FI912873A - Ny polypeptidfoerening och foerfarande foer dess framstaellning. - Google Patents

Ny polypeptidfoerening och foerfarande foer dess framstaellning. Download PDF

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Publication number
FI912873A
FI912873A FI912873A FI912873A FI912873A FI 912873 A FI912873 A FI 912873A FI 912873 A FI912873 A FI 912873A FI 912873 A FI912873 A FI 912873A FI 912873 A FI912873 A FI 912873A
Authority
FI
Finland
Prior art keywords
hydrogen
alkoxy
chem
halogen
polypeptidfoerening
Prior art date
Application number
FI912873A
Other languages
English (en)
Other versions
FI912873A0 (fi
Inventor
Toshiro Iwamoto
Akihiko Fujie
Kumiko Nitta
Yasuhisa Tsurumi
Nobuharu Shigematsu
Chiyoshi Kasahara
Motohiro Hino
Masakuni Okuhara
Kazuo Sakane
Kohji Kawabata
Hidenori Ohki
Original Assignee
Fujisawa Pharmaceutical Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB909013558A external-priority patent/GB9013558D0/en
Priority claimed from GB909023666A external-priority patent/GB9023666D0/en
Priority claimed from GB919101552A external-priority patent/GB9101552D0/en
Application filed by Fujisawa Pharmaceutical Co filed Critical Fujisawa Pharmaceutical Co
Publication of FI912873A0 publication Critical patent/FI912873A0/fi
Publication of FI912873A publication Critical patent/FI912873A/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K11/00—Depsipeptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K11/02—Depsipeptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof cyclic, e.g. valinomycins ; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/50—Cyclic peptides containing at least one abnormal peptide link
    • C07K7/54—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring
    • C07K7/56—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring the cyclisation not occurring through 2,4-diamino-butanoic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
FI912873A 1990-06-18 1991-06-14 Ny polypeptidfoerening och foerfarande foer dess framstaellning. FI912873A (fi)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB909013558A GB9013558D0 (en) 1990-06-18 1990-06-18 New polypeptide compound and a process for preparation thereof
GB909023666A GB9023666D0 (en) 1990-10-31 1990-10-31 Polypeptide compound and a process for preparation thereof
GB919101552A GB9101552D0 (en) 1991-01-24 1991-01-24 New polypeptide compound and a process for preparation thereof

Publications (2)

Publication Number Publication Date
FI912873A0 FI912873A0 (fi) 1991-06-14
FI912873A true FI912873A (fi) 1991-12-19

Family

ID=27265144

Family Applications (1)

Application Number Title Priority Date Filing Date
FI912873A FI912873A (fi) 1990-06-18 1991-06-14 Ny polypeptidfoerening och foerfarande foer dess framstaellning.

Country Status (20)

Country Link
US (1) US5376634A (fi)
EP (2) EP0462531B1 (fi)
JP (1) JP3307410B2 (fi)
KR (1) KR100199535B1 (fi)
CN (1) CN1040541C (fi)
AT (1) ATE143671T1 (fi)
AU (1) AU651347B2 (fi)
CA (1) CA2044746C (fi)
DE (1) DE69122432T2 (fi)
DK (1) DK0462531T3 (fi)
ES (1) ES2093658T3 (fi)
FI (1) FI912873A (fi)
GR (1) GR3021780T3 (fi)
HU (2) HUT58108A (fi)
IE (2) IE912046A1 (fi)
IL (1) IL98506A (fi)
NO (1) NO912347L (fi)
OA (1) OA09369A (fi)
PT (1) PT98023B (fi)
RU (1) RU2108342C1 (fi)

Families Citing this family (48)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8925593D0 (en) * 1989-11-13 1990-01-04 Fujisawa Pharmaceutical Co Fr901379 substance and preparation thereof
US5330973A (en) * 1990-03-19 1994-07-19 Merck & Co., Inc. Lipopeptide derivatives
US5386009A (en) * 1990-03-19 1995-01-31 Merck & Co. Inc. Lipopeptide derivatives
IE912046A1 (en) 1990-06-18 1991-12-18 Fujisawa Pharmaceutical Co New polypeptide compound and a process for preparation¹thereof
US5428009A (en) * 1990-07-16 1995-06-27 Merck & Co., Inc. Lipopeptide derivatives
USH1638H (en) * 1990-11-08 1997-03-04 Furuta; Takahisa Use of the polypeptide compound
US5385884A (en) * 1991-08-27 1995-01-31 Merck & Co. Inc. Lipopeptide derivatives
US6384013B1 (en) 1992-03-19 2002-05-07 Eli Lilly And Company Cyclic peptide antifungal agents and process for preparation thereof
US6743777B1 (en) 1992-03-19 2004-06-01 Eli Lilly And Company Cyclic peptide antifungal agents and process for preparation thereof
US5965525A (en) * 1992-03-19 1999-10-12 Eli Lilly And Company Cyclic peptide antifungal agents
JPH09500103A (ja) * 1993-05-04 1997-01-07 メルク エンド カンパニー インコーポレーテッド シクロヘキサペプチジルアミノアルキルエーテル
IL109615A (en) * 1993-05-17 2000-12-06 Fujisawa Pharmaceutical Co Cyclic polypeptide derivatives processes for the preparation thereof and pharmaceutical compositions containing the same
US5516757A (en) * 1994-09-16 1996-05-14 Merck & Co., Inc. Semi-synthetic lipopeptides, compositions containing said lipopeptides, and methods of use
ES2187575T3 (es) 1994-10-07 2003-06-16 Fujisawa Pharmaceutical Co Hexapeptidos ciclicos dotados de actividad antibiotica.
US5516756A (en) * 1994-10-31 1996-05-14 Merck & Co., Inc. Aza cyclohexapeptide compounds
JP2966936B2 (ja) * 1995-01-26 1999-10-25 メルク エンド カンパニー インコーポレーテッド 新規抗真菌シクロヘキサペプチド
US5646111A (en) * 1995-04-07 1997-07-08 Eli Lilly And Company Cyclic peptide antifungal Agents
US5618787A (en) * 1995-05-26 1997-04-08 Eli Lilly And Company Cyclic peptide antifungal agents
US5786325A (en) * 1995-05-26 1998-07-28 Eli Lilly And Company Cyclic peptide antifungal agents and methods of making and using
US5629290A (en) * 1995-05-26 1997-05-13 Eli Lilly And Company Cyclic peptide antifungal agents
US5652213A (en) * 1995-05-26 1997-07-29 Eli Lilly And Company Cyclic peptide antifungal agents
US5629289A (en) * 1995-07-25 1997-05-13 Eli Lilly And Company Cyclic peptide antifungal agents
US6146872A (en) 1996-06-13 2000-11-14 Fukisawa Pharmaceutical Co., Ltd. Cyclic lipopeptide acylase
AUPO371596A0 (en) * 1996-11-19 1996-12-12 Fujisawa Pharmaceutical Co., Ltd. New compound
BR9907967A (pt) 1998-02-09 2000-10-17 Fujisawa Pharmaceutical Co Composto de polipeptideo, processo para sua preparação, composição farmacêutica compreendendo dito composto, e seu uso.
EP1428531A1 (en) * 1998-05-11 2004-06-16 Takeda Chemical Industries, Ltd. Oxyiminoalkanoic acid derivatives with hypoglycemic and hypolipidemic activity
ES2233070T3 (es) 1998-08-20 2005-06-01 ELI LILLY & COMPANY Sintesis de analogos peptidicos ciclicos modificados en el anillo.
