DE122008000025I1 - Zyklische hexapeptide mit antibiotischer aktivität - Google Patents

Zyklische hexapeptide mit antibiotischer aktivität

Info

Publication number
DE122008000025I1
DE122008000025I1 DE122008000025C DE122008000025C DE122008000025I1 DE 122008000025 I1 DE122008000025 I1 DE 122008000025I1 DE 122008000025 C DE122008000025 C DE 122008000025C DE 122008000025 C DE122008000025 C DE 122008000025C DE 122008000025 I1 DE122008000025 I1 DE 122008000025I1
Authority
DE
Germany
Prior art keywords
antibiotic activity
cyclic hexapeptides
hexapeptides
cyclic
antibiotic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
DE122008000025C
Other languages
English (en)
Other versions
DE122008000025I2 (de
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Astellas Pharma Inc
Original Assignee
Astellas Pharma Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26305774&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE122008000025(I1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from GB9420425A external-priority patent/GB9420425D0/en
Priority claimed from GBGB9508745.8A external-priority patent/GB9508745D0/en
Application filed by Astellas Pharma Inc filed Critical Astellas Pharma Inc
Publication of DE122008000025I1 publication Critical patent/DE122008000025I1/de
Publication of DE122008000025I2 publication Critical patent/DE122008000025I2/de
Active legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/50—Cyclic peptides containing at least one abnormal peptide link
    • C07K7/54—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring
    • C07K7/56—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring the cyclisation not occurring through 2,4-diamino-butanoic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
DE122008000025C 1994-10-07 1995-09-29 Zyklische hexapeptide mit antibiotischer aktivität Active DE122008000025I2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB9420425A GB9420425D0 (en) 1994-10-07 1994-10-07 New compound
GBGB9508745.8A GB9508745D0 (en) 1995-04-28 1995-04-28 New compound
PCT/JP1995/001983 WO1996011210A1 (en) 1994-10-07 1995-09-29 Cyclic hexapeptides having antibiotic activity

Publications (2)

Publication Number Publication Date
DE122008000025I1 true DE122008000025I1 (de) 2008-08-21
DE122008000025I2 DE122008000025I2 (de) 2011-02-17

Family

ID=26305774

Family Applications (2)

Application Number Title Priority Date Filing Date
DE122008000025C Active DE122008000025I2 (de) 1994-10-07 1995-09-29 Zyklische hexapeptide mit antibiotischer aktivität
DE69529172T Expired - Lifetime DE69529172T2 (de) 1994-10-07 1995-09-29 Zyklische hexapeptide mit antibiotischer aktivität

Family Applications After (1)

Application Number Title Priority Date Filing Date
DE69529172T Expired - Lifetime DE69529172T2 (de) 1994-10-07 1995-09-29 Zyklische hexapeptide mit antibiotischer aktivität

Country Status (27)

Country Link
US (2) US6107458A (de)
EP (1) EP0788511B1 (de)
JP (2) JP2897427B2 (de)
KR (1) KR100353303B1 (de)
CN (1) CN1203089C (de)
AR (1) AR041770A1 (de)
AT (1) ATE229541T1 (de)
AU (1) AU696949B2 (de)
BR (2) BRPI9504791B8 (de)
CA (1) CA2202058C (de)
DE (2) DE122008000025I2 (de)
DK (1) DK0788511T3 (de)
ES (1) ES2187575T3 (de)
FI (1) FI119988B (de)
FR (1) FR08C0028I2 (de)
HK (1) HK1004136A1 (de)
HU (1) HU228151B1 (de)
IL (1) IL115484A (de)
LU (1) LU91452I2 (de)
MX (1) MX9702531A (de)
NL (1) NL300352I2 (de)
NO (2) NO328483B1 (de)
OA (1) OA10475A (de)
PT (1) PT788511E (de)
RU (1) RU2165423C2 (de)
TR (1) TR199501229A2 (de)
WO (1) WO1996011210A1 (de)

Families Citing this family (58)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5696084A (en) * 1996-08-16 1997-12-09 Abbott Laboratories Amino-lipopetide antifungal agents
AUPO371596A0 (en) * 1996-11-19 1996-12-12 Fujisawa Pharmaceutical Co., Ltd. New compound
AUPO381496A0 (en) * 1996-11-25 1996-12-19 Fujisawa Pharmaceutical Co., Ltd. New compound
WO1998057923A1 (fr) * 1997-06-18 1998-12-23 Fujisawa Pharmaceutical Co., Ltd. Nouveau procede de preparation
AU756792B2 (en) * 1998-02-09 2003-01-23 Fujisawa Pharmaceutical Co., Ltd. New compound
US6232290B1 (en) * 1998-02-09 2001-05-15 Fujisawa Pharmaceutical Co., Ltd. Cyclic hexapeptides with antimicrobial activity
CA2360220C (en) * 1999-02-11 2009-09-08 Emisphere Technologies, Inc. Oxadiazole compounds and compositions for delivering active agents
US7084279B1 (en) * 1999-02-11 2006-08-01 Emisphere Technologies Inc. Oxadiazole compounds and compositions for delivering active agents
AUPP999799A0 (en) * 1999-04-27 1999-05-20 Fujisawa Pharmaceutical Co., Ltd. New compound
AUPQ066399A0 (en) * 1999-05-31 1999-06-24 Fujisawa Pharmaceutical Co., Ltd. Antifungal combination use
TWI233805B (en) * 1999-07-01 2005-06-11 Fujisawa Pharmaceutical Co Stabilized pharmaceutical composition in lyophilized form as antifungal agent
DE60040989D1 (de) 1999-07-27 2009-01-15 Aventis Pharma Gmbh Cyclohexapeptide, deren herstellung und verwendung in pharmazeutische zusammensetzungen
AUPQ462399A0 (en) * 1999-12-13 2000-01-13 Fujisawa Pharmaceutical Co., Ltd. New use
TWI250992B (en) * 2000-02-21 2006-03-11 Astellas Pharma Inc Polypeptide compounds for the prophylactic and/or therapeutic treatment of infectious diseases caused by pathogenic microorganisms
ES2191516B1 (es) * 2000-07-28 2005-01-01 Consejo Superior De Investigaciones Cientificas Antibioticos antifungicos de naturaleza peptidica inhibidores de la germinacion y el crecimiento de hongos fitopatogenos.
AUPQ938700A0 (en) * 2000-08-14 2000-09-07 Fujisawa Pharmaceutical Co., Ltd. Antifungal combination use
ATE452637T1 (de) 2001-01-29 2010-01-15 Shionogi & Co Arzneipräparat, das als wirkstoff 5-methyl-1- phenyl-2-(1h)-pyridon enthält
JP2005053782A (ja) * 2001-08-31 2005-03-03 Fujisawa Pharmaceut Co Ltd 環状リポペプチド化合物の新規結晶
IL163666A0 (en) 2002-02-22 2005-12-18 New River Pharmaceuticals Inc Active agent delivery systems and methods for protecting and administering active agents
JP4784093B2 (ja) * 2002-08-08 2011-09-28 アステラス製薬株式会社 イソオキサゾリル安息香酸の製造法
AU2003903205A0 (en) * 2003-06-23 2003-07-10 Fujisawa Pharmaceutical Co., Ltd. New compound
EP1654036B1 (de) 2003-07-22 2007-12-26 Theravance, Inc. Verwendung eines antimykotischen echinocandin-mittels in kombination mit einem antibakteriellen glycopeptid-mittel
CA2537574A1 (en) * 2003-09-05 2005-03-24 Merck & Co., Inc. Stationary phases and a purification process using the stationary phases
CN1902177A (zh) * 2003-09-22 2007-01-24 万有制药株式会社 新哌啶衍生物
US7476673B2 (en) * 2003-12-30 2009-01-13 Allergan, Inc. Disubstituted chalcone oximes as selective agonists of RARγ retinoid receptors
CN101198598A (zh) * 2004-05-20 2008-06-11 弗尔德里克斯制药股份有限公司 2-((杂)芳基)-苯并噁唑化合物及其衍生物、组合物以及用于稳定和抑制甲状腺素转运蛋白错重叠的方法
EP1804799B1 (de) 2004-09-20 2013-08-21 Xenon Pharmaceuticals Inc. Heterozyklische Derivate und ihre Verwendung als Stearoyl-Coa-Desaturase-Inhibitoren
MX2007003332A (es) 2004-09-20 2007-06-05 Xenon Pharmaceuticals Inc Derivados heterociclicos y su uso como inhibidores de estearoil-coa-desaturasa.
