MY136593A - Cyclic peptide antifungal agents and process for preparation thereof - Google Patents

Cyclic peptide antifungal agents and process for preparation thereof

Info

Publication number
MY136593A
MY136593A MYPI93000458A MYPI9300458A MY136593A MY 136593 A MY136593 A MY 136593A MY PI93000458 A MYPI93000458 A MY PI93000458A MY PI9300458 A MYPI9300458 A MY PI9300458A MY 136593 A MY136593 A MY 136593A
Authority
MY
Malaysia
Prior art keywords
hydrogen
preparation
antifungal agents
cyclic peptide
hydroxy
Prior art date
Application number
MYPI93000458A
Other languages
English (en)
Inventor
Frederick Joseph Burkhardt
Manuel Debono
Jeffrey Scott Nissen
William Wilson Turner Jr
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of MY136593A publication Critical patent/MY136593A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/64—Cyclic peptides containing only normal peptide links
    • C07K7/66—Gramicidins S, C; Tyrocidins A, B, C; Related peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/50—Cyclic peptides containing at least one abnormal peptide link
    • C07K7/54—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring
    • C07K7/56—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring the cyclisation not occurring through 2,4-diamino-butanoic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Communicable Diseases (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Virology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Steroid Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
MYPI93000458A 1992-03-19 1993-03-15 Cyclic peptide antifungal agents and process for preparation thereof MY136593A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US85411792A 1992-03-19 1992-03-19
US99239092A 1992-12-16 1992-12-16

Publications (1)

Publication Number Publication Date
MY136593A true MY136593A (en) 2008-10-31

Family

ID=27127211

Family Applications (1)

Application Number Title Priority Date Filing Date
MYPI93000458A MY136593A (en) 1992-03-19 1993-03-15 Cyclic peptide antifungal agents and process for preparation thereof

Country Status (25)

Country Link
EP (1) EP0561639B1 (forum.php)
JP (3) JP3519754B2 (forum.php)
KR (1) KR100256036B1 (forum.php)
CN (1) CN1036715C (forum.php)
AT (1) ATE217635T1 (forum.php)
AU (2) AU3534193A (forum.php)
BR (1) BR9301232A (forum.php)
CA (1) CA2091663C (forum.php)
CZ (1) CZ288974B6 (forum.php)
DE (2) DE122008000006I2 (forum.php)
DK (1) DK0561639T3 (forum.php)
ES (1) ES2174843T3 (forum.php)
FI (1) FI118768B (forum.php)
HU (2) HU225783B1 (forum.php)
IL (3) IL122315A (forum.php)
LU (1) LU91406I2 (forum.php)
MX (1) MX9301457A (forum.php)
MY (1) MY136593A (forum.php)
NL (1) NL300334I2 (forum.php)
NO (1) NO930948L (forum.php)
NZ (3) NZ247149A (forum.php)
PT (1) PT561639E (forum.php)
RU (1) RU2129562C1 (forum.php)
TW (1) TW264477B (forum.php)
YU (1) YU49108B (forum.php)

Families Citing this family (46)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5430018A (en) * 1991-10-17 1995-07-04 Merck & Co., Inc. Cyclohexapeptide with basic nitrogen containing alkylamide groups
CZ288974B6 (cs) * 1992-03-19 2001-10-17 Eli Lilly And Company Acylový derivát echinocandinu, způsob jeho přípravy, farmaceutický prostředek s jeho obsahem a jeho pouľití
US6743777B1 (en) 1992-03-19 2004-06-01 Eli Lilly And Company Cyclic peptide antifungal agents and process for preparation thereof
US5378804A (en) * 1993-03-16 1995-01-03 Merck & Co., Inc. Aza cyclohexapeptide compounds
AU674233B2 (en) * 1993-05-04 1996-12-12 Merck & Co., Inc. Cyclohexapeptidyl aminoalkyl ethers
US5948753A (en) * 1993-05-04 1999-09-07 Merck & Co., Inc. Cyclohexapeptidyl propanolamine compounds
WO1995008341A1 (en) * 1993-09-22 1995-03-30 Merck & Co., Inc. Antifungal and anti-pneumocystis compounds, compositions containing such compounds, and methods of use
US5514651A (en) * 1994-09-16 1996-05-07 Merck & Co., Inc. Aza cyclohexapeptide compounds
US5516757A (en) * 1994-09-16 1996-05-14 Merck & Co., Inc. Semi-synthetic lipopeptides, compositions containing said lipopeptides, and methods of use
EP0781141B1 (en) * 1994-09-16 2002-09-04 Merck & Co. Inc. Aza cyclohexapeptide compounds
MX9702531A (es) * 1994-10-07 1997-06-28 Fujisawa Pharmaceutical Co Compuesto nuevo.
US5516756A (en) * 1994-10-31 1996-05-14 Merck & Co., Inc. Aza cyclohexapeptide compounds
DE69615535T2 (de) * 1995-01-26 2002-05-02 Merck & Co., Inc. Neue fungizide cyclohexapeptide
US5646111A (en) * 1995-04-07 1997-07-08 Eli Lilly And Company Cyclic peptide antifungal Agents
US5652213A (en) * 1995-05-26 1997-07-29 Eli Lilly And Company Cyclic peptide antifungal agents
US5786325A (en) * 1995-05-26 1998-07-28 Eli Lilly And Company Cyclic peptide antifungal agents and methods of making and using
US5629290A (en) * 1995-05-26 1997-05-13 Eli Lilly And Company Cyclic peptide antifungal agents
US5618787A (en) * 1995-05-26 1997-04-08 Eli Lilly And Company Cyclic peptide antifungal agents
US5629289A (en) * 1995-07-25 1997-05-13 Eli Lilly And Company Cyclic peptide antifungal agents
US5693611A (en) * 1996-02-01 1997-12-02 Eli Lilly And Company Cyclic peptide antifungal agents
JP2001503015A (ja) * 1996-02-01 2001-03-06 イーライ・リリー・アンド・カンパニー 環状ペプチド抗真菌剤
JPH09227422A (ja) * 1996-02-12 1997-09-02 Rolic Ag シクロペンチル誘導体
US5696084A (en) * 1996-08-16 1997-12-09 Abbott Laboratories Amino-lipopetide antifungal agents
AUPO381496A0 (en) * 1996-11-25 1996-12-19 Fujisawa Pharmaceutical Co., Ltd. New compound
UA72200C2 (uk) 1997-12-10 2005-02-15 Авентіс Фарма С.А. Похідні ехінокандину, спосіб їх одержання, їх застосування, проміжні сполуки та фармацевтична композиція
AU2003200556B2 (en) * 1997-12-10 2005-12-01 Novexel Echinocandin derivative and their preparation method
FR2784993B1 (fr) * 1998-10-26 2002-10-31 Hoechst Marion Roussel Inc Nouveaux derives de l'echinocandine, leur procede de preparation et leur application comme fongicides
AUPP172898A0 (en) * 1998-02-09 1998-03-05 Fujisawa Pharmaceutical Co., Ltd. New compound
WO1999047551A1 (en) * 1998-03-16 1999-09-23 Fujisawa Pharmaceutical Co., Ltd. Wf14573 or its salt, production thereof and use thereof
EP1107981B1 (en) 1998-08-20 2005-01-26 Eli Lilly & Company Synthesis of ring-modified cyclic peptide analogs
KR20010101151A (ko) 1998-12-09 2001-11-14 피터 지. 스트링거 에키노칸딘 시클로펩티드 화합물의 정제
DE19907904A1 (de) 1999-02-24 2000-08-31 Clariant Gmbh Verfahren zur Herstellung von [1,1':4',1"]-Terphenylverbindungen
IL145188A0 (en) 1999-03-03 2002-06-30 Lilly Co Eli Processes for making pharmaceutical oral ecb formulations and compositions
JP4936595B2 (ja) * 1999-03-03 2012-05-23 イーライ リリー アンド カンパニー ミセル形成界面活性剤を含有するエキノカンジン薬学的処方物
HK1040088B (en) 1999-03-03 2004-04-16 Eli Lilly And Company Echinocandin/carbohydrate complexes
KR20020002476A (ko) 1999-03-03 2002-01-09 피터 지. 스트링거 결정질 에키노칸딘 암모늄염의 형성 및 음이온 교환
ATE302184T1 (de) * 2000-02-18 2005-09-15 Meiji Seika Kaisha Phenoxyalkylaminderivate als agonisten des opioid-delta rezeptors
FR2833596B1 (fr) * 2001-12-14 2005-02-18 Aventis Pharma Sa Procede de preparation de derives d'echinocandine
US6991800B2 (en) 2002-06-13 2006-01-31 Vicuron Pharmaceuticals Inc. Antifungal parenteral products
CA2524235A1 (en) * 2003-04-30 2004-11-18 The Institutes For Pharmaceutical Discovery, Llc Phenyl substituted carboxylic acids as inhibitors of protein tyrosine phosphatase-1b
KR101551207B1 (ko) * 2008-09-04 2015-09-08 롬엔드하스전자재료코리아유한회사 신규한 유기 발광 화합물 및 이를 발광재료로서 채용하고 있는 유기 발광 소자
CN102464704B (zh) * 2010-11-05 2013-12-11 上海医药工业研究院 一种化合物及其制备方法和用途
MX2014011299A (es) * 2012-03-19 2015-05-11 Cidara Therapeutics Inc Regimenes de dosificacion para compuestos de la clase de las equinocandinas.
ES2694561T3 (es) 2015-02-23 2018-12-21 Selectchemie Ag Composición de anidulafungina
JP6866583B2 (ja) * 2016-07-05 2021-04-28 Dic株式会社 液晶化合物
CN116903706B (zh) * 2023-06-13 2024-05-17 深圳市祥根生物有限公司 一种棘白菌素类药物及其制备方法和用途

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE886575A (fr) * 1979-12-13 1981-06-10 Lilly Co Eli Derives de noyaux peptidiques cycliques, leur preparation et leur utilisation comme agents antifongiques
BE886576A (fr) * 1979-12-13 1981-06-10 Lilly Co Eli Derives de noyaux peptidiques cycliques, leur preparation et leur utilisation comme agents antifongiques
CA2037957A1 (en) * 1990-03-12 1991-09-13 Merck & Co., Inc. N-acylated cyclohexapeptide compounds
GB2241956A (en) 1990-03-16 1991-09-18 Merck & Co Inc N-acylated cyclohexapeptide compounds
US5330973A (en) * 1990-03-19 1994-07-19 Merck & Co., Inc. Lipopeptide derivatives
IL97347A0 (en) * 1990-03-19 1992-05-25 Merck & Co Inc Lipopeptide derivatives and antimicrobial compositions containing them
US5310726A (en) * 1990-03-19 1994-05-10 Merck & Co., Inc. Lipopeptide compounds
CZ288974B6 (cs) * 1992-03-19 2001-10-17 Eli Lilly And Company Acylový derivát echinocandinu, způsob jeho přípravy, farmaceutický prostředek s jeho obsahem a jeho pouľití

Also Published As

Publication number Publication date
JPH0656892A (ja) 1994-03-01
NL300334I2 (nl) 2008-05-01
JP3520071B2 (ja) 2004-04-19
NO930948D0 (no) 1993-03-16
JP2002226500A (ja) 2002-08-14
ES2174843T3 (es) 2002-11-16
IL105048A0 (en) 1993-07-08
HU9300785D0 (en) 1993-06-28
JP2004115540A (ja) 2004-04-15
DE122008000006I2 (de) 2011-07-21
CZ288974B6 (cs) 2001-10-17
JP3519754B2 (ja) 2004-04-19
HU211562A9 (en) 1995-12-28
NO930948L (no) 1993-09-20
KR100256036B1 (ko) 2000-05-01
PT561639E (pt) 2002-10-31
YU18593A (sh) 1996-10-09
IL122315A0 (en) 1998-04-05
RU2129562C1 (ru) 1999-04-27
CN1036715C (zh) 1997-12-17
IL122315A (en) 2002-03-10
DE122008000006I1 (de) 2008-04-17
DK0561639T3 (da) 2002-06-17
MX9301457A (es) 1994-02-28
TW264477B (forum.php) 1995-12-01
NZ512085A (en) 2003-08-29
AU6552996A (en) 1996-12-05
FI931202L (fi) 1993-09-20
FI931202A0 (fi) 1993-03-18
AU689391B2 (en) 1998-03-26
FI118768B (fi) 2008-03-14
HUT63637A (en) 1993-09-28
LU91406I2 (fr) 2008-03-10
YU49108B (sh) 2004-03-12
CA2091663A1 (en) 1993-09-20
KR930019694A (ko) 1993-10-18
CZ41693A3 (en) 1994-07-13
IL105048A (en) 2001-06-14
BR9301232A (pt) 1993-09-21
CN1080926A (zh) 1994-01-19
EP0561639A1 (en) 1993-09-22
AU3534193A (en) 1993-09-23
EP0561639B1 (en) 2002-05-15
NL300334I1 (nl) 2008-03-03
NZ299314A (en) 2001-09-28
HU225783B1 (en) 2007-09-28
ATE217635T1 (de) 2002-06-15
DE69331922D1 (de) 2002-06-20
CA2091663C (en) 2007-10-30
NZ247149A (en) 1996-10-28
DE69331922T2 (de) 2002-08-29

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