 2002-09-19 Nelson Mark L. 7-phenyl-substituted tetracycline compounds
US20020128238A1 (en) 2000-06-16 2002-09-12 Nelson Mark L. 7-phenyl-substituted tetracycline compounds
US20040224927A1 (en) * 2000-06-16 2004-11-11 Trustees Of Tufts College 7-N-substituted phenyl tetracycline compounds
US7094806B2 (en) 2000-07-07 2006-08-22 Trustees Of Tufts College 7, 8 and 9-substituted tetracycline compounds
CZ303702B6 (cs) 2000-07-07 2013-03-20 Trustees Of Tufts College Minocyklinové slouceniny
IL153672A0 (en) 2000-07-07 2003-07-06 Tufts College 7-substituted tetracycline compounds
MXPA03000036A (es) 2000-07-07 2003-07-14 Tufts College Compuestos de metaciclina sustituidos en posicion 13.
EP1303479B1 (en) 2000-07-07 2011-04-06 Trustees Of Tufts College 7-, 8- and 9-substituted tetracycline compounds
US20050143353A1 (en) * 2000-07-07 2005-06-30 Paratek Pharmaceuticals, Inc. 13-Substituted methacycline compounds
EP2298732A1 (en) 2001-03-13 2011-03-23 Paratek Pharmaceuticals, Inc. 7,9-Substituted tetracycline compounds
US7553828B2 (en) * 2001-03-13 2009-06-30 Paratek Pharmaceuticals, Inc. 9-aminomethyl substituted minocycline compounds
WO2002072506A2 (en) * 2001-03-13 2002-09-19 Paratek Pharmaceuticals, Inc. 7-pyrollyl tetracycline compounds and methods of use thereof
US6841546B2 (en) 2001-03-14 2005-01-11 Paratek Pharmaceuticals, Inc. Substituted tetracycline compounds as antifungal agents
CA2440757A1 (en) 2001-03-14 2002-09-19 Michael Draper Substituted tetracycline compounds as synergistic antifungal agents
US8088820B2 (en) * 2001-04-24 2012-01-03 Paratek Pharmaceuticals, Inc. Substituted tetracycline compounds for the treatment of malaria
ES2338994T3 (es) 2001-04-24 2010-05-14 Paratek Pharmaceuticals, Inc. Compuestos de tetraciclina sustituida para el tratamiento de la malaria.
EP2322501B1 (en) 2002-01-08 2015-08-05 Paratek Pharmaceuticals, Inc. 4-dedimethylamino tetracycline compounds
CA2478335C (en) 2002-03-08 2011-05-10 Paratek Pharmaceuticals, Inc. Amino-methyl substituted tetracycline compounds
JP2005520846A (ja) 2002-03-21 2005-07-14 パラテック ファーマシューティカルズ インコーポレイテッド 置換されたテトラサイクリン化合物。
KR101148415B1 (ko) 2002-07-12 2012-05-21 파라테크 파마슈티컬스, 인크. 3, 10, 및 12ａ 치환된 테트라시클린 화합물
CA2502464A1 (en) 2002-10-24 2004-05-06 Paratek Pharmaceuticals, Inc. Substituted tetracycline compounds for the treatment of malaria
AU2004259659B2 (en) 2003-07-09 2011-11-03 Paratek Pharmaceuticals, Inc. Substituted tetracycline compounds
JP4738333B2 (ja) 2003-07-09 2011-08-03 パラテック ファーマシューティカルズ インコーポレイテッド ９−アミノメチルテトラサイクリン化合物のプロドラッグ
CN1893956A (zh) * 2003-07-25 2007-01-10 沃纳奇尔科特公司 多西环素金属络合物固体剂型
EP2332904A3 (en) 2004-01-15 2012-04-11 Paratek Pharmaceuticals, Inc. Derivatives of tetracycline compounds
TWI261038B (en) * 2004-08-11 2006-09-01 Bo-Cheng Chen Bicycle gear-shifting handgrip
EP1805134B1 (en) 2004-10-25 2012-06-20 Paratek Pharmaceuticals, Inc. 4-aminotetracyclines and methods of use thereof
WO2006047756A2 (en) 2004-10-25 2006-05-04 Paratek Pharmaceuticals, Inc. Substituted tetracycline compounds
AU2006210406C1 (en) 2005-02-04 2013-03-07 Paratek Pharmaceuticals, Inc. 11a, 12-derivatives of tetracycline compounds
US8252776B2 (en) 2007-04-02 2012-08-28 Medicis Pharmaceutical Corporation Minocycline oral dosage forms for the treatment of acne
US7919483B2 (en) * 2005-06-24 2011-04-05 Medicis Pharmaceutical Corporation Method for the treatment of acne
US8722650B1 (en) 2005-06-24 2014-05-13 Medicis Pharmaceutical Corporation Extended-release minocycline dosage forms
US20080241235A1 (en) * 2007-04-02 2008-10-02 Medicis Pharmaceutical Corporation Minocycline oral dosage forms for the treatment of acne
US7544373B2 (en) * 2007-04-02 2009-06-09 Medicis Pharmaceutical Corporation Minocycline oral dosage forms for the treatment of acne
US20080242642A1 (en) * 2007-04-02 2008-10-02 Medicis Pharmaceutical Corporation Minocycline oral dosage forms for the treatment of acne
US7541347B2 (en) * 2007-04-02 2009-06-02 Medicis Pharmaceutical Coropration Minocycline oral dosage forms for the treatment of acne
EP2298324A1 (en) 2006-01-24 2011-03-23 Paratek Pharmaceuticals, Inc. Methods of increasing oral bioavailability of tetracyclines
US20070244335A1 (en) * 2006-04-17 2007-10-18 Teva Pharmaceutical Industries Ltd. Isolation of tetracycline derivatives
PT2016045E (pt) * 2006-04-24 2015-02-05 Teva Pharma Forma cristalina de tigeciclina e processos para a sua preparação
US8198470B2 (en) * 2006-04-24 2012-06-12 Teva Pharmaceutical Industries Ltd. Crystalline form II of tigecycline and processes for preparation thereof
AU2007249696A1 (en) * 2006-05-15 2007-11-22 Paratek Pharmaceuticals, Inc. Methods of regulating expression of genes or of gene products using substituted tetracycline compounds
ES2315123B1 (es) * 2006-09-25 2009-12-30 Divasa-Farmavic, S.A. Composiciones farmaceuticas estables de tetraciclinas en solucion, procedimiento para su obtencion y sus usos.
WO2008045507A2 (en) 2006-10-11 2008-04-17 Paratek Pharmaceuticals, Inc. Substituted tetracycline compounds for treatment of bacillus anthracis infections
KR101538175B1 (ko) 2006-12-21 2015-07-20 파라테크 파마슈티컬스, 인크. 박테리아, 바이러스 및 기생충 감염의 치료를 위한 테트라시클린 유도체
AU2007338681B2 (en) 2006-12-21 2013-09-26 Paratek Pharmaceuticals, Inc. Substituted tetracycline compounds for treatment of inflammatory skin disorders
AU2012230089B2 (en) * 2007-03-23 2013-11-21 Molecular Research Center, Inc. Anti-inflammatory compositions comprising tetracyclines and use thereof in therapy
KR20090122994A (ko) * 2007-03-23 2009-12-01 몰레큘러 리서치 센터, 인크. 테트라사이클린류를 함유하는 항염증성 조성물 및 이의 치료 용도
US20080241197A1 (en) * 2007-04-02 2008-10-02 Medicis Pharmaceutical Corporation Minocycline dosage forms for the treatment of acne
AU2008239606A1 (en) 2007-04-12 2008-10-23 Paratek Pharmaceuticals, Inc. Methods for treating spinal muscular atrophy using tetracycline compounds
AU2008246119A1 (en) * 2007-04-27 2008-11-06 Paratek Pharmaceuticals, Inc. Methods for synthesizing and purifying aminoalkyl tetracycline compounds
EA201070233A1 (ru) 2007-07-06 2010-08-30 Паратек Фармасьютикалс, Инк. Способы синтеза замещённых соединений тетрациклина (варианты)
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PT2271348T (pt) 2008-03-28 2018-04-16 Paratek Pharm Innc Formulação de comprimido oral de composto de tetraciclina
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ES2611185T3 (es) * 2013-05-20 2017-05-05 Fundación Comunidad Valenciana Centro De Investigación Principe Felipe Conjugados polímero-fármaco para el tratamiento de la amiloidosis
MX2017012062A (es) 2015-03-23 2018-06-18 Biopharmx Inc Composicion farmaceutica de tetraciclina para uso dermatologico.
BR112019008897A2 (pt) 2016-11-01 2019-08-13 Paratek Pharm Innc método para tratar pneumonia bacteriana adquirida na comunidade.
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US1913323A (en) * 1931-02-28 1933-06-06 Hoffmann La Roche Stable concentrated solution for therapeutic purposes
DE647766C (de) * 1931-03-01 1937-07-12 Hoffmanni La Roche & Co Akt Ge Verfahren zur Darstellung haltbarer, konzentrierter, waessriger Loesungen der Cinchonaalkaloide
GB381012A (en) * 1931-12-04 1932-09-29 Andrew Home Morton Process for the manufacture of stable concentrated solutions for therapeutic use
DE662812C (de) * 1931-12-08 1938-07-22 Hoffmanni La Roche & Co Akt Ge Verfahren zur Herstellung haltbarer, waessriger Arzneimittelloesungen
DE673500C (de) * 1933-01-15 1939-03-23 Hoffmann La Roche & Co Akt Ges Verfahren zur Herstellung von haltbaren Loesungen schwer loeslicher Arzneimittel
GB1019164A (en) * 1963-01-30 1966-02-02 Chugai Pharmaceutical Co Ltd Hemostatic preparation for injection and process for the production thereof
DK129969B (da) * 1973-01-11 1974-12-09 Rosco Ak Fremgangsmåde til fremstilling af en klar, stabil, i det væsentlige vandig opløsning af oxytetracyclin.
GB1508601A (en) * 1974-01-19 1978-04-26 Norbrook Labor Ltd Oxytetracycline solution
US4018889A (en) * 1976-01-02 1977-04-19 Pfizer Inc. Oxytetracycline compositions

Also Published As

Publication number Publication date
EG14348A (en) 1984-09-30
MX6087E (es) 1984-11-08
RO77953A (ro) 1981-12-25
CS199527B2 (en) 1980-07-31
IT1094557B (it) 1985-08-02
PT67895B (en) 1979-11-14
PT67895A (en) 1978-05-01
SE443507B (sv) 1986-03-03
DD135445A5 (de) 1979-05-09
GB1563478A (en) 1980-03-26
CH630260A5 (fr) 1982-06-15
PL110459B1 (en) 1980-07-31
ZM3878A1 (en) 1978-11-21
ZA782400B (en) 1979-04-25
FR2388561B1 (xx) 1980-07-18
DK182578A (da) 1978-10-28
AU503139B1 (en) 1979-08-23
IL54581A0 (en) 1978-07-31
OA05949A (fr) 1981-06-30
YU87178A (en) 1984-04-30
AR217844A1 (es) 1980-04-30
US4126680A (en) 1978-11-21
IE780828L (en) 1978-10-27
IE47049B1 (en) 1983-12-14
CA1100875A (en) 1981-05-12
NO148280C (no) 1983-09-21
BE866419A (fr) 1978-10-26
FR2388561A1 (fr) 1978-11-24
GR70062B (xx) 1982-07-26
DE2817335B2 (de) 1981-06-11
JPS53136514A (en) 1978-11-29
DE2817335C3 (de) 1982-04-22
BG47943A3 (en) 1990-10-15
PL206050A1 (pl) 1979-03-26
SE7801816L (sv) 1978-10-28
NZ187046A (en) 1980-03-05
AT360148B (de) 1980-12-29
HU179050B (en) 1982-08-28
NL7804455A (nl) 1978-10-31
JPS5632290B2 (xx) 1981-07-27
DK155977C (da) 1989-10-30
PH12962A (en) 1979-10-19
IN148197B (xx) 1980-11-29
ATA300478A (de) 1980-05-15
NO781457L (no) 1978-10-30
NO148280B (no) 1983-06-06
IT7822720A0 (it) 1978-04-26
DE2817335A1 (de) 1978-11-16
DK155977B (da) 1989-06-12
FI781300A (fi) 1978-10-28
ES468749A1 (es) 1979-01-01
RO75099A (ro) 1980-12-30

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