NL178421C - Aminothiazoolderivaat met ontstekinggenezende en immunoresponsregulerende werking en farmaceutisch preparaat, dat een dergelijk aminothiazoolderivaat bevat. - Google Patents

Aminothiazoolderivaat met ontstekinggenezende en immunoresponsregulerende werking en farmaceutisch preparaat, dat een dergelijk aminothiazoolderivaat bevat.

Info

Publication number
NL178421C
NL178421C NLAANVRAGE7904337,A NL7904337A NL178421C NL 178421 C NL178421 C NL 178421C NL 7904337 A NL7904337 A NL 7904337A NL 178421 C NL178421 C NL 178421C
Authority
NL
Netherlands
Prior art keywords
aminothiazole derivative
sponsulating
immune
inflammatory
effect
Prior art date
Application number
NLAANVRAGE7904337,A
Other languages
English (en)
Dutch (nl)
Other versions
NL178421B (nl
NL7904337A (nl
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of NL7904337A publication Critical patent/NL7904337A/xx
Publication of NL178421B publication Critical patent/NL178421B/xx
Application granted granted Critical
Publication of NL178421C publication Critical patent/NL178421C/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/38Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D307/52Radicals substituted by nitrogen atoms not forming part of a nitro radical
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D277/00Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/32Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/38Nitrogen atoms
    • C07D277/42Amino or imino radicals substituted by hydrocarbon or substituted hydrocarbon radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D333/00Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/06Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
    • C07D333/14Radicals substituted by singly bound hetero atoms other than halogen
    • C07D333/20Radicals substituted by singly bound hetero atoms other than halogen by nitrogen atoms
    • FMECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F16ENGINEERING ELEMENTS AND UNITS; GENERAL MEASURES FOR PRODUCING AND MAINTAINING EFFECTIVE FUNCTIONING OF MACHINES OR INSTALLATIONS; THERMAL INSULATION IN GENERAL
    • F16BDEVICES FOR FASTENING OR SECURING CONSTRUCTIONAL ELEMENTS OR MACHINE PARTS TOGETHER, e.g. NAILS, BOLTS, CIRCLIPS, CLAMPS, CLIPS OR WEDGES; JOINTS OR JOINTING
    • F16B15/00Nails; Staples
    • F16B15/0023Nail plates
    • F16B2015/0076Nail plates with provisions for additional fastening means, e.g. hooks, holes for separate screws or nails, adhesive

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
NLAANVRAGE7904337,A 1978-06-02 1979-06-01 Aminothiazoolderivaat met ontstekinggenezende en immunoresponsregulerende werking en farmaceutisch preparaat, dat een dergelijk aminothiazoolderivaat bevat. NL178421C (nl)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US91183078A 1978-06-02 1978-06-02

Publications (3)

Publication Number Publication Date
NL7904337A NL7904337A (nl) 1979-12-04
NL178421B NL178421B (nl) 1985-10-16
NL178421C true NL178421C (nl) 1986-03-17

Family

ID=25430923

Family Applications (1)

Application Number Title Priority Date Filing Date
NLAANVRAGE7904337,A NL178421C (nl) 1978-06-02 1979-06-01 Aminothiazoolderivaat met ontstekinggenezende en immunoresponsregulerende werking en farmaceutisch preparaat, dat een dergelijk aminothiazoolderivaat bevat.

Country Status (36)

Country Link
JP (1) JPS5936988B2 (fr)
AR (1) AR226285A1 (fr)
AT (1) AT373248B (fr)
AU (1) AU511242B2 (fr)
BE (1) BE876732A (fr)
CA (1) CA1117949A (fr)
CH (1) CH639653A5 (fr)
CS (1) CS216927B2 (fr)
DD (1) DD144055A5 (fr)
DE (1) DE2922523C2 (fr)
DK (1) DK150068C (fr)
EG (1) EG14354A (fr)
ES (1) ES481220A1 (fr)
FI (1) FI68820C (fr)
FR (1) FR2427333A1 (fr)
GB (1) GB2022085B (fr)
GR (1) GR73142B (fr)
HK (1) HK66487A (fr)
HU (1) HU180045B (fr)
IE (1) IE48426B1 (fr)
IL (1) IL57450A (fr)
IT (1) IT1121238B (fr)
KE (1) KE3459A (fr)
LU (1) LU81349A1 (fr)
MY (1) MY8500318A (fr)
NL (1) NL178421C (fr)
NO (1) NO150760C (fr)
NZ (1) NZ190623A (fr)
PH (1) PH17020A (fr)
PL (1) PL117515B1 (fr)
PT (1) PT69718A (fr)
SE (1) SE438333B (fr)
SG (1) SG56184G (fr)
SU (1) SU843746A3 (fr)
YU (1) YU40997B (fr)
ZA (1) ZA792729B (fr)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0063575A4 (fr) * 1980-10-24 1983-02-14 Ronald Peter Hansen System de reduction de la poussiere.
WO1982002384A1 (fr) * 1981-01-08 1982-07-22 Sakano Isao Derives de n-(4-phenyl-2-thiazolyl) carbamate, procede de preparation et composition medicinale les contenant
JPS57136579A (en) * 1981-01-21 1982-08-23 Mitsui Toatsu Chem Inc Thiazolylurea derivative, its preparation, and pharmaceutical composition containing the same
JPS57116067A (en) * 1981-01-12 1982-07-19 Sankyo Kagaku Kk Novel 8-quinolinesulfonyl derivative, its synthesis and use
WO1982002383A1 (fr) * 1981-01-13 1982-07-22 Sakano Isao Nouveaux composes de thiazol, procede de preparation, et composition medicinale en contenant
WO1982002386A1 (fr) * 1981-01-13 1982-07-22 Sakano Isao Derives d'aminothiazoles, procede de preparation et composition medicinale les contenant
JPS57154175A (en) * 1981-03-16 1982-09-22 Mitsui Toatsu Chem Inc 2-thiazoleamine derivative, its preparation, and drug composition comprising it
DE3227329A1 (de) * 1982-07-22 1984-01-26 Basf Ag, 6700 Ludwigshafen Verfahren zur herstellung von 2-n,n-disubstituierten aminothiazolen
WO1986003203A1 (fr) * 1984-11-22 1986-06-05 Yoshitomi Pharmaceutical Industries, Ltd. Derives de thienylthiazole
FR2581063B1 (fr) * 1985-04-30 1987-07-17 Chauvin Blache Lab Amino-2 thiazoles n-substitues, leur procede de preparation et leur application en therapeutique
JPS63152368A (ja) * 1986-06-03 1988-06-24 Sumitomo Pharmaceut Co Ltd 新規なアミノアゾ−ル誘導体およびその酸付加塩
JPH075579B2 (ja) * 1986-09-01 1995-01-25 吉富製薬株式会社 アミノチアゾ−ル化合物
JPH0753666B2 (ja) * 1987-09-14 1995-06-07 久光製薬株式会社 置換ジフェニルチアゾール誘導体からなる抗炎症剤
DK0486543T3 (da) * 1989-08-10 1998-07-20 Commw Scient Ind Res Org Fremgangsmåde til fremstilling af en elektrosuspension af mikropartikler
DE69132293D1 (de) * 1991-03-07 2000-08-10 Hisamitsu Pharmaceutical Co Diphenylthiazolderivate mit antiinflammatorischer aktivität
FR2692893B1 (fr) * 1992-06-24 1994-09-02 Sanofi Elf Dérivés alkylamino ramifiés du thiazole, leurs procédés de préparation et les compositions pharmaceutiques qui les contiennent.
EP0772606A1 (fr) * 1994-07-27 1997-05-14 G.D. SEARLE & CO. Thiazoles substitues destines au traitement de l'inflammation
FR2754258B1 (fr) 1996-10-08 1998-12-31 Sanofi Sa Derives d'aminothiazole, leur procede de preparation et les compositions pharmaceutiques les contenant
ES2317889T3 (es) * 2000-03-01 2009-05-01 Janssen Pharmaceutica Nv Derivados de tiazolilo 2,4-disustituido.
WO2003015777A1 (fr) * 2001-08-13 2003-02-27 Lion Bioscience Ag Composes de liaison au recepteur nucleaire nr1h4
WO2003027085A2 (fr) * 2001-09-26 2003-04-03 Bayer Pharmaceuticals Corporation Thiazoles 3-pyridyle ou 4-isoquinolinyle utilises comme inhibiteurs de lyase c17,20
MXPA04006709A (es) 2002-01-11 2004-10-04 Sankyo Co Derivados de aminoalcohol o derivados de acido fosfonico y composiciones farmaceuticas que los contienen.
EP1555264A1 (fr) * 2004-01-15 2005-07-20 Sireen AG Hétérocycles à cinq chaínons comme inhibiteurs de la famille des SRC proteines kinases
WO2005079788A1 (fr) 2004-02-24 2005-09-01 Sankyo Company, Limited Composé d’alcool aminé
AP2358A (en) * 2005-05-09 2012-01-30 Achillion Pharmaceuticals Inc Thiazole compounds and methods of use.
BRPI0706621A2 (pt) 2006-01-18 2011-04-05 Amgen Inc composto, composição farmacêutica, métodos para tratar um distúrbio mediado por quinase em um mamìfero e para tratar um distúrbio relacionado com a proliferação em um mamìfero, e , uso do composto
CA2692713A1 (fr) 2007-07-17 2009-01-22 Amgen Inc. Modulateurs heterocycliques de pkb
WO2009011871A2 (fr) 2007-07-17 2009-01-22 Amgen Inc. Thiadiazoles modulateurs de l'activité de pkb
WO2012170931A2 (fr) 2011-06-10 2012-12-13 Calcimedica, Inc. Composés qui modulent le calcium intracellulaire
US20130143927A1 (en) * 2011-06-10 2013-06-06 Calcimedica, Inc. Compounds that modulate intracellular calcium
WO2013059677A1 (fr) 2011-10-19 2013-04-25 Calcimedica, Inc. Composés qui modulent le calcium intracellulaire
CN110590785B (zh) * 2019-09-23 2021-02-02 武汉大学 一种氨基噻唑类化合物及其制备方法与抗肠道病毒71型的应用

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3458526A (en) * 1966-09-26 1969-07-29 Upjohn Co Certain 2-amino-4,5-bis(p-methoxyphenyl)thiazoles

Also Published As

Publication number Publication date
IT7923228A0 (it) 1979-06-01
PH17020A (en) 1984-05-11
HU180045B (en) 1983-01-28
ATA401679A (de) 1983-05-15
SU843746A3 (ru) 1981-06-30
NO150760C (no) 1984-12-12
ES481220A1 (es) 1980-09-01
JPS5936988B2 (ja) 1984-09-06
DE2922523C2 (de) 1982-10-21
JPS54160369A (en) 1979-12-19
NO791831L (no) 1979-12-04
IL57450A0 (en) 1979-09-30
LU81349A1 (fr) 1979-12-07
GR73142B (fr) 1984-02-09
YU40997B (en) 1986-10-31
KE3459A (en) 1984-10-12
IL57450A (en) 1982-11-30
SE7904798L (sv) 1979-12-03
DE2922523A1 (de) 1979-12-06
NL178421B (nl) 1985-10-16
FR2427333B1 (fr) 1983-05-20
PL216030A1 (fr) 1980-03-10
FR2427333A1 (fr) 1979-12-28
NL7904337A (nl) 1979-12-04
HK66487A (en) 1987-09-25
DD144055A5 (de) 1980-09-24
AR226285A1 (es) 1982-06-30
AT373248B (de) 1983-12-27
DK177679A (da) 1979-12-03
EG14354A (en) 1984-06-30
FI68820C (fi) 1985-11-11
YU128879A (en) 1982-10-31
CS216927B2 (en) 1982-12-31
CA1117949A (fr) 1982-02-09
ZA792729B (en) 1981-03-25
AU4763479A (en) 1979-12-06
PL117515B1 (en) 1981-08-31
PT69718A (en) 1979-07-01
SE438333B (sv) 1985-04-15
GB2022085A (en) 1979-12-12
CH639653A5 (fr) 1983-11-30
NO150760B (no) 1984-09-03
MY8500318A (en) 1985-12-31
AU511242B2 (en) 1980-08-07
DK150068C (da) 1987-06-29
IT1121238B (it) 1986-03-26
BE876732A (fr) 1979-12-03
FI791754A (fi) 1979-11-26
IE48426B1 (en) 1985-01-23
GB2022085B (en) 1983-01-12
FI68820B (fi) 1985-07-31
IE791069L (en) 1979-12-02
NZ190623A (en) 1984-07-06
DK150068B (da) 1986-12-01
SG56184G (en) 1985-03-08

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A1A A request for search or an international-type search has been filed
BB A search report has been drawn up
BC A request for examination has been filed
A85 Still pending on 85-01-01
V1 Lapsed because of non-payment of the annual fee