DE60040989D1 - Cyclohexapeptide, deren herstellung und verwendung in pharmazeutische zusammensetzungen - Google Patents

Cyclohexapeptide, deren herstellung und verwendung in pharmazeutische zusammensetzungen

Info

Publication number
DE60040989D1
DE60040989D1 DE60040989T DE60040989T DE60040989D1 DE 60040989 D1 DE60040989 D1 DE 60040989D1 DE 60040989 T DE60040989 T DE 60040989T DE 60040989 T DE60040989 T DE 60040989T DE 60040989 D1 DE60040989 D1 DE 60040989D1
Authority
DE
Germany
Prior art keywords
sub
aryl
substituted
alkyl
independently
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE60040989T
Other languages
English (en)
Inventor
Lal Bansi
Genbhau Gund Vitthal
Kumar Gangopadhyay Ashok
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanofi Aventis Deutschland GmbH
Original Assignee
Aventis Pharma Deutschland GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aventis Pharma Deutschland GmbH filed Critical Aventis Pharma Deutschland GmbH
Application granted granted Critical
Publication of DE60040989D1 publication Critical patent/DE60040989D1/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/50—Cyclic peptides containing at least one abnormal peptide link
    • C07K7/54—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring
    • C07K7/56—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring the cyclisation not occurring through 2,4-diamino-butanoic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Communicable Diseases (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
DE60040989T 1999-07-27 2000-07-15 Cyclohexapeptide, deren herstellung und verwendung in pharmazeutische zusammensetzungen Expired - Fee Related DE60040989D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP99114649 1999-07-27
PCT/EP2000/006769 WO2001007468A2 (en) 1999-07-27 2000-07-15 Novel cyclohexapeptide compounds, processes for their production and their use as a pharmaceutical

Publications (1)

Publication Number Publication Date
DE60040989D1 true DE60040989D1 (de) 2009-01-15

Family

ID=8238665

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60040989T Expired - Fee Related DE60040989D1 (de) 1999-07-27 2000-07-15 Cyclohexapeptide, deren herstellung und verwendung in pharmazeutische zusammensetzungen

Country Status (8)

Country Link
US (1) US7166572B1 (de)
EP (1) EP1204677B1 (de)
JP (1) JP2003505468A (de)
AT (1) ATE416189T1 (de)
AU (1) AU6564000A (de)
CA (1) CA2380176A1 (de)
DE (1) DE60040989D1 (de)
WO (1) WO2001007468A2 (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2833596B1 (fr) * 2001-12-14 2005-02-18 Aventis Pharma Sa Procede de preparation de derives d'echinocandine
US8048853B2 (en) * 2008-06-13 2011-11-01 Xellia Pharmaceuticals Aps Process for preparing pharmaceutical compound and intermediates thereof
EP2240507A2 (de) * 2008-06-25 2010-10-20 TEVA Gyógyszergyár Zártkörüen Müködö Részvénytársaság Verfahren zur herstellung von hochreinen azacyclohexapeptiden
US20090324635A1 (en) * 2008-06-25 2009-12-31 Ferenc Korodi Caspofungin free of caspofungin impurity A

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5914313A (en) 1991-10-17 1999-06-22 Merck & Co., Inc. 1- 4-hydroxy-5-aminoethyloxy-N2 -(10,12-dimethyl-1-oxotetradecyl)ornithine!-5-(3-hydroxyglutamine)-6-(3-hydroxyproline)echinocandin B, other aminoalkyl derivatives and salts thereof
EP0539088B1 (de) * 1991-10-17 1996-07-17 Merck & Co. Inc. Echinocandin-B-Derivat
US5378804A (en) * 1993-03-16 1995-01-03 Merck & Co., Inc. Aza cyclohexapeptide compounds
US5541160A (en) * 1994-04-04 1996-07-30 Merck & Co., Inc. Antifungal and anti-pneumocystis compounds, compositions containing such compounds, and methods of use
US6107458A (en) 1994-10-07 2000-08-22 Fujisawa Pharmaceutical Co., Ltd. Cyclic hexapeptides having antibiotic activity
CA2211138A1 (en) * 1995-01-26 1996-08-01 Merck & Co., Inc. Novel antifungal cyclohexapeptides

Also Published As

Publication number Publication date
AU6564000A (en) 2001-02-13
EP1204677B1 (de) 2008-12-03
CA2380176A1 (en) 2001-02-01
WO2001007468A3 (en) 2001-11-08
JP2003505468A (ja) 2003-02-12
US7166572B1 (en) 2007-01-23
EP1204677A2 (de) 2002-05-15
WO2001007468A2 (en) 2001-02-01
ATE416189T1 (de) 2008-12-15

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee