NO175097C - Analogifremgangsmåte for fremstilling av terapeutisk aktive hydrazoner - Google Patents

Analogifremgangsmåte for fremstilling av terapeutisk aktive hydrazoner

Info

Publication number
NO175097C
NO175097C NO911777A NO911777A NO175097C NO 175097 C NO175097 C NO 175097C NO 911777 A NO911777 A NO 911777A NO 911777 A NO911777 A NO 911777A NO 175097 C NO175097 C NO 175097C
Authority
NO
Norway
Prior art keywords
independently
hydrazones
preparation
hydrogen
therapeutically active
Prior art date
Application number
NO911777A
Other languages
English (en)
Other versions
NO911777D0 (no
NO175097B (no
NO911777L (no
Inventor
Jaroslav Stanek
Jorg Frei
Giorgio Caravatti
Original Assignee
Ciba Geigy Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy Ag filed Critical Ciba Geigy Ag
Publication of NO911777D0 publication Critical patent/NO911777D0/no
Publication of NO911777L publication Critical patent/NO911777L/no
Publication of NO175097B publication Critical patent/NO175097B/no
Publication of NO175097C publication Critical patent/NO175097C/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C337/00—Derivatives of thiocarbonic acids containing functional groups covered by groups C07C333/00 or C07C335/00 in which at least one nitrogen atom of these functional groups is further bound to another nitrogen atom not being part of a nitro or nitroso group
    • C07C337/06—Compounds containing any of the groups, e.g. thiosemicarbazides
    • C07C337/08—Compounds containing any of the groups, e.g. thiosemicarbazides the other nitrogen atom being further doubly-bound to a carbon atom, e.g. thiosemicarbazones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • A61P33/06—Antimalarials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C243/00—Compounds containing chains of nitrogen atoms singly-bound to each other, e.g. hydrazines, triazanes
    • C07C243/10—Hydrazines
    • C07C243/20—Hydrazines having nitrogen atoms of hydrazine groups bound to carbon atoms of rings other than six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C281/00—Derivatives of carbonic acid containing functional groups covered by groups C07C269/00 - C07C279/00 in which at least one nitrogen atom of these functional groups is further bound to another nitrogen atom not being part of a nitro or nitroso group
    • C07C281/06—Compounds containing any of the groups, e.g. semicarbazides
    • C07C281/08—Compounds containing any of the groups, e.g. semicarbazides the other nitrogen atom being further doubly-bound to a carbon atom, e.g. semicarbazones
    • C07C281/12—Compounds containing any of the groups, e.g. semicarbazides the other nitrogen atom being further doubly-bound to a carbon atom, e.g. semicarbazones the carbon atom being part of a ring other than a six-membered aromatic ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C281/00—Derivatives of carbonic acid containing functional groups covered by groups C07C269/00 - C07C279/00 in which at least one nitrogen atom of these functional groups is further bound to another nitrogen atom not being part of a nitro or nitroso group
    • C07C281/16—Compounds containing any of the groups, e.g. aminoguanidine
    • C07C281/18—Compounds containing any of the groups, e.g. aminoguanidine the other nitrogen atom being further doubly-bound to a carbon atom, e.g. guanylhydrazones
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2602/00—Systems containing two condensed rings
    • C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
    • C07C2602/04—One of the condensed rings being a six-membered aromatic ring
    • C07C2602/06—One of the condensed rings being a six-membered aromatic ring the other ring being four-membered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2602/00—Systems containing two condensed rings
    • C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
    • C07C2602/04—One of the condensed rings being a six-membered aromatic ring
    • C07C2602/08—One of the condensed rings being a six-membered aromatic ring the other ring being five-membered, e.g. indane

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Materials For Photolithography (AREA)
  • Wire Bonding (AREA)
  • Diaphragms For Electromechanical Transducers (AREA)
  • Ultra Sonic Daignosis Equipment (AREA)
  • Peptides Or Proteins (AREA)
  • Plural Heterocyclic Compounds (AREA)
NO911777A 1990-05-07 1991-05-06 Analogifremgangsmåte for fremstilling av terapeutisk aktive hydrazoner NO175097C (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH153890 1990-05-07

Publications (4)

Publication Number Publication Date
NO911777D0 NO911777D0 (no) 1991-05-06
NO911777L NO911777L (no) 1991-11-08
NO175097B NO175097B (no) 1994-05-24
NO175097C true NO175097C (no) 1994-08-31

Family

ID=4212764

Family Applications (1)

Application Number Title Priority Date Filing Date
NO911777A NO175097C (no) 1990-05-07 1991-05-06 Analogifremgangsmåte for fremstilling av terapeutisk aktive hydrazoner

Country Status (26)

Country Link
EP (1) EP0456133B1 (no)
JP (1) JP2565602B2 (no)
KR (1) KR100203234B1 (no)
AT (1) ATE119878T1 (no)
AU (1) AU645799B2 (no)
CA (1) CA2041832C (no)
CY (1) CY2080B1 (no)
CZ (1) CZ279340B6 (no)
DE (1) DE59104930D1 (no)
DK (1) DK0456133T3 (no)
ES (1) ES2069768T3 (no)
FI (1) FI107916B (no)
GR (1) GR3015574T3 (no)
HK (1) HK1000919A1 (no)
HU (1) HU218221B (no)
ID (1) ID1040B (no)
IE (1) IE66157B1 (no)
IL (1) IL98008A (no)
NO (1) NO175097C (no)
NZ (1) NZ238033A (no)
PT (1) PT97571B (no)
RU (2) RU2057748C1 (no)
SA (1) SA91120283B1 (no)
SK (1) SK279136B6 (no)
TW (1) TW202428B (no)
ZA (1) ZA913391B (no)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5395855A (en) * 1990-05-07 1995-03-07 Ciba-Geigy Corporation Hydrazones
RU2081108C1 (ru) * 1991-10-16 1997-06-10 Циба-Гейги АГ Аддитивные соли кислот с основанием и фармацевтическая композиция, обладающая противоопухолевой активностью
ATE133938T1 (de) * 1992-04-03 1996-02-15 Innothera Lab Sa Indan-1,3-dion und indan-1,2,3-trionderivate, verfahren zu ihrer herstellung und ihre therapeutische verwendung
ES2103166B1 (es) * 1992-08-26 1998-04-01 Ciba Geigy Ag Procedimiento para la obtencion de amidinohidrazonas biciclicas.
FR2710639B1 (fr) * 1993-10-01 1995-12-22 Innothera Lab Sa Dérivés d'indane cétoniques, leur procédé d'obtention, leur application thérapeutique.
ATE278676T1 (de) * 1995-01-26 2004-10-15 Novartis Pharma Gmbh Imdazol-derivate, deren herstellung und deren verwendung als s-adenosylmethionin decarboxylase (=samdc) inhibitoren
EP1408028A1 (en) * 2002-10-09 2004-04-14 Institut National De La Sante Et De La Recherche Medicale (Inserm) S-adenosyl methionine decarboxylase inhibition for the treatment of a herpes simplex virus infection
EP1834669A1 (en) * 2006-03-15 2007-09-19 Heinrich-Pette-Institut Use of specific hydrazone compounds for the treatment of viral infections
EP1884515A1 (en) * 2006-07-31 2008-02-06 Laboratorios del Dr. Esteve S.A. Substituted indanyl sulfonamide compounds, their preparation and use as medicaments
CN102627593A (zh) * 2012-02-23 2012-08-08 河南师范大学 具有抗癌活性的1，4-二羟基-2-甲酰基-9，10蒽醌缩氨硫脲新化合物及制备方法
AU2015282901B2 (en) * 2014-07-02 2019-01-17 Inflectis Bioscience O-alkyl-benzylideneguanidine derivatives and therapeutic use for the treatment of disorders associated an accumulation of misfolded proteins

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL7407469A (nl) * 1974-06-01 1975-12-03 Akzo Nv Nieuwe amidinohydrazonverbindingen.
DE3416695A1 (de) * 1984-05-05 1985-11-07 Bayer Ag, 5090 Leverkusen Amidinohydrazone von tetralin-, chromon-, thiochromon- und tretrahydrochinolin-derivaten, verfahren zu ihrer herstellung sowie ihre verwendung in arzneimitteln
EP0377304B1 (en) * 1988-12-27 1994-03-09 E.I. Du Pont De Nemours And Company Substituted semicarbazone arthropodicides

Also Published As

Publication number Publication date
IE66157B1 (en) 1995-12-13
HU218221B (hu) 2000-06-28
EP0456133A1 (de) 1991-11-13
SK279136B6 (sk) 1998-07-08
NO911777D0 (no) 1991-05-06
CA2041832C (en) 2002-09-17
CY2080B1 (en) 1998-10-16
TW202428B (no) 1993-03-21
ES2069768T3 (es) 1995-05-16
ID1040B (id) 1996-10-25
KR910019964A (ko) 1991-12-19
JP2565602B2 (ja) 1996-12-18
SA91120283B1 (ar) 2005-12-17
IL98008A0 (en) 1992-06-21
RU2057748C1 (ru) 1996-04-10
NO175097B (no) 1994-05-24
JPH04225946A (ja) 1992-08-14
IE911530A1 (en) 1991-11-20
HUT57183A (en) 1991-11-28
GR3015574T3 (en) 1995-06-30
DK0456133T3 (da) 1995-05-22
FI107916B (fi) 2001-10-31
ZA913391B (en) 1991-12-24
EP0456133B1 (de) 1995-03-15
CA2041832A1 (en) 1991-11-08
KR100203234B1 (ko) 1999-06-15
PT97571B (pt) 1999-04-30
CZ279340B6 (cs) 1995-04-12
ATE119878T1 (de) 1995-04-15
NZ238033A (en) 1993-01-27
AU645799B2 (en) 1994-01-27
PT97571A (pt) 1992-01-31
FI912164A (fi) 1991-11-08
AU7596791A (en) 1991-11-07
HK1000919A1 (en) 1998-05-08
NO911777L (no) 1991-11-08
FI912164A0 (fi) 1991-05-03
CS131791A3 (en) 1992-03-18
RU2066311C1 (ru) 1996-09-10
DE59104930D1 (de) 1995-04-20
IL98008A (en) 1996-08-04

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NO175097C (no) Analogifremgangsmåte for fremstilling av terapeutisk aktive hydrazoner
IT1250749B (it) Composti eterociclici ad attivita' a ii antagonista
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