BRPI0515483A (pt) 2004-09-20 2008-07-22 Xenon Pharmaceuticals Inc derivados heterocìclicos para o tratamento de doenças mediadas por enzimas estearoil-coa desaturase
JP5043668B2 (ja) 2004-09-20 2012-10-10 ゼノン・ファーマシューティカルズ・インコーポレイテッド 複素環誘導体および治療薬としてのそれらの使用
JP5149009B2 (ja) 2004-09-20 2013-02-20 ゼノン・ファーマシューティカルズ・インコーポレイテッド ヒトステアロイル−ＣｏＡデサチュラーゼを阻害するためのピリダジン誘導体
TW200626154A (en) 2004-09-20 2006-08-01 Xenon Pharmaceuticals Inc Heterocyclic derivatives and their use as therapeutic agents
MX2007003327A (es) 2004-09-20 2007-06-05 Xenon Pharmaceuticals Inc Derivados heterociclicos, y su uso como mediadores de estearoil-coa desaturasa.
CA2583177A1 (en) * 2004-10-13 2006-04-27 Ptc Therapeutics, Inc. Compounds for nonsense suppression, and methods for their use
MX2007015216A (es) 2005-06-03 2008-02-22 Xenon Pharmaceuticals Inc Derivados de aminotiazol y sus usos como agentes terapeuticos.
CN101282936B (zh) * 2005-10-07 2012-05-16 橘生药品工业株式会社 氮化杂环化合物及包含其的药物组合物
CN101516387B (zh) * 2006-07-26 2014-06-04 桑多斯股份公司 卡泊芬净制剂
US8853392B2 (en) 2007-06-03 2014-10-07 Vanderbilt University Benzamide mGluR5 positive allosteric modulators and methods of making and using same
HUE027022T2 (en) 2007-08-13 2016-08-29 Monsanto Technology Llc Preparations and procedures for controlling nematodes
KR20100075892A (ko) * 2007-10-29 2010-07-05 아스테라스 세이야쿠 가부시키가이샤 폴리펩티드 화합물
US8034806B2 (en) 2007-11-02 2011-10-11 Vanderbilt University Bicyclic mGluR5 positive allosteric modulators and methods of making and using same
AU2009271328B2 (en) * 2008-06-24 2012-09-06 Irm Llc Compounds and methods for modulating G protein-coupled receptors
US9394340B2 (en) 2009-03-24 2016-07-19 Cadila Healthcare Limited Purification process for lipopeptides
BR112013023531A2 (pt) 2011-04-04 2016-12-06 Xellia Pharmaceuticals Aps processo de um único vaso para a fabricação de micafungina ou de um sal desta
SI2699327T1 (sl) 2011-04-20 2015-11-30 Xelia Pharmaceuticals Aps Postopek čiščenja mikafungina
CN102775476B (zh) 2011-05-12 2015-01-07 上海天伟生物制药有限公司 一种米卡芬净钠盐的制备方法
EP2709609B1 (de) 2011-05-17 2017-10-04 Shionogi & Co., Ltd. Heterozyklische verbindungen
KR20140069097A (ko) * 2011-09-09 2014-06-09 산도즈 아게 미카펀진 중간체의 제조
CN102627689B (zh) * 2012-03-30 2014-08-06 上海天伟生物制药有限公司 一种环肽类化合物的水合物及其制备方法和用途
CN102627688B (zh) 2012-03-30 2014-12-31 上海天伟生物制药有限公司 一种高纯度环肽化合物及其制备方法和用途
CN102659930B (zh) * 2012-03-30 2014-04-23 上海天伟生物制药有限公司 一种高纯度环肽类物质的晶体及其制备方法和用途
EP3150623B1 (de) * 2014-05-29 2019-04-03 Shanghai Techwell Biopharmaceutical Co., Ltd Solvat einer cyclischen peptidverbindung, herstellungsverfahren und verwendungen davon
EP3226885A4 (de) * 2014-10-07 2018-07-18 Alaparthi, Lakshmi Prasad Zwischenprodukte und verfahren zur herstellung von micafungin
CA2937365C (en) 2016-03-29 2018-09-18 F. Hoffmann-La Roche Ag Granulate formulation of 5-methyl-1-phenyl-2-(1h)-pyridone and method of making the same
EP3485873A1 (de) 2017-11-17 2019-05-22 Cadila Healthcare Limited Stabile pharmazeutische injizierbare zusammensetzungen von micafungin
CN108752430B (zh) * 2018-05-31 2022-02-18 杭州中美华东制药有限公司 米卡芬净钠新晶型及其制备方法
WO2020013116A1 (ja) * 2018-07-10 2020-01-16 京都薬品工業株式会社 Ｐｔｐ－１ｂ阻害剤およびその用途
CN110734408A (zh) * 2019-10-22 2020-01-31 重庆康乐制药有限公司 一种米卡芬净类衍生物侧链中间体的制备方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI912873A (fi) * 1990-06-18 1991-12-19 Fujisawa Pharmaceutical Co Ny polypeptidfoerening och foerfarande foer dess framstaellning.
CZ288974B6 (cs) * 1992-03-19 2001-10-17 Eli Lilly And Company Acylový derivát echinocandinu, způsob jeho přípravy, farmaceutický prostředek s jeho obsahem a jeho pouľití

Also Published As

Publication number Publication date
CA2202058A1 (en) 1996-04-18
ES2187575T3 (es) 2003-06-16
MX9702531A (es) 1997-06-28
BR9504791A (pt) 1996-10-22
TR199501229A2 (tr) 1996-07-21
LU91452I2 (fr) 2008-08-04
HUT77736A (hu) 1998-07-28
NO971544L (no) 1997-06-04
PT788511E (pt) 2003-04-30
BR9504791B1 (pt) 2010-10-05
EP0788511B1 (de) 2002-12-11
DK0788511T3 (da) 2003-03-31
KR100353303B1 (ko) 2003-01-15
JPH10507174A (ja) 1998-07-14
DE69529172T2 (de) 2003-04-17
IL115484A0 (en) 1996-01-19
JP3518665B2 (ja) 2004-04-12
DE122008000025I2 (de) 2011-02-17
NL300352I1 (nl) 2008-08-01
BRPI9504791B8 (pt) 2019-12-31
JPH10324695A (ja) 1998-12-08
NO971544D0 (no) 1997-04-04
NO328483B1 (no) 2010-03-01
FR08C0028I2 (de) 2009-11-20
OA10475A (en) 2002-04-08
ATE229541T1 (de) 2002-12-15
JP2897427B2 (ja) 1999-05-31
AR041770A1 (es) 2005-06-01
CN1203089C (zh) 2005-05-25
US6107458A (en) 2000-08-22
WO1996011210A1 (en) 1996-04-18
EP0788511A1 (de) 1997-08-13
FI971397A0 (fi) 1997-04-04
US6265536B1 (en) 2001-07-24
NO2010016I2 (no) 2011-10-17
IL115484A (en) 2000-07-16
HU228151B1 (en) 2012-12-28
NL300352I2 (nl) 2008-11-03
CN1168675A (zh) 1997-12-24
FR08C0028I1 (de) 2008-08-15
DE69529172D1 (de) 2003-01-23
RU2165423C2 (ru) 2001-04-20
KR970707150A (ko) 1997-12-01
HK1004136A1 (en) 1998-11-20
NO2010016I1 (no) 2010-08-16
FI971397A (fi) 1997-05-27
AU696949B2 (en) 1998-09-24
FI119988B (fi) 2009-05-29
CA2202058C (en) 2007-11-06
AU3578095A (en) 1996-05-02

Similar Documents

Publication Publication Date Title
DE69529172D1 (de) Zyklische hexapeptide mit antibiotischer aktivität
DE69624966D1 (de) Zyklische Hexapeptide mit fungizider Aktivität
BR9708149A (pt) Imidazois substituídos com cicloalquila
FI952931A0 (fi) Insuliinianalogiformulaatioita
DE69701847D1 (de) Copolyester-Elastomer
ATA101795A (de) Insulinanalogon-protamin-komplex
DE69535257D1 (de) Verbundmaterial mit kontrollierter Elastizität
DE69629075D1 (de) Zyklische Peptide mit fungizider Wirkung
EE9700087A (et) Uued immunomodulatoorse toimega peptiidid
DE69624167D1 (de) Zyklische Peptide mit fungizider Wirkung
FI970168A0 (fi) Peptidejä
ID16496A (id) Benang karet
DK0856007T3 (da) cyclopeptidderivater
EE9600208A (et) Uued immuunomodulatoorse toimega peptiidid
EP0500170A3 (en) Cyclic hexapeptides having antibiotic activity
DE69533337D1 (de) Bakterielles protein mit xylanase aktivität
NO982280L (no) Cyklopeptider
NO934805D0 (no) Manifoldanordning
FI960119A (fi) Peptidit, joilla on oksitosiinin vastaista aktiivisuutta
EP0859007A4 (de) Zyklische hexapeptide
KR940002677U (ko) 공기 주입식 때밀이구
KR950008212U (ko) 흡착기능을 겸한 공기주입기
ITMI922963A1 (it) Peptidi ciclici
KR950009221U (ko) 자동차의 스로틀 보디 고정구조
IT234093Y1 (it) Sedia con scocca