MY169816A - Ophthalmic solution comprising diquafosol - Google Patents
Ophthalmic solution comprising diquafosolInfo
- Publication number
- MY169816A MY169816A MYPI2014002576A MYPI2014002576A MY169816A MY 169816 A MY169816 A MY 169816A MY PI2014002576 A MYPI2014002576 A MY PI2014002576A MY PI2014002576 A MYPI2014002576 A MY PI2014002576A MY 169816 A MY169816 A MY 169816A
- Authority
- MY
- Malaysia
- Prior art keywords
- course
- ophthalmic solution
- production
- chelating agent
- diquafosol ophthalmic
- Prior art date
Links
- NMLMACJWHPHKGR-NCOIDOBVSA-N P(1),P(4)-bis(uridin-5'-yl) tetraphosphate Chemical compound N1([C@@H]2O[C@@H]([C@H]([C@H]2O)O)COP(O)(=O)OP(O)(=O)OP(O)(=O)OP(O)(=O)OC[C@@H]2[C@H]([C@H]([C@@H](O2)N2C(NC(=O)C=C2)=O)O)O)C=CC(=O)NC1=O NMLMACJWHPHKGR-NCOIDOBVSA-N 0.000 title abstract 6
- 229950003529 diquafosol Drugs 0.000 title abstract 6
- 229940054534 ophthalmic solution Drugs 0.000 title abstract 6
- 239000002997 ophthalmic solution Substances 0.000 title abstract 6
- 238000001914 filtration Methods 0.000 abstract 5
- 238000004519 manufacturing process Methods 0.000 abstract 5
- 239000002738 chelating agent Substances 0.000 abstract 4
- 230000001954 sterilising effect Effects 0.000 abstract 3
- 238000004659 sterilization and disinfection Methods 0.000 abstract 3
- 206010015946 Eye irritation Diseases 0.000 abstract 2
- 231100000013 eye irritation Toxicity 0.000 abstract 2
- 239000003755 preservative agent Substances 0.000 abstract 2
- 230000002335 preservative effect Effects 0.000 abstract 2
- 230000015572 biosynthetic process Effects 0.000 abstract 1
- 230000015556 catabolic process Effects 0.000 abstract 1
- 238000006731 degradation reaction Methods 0.000 abstract 1
- 230000006866 deterioration Effects 0.000 abstract 1
- 239000002244 precipitate Substances 0.000 abstract 1
- 239000000243 solution Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7084—Compounds having two nucleosides or nucleotides, e.g. nicotinamide-adenine dinucleotide, flavine-adenine dinucleotide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/12—Carboxylic acids; Salts or anhydrides thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
- A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
- A61K47/183—Amino acids, e.g. glycine, EDTA or aspartame
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/24—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing atoms other than carbon, hydrogen, oxygen, halogen, nitrogen or sulfur, e.g. cyclomethicone or phospholipids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0048—Eye, e.g. artificial tears
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/04—Artificial tears; Irrigation solutions
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Molecular Biology (AREA)
- Ophthalmology & Optometry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2012069157 | 2012-03-26 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MY169816A true MY169816A (en) | 2019-05-16 |
Family
ID=49259901
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MYPI2014002576A MY169816A (en) | 2012-03-26 | 2013-03-25 | Ophthalmic solution comprising diquafosol |
Country Status (26)
| Country | Link |
|---|---|
| US (4) | US9486529B2 (esLanguage) |
| EP (2) | EP3431092A1 (esLanguage) |
| JP (6) | JP5625081B2 (esLanguage) |
| KR (5) | KR20200096708A (esLanguage) |
| CN (2) | CN113018259A (esLanguage) |
| AU (3) | AU2013241507A1 (esLanguage) |
| BR (1) | BR112014023402B1 (esLanguage) |
| CA (1) | CA2868390C (esLanguage) |
| DK (1) | DK2832359T3 (esLanguage) |
| EA (1) | EA028848B1 (esLanguage) |
| ES (1) | ES2702575T3 (esLanguage) |
| GE (1) | GEP20166470B (esLanguage) |
| HK (1) | HK1204922A1 (esLanguage) |
| HU (1) | HUE041671T2 (esLanguage) |
| IN (1) | IN2014DN08632A (esLanguage) |
| MX (1) | MX353874B (esLanguage) |
| MY (1) | MY169816A (esLanguage) |
| NZ (1) | NZ631041A (esLanguage) |
| PH (1) | PH12014501955B1 (esLanguage) |
| PL (1) | PL2832359T3 (esLanguage) |
| PT (1) | PT2832359T (esLanguage) |
| SG (2) | SG11201405799TA (esLanguage) |
| TR (1) | TR201820073T4 (esLanguage) |
| TW (4) | TWI723722B (esLanguage) |
| UA (1) | UA113981C2 (esLanguage) |
| WO (1) | WO2013146649A1 (esLanguage) |
Families Citing this family (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2750229B2 (ja) | 1991-05-30 | 1998-05-13 | 信越石英株式会社 | 大型軽量化反射鏡 |
| JP2750234B2 (ja) | 1991-12-25 | 1998-05-13 | 信越石英株式会社 | シリカ質軽量反射鏡の製造方法 |
| IN2014DN08632A (esLanguage) | 2012-03-26 | 2015-05-22 | Santen Pharmaceutical Co Ltd | |
| EP3093019B1 (en) | 2014-01-10 | 2021-05-26 | Santen Pharmaceutical Co., Ltd | Pharmaceutical composition containing pyridylamino acetic acid compound |
| JP6104433B2 (ja) * | 2015-06-05 | 2017-03-29 | 参天製薬株式会社 | 水性点眼液 |
| CA2971689C (en) | 2014-12-25 | 2020-11-03 | Santen Pharmaceutical Co., Ltd. | Aqueous ophthalmic solution |
| CN113143948A (zh) * | 2015-06-05 | 2021-07-23 | 参天制药株式会社 | 以向佩戴有软性隐形眼镜的干眼症患者的眼中滴入的方式使用为特征的干眼症治疗剂 |
| KR102116170B1 (ko) | 2015-06-29 | 2020-05-27 | 야마사 쇼유 가부시키가이샤 | P1, p4-비스(5''-우리딜)테트라포스페이트 결정의 보관 방법 |
| JP6688057B2 (ja) * | 2015-12-01 | 2020-04-28 | 日水製薬株式会社 | グラム染色用後染色試液及びグラム染色方法 |
| PH12020551313B1 (en) * | 2018-02-28 | 2024-02-28 | Santen Pharmaceutical Co Ltd | Ophthalmic composition comprising diquafosol and cationic polymer |
| CN108403625A (zh) * | 2018-04-11 | 2018-08-17 | 东莞解石医药科技有限公司 | 一种含有螯合剂的地夸磷索四钠滴眼液 |
| MX2021001707A (es) * | 2018-08-30 | 2021-04-19 | Eyevance Pharmaceuticals Llc | Formulaciones de lubricantes oculares. |
| KR20240049646A (ko) * | 2019-08-27 | 2024-04-16 | 산텐 세이야꾸 가부시키가이샤 | 디쿠아포솔 또는 그 염 및 폴리비닐피롤리돈을 함유하는 수성 안과용 조성물 |
| CN113720924B (zh) * | 2020-05-25 | 2025-01-10 | 南京帝昌医药科技有限公司 | 一种地夸磷索四钠的含量及有关物质检测方法 |
| WO2022107791A1 (ja) * | 2020-11-18 | 2022-05-27 | 参天製薬株式会社 | ポリヘキサメチレンビグアナイドまたはその塩を含有する水性点眼液 |
| JPWO2022107790A1 (esLanguage) * | 2020-11-18 | 2022-05-27 | ||
| KR102548710B1 (ko) | 2020-12-24 | 2023-06-28 | 주식회사 종근당 | 디쿠아포솔 또는 이의 약제학적으로 허용가능한 염과 토코페롤을 함유하는 건성안 예방 또는 치료용 약제학적 조성물 |
| CN112933040A (zh) * | 2021-02-04 | 2021-06-11 | 合肥博思科创医药科技有限公司 | 一种舒更葡糖钠注射液的制备方法 |
| KR102794468B1 (ko) * | 2022-04-04 | 2025-04-14 | 서울대학교산학협력단 | 감미 억제용 조성물 및 식품의 감미 억제 방법 |
| WO2023195718A1 (ko) * | 2022-04-04 | 2023-10-12 | 서울대학교산학협력단 | 감미 억제용 조성물 및 식품의 감미 억제 방법 |
| JP7735925B2 (ja) * | 2022-05-02 | 2025-09-09 | 株式会社三洋物産 | 遊技機 |
| CN116019767A (zh) * | 2023-01-12 | 2023-04-28 | 上海阿尔福斯医药科技有限公司 | 眼用制剂及其制备方法 |
| CN117838628B (zh) * | 2024-03-01 | 2024-05-28 | 广州市桐晖药业有限公司 | 一种地夸磷索钠滴眼液及其制备方法 |
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| JPH075456B2 (ja) * | 1988-10-01 | 1995-01-25 | 参天製薬株式会社 | 点眼液 |
| JP2530491B2 (ja) | 1988-12-20 | 1996-09-04 | 参天製薬株式会社 | ヒアルロン酸点眼液 |
| TW200402B (esLanguage) | 1990-08-13 | 1993-02-21 | Senju Pharma Co | |
| US5504113A (en) | 1994-03-02 | 1996-04-02 | Allergan, Inc. | Enhancement of benzalkonium chloride preservative activity in formulations containing an incompatible drug |
| US5900407A (en) | 1997-02-06 | 1999-05-04 | Inspire Pharmaceuticals, Inc. | Method of treating dry eye disease with uridine triphosphates and related compounds |
| US6348589B1 (en) | 1997-02-06 | 2002-02-19 | Inspire Pharmaceuticals, Inc. | Certain dinucleotides and their use as modulators of mucociliary clearance and ciliary beat frequency |
| DK1012154T3 (da) | 1997-07-25 | 2004-07-26 | Inspire Pharmaceuticals Inc | Salte af di(uridin-5'-tetraphosphat), fremgangsmåde til fremstilling og anvendelser deraf |
| KR19990074047A (ko) | 1998-03-03 | 1999-10-05 | 김수복 | 콘택트렌즈용 세척, 소독 및 보존제 조성물 |
| DE69932313T2 (de) | 1998-08-21 | 2007-07-19 | Senju Pharmaceutical Co., Ltd. | Wässerige flüssige zubereitungen |
| JP4880808B2 (ja) * | 1999-11-15 | 2012-02-22 | 久光製薬株式会社 | 人工涙液型点眼剤組成物 |
| JP4003008B2 (ja) * | 2000-05-30 | 2007-11-07 | 参天製薬株式会社 | 角膜上皮伸展促進剤 |
| KR100832821B1 (ko) * | 2000-05-30 | 2008-05-28 | 산텐 세이야꾸 가부시키가이샤 | 각막 상피 신장 촉진제 |
| US6555675B2 (en) | 2000-08-21 | 2003-04-29 | Inspire Pharmaceuticals, Inc. | Dinucleoside polyphosphate compositions and their therapuetic use as purinergic receptor agonists |
| US6583181B1 (en) | 2000-11-22 | 2003-06-24 | Lonza Inc. | Antimicrobial quaternary ammonium compositions with reduced ocular irritation |
| JP2003160491A (ja) * | 2001-09-11 | 2003-06-03 | Santen Pharmaceut Co Ltd | ジウリジンリン酸含有点眼液 |
| CN1228053C (zh) * | 2001-09-11 | 2005-11-23 | 参天制药株式会社 | 含有二尿苷磷酸的滴眼液 |
| WO2003030892A1 (en) | 2001-10-11 | 2003-04-17 | Alcon, Inc. | Methods for treating dry eye |
| RU2322980C2 (ru) | 2003-04-14 | 2008-04-27 | Уайт Холдингз Корпорейшн | Композиции, содержащие пиперациллин и тазобактам, применимые для инъекции |
| JP4806956B2 (ja) | 2004-04-20 | 2011-11-02 | 大正製薬株式会社 | 点眼用液剤 |
| US20060073172A1 (en) | 2004-10-01 | 2006-04-06 | Schneider L W | Stabilized ophthalmic solution for the treatment of glaucoma and lowering intraocular pressure |
| PT1841432E (pt) | 2004-12-02 | 2010-10-25 | Venus Remedies Ltd | Composições para combater a resistência aos antibióticos mediada pela beta-lactamase usando inibidores da betalactamase úteis para injecção |
| KR100870104B1 (ko) * | 2005-11-28 | 2008-11-26 | 주식회사 머젠스 | 안구건조증 치료 및 예방용 조성물 |
| JP4168071B2 (ja) | 2005-12-08 | 2008-10-22 | 興和株式会社 | 点眼用組成物 |
| JP2008247828A (ja) | 2007-03-30 | 2008-10-16 | Wakamoto Pharmaceut Co Ltd | ラタノプロストを含有する水性医薬組成物。 |
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| CN100534423C (zh) * | 2007-11-30 | 2009-09-02 | 张咏梅 | 一种保质期长的氯霉素滴眼液及其制备方法 |
| US8119112B2 (en) | 2008-01-31 | 2012-02-21 | Bausch & Lomb Incorporated | Ophthalmic compositions with an amphoteric surfactant and hyaluronic acid |
| CN101461778A (zh) * | 2009-01-06 | 2009-06-24 | 河北科技大学 | 不含抑菌剂的盐酸环丙沙星滴眼液及其制备方法 |
| US20100190734A1 (en) * | 2009-01-23 | 2010-07-29 | Romulus Kimbro Brazzell | Method of treating dry eye disease with azithromycin |
| CN102100693A (zh) * | 2009-12-16 | 2011-06-22 | 沈阳兴齐制药有限公司 | 一种含有肌肽的人工泪液及其制备方法 |
| KR20110104367A (ko) | 2010-03-16 | 2011-09-22 | 삼천당제약주식회사 | 무보존제 안과용 조성물 |
| WO2012012640A1 (en) | 2010-07-21 | 2012-01-26 | Cumberland Pharmaceuticals, Inc. | Acetycysteine compositions and methods of use thereof |
| CN106729718A (zh) | 2010-09-10 | 2017-05-31 | 参天制药株式会社 | 以组合p2y2受体激动剂和透明质酸或其盐为特征的干眼症治疗剂 |
| MX2013007502A (es) | 2010-12-28 | 2013-08-01 | Santen Pharmaceutical Co Ltd | Solucion oftalmica que comprende diquafosol, metodo para producir la misma, y metodo para inhibir la formacion de precipitado insoluble. |
| EP2696876A4 (en) * | 2011-04-12 | 2014-09-03 | R Tech Ueno Ltd | AQUEOUS OPHTHALMIC COMPOSITION |
| JP2015514705A (ja) | 2012-03-26 | 2015-05-21 | ディラフォール・アクチボラゲットＤｉｌａｆｏｒ Ａｂ | 分娩停止の処置のための方法 |
| IN2014DN08632A (esLanguage) | 2012-03-26 | 2015-05-22 | Santen Pharmaceutical Co Ltd |
-
2013
- 2013-03-25 IN IN8632DEN2014 patent/IN2014DN08632A/en unknown
- 2013-03-25 SG SG11201405799TA patent/SG11201405799TA/en unknown
- 2013-03-25 NZ NZ631041A patent/NZ631041A/en not_active IP Right Cessation
- 2013-03-25 SG SG10201607872PA patent/SG10201607872PA/en unknown
- 2013-03-25 CA CA2868390A patent/CA2868390C/en active Active
- 2013-03-25 KR KR1020207022714A patent/KR20200096708A/ko not_active Ceased
- 2013-03-25 MY MYPI2014002576A patent/MY169816A/en unknown
- 2013-03-25 TW TW109100132A patent/TWI723722B/zh active
- 2013-03-25 KR KR1020187037979A patent/KR20190002751A/ko not_active Ceased
- 2013-03-25 KR KR1020157004372A patent/KR101875845B1/ko not_active Ceased
- 2013-03-25 ES ES13770386T patent/ES2702575T3/es active Active
- 2013-03-25 BR BR112014023402-7A patent/BR112014023402B1/pt not_active IP Right Cessation
- 2013-03-25 CN CN202110358504.0A patent/CN113018259A/zh active Pending
- 2013-03-25 TR TR2018/20073T patent/TR201820073T4/tr unknown
- 2013-03-25 EP EP18193430.8A patent/EP3431092A1/en not_active Withdrawn
- 2013-03-25 KR KR1020147028142A patent/KR101536885B1/ko not_active Ceased
- 2013-03-25 DK DK13770386.4T patent/DK2832359T3/en active
- 2013-03-25 PT PT13770386T patent/PT2832359T/pt unknown
- 2013-03-25 PL PL13770386T patent/PL2832359T3/pl unknown
- 2013-03-25 TW TW106124911A patent/TWI692364B/zh active
- 2013-03-25 KR KR1020187018799A patent/KR101935484B1/ko not_active Ceased
- 2013-03-25 EA EA201491771A patent/EA028848B1/ru unknown
- 2013-03-25 US US14/386,169 patent/US9486529B2/en not_active Expired - Fee Related
- 2013-03-25 TW TW109124203A patent/TWI757799B/zh active
- 2013-03-25 TW TW102110422A patent/TWI625135B/zh active
- 2013-03-25 CN CN201380016616.1A patent/CN104203254A/zh active Pending
- 2013-03-25 UA UAA201411576A patent/UA113981C2/uk unknown
- 2013-03-25 WO PCT/JP2013/058519 patent/WO2013146649A1/ja not_active Ceased
- 2013-03-25 JP JP2013062270A patent/JP5625081B2/ja active Active
- 2013-03-25 EP EP13770386.4A patent/EP2832359B1/en active Active
- 2013-03-25 GE GEAP201313609A patent/GEP20166470B/en unknown
- 2013-03-25 HU HUE13770386A patent/HUE041671T2/hu unknown
- 2013-03-25 AU AU2013241507A patent/AU2013241507A1/en not_active Abandoned
- 2013-03-25 HK HK15105452.3A patent/HK1204922A1/xx unknown
- 2013-03-25 MX MX2014011468A patent/MX353874B/es active IP Right Grant
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2014
- 2014-04-14 JP JP2014082821A patent/JP6126041B2/ja active Active
- 2014-09-01 PH PH12014501955A patent/PH12014501955B1/en unknown
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2016
- 2016-02-23 AU AU2016201111A patent/AU2016201111A1/en not_active Withdrawn
- 2016-02-23 AU AU2016201110A patent/AU2016201110B2/en not_active Ceased
- 2016-10-10 US US15/289,273 patent/US10071113B2/en active Active
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2017
- 2017-04-05 JP JP2017075167A patent/JP6389544B2/ja active Active
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2018
- 2018-02-07 JP JP2018020154A patent/JP6483299B2/ja active Active
- 2018-08-14 US US16/103,328 patent/US10632139B2/en not_active Expired - Fee Related
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2019
- 2019-02-12 JP JP2019022692A patent/JP7042762B2/ja active Active
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2020
- 2020-03-16 US US16/819,974 patent/US11166974B2/en not_active Expired - Fee Related
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2022
- 2022-03-14 JP JP2022039183A patent/JP7447176B2/ja active Active
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