MX9702531A - Compuesto nuevo. - Google Patents

Compuesto nuevo.

Info

Publication number
MX9702531A
MX9702531A MX9702531A MX9702531A MX9702531A MX 9702531 A MX9702531 A MX 9702531A MX 9702531 A MX9702531 A MX 9702531A MX 9702531 A MX9702531 A MX 9702531A MX 9702531 A MX9702531 A MX 9702531A
Authority
MX
Mexico
Prior art keywords
antibiotic activity
pneumocystis carinii
cyclic hexapeptides
activities
prophylactic
Prior art date
Application number
MX9702531A
Other languages
English (en)
Inventor
Hidenori Ohki
Masaki Tomishima
Akira Yamada
Hisashi Takasugi
Original Assignee
Fujisawa Pharmaceutical Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26305774&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MX9702531(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from GB9420425A external-priority patent/GB9420425D0/en
Priority claimed from GBGB9508745.8A external-priority patent/GB9508745D0/en
Application filed by Fujisawa Pharmaceutical Co filed Critical Fujisawa Pharmaceutical Co
Publication of MX9702531A publication Critical patent/MX9702531A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/50—Cyclic peptides containing at least one abnormal peptide link
    • C07K7/54—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring
    • C07K7/56—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring the cyclisation not occurring through 2,4-diamino-butanoic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

Esta invencion se relaciona con compuestos químicos polipeptídicos nuevos representados por la siguiente formula (I): en la que R1 es como se definio en la descripcion y una sal del mismo farmaceuticamente aceptable, la cual tiene actividades antimicrobianas (especialmente, actividades antifungicas), actividad inhibidora en la beta-1, 3-glucano sintetasa, con procesos de preparacion del mismo, para una composicion farmacéutica que comprende la misma y para un método para el tratamiento profiláctico y/o terapéutico de enfermedades infecciosas incluyendo la infeccion Pneumocystis carinii (por ejemplo, neumonía Pneumocystis carinii) en un ser humano o en un animal.
MX9702531A 1994-10-07 1995-09-29 Compuesto nuevo. MX9702531A (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB9420425A GB9420425D0 (en) 1994-10-07 1994-10-07 New compound
GBGB9508745.8A GB9508745D0 (en) 1995-04-28 1995-04-28 New compound
PCT/JP1995/001983 WO1996011210A1 (en) 1994-10-07 1995-09-29 Cyclic hexapeptides having antibiotic activity

Publications (1)

Publication Number Publication Date
MX9702531A true MX9702531A (es) 1997-06-28

Family

ID=26305774

Family Applications (1)

Application Number Title Priority Date Filing Date
MX9702531A MX9702531A (es) 1994-10-07 1995-09-29 Compuesto nuevo.

Country Status (27)

Country Link
US (2) US6107458A (es)
EP (1) EP0788511B1 (es)
JP (2) JP2897427B2 (es)
KR (1) KR100353303B1 (es)
CN (1) CN1203089C (es)
AR (1) AR041770A1 (es)
AT (1) ATE229541T1 (es)
AU (1) AU696949B2 (es)
BR (2) BRPI9504791B8 (es)
CA (1) CA2202058C (es)
DE (2) DE69529172T2 (es)
DK (1) DK0788511T3 (es)
ES (1) ES2187575T3 (es)
FI (1) FI119988B (es)
FR (1) FR08C0028I2 (es)
HK (1) HK1004136A1 (es)
HU (1) HU228151B1 (es)
IL (1) IL115484A (es)
LU (1) LU91452I2 (es)
MX (1) MX9702531A (es)
NL (1) NL300352I2 (es)
NO (2) NO328483B1 (es)
OA (1) OA10475A (es)
PT (1) PT788511E (es)
RU (1) RU2165423C2 (es)
TR (1) TR199501229A2 (es)
WO (1) WO1996011210A1 (es)

