DE69323712T2 - Indol derivate zur behandlung von migräne - Google Patents

Indol derivate zur behandlung von migräne

Info

Publication number
DE69323712T2
DE69323712T2 DE69323712T DE69323712T DE69323712T2 DE 69323712 T2 DE69323712 T2 DE 69323712T2 DE 69323712 T DE69323712 T DE 69323712T DE 69323712 T DE69323712 T DE 69323712T DE 69323712 T2 DE69323712 T2 DE 69323712T2
Authority
DE
Germany
Prior art keywords
image
alkyl group
treating migraine
indol derivatives
migraine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69323712T
Other languages
English (en)
Other versions
DE69323712D1 (de
Inventor
Forner Dolors Fernandez
Duran Carles Puig
Soto Jose Prieto
Noverola Armando Vega
Mauri Jacinto Moragues
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Almirall SA
Original Assignee
Almirall Prodesfarma SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=10719423&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE69323712(T2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Almirall Prodesfarma SA filed Critical Almirall Prodesfarma SA
Application granted granted Critical
Publication of DE69323712D1 publication Critical patent/DE69323712D1/de
Publication of DE69323712T2 publication Critical patent/DE69323712T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/14—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
    • C07D209/16—Tryptamines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/06—Antimigraine agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biomedical Technology (AREA)
  • Public Health (AREA)
  • Pain & Pain Management (AREA)
  • Psychiatry (AREA)
  • Anesthesiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Processing Of Solid Wastes (AREA)
  • Fertilizers (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pyrane Compounds (AREA)
  • Steroid Compounds (AREA)
DE69323712T 1992-07-28 1993-07-19 Indol derivate zur behandlung von migräne Expired - Lifetime DE69323712T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB929216009A GB9216009D0 (en) 1992-07-28 1992-07-28 New indol derivatives
PCT/EP1993/001901 WO1994002460A1 (en) 1992-07-28 1993-07-19 Indol derivatives for the treatment of migraine

Publications (2)

Publication Number Publication Date
DE69323712D1 DE69323712D1 (de) 1999-04-08
DE69323712T2 true DE69323712T2 (de) 1999-07-01

Family

ID=10719423

Family Applications (2)

Application Number Title Priority Date Filing Date
DE2001199016 Active DE10199016I2 (de) 1992-07-28 1993-07-19 Indol derivate zur Behandlung von Migraene
DE69323712T Expired - Lifetime DE69323712T2 (de) 1992-07-28 1993-07-19 Indol derivate zur behandlung von migräne

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DE2001199016 Active DE10199016I2 (de) 1992-07-28 1993-07-19 Indol derivate zur Behandlung von Migraene

Country Status (33)

Country Link
US (1) US5565447A (de)
EP (1) EP0605697B1 (de)
JP (1) JP2716585B2 (de)
KR (1) KR100191830B1 (de)
CN (1) CN1035179C (de)
AT (1) ATE177080T1 (de)
BR (2) BR9305589A (de)
CA (1) CA2120028C (de)
CZ (1) CZ282659B6 (de)
DE (2) DE10199016I2 (de)
DK (1) DK0605697T3 (de)
EC (1) ECSP930953A (de)
EG (1) EG20340A (de)
FI (1) FI109998B (de)
GB (1) GB9216009D0 (de)
GR (1) GR3029915T3 (de)
HK (1) HK1011680A1 (de)
HU (2) HUT70518A (de)
IL (1) IL106387A (de)
LU (1) LU90758I2 (de)
MX (1) MX9304524A (de)
MY (1) MY113266A (de)
NL (1) NL300053I2 (de)
NO (1) NO180231C (de)
NZ (1) NZ254152A (de)
PL (1) PL174352B1 (de)
RU (1) RU2117667C1 (de)
SG (1) SG48708A1 (de)
TW (1) TW235297B (de)
UA (1) UA27818C2 (de)
UY (1) UY23624A1 (de)
WO (1) WO1994002460A1 (de)
ZA (1) ZA935316B (de)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2712591B1 (fr) * 1993-11-19 1996-02-09 Pf Medicament Nouvelles arylpipérazines dérivées d'indole, leur préparation et leur utilisation thérapeutique.
FR2731224B1 (fr) * 1995-03-02 1997-05-30 Pf Medicament Nouveaux derives bi-tryptaminiques sulfonamides, leur procede de preparation et leur utilisation a titre de medicaments
GB9523462D0 (en) * 1995-11-16 1996-01-17 Merck Sharp & Dohme Therapeutic agents
US8022095B2 (en) 1996-08-16 2011-09-20 Pozen, Inc. Methods of treating headaches using 5-HT agonists in combination with long-acting NSAIDs
US6310066B1 (en) 1998-04-29 2001-10-30 American Home Products Corp. Antipsychotic indolyl derivatives
US6204274B1 (en) 1998-04-29 2001-03-20 American Home Products Corporation Indolyl derivatives as serotonergic agents
US6066637A (en) * 1998-06-19 2000-05-23 American Home Products Corporation Indolyl derivatives as serotonergic agents
GB0302094D0 (en) 2003-01-29 2003-02-26 Pharmagene Lab Ltd EP4 receptor antagonists
GB0324269D0 (en) 2003-10-16 2003-11-19 Pharmagene Lab Ltd EP4 receptor antagonists
WO2006129190A1 (en) * 2005-06-03 2006-12-07 Glenmark Pharmaceuticals Limited Process for the preparation of almotriptan
US20070112055A1 (en) * 2005-09-30 2007-05-17 Glenmark Pharmaceuticals Limited Crystalline forms of almotriptan and processes for their preparation
DE102006027229A1 (de) * 2006-06-09 2007-12-20 Grünenthal GmbH 1,3-Disubstituierte 4-Methyl-1H-pyrrol-2-carbonsäureamide und ihre Verwendung zur Herstellung von Arzneimitteln
AU2007310949A1 (en) 2006-10-19 2008-04-24 Auspex Pharmaceuticals, Inc. Substituted indoles
TWI321616B (en) 2007-03-27 2010-03-11 Coretronic Corp Centrifugal blower
CZ302424B6 (cs) * 2007-06-13 2011-05-11 Zentiva, A. S. Zpusob prípravy almotriptanu o vysoké cistote
CN101842352A (zh) * 2007-08-02 2010-09-22 基因里克斯(英国)有限公司 新方法
CN103724252A (zh) * 2012-10-12 2014-04-16 苏州四同医药科技有限公司 一种阿莫曲坦的制备方法
EP3766483A1 (de) 2019-07-19 2021-01-20 BioPharma Synergies, S. L. Orodispergierbare pulverzusammensetzung mit einem triptan

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2082175B (en) * 1980-08-12 1984-05-02 Glaxo Group Ltd Heterocyclic compounds
GR79215B (de) * 1982-06-07 1984-10-22 Glaxo Group Ltd
GB2162532B (en) * 1984-08-04 1988-08-03 Ritchie Swanson John Decontaminant wash composition
GB8431426D0 (en) * 1984-12-13 1985-01-23 Glaxo Group Ltd Chemical compounds
GB8719167D0 (en) * 1987-08-13 1987-09-23 Glaxo Group Ltd Chemical compounds
YU48855B (sh) * 1990-06-07 2002-06-19 The Wellcome Foundation Limited Heterociklična jedinjenja i njihovi derivati koji su modifikatori dejstva 5-hidroksi-triptamina i postupak njihovog dobijanja

Also Published As

Publication number Publication date
AU4570793A (en) 1994-02-14
JPH06511261A (ja) 1994-12-15
DK0605697T3 (da) 1999-09-27
KR100191830B1 (ko) 1999-06-15
LU90758I2 (fr) 2001-06-11
SG48708A1 (en) 1998-05-18
FI941413A0 (fi) 1994-03-25
DE10199016I2 (de) 2006-04-06
UY23624A1 (es) 1993-08-10
CN1087629A (zh) 1994-06-08
IL106387A (en) 1997-04-15
HK1011680A1 (en) 1999-07-16
EP0605697A1 (de) 1994-07-13
MX9304524A (es) 1994-04-29
HU211243A9 (en) 1995-11-28
NO180231B (no) 1996-12-02
RU2117667C1 (ru) 1998-08-20
NO180231C (no) 1997-03-12
ECSP930953A (es) 1994-08-15
DE10199016I1 (de) 2001-05-23
TW235297B (de) 1994-12-01
CZ66494A3 (en) 1994-12-15
MY113266A (en) 2002-01-31
PL302917A1 (en) 1994-09-05
AU661190B2 (en) 1995-07-13
BR9305589A (pt) 1996-01-02
JP2716585B2 (ja) 1998-02-18
CA2120028A1 (en) 1994-02-03
WO1994002460A1 (en) 1994-02-03
CA2120028C (en) 1999-03-23
EP0605697B1 (de) 1999-03-03
NL300053I1 (nl) 2001-11-01
IL106387A0 (en) 1993-11-15
CZ282659B6 (cs) 1997-08-13
HUT70518A (en) 1995-10-30
PL174352B1 (pl) 1998-07-31
HU9400869D0 (en) 1994-06-28
GR3029915T3 (en) 1999-07-30
NO941019D0 (no) 1994-03-22
CN1035179C (zh) 1997-06-18
BR1100061A (pt) 2000-04-18
GB9216009D0 (en) 1992-09-09
NL300053I2 (nl) 2002-04-02
NZ254152A (en) 1996-12-20
UA27818C2 (uk) 2000-10-16
EG20340A (en) 1998-10-31
FI109998B (fi) 2002-11-15
ZA935316B (en) 1994-02-14
US5565447A (en) 1996-10-15
DE69323712D1 (de) 1999-04-08
NO941019L (no) 1994-03-22
ATE177080T1 (de) 1999-03-15
FI941413A (fi) 1994-03-25

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