NL300053I2 - Indoolderivaten voor een behandeling van migraine. - Google Patents

Indoolderivaten voor een behandeling van migraine.

Info

Publication number
NL300053I2
NL300053I2 NL300053C NL300053C NL300053I2 NL 300053 I2 NL300053 I2 NL 300053I2 NL 300053 C NL300053 C NL 300053C NL 300053 C NL300053 C NL 300053C NL 300053 I2 NL300053 I2 NL 300053I2
Authority
NL
Netherlands
Prior art keywords
image
alkyl group
indole derivatives
migraine treatment
migraine
Prior art date
Application number
NL300053C
Other languages
English (en)
Dutch (nl)
Other versions
NL300053I1 (nl
Original Assignee
Almirall Prodesfarma Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=10719423&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=NL300053(I2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Almirall Prodesfarma Sa filed Critical Almirall Prodesfarma Sa
Publication of NL300053I1 publication Critical patent/NL300053I1/nl
Publication of NL300053I2 publication Critical patent/NL300053I2/nl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/14—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
    • C07D209/16—Tryptamines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/06—Antimigraine agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biomedical Technology (AREA)
  • Public Health (AREA)
  • Pain & Pain Management (AREA)
  • Psychiatry (AREA)
  • Anesthesiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Processing Of Solid Wastes (AREA)
  • Fertilizers (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pyrane Compounds (AREA)
  • Steroid Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
NL300053C 1992-07-28 2001-08-21 Indoolderivaten voor een behandeling van migraine. NL300053I2 (nl)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB929216009A GB9216009D0 (en) 1992-07-28 1992-07-28 New indol derivatives
PCT/EP1993/001901 WO1994002460A1 (en) 1992-07-28 1993-07-19 Indol derivatives for the treatment of migraine

Publications (2)

Publication Number Publication Date
NL300053I1 NL300053I1 (nl) 2001-11-01
NL300053I2 true NL300053I2 (nl) 2002-04-02

Family

ID=10719423

Family Applications (1)

Application Number Title Priority Date Filing Date
NL300053C NL300053I2 (nl) 1992-07-28 2001-08-21 Indoolderivaten voor een behandeling van migraine.

Country Status (32)

Country Link
US (1) US5565447A (enExample)
EP (1) EP0605697B1 (enExample)
JP (1) JP2716585B2 (enExample)
KR (1) KR100191830B1 (enExample)
CN (1) CN1035179C (enExample)
AT (1) ATE177080T1 (enExample)
BR (2) BR9305589A (enExample)
CA (1) CA2120028C (enExample)
CZ (1) CZ282659B6 (enExample)
DE (2) DE10199016I2 (enExample)
DK (1) DK0605697T3 (enExample)
EC (1) ECSP930953A (enExample)
EG (1) EG20340A (enExample)
FI (1) FI109998B (enExample)
GB (1) GB9216009D0 (enExample)
GR (1) GR3029915T3 (enExample)
HU (2) HUT70518A (enExample)
IL (1) IL106387A (enExample)
LU (1) LU90758I2 (enExample)
MX (1) MX9304524A (enExample)
MY (1) MY113266A (enExample)
NL (1) NL300053I2 (enExample)
NO (1) NO180231C (enExample)
NZ (1) NZ254152A (enExample)
PL (1) PL174352B1 (enExample)
RU (1) RU2117667C1 (enExample)
SG (1) SG48708A1 (enExample)
TW (1) TW235297B (enExample)
UA (1) UA27818C2 (enExample)
UY (1) UY23624A1 (enExample)
WO (1) WO1994002460A1 (enExample)
ZA (1) ZA935316B (enExample)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2712591B1 (fr) * 1993-11-19 1996-02-09 Pf Medicament Nouvelles arylpipérazines dérivées d'indole, leur préparation et leur utilisation thérapeutique.
FR2731224B1 (fr) * 1995-03-02 1997-05-30 Pf Medicament Nouveaux derives bi-tryptaminiques sulfonamides, leur procede de preparation et leur utilisation a titre de medicaments
GB9523462D0 (en) * 1995-11-16 1996-01-17 Merck Sharp & Dohme Therapeutic agents
US8022095B2 (en) 1996-08-16 2011-09-20 Pozen, Inc. Methods of treating headaches using 5-HT agonists in combination with long-acting NSAIDs
US7189753B1 (en) 1997-11-06 2007-03-13 Cady Roger K Preemptive prophylaxis of migraine
US6204274B1 (en) 1998-04-29 2001-03-20 American Home Products Corporation Indolyl derivatives as serotonergic agents
US6310066B1 (en) 1998-04-29 2001-10-30 American Home Products Corp. Antipsychotic indolyl derivatives
US6066637A (en) * 1998-06-19 2000-05-23 American Home Products Corporation Indolyl derivatives as serotonergic agents
US20060004029A1 (en) * 2002-08-30 2006-01-05 Akihiko Tsuruoka Nitrogen-containing aromatic derivatives
GB0302094D0 (en) 2003-01-29 2003-02-26 Pharmagene Lab Ltd EP4 receptor antagonists
JP4878285B2 (ja) * 2003-06-05 2012-02-15 エテルナ ツェンタリス ゲゼルシャフト ミット ベシュレンクテル ハフツング アポトーシス誘発作用を有するインドール誘導体
GB0324269D0 (en) 2003-10-16 2003-11-19 Pharmagene Lab Ltd EP4 receptor antagonists
DE602005020280D1 (de) * 2004-06-01 2010-05-12 Hoffmann La Roche 3-amino-1-arylpropyl-indole als monoamin-wiederaufnahmehemmer
WO2006129190A1 (en) * 2005-06-03 2006-12-07 Glenmark Pharmaceuticals Limited Process for the preparation of almotriptan
US20070112055A1 (en) * 2005-09-30 2007-05-17 Glenmark Pharmaceuticals Limited Crystalline forms of almotriptan and processes for their preparation
DE102006027229A1 (de) * 2006-06-09 2007-12-20 Grünenthal GmbH 1,3-Disubstituierte 4-Methyl-1H-pyrrol-2-carbonsäureamide und ihre Verwendung zur Herstellung von Arzneimitteln
WO2008049116A2 (en) 2006-10-19 2008-04-24 Auspex Pharmaceuticals, Inc. Substituted indoles
TWI321616B (en) 2007-03-27 2010-03-11 Coretronic Corp Centrifugal blower
CZ302424B6 (cs) * 2007-06-13 2011-05-11 Zentiva, A. S. Zpusob prípravy almotriptanu o vysoké cistote
US20100292290A1 (en) * 2007-08-02 2010-11-18 Vinayak Gore Novel process to prepare almotriptan
CN103724252A (zh) * 2012-10-12 2014-04-16 苏州四同医药科技有限公司 一种阿莫曲坦的制备方法
EP3766483A1 (en) 2019-07-19 2021-01-20 BioPharma Synergies, S. L. Orodispersible powder composition comprising a triptan

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2082175B (en) * 1980-08-12 1984-05-02 Glaxo Group Ltd Heterocyclic compounds
GR79215B (enExample) * 1982-06-07 1984-10-22 Glaxo Group Ltd
GB2162532B (en) * 1984-08-04 1988-08-03 Ritchie Swanson John Decontaminant wash composition
GB8431426D0 (en) * 1984-12-13 1985-01-23 Glaxo Group Ltd Chemical compounds
GB8719167D0 (en) * 1987-08-13 1987-09-23 Glaxo Group Ltd Chemical compounds
CZ288351B6 (en) * 1990-06-07 2001-05-16 Astrazeneca Ab Nitrogenous heterocyclic compound, process of its preparation and use as well as a medicament containing thereof

Also Published As

Publication number Publication date
MY113266A (en) 2002-01-31
CA2120028C (en) 1999-03-23
NZ254152A (en) 1996-12-20
DE10199016I2 (de) 2006-04-06
NO941019L (no) 1994-03-22
NL300053I1 (nl) 2001-11-01
DE10199016I1 (de) 2001-05-23
FI941413L (fi) 1994-03-25
CN1087629A (zh) 1994-06-08
HK1011680A1 (en) 1999-07-16
UA27818C2 (uk) 2000-10-16
CA2120028A1 (en) 1994-02-03
GB9216009D0 (en) 1992-09-09
AU4570793A (en) 1994-02-14
IL106387A0 (en) 1993-11-15
BR1100061A (pt) 2000-04-18
BR9305589A (pt) 1996-01-02
HU9400869D0 (en) 1994-06-28
ZA935316B (en) 1994-02-14
PL302917A1 (en) 1994-09-05
US5565447A (en) 1996-10-15
HU211243A9 (en) 1995-11-28
CZ66494A3 (en) 1994-12-15
JP2716585B2 (ja) 1998-02-18
SG48708A1 (en) 1998-05-18
JPH06511261A (ja) 1994-12-15
RU2117667C1 (ru) 1998-08-20
TW235297B (enExample) 1994-12-01
UY23624A1 (es) 1993-08-10
LU90758I2 (fr) 2001-06-11
MX9304524A (es) 1994-04-29
ATE177080T1 (de) 1999-03-15
WO1994002460A1 (en) 1994-02-03
DE69323712T2 (de) 1999-07-01
AU661190B2 (en) 1995-07-13
ECSP930953A (es) 1994-08-15
CZ282659B6 (cs) 1997-08-13
FI941413A0 (fi) 1994-03-25
NO941019D0 (no) 1994-03-22
GR3029915T3 (en) 1999-07-30
EG20340A (en) 1998-10-31
IL106387A (en) 1997-04-15
NO180231C (no) 1997-03-12
EP0605697A1 (en) 1994-07-13
NO180231B (no) 1996-12-02
CN1035179C (zh) 1997-06-18
FI109998B (fi) 2002-11-15
KR100191830B1 (ko) 1999-06-15
EP0605697B1 (en) 1999-03-03
DK0605697T3 (da) 1999-09-27
DE69323712D1 (de) 1999-04-08
HUT70518A (en) 1995-10-30
PL174352B1 (pl) 1998-07-31

Similar Documents

Publication Publication Date Title
NL300053I1 (nl) Indoolderivaten voor een behandeling van migraine.
AU671933B2 (en) The administration of monoamine acridine in cholinergic neuronal deficit states
RU94020400A (ru) Производные индола, способ их получения, фармацевтическая композиция, способ лечения головной боли
TR200100439T2 (tr) 1H-İmidazopiridin türevleri
ES2091615T3 (es) Derivados de indol fungicidas.
IE811831L (en) Indoles.
DK0795334T3 (da) Nye prodrugs til behandling af tumorer og betændelsessygdomme
ES538418A0 (es) Un derivado de indol-3-carboxamida
DE69332945D1 (de) Indol-derivat, verfahren zu dessen herstellung und dessen medizinische anwendung
HUP9900968A2 (hu) Herbicid hatású szubsztituált-3-aril-pirazol vegyületek, ezeket tartalmazó készítmények, eljárás alkalmazásukra valamint eljárás a vegyületek előállítására
YU140491A (sh) 6-supstituisani-tetrahidrobenz(c,d) indoli
AR023528A1 (es) Derivados de ciclobuten-3,4-diona, su preparacion y su aplicacion en terapeutica
TW336232B (en) Indol-3-yl propenoic acid derivatives for antagonizing NMDA(N-methyl-D-aspartate) and pharmaceutical compositions thereof
MY135358A (en) New process for the synthesis of (2s, 3as, 7as)-1-[(s)-alanyl]-octahydro-1h-indole-2-carboxylic acid compounds and application in the synthesis of perindopril
ES2056025A1 (es) Nuevos derivados de indol.
ATE197953T1 (de) Pyrrolo(4,3,2-de)chinolin-derivat
EP0782988A4 (en) INDOL DERIVATIVES
EP1325913A3 (en) Piperidinecarboxylic acid amide derivatives
TW349092B (en) Substituted indole derivatives