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US5696084A (en) * 1996-08-16 1997-12-09 Abbott Laboratories Amino-lipopetide antifungal agents
AUPO371596A0 (en) * 1996-11-19 1996-12-12 Fujisawa Pharmaceutical Co., Ltd. New compound
AUPO381496A0 (en) * 1996-11-25 1996-12-19 Fujisawa Pharmaceutical Co., Ltd. New compound
WO1998057923A1 (fr) * 1997-06-18 1998-12-23 Fujisawa Pharmaceutical Co., Ltd. Nouveau procede de preparation
AU756792B2 (en) * 1998-02-09 2003-01-23 Fujisawa Pharmaceutical Co., Ltd. New compound
TR200003064T2 (tr) * 1998-02-09 2001-02-21 Fujisawa Pharmaceutical Co; Ltd. Yeni bileşik
US7084279B1 (en) * 1999-02-11 2006-08-01 Emisphere Technologies Inc. Oxadiazole compounds and compositions for delivering active agents
JP4854855B2 (ja) * 1999-02-11 2012-01-18 エミスフェアー・テクノロジーズ・インク オキサジアゾール化合物及び活性剤をデリバリーするための組成物
AUPP999799A0 (en) 1999-04-27 1999-05-20 Fujisawa Pharmaceutical Co., Ltd. New compound
AUPQ066399A0 (en) 1999-05-31 1999-06-24 Fujisawa Pharmaceutical Co., Ltd. Antifungal combination use
TWI233805B (en) * 1999-07-01 2005-06-11 Fujisawa Pharmaceutical Co Stabilized pharmaceutical composition in lyophilized form as antifungal agent
AU6564000A (en) 1999-07-27 2001-02-13 Aventis Pharma Deutschland Gmbh Novel cyclohexapeptide compounds, processes for their production and their use as a pharmaceutical
AUPQ462399A0 (en) * 1999-12-13 2000-01-13 Fujisawa Pharmaceutical Co., Ltd. New use
TWI250992B (en) * 2000-02-21 2006-03-11 Astellas Pharma Inc Polypeptide compounds for the prophylactic and/or therapeutic treatment of infectious diseases caused by pathogenic microorganisms
ES2191516B1 (es) * 2000-07-28 2005-01-01 Consejo Superior De Investigaciones Cientificas Antibioticos antifungicos de naturaleza peptidica inhibidores de la germinacion y el crecimiento de hongos fitopatogenos.
AUPQ938700A0 (en) * 2000-08-14 2000-09-07 Fujisawa Pharmaceutical Co., Ltd. Antifungal combination use
WO2002060446A1 (en) 2001-01-29 2002-08-08 Shionogi & Co., Ltd. Medicinal preparation containing 5-methyl-1-phenyl-2-(1h)-pyridone as active ingredient
JP2005053782A (ja) * 2001-08-31 2005-03-03 Fujisawa Pharmaceut Co Ltd 環状リポペプチド化合物の新規結晶
JP4625637B2 (ja) 2002-02-22 2011-02-02 シャイア エルエルシー 活性物質送達系及び活性物質を保護し投与する方法
WO2004014879A1 (en) * 2002-08-08 2004-02-19 Fujisawa Pharmaceutical Co., Ltd. New process
AU2003903205A0 (en) * 2003-06-23 2003-07-10 Fujisawa Pharmaceutical Co., Ltd. New compound
ATE381957T1 (de) 2003-07-22 2008-01-15 Theravance Inc Verwendung eines antimykotischen echinocandin- mittels in kombination mit einem antibakteriellen glycopeptid-mittel
CN1845751A (zh) * 2003-09-05 2006-10-11 默克公司 固定相和利用该固定相的纯化方法
EP1669350B1 (en) * 2003-09-22 2012-02-29 Msd K.K. Piperidine derivatives
US7476673B2 (en) * 2003-12-30 2009-01-13 Allergan, Inc. Disubstituted chalcone oximes as selective agonists of RARγ retinoid receptors
US20050261365A1 (en) * 2004-05-20 2005-11-24 The Scripps Research Institute Transthyretin stabilization
CN101084212A (zh) 2004-09-20 2007-12-05 泽农医药公司 杂环衍生物及其作为硬脂酰CoA去饱和酶介导剂的用途
AU2005286846A1 (en) 2004-09-20 2006-03-30 Xenon Pharmaceuticals Inc. Heterocyclic derivatives and their use as therapeutic agents
AR051092A1 (es) 2004-09-20 2006-12-20 Xenon Pharmaceuticals Inc Derivados heterociclicos y su uso como inhibidores de la estearoil-coa
WO2006034315A2 (en) 2004-09-20 2006-03-30 Xenon Pharmaceuticals Inc. Heterocyclic derivatives for the treatment of diseases mediated by stearoyl-coa desaturase enzymes
EP2269610A3 (en) 2004-09-20 2011-03-09 Xenon Pharmaceuticals Inc. Heterocyclic derivatives and their use as stearoyl-coa desaturase inhibitors
MX2007003319A (es) 2004-09-20 2007-06-05 Xenon Pharmaceuticals Inc Derivados heterociclicos y su uso como agentes terapeuticos.
AR051202A1 (es) 2004-09-20 2006-12-27 Xenon Pharmaceuticals Inc Derivados heterociclicos y su uso como inhibidores de la estearoil-coa desaturasa
WO2006044682A1 (en) * 2004-10-13 2006-04-27 Ptc Therapeutics, Inc. Compounds for nonsense suppression, and methods for their use
US8541457B2 (en) 2005-06-03 2013-09-24 Xenon Pharmaceuticals Inc. Aminothiazole derivatives as human stearoyl-CoA desaturase inhibitors
JP5222561B2 (ja) * 2005-10-07 2013-06-26 キッセイ薬品工業株式会社 含窒素芳香族複素環化合物およびそれを含有する医薬組成物
CN101516387B (zh) * 2006-07-26 2014-06-04 桑多斯股份公司 卡泊芬净制剂
US8853392B2 (en) 2007-06-03 2014-10-07 Vanderbilt University Benzamide mGluR5 positive allosteric modulators and methods of making and using same
ES2542849T3 (es) 2007-08-13 2015-08-12 Monsanto Technology Llc Composiciones y procedimientos de control de nematodos
WO2009057568A1 (ja) * 2007-10-29 2009-05-07 Astellas Pharma Inc. ポリペプチド化合物
US8034806B2 (en) 2007-11-02 2011-10-11 Vanderbilt University Bicyclic mGluR5 positive allosteric modulators and methods of making and using same
EA019001B1 (ru) * 2008-06-24 2013-12-30 Айрм Ллк Соединения и способы модулирования рецепторов, связанных с белком g
US9394340B2 (en) 2009-03-24 2016-07-19 Cadila Healthcare Limited Purification process for lipopeptides
BR112013023531A2 (pt) 2011-04-04 2016-12-06 Xellia Pharmaceuticals Aps processo de um único vaso para a fabricação de micafungina ou de um sal desta
BR112013026420A2 (pt) 2011-04-20 2020-11-03 Xellia Pharmaceuticals Aps método de produção de um sal de micafungina farmaceuticamente aceitável
CN102775476B (zh) * 2011-05-12 2015-01-07 上海天伟生物制药有限公司 一种米卡芬净钠盐的制备方法
EP2709609B1 (en) 2011-05-17 2017-10-04 Shionogi & Co., Ltd. Heterocyclic compounds
US20140329989A1 (en) * 2011-09-09 2014-11-06 Sandoz Ag Preparation of micafungin intermediates
CN102659930B (zh) 2012-03-30 2014-04-23 上海天伟生物制药有限公司 一种高纯度环肽类物质的晶体及其制备方法和用途
CN102627689B (zh) * 2012-03-30 2014-08-06 上海天伟生物制药有限公司 一种环肽类化合物的水合物及其制备方法和用途
CN102627688B (zh) 2012-03-30 2014-12-31 上海天伟生物制药有限公司 一种高纯度环肽化合物及其制备方法和用途
CN104861044B (zh) * 2014-05-29 2019-03-01 上海天伟生物制药有限公司 一种环肽类化合物的溶剂合物及其制备方法和用途
WO2016056023A2 (en) * 2014-10-07 2016-04-14 Alaparthi Lakshmi Prasad Intermediates and processes to prepare micafungin
CA2937365C (en) 2016-03-29 2018-09-18 F. Hoffmann-La Roche Ag Granulate formulation of 5-methyl-1-phenyl-2-(1h)-pyridone and method of making the same
EP3485873A1 (en) 2017-11-17 2019-05-22 Cadila Healthcare Limited Stable pharmaceutical injectable compositions of micafungin
CN113087775B (zh) * 2018-05-31 2022-07-08 杭州中美华东制药有限公司 米卡芬净钠新晶型ii及其制备方法
WO2020013116A1 (ja) * 2018-07-10 2020-01-16 京都薬品工業株式会社 Ｐｔｐ－１ｂ阻害剤およびその用途
CN110734408A (zh) * 2019-10-22 2020-01-31 重庆康乐制药有限公司 一种米卡芬净类衍生物侧链中间体的制备方法

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IL98506A (en) * 1990-06-18 1996-09-12 Fujisawa Pharmaceutical Co Peptides, of antibiotics, processes for their preparation and pharmaceutical preparations containing them
IL122315A (en) * 1992-03-19 2002-03-10 Lilly Co Eli Cyclic peptides and antifungal pharmaceutical compositions containing them

Also Published As

Publication number Publication date
AU3578095A (en) 1996-05-02
JPH10507174A (ja) 1998-07-14
ES2187575T3 (es) 2003-06-16
JP3518665B2 (ja) 2004-04-12
FI971397A (fi) 1997-05-27
NO2010016I2 (no) 2011-10-17
AR041770A1 (es) 2005-06-01
IL115484A (en) 2000-07-16
NL300352I2 (nl) 2008-11-03
OA10475A (en) 2002-04-08
DE69529172T2 (de) 2003-04-17
DE122008000025I1 (de) 2008-08-21
KR100353303B1 (ko) 2003-01-15
LU91452I2 (fr) 2008-08-04
NO971544L (no) 1997-06-04
KR970707150A (ko) 1997-12-01
BR9504791B1 (pt) 2010-10-05
NL300352I1 (nl) 2008-08-01
PT788511E (pt) 2003-04-30
NO971544D0 (no) 1997-04-04
DK0788511T3 (da) 2003-03-31
WO1996011210A1 (en) 1996-04-18
TR199501229A2 (tr) 1996-07-21
HU228151B1 (en) 2012-12-28
DE69529172D1 (de) 2003-01-23
ATE229541T1 (de) 2002-12-15
US6265536B1 (en) 2001-07-24
CN1203089C (zh) 2005-05-25
HK1004136A1 (en) 1998-11-20
FI971397A0 (fi) 1997-04-04
DE122008000025I2 (de) 2011-02-17
CA2202058A1 (en) 1996-04-18
US6107458A (en) 2000-08-22
IL115484A0 (en) 1996-01-19
HUT77736A (hu) 1998-07-28
CA2202058C (en) 2007-11-06
FR08C0028I2 (es) 2009-11-20
BR9504791A (pt) 1996-10-22
FR08C0028I1 (es) 2008-08-15
AU696949B2 (en) 1998-09-24
EP0788511B1 (en) 2002-12-11
JPH10324695A (ja) 1998-12-08
NO2010016I1 (no) 2010-08-16
JP2897427B2 (ja) 1999-05-31
CN1168675A (zh) 1997-12-24
BRPI9504791B8 (pt) 2019-12-31
RU2165423C2 (ru) 2001-04-20
FI119988B (fi) 2009-05-29
NO328483B1 (no) 2010-03-01
EP0788511A1 (en) 1997-08-13

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