WO2000034315A2 (en) 1998-12-09 2000-06-15 Eli Lilly And Company Purification of echinocandin cyclopeptide compounds
KR20020003864A (ko) 1999-03-03 2002-01-15 피터 지. 스트링거 에키노칸딘/탄수화물 착물
DE60019902D1 (de) 1999-03-03 2005-06-09 Lilly Co Eli Echinocandin pharmazeutische zusammensetzungen
JP4063497B2 (ja) 1999-03-03 2008-03-19 イーライ リリー アンド カンパニー エキノカンジンアンモニウム塩結晶の形成およびアニオン交換
EP1156784A1 (en) 1999-03-03 2001-11-28 Eli Lilly And Company Processes for making pharmaceutical oral ecb formulations and compositions
AUPP999799A0 (en) 1999-04-27 1999-05-20 Fujisawa Pharmaceutical Co., Ltd. New compound
TWI233805B (en) * 1999-07-01 2005-06-11 Fujisawa Pharmaceutical Co Stabilized pharmaceutical composition in lyophilized form as antifungal agent
US20040082757A1 (en) * 2001-02-26 2004-04-29 Katsuhiko Ito Echinocandin derivatives, pharmaceutical compositions containing same and use thereof as drugs
KR20010098986A (ko) * 2001-07-27 2001-11-09 김종군 바르는 단열재(temp-coat)
US6991800B2 (en) 2002-06-13 2006-01-31 Vicuron Pharmaceuticals Inc. Antifungal parenteral products
US7459290B1 (en) 2004-03-30 2008-12-02 Iowa State University Research Foundation, Inc. Methods of using functional 30S subunits
WO2010064219A1 (en) 2008-12-04 2010-06-10 Ranbaxy Laboratories Limited Process for the preparation of a novel intermediate for caspofungin
ES2581562T3 (es) * 2010-09-29 2016-09-06 Shanghai Techwell Biopharmaceutical Co., Ltd Procedimiento para purificar compuestos lipopeptídicos cíclicos o sales de los mismos
AU2011307733B2 (en) * 2010-09-30 2015-03-26 Shanghai Techwell Biopharmaceutical Co., Ltd. Method for purifying cyclic lipopeptide or salt thereof
CN102533551B (zh) * 2010-12-15 2013-10-09 上海天伟生物制药有限公司 一种肽类抗生素的高产菌株及其制备方法和用途
CN102618604B (zh) * 2011-01-31 2014-09-03 上海天伟生物制药有限公司 一种环脂肽化合物的制备方法
RU2583262C2 (ru) 2011-04-20 2016-05-10 Кселлия Фармасьютикалз Апс Способ очистки микафунгина
CN102627688B (zh) * 2012-03-30 2014-12-31 上海天伟生物制药有限公司 一种高纯度环肽化合物及其制备方法和用途
CN102627689B (zh) * 2012-03-30 2014-08-06 上海天伟生物制药有限公司 一种环肽类化合物的水合物及其制备方法和用途
CN102659930B (zh) * 2012-03-30 2014-04-23 上海天伟生物制药有限公司 一种高纯度环肽类物质的晶体及其制备方法和用途
CN103387975A (zh) 2012-05-11 2013-11-13 上海天伟生物制药有限公司 一种固定化环脂肽酰基转移酶及其制备方法和用途

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1182812A (en) * 1979-12-13 1985-02-19 Bernard J. Abbott Process for the preparation of derivatives of cyclic peptide nuclei
US4293484A (en) * 1979-12-13 1981-10-06 Eli Lilly And Company Derivatives of A-30912H nucleus
CA1159450A (en) * 1979-12-13 1983-12-27 Manuel Debono Process for the preparation of derivatives of cyclic peptide nuclei
US4293482A (en) * 1979-12-13 1981-10-06 Eli Lilly And Company A-30912A Nucleus
US4293488A (en) * 1979-12-13 1981-10-06 Eli Lilly And Company Derivatives of A-30912B nucleus
US4293489A (en) * 1979-12-13 1981-10-06 Eli Lilly And Company Derivatives of A-30912A nucleus
DE3689525D1 (de) * 1985-07-17 1994-02-24 Hoechst Ag Neue Polypeptide mit blutgerinnungshemmender