NL300208I2 - Kristallijne vrije zuurvorm van ceftiofur. - Google Patents

Kristallijne vrije zuurvorm van ceftiofur.

Info

Publication number
NL300208I2
NL300208I2 NL300208C NL300208C NL300208I2 NL 300208 I2 NL300208 I2 NL 300208I2 NL 300208 C NL300208 C NL 300208C NL 300208 C NL300208 C NL 300208C NL 300208 I2 NL300208 I2 NL 300208I2
Authority
NL
Netherlands
Prior art keywords
ceftiofur
pct
free acid
acid form
crystalline free
Prior art date
Application number
NL300208C
Other languages
English (en)
Dutch (nl)
Other versions
NL300208I1 (nl
Original Assignee
Upjohn Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Upjohn Co filed Critical Upjohn Co
Publication of NL300208I1 publication Critical patent/NL300208I1/nl
Publication of NL300208I2 publication Critical patent/NL300208I2/nl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A61K31/542—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/545—Compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins, cefaclor, or cephalexine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Epidemiology (AREA)
  • Virology (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
NL300208C 1993-03-12 2005-11-21 Kristallijne vrije zuurvorm van ceftiofur. NL300208I2 (nl)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US3329193A 1993-03-12 1993-03-12
PCT/US1994/001862 WO1994020505A1 (en) 1993-03-12 1994-03-07 Crystalline ceftiofur free acid

Publications (2)

Publication Number Publication Date
NL300208I1 NL300208I1 (nl) 2006-02-01
NL300208I2 true NL300208I2 (nl) 2006-05-01

Family

ID=21869579

Family Applications (1)

Application Number Title Priority Date Filing Date
NL300208C NL300208I2 (nl) 1993-03-12 2005-11-21 Kristallijne vrije zuurvorm van ceftiofur.

Country Status (31)

Country Link
US (1) US5721359A (enExample)
EP (1) EP0690864B1 (enExample)
JP (1) JP3852946B2 (enExample)
KR (1) KR100296810B1 (enExample)
CN (1) CN1055090C (enExample)
AT (1) ATE202109T1 (enExample)
AU (1) AU694419B2 (enExample)
BR (1) BR1101034A (enExample)
CA (1) CA2155322C (enExample)
CZ (1) CZ289332B6 (enExample)
DE (2) DE69427469T2 (enExample)
DK (1) DK0690864T3 (enExample)
ES (1) ES2157254T3 (enExample)
FI (1) FI120307B (enExample)
FR (1) FR05C0045I2 (enExample)
GR (1) GR3036514T3 (enExample)
HU (1) HU222244B1 (enExample)
IL (1) IL108910A (enExample)
LU (1) LU91206I2 (enExample)
LV (1) LV12889B (enExample)
NL (1) NL300208I2 (enExample)
NO (2) NO313199B1 (enExample)
NZ (1) NZ263002A (enExample)
PL (1) PL184611B1 (enExample)
PT (1) PT690864E (enExample)
RU (1) RU2136685C1 (enExample)
SI (1) SI0690864T1 (enExample)
SK (1) SK283674B6 (enExample)
TW (1) TW267170B (enExample)
WO (1) WO1994020505A1 (enExample)
ZA (1) ZA941586B (enExample)

Families Citing this family (73)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5736151A (en) * 1996-12-09 1998-04-07 Pharmacia & Upjohn Company Antibiotic oil suspensions
US6074657A (en) * 1997-03-20 2000-06-13 Pharmacia & Upjohn Company Administration of an injectable antibiotic in the ear of an animal
EP1317256B1 (en) * 2000-09-12 2008-10-29 Pharmacia & Upjohn Company LLC Pharmaceutical composition having modified carrier
US7829100B2 (en) * 2000-09-12 2010-11-09 Teagarden Dirk L Pharmaceutical composition having modified carrier
KR100423895B1 (ko) * 2001-02-19 2004-03-24 주식회사 엘지생명과학 셉티오퍼 하이드로클로라이드의 현탁제 조성물
US20030109525A1 (en) * 2001-07-10 2003-06-12 Pharmacia & Upjohn Company Crystalline thiazine oxazolidinones
CN100364991C (zh) 2001-08-15 2008-01-30 法玛西雅厄普约翰美国公司 2,4-二甲基-1h-吡咯-3-甲酰胺衍生物的苹果酸盐的晶体、其制备方法和其组合物
AU2003230697B2 (en) 2002-03-21 2008-07-17 Zoetis Services Llc Method of administering an injectable antibiotic to the ear of an animal
US20040022815A1 (en) * 2002-08-05 2004-02-05 Orchid Health Care Novel pharmaceutical composition of ceftiofur
KR20040015622A (ko) * 2002-08-13 2004-02-19 대한뉴팜(주) 세프티오푸르나트륨을 활성성분으로 함유하는 현탁주사액조성물
US20040115822A1 (en) * 2002-09-12 2004-06-17 Schapaugh Randal Lee Methods of measuring the dissolution rate of an analyte in a non-aqueous liquid composition
US7659061B2 (en) * 2002-11-19 2010-02-09 Pharmacia & Upjohn Company Pharmaceutical compositions having a modified vehicle
US20040115837A1 (en) * 2002-11-27 2004-06-17 Schapaugh Randal Lee Methods of measuring the dissolution rate of an analyte in a non-aqueous liquid composition
US7842791B2 (en) * 2002-12-19 2010-11-30 Nancy Jean Britten Dispersible pharmaceutical compositions
PL1606293T3 (pl) * 2003-03-27 2010-01-29 Basilea Pharmaceutica Ag Cefalosporyna w postaci krystalicznej
CZ23090U1 (cs) * 2004-03-25 2011-12-19 Astellas Pharma Inc. Kompozice pevného farmaceutického prípravku solifenacinu nebo jeho soli
US7815939B2 (en) 2005-07-20 2010-10-19 Astellas Pharma Inc. Coated fine particles containing drug for intrabuccally fast disintegrating dosage forms
US8470809B2 (en) * 2005-10-12 2013-06-25 Orchid Chemicals & Pharmaceuticals Limited Crystalline sodium salt of cephalosporin antibiotic
JP2009511563A (ja) * 2005-10-12 2009-03-19 オーキッド ケミカルズ アンド ファーマシューティカルズ リミテッド セファロスポリン抗生物質の結晶性ナトリウム塩
PL2195293T3 (pl) 2007-08-22 2014-03-31 Astrazeneca Ab Pochodne cyklopropyloamidu
WO2010036427A1 (en) 2008-06-17 2010-04-01 Brigham Young University Cationic steroid antimicrobial diagnostic, detection, screening and imaging methods
WO2010020871A2 (en) * 2008-08-22 2010-02-25 Orchid Chemicals & Pharmaceuticals Limited Crystalline sodium salt of cephalosporin antibiotic
US20100125060A1 (en) * 2008-11-19 2010-05-20 Majid Razzak Formulations comprising ceftiofur and ketoprofen or ceftiofur and benzyl alcohol
EA018907B1 (ru) * 2009-01-30 2013-11-29 ГЛЭКСОСМИТКЛАЙН ЭлЭлСи Кристаллический гидрохлорид n-{(1s)-2-амино-1-[(3-фторфенил)метил]этил}-5-хлор-4-(4-хлор-1-метил-1h-пиразол-5-ил)-2-тиофенкарбоксамида
TW201039825A (en) 2009-02-20 2010-11-16 Astrazeneca Ab Cyclopropyl amide derivatives 983
EP2536701A4 (en) * 2010-02-18 2014-05-07 Astrazeneca Ab SOLID FORMS WITH A CYCLOPROPYLAMID DERIVATIVE
WO2011102795A1 (en) * 2010-02-18 2011-08-25 Astrazeneca Ab New crystalline form of a cyclopropyl benzamide derivative
JP2014513116A (ja) * 2011-05-02 2014-05-29 ゾエティス・エルエルシー 抗菌剤として有用な新規セファロスポリン
US10676501B2 (en) 2011-07-20 2020-06-09 Brigham Young University Hydrogel materials incorporating eluting ceragenin compound
US9694019B2 (en) 2011-09-13 2017-07-04 Brigham Young University Compositions and methods for treating bone diseases and broken bones
CN104080459B (zh) 2011-09-13 2018-07-03 布莱阿姆青年大学 用于治疗骨疾病和断骨的组合物
WO2013040269A1 (en) 2011-09-13 2013-03-21 Brigham Young University Products for healing of tissue wounds
US9603859B2 (en) 2011-09-13 2017-03-28 Brigham Young University Methods and products for increasing the rate of healing of tissue wounds
NZ626144A (en) 2011-12-21 2016-05-27 Univ Brigham Young Oral care compositions
CN102584855B (zh) * 2012-02-16 2014-06-25 青岛科技大学 一种改进的头孢噻呋的制备方法
US9533063B1 (en) 2012-03-01 2017-01-03 Brigham Young University Aerosols incorporating ceragenin compounds and methods of use thereof
CA2872399C (en) 2012-05-02 2021-01-12 Brigham Young University Ceragenin particulate materials and methods for making same
CA2888259C (en) 2012-10-17 2019-05-28 Brigham Young University Treatment and prevention of mastitis
US9518004B2 (en) * 2012-12-03 2016-12-13 Kaneka Corporation Reduced coenzyme Q10 derivative and method for production thereof
JP6294352B2 (ja) 2013-01-07 2018-03-14 ブリガム・ヤング・ユニバーシティＢｒｉｇｈａｍ Ｙｏｕｎｇ Ｕｎｉｖｅｒｓｉｔｙ 細胞増殖を減少させ、ある特定の疾患を治療する方法
US11524015B2 (en) 2013-03-15 2022-12-13 Brigham Young University Methods for treating inflammation, autoimmune disorders and pain
CN110420211A (zh) 2013-03-15 2019-11-08 布莱阿姆青年大学 治疗炎症、自身免疫性疾病和疼痛的方法
US10568893B2 (en) 2013-03-15 2020-02-25 Brigham Young University Methods for treating inflammation, autoimmune disorders and pain
RU2546675C2 (ru) * 2013-04-11 2015-04-10 Федеральное казённое предприятие "Государственный научно-исследовательский институт химических продуктов" (ФКП "ГосНИИХП") Способ определения степени кристалличности составов на основе дифениламина
US9387215B2 (en) 2013-04-22 2016-07-12 Brigham Young University Animal feed including cationic cholesterol additive and related methods
KR20160051833A (ko) * 2013-09-05 2016-05-11 미쓰비시 타나베 파마 코퍼레이션 신규한 결정성 아릴알킬아민 화합물 및 그의 제조 방법
US11690855B2 (en) 2013-10-17 2023-07-04 Brigham Young University Methods for treating lung infections and inflammation
US20150203527A1 (en) 2014-01-23 2015-07-23 Brigham Young University Cationic steroidal antimicrobials
CA2844321C (en) 2014-02-27 2021-03-16 Brigham Young University Cationic steroidal antimicrobial compounds
US9867836B2 (en) 2014-03-13 2018-01-16 Brigham Young University Lavage and/or infusion using CSA compounds for increasing fertility in a mammal
US10220045B2 (en) 2014-03-13 2019-03-05 Brigham Young University Compositions and methods for forming stabilized compositions with reduced CSA agglomeration
US9931350B2 (en) 2014-03-14 2018-04-03 Brigham Young University Anti-infective and osteogenic compositions and methods of use
US9686966B2 (en) 2014-04-30 2017-06-27 Brigham Young University Methods and apparatus for cleaning or disinfecting a water delivery system
US10441595B2 (en) 2014-06-26 2019-10-15 Brigham Young University Methods for treating fungal infections
US10238665B2 (en) 2014-06-26 2019-03-26 Brigham Young University Methods for treating fungal infections
US10227376B2 (en) 2014-08-22 2019-03-12 Brigham Young University Radiolabeled cationic steroid antimicrobials and diagnostic methods
US10155788B2 (en) 2014-10-07 2018-12-18 Brigham Young University Cationic steroidal antimicrobial prodrug compositions and uses thereof
EA035145B1 (ru) 2014-10-21 2020-05-06 Ариад Фармасьютикалз, Инк. Кристаллические формы 5-хлор-n4-[2-(диметилфосфорил)фенил]-n2-{2-метокси-4-[4-(4-метилпиперазин-1-ил)пиперидин-1-ил]фенил}пиримидин-2,4-диамина
WO2016172543A1 (en) 2015-04-22 2016-10-27 Savage Paul B Methods for the synthesis of ceragenins
WO2016172553A1 (en) 2015-04-22 2016-10-27 Savage Paul B Methods for the synthesis of ceragenins
KR101753842B1 (ko) * 2015-05-12 2017-07-04 한국화학연구원 불화퀴놀론계 항생제를 담지한 서방형 제제 및 이의 제조방법
US9434759B1 (en) 2015-05-18 2016-09-06 Brigham Young University Cationic steroidal antimicrobial compounds and methods of manufacturing such compounds
CN106543203B (zh) * 2015-09-18 2019-07-02 瑞普（天津）生物药业有限公司 一种长效头孢噻呋自由酸晶体的制备方法
JP7046815B2 (ja) * 2016-01-22 2022-04-04 サンド・アクチエンゲゼルシヤフト 結晶質エラバサイクリンビス塩酸塩
US10226550B2 (en) 2016-03-11 2019-03-12 Brigham Young University Cationic steroidal antimicrobial compositions for the treatment of dermal tissue
KR101898282B1 (ko) * 2016-05-24 2018-09-13 주식회사 고려비엔피 항생제의 서방형 수의학적 조성물 및 이의 제조방법
JP2019524710A (ja) 2016-07-07 2019-09-05 アイアンウッド ファーマシューティカルズ インコーポレイテッド Ｓｇｃ刺激剤の固体形態
US10959433B2 (en) 2017-03-21 2021-03-30 Brigham Young University Use of cationic steroidal antimicrobials for sporicidal activity
US11186556B1 (en) * 2018-10-16 2021-11-30 Celgene Corporation Salts of a thiazolidinone compound, solid forms, compositions and methods of use thereof
UA119735C2 (uk) 2018-12-20 2019-07-25 Анатолій Семенович Редер Фармацевтична сполука, спосіб її отримання та застосування як лікарського засобу
US12186328B2 (en) 2019-05-23 2025-01-07 Brigham Young University Use of CSA compounds to stimulate stem cells and hair growth
TW202233625A (zh) * 2020-11-18 2022-09-01 美商傳達治療有限公司 Ｆｇｆｒ抑制劑及其製造及使用方法
CN117229296A (zh) * 2023-09-14 2023-12-15 广东温氏大华农生物科技有限公司 一种头孢噻呋酸晶体及其制备方法与应用

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1207933B (de) * 1962-12-26 1965-12-30 American Home Prod Verfahren zur Herstellung von kristallwasser-freiem D-alpha-Aminobenzylpenicillin
CY773A (en) * 1967-09-05 1975-03-01 Bristol Myers Co Antibacterial agents and a process for the preparation thereof
DK154939C (da) * 1974-12-19 1989-06-12 Takeda Chemical Industries Ltd Analogifremgangsmaade til fremstilling af thiazolylacetamido-cephemforbindelser eller farmaceutisk acceptable salte eller estere deraf
DE2760123C2 (de) * 1976-01-23 1986-04-30 Roussel-Uclaf, Paris 7-Aminothiazolyl-syn-oxyiminoacetamidocephalosporansäuren, ihre Herstellung und sie enthaltende pharmazeutische Zusammensetzungen
GB1532682A (en) * 1976-04-27 1978-11-22 Bristol Myers Co Process for the preparation of cephadroxil
FR2479229B1 (fr) * 1980-03-26 1986-01-17 Clin Midy Nouveaux derives des cephalosporines, leur procede de preparation et les medicaments utilisables comme antibiotiques qui contiennent lesdits derives
IL63968A (en) * 1980-10-01 1985-10-31 Glaxo Group Ltd Form 2 ranitidine hydrochloride,its preparation and pharmaceutical compositions containing it
US4400503A (en) * 1981-10-30 1983-08-23 Eli Lilly And Company Purification of syn-7-[[(2-amino-4-thiazolyl)(methoxyimino) acetyl]amino]-3-methyl-3-cephem-4-carboxylic acid
DE3313818A1 (de) * 1983-04-16 1984-10-18 Hoechst Ag, 6230 Frankfurt Neue kristallmodifikation von ceftazidim
HU196714B (en) * 1984-10-04 1989-01-30 Monsanto Co Process for producing non-aqueous composition comprising somatotropin
US4902683A (en) * 1984-10-25 1990-02-20 The Upjohn Company Crystalline cephalosporin hydrohalide salts
IT1181672B (it) * 1984-10-25 1987-09-30 Upjohn Co Cefalosporina alogenidrato cristallino
FR2585705B1 (fr) * 1985-08-05 1989-01-13 Bristol Myers Co Sels de cephalosporine et compositions injectables
EP0233255B1 (en) * 1985-08-12 1996-05-29 The Upjohn Company Conversion of cephalosporin hydrohalide salt to alkali metal salt
GB8608962D0 (en) * 1986-04-12 1986-05-14 Beecham Group Plc Beta-lactam antibiotics
IT1214587B (it) * 1986-12-23 1990-01-18 Giovanni Bonfanti Metodo per la produzione diprodotti cristallini puri.
EP0278656B1 (en) * 1987-02-02 1992-06-03 Eli Lilly And Company Process for preparing ceftazidime pentahydrate
AU611461B2 (en) * 1987-07-29 1991-06-13 Pharmacia & Upjohn Company Controlled release of antibiotic salts from an implant
WO1989004313A1 (en) * 1987-11-10 1989-05-18 The Upjohn Company Cephalosporin antibiotics
US4877782A (en) * 1988-02-16 1989-10-31 The Upjohn Company Zinc ceftiofur complexes

Also Published As

Publication number Publication date
DK0690864T3 (da) 2001-09-17
DE69427469D1 (en) 2001-07-19
HUT73781A (en) 1996-09-30
NO953564D0 (no) 1995-09-11
RU2136685C1 (ru) 1999-09-10
NZ263002A (en) 1996-12-20
IL108910A0 (en) 1994-06-24
AU694419B2 (en) 1998-07-23
FR05C0045I1 (enExample) 2006-01-06
PT690864E (pt) 2001-11-30
NL300208I1 (nl) 2006-02-01
BR1101034A (pt) 2002-04-30
NO953564L (no) 1995-11-07
SK111495A3 (en) 1995-12-06
EP0690864B1 (en) 2001-06-13
AU6351094A (en) 1994-09-26
KR100296810B1 (ko) 2001-10-24
JPH08507519A (ja) 1996-08-13
ATE202109T1 (de) 2001-06-15
ES2157254T3 (es) 2001-08-16
CN1119016A (zh) 1996-03-20
DE69427469T2 (de) 2001-10-31
JP3852946B2 (ja) 2006-12-06
SK283674B6 (sk) 2003-11-04
CN1055090C (zh) 2000-08-02
FI954250A0 (fi) 1995-09-11
US5721359A (en) 1998-02-24
NO2005025I1 (no) 2005-12-05
ZA941586B (en) 1995-09-07
SI0690864T1 (en) 2001-10-31
TW267170B (enExample) 1996-01-01
CZ9502290A3 (cs) 2001-08-15
CA2155322C (en) 2000-02-29
DE122005000055I2 (de) 2008-06-05
LU91206I2 (fr) 2006-05-30
NO313199B1 (no) 2002-08-26
NO2005025I2 (no) 2010-11-22
FR05C0045I2 (enExample) 2007-08-03
FI120307B (fi) 2009-09-15
IL108910A (en) 1999-10-28
LV12889B (lv) 2002-12-20
EP0690864A1 (en) 1996-01-10
CA2155322A1 (en) 1994-09-15
DE122005000055I1 (de) 2006-02-23
PL310556A1 (en) 1995-12-27
HU222244B1 (hu) 2003-05-28
WO1994020505A1 (en) 1994-09-15
PL184611B1 (pl) 2002-11-29
GR3036514T3 (en) 2001-12-31
FI954250L (fi) 1995-09-11
HU9501960D0 (en) 1995-09-28
CZ289332B6 (cs) 2002-01-16

Similar Documents

Publication Publication Date Title
NL300208I1 (nl) Kristallijne vrije zuurvorm van ceftiofur.
PL312739A1 (en) New derivatives of perhydro isoindole, their production and pharmaceutical compounds containing them
HUT72970A (en) Risperidone pamoate, pharmaceutical composition containing it and process for their production
IL108520A0 (en) Imidazopyridine derivatives, processes for the preparation thereof, and pharmaceutical compositions containing them
AU1240395A (en) N-substituted azabicycloalkane derivatives as neuroleptika asf
HUT71584A (en) Lipopeptide derivatives and pharmaceutical compositions containing them
HUT72594A (en) New prednisolone derivative, process for its production, pharmaceutical composition containing the same
AU2797695A (en) Thiazolidine derivatives, their preparation and drugs containing same
IL104816A0 (en) Indoles
TW252979B (enExample)
AU6303996A (en) Mono- and disulfo-substituted anthraquinones and their use for the treatment of bone matrix disorders
TW261614B (enExample)
HRP950437A2 (en) N-substituted azabicycloheptane derivatives, their production and use
IL107520A0 (en) Substituted ortho-ethenylphenylacetic acid derivatives and pharmaceutical compositions containing them
AU7228094A (en) Substituted arylthioalkylthiopyridines
AU1067295A (en) Substituted aminoalkylaminopyridines
KR960700223A (ko) C-치환 디에틸렌 트리아민의 제조 방법(Process for the Production of C-Substituted Diethylenetriamines)
HUT42492A (en) Process for producing cepheme-carboxylic acid derivatives and pharmaceutical compositions containing them as active agents
IL99369A0 (en) Pharmaceutical compositions containing substituted 2-cyclohexene derivatives
GR3002538T3 (en) Crystal modification of 3-methoxy-4-(4'-amino benzolsulfonamido)-1,2,5-thiadiazole, process for its production and pharmaceutical compositions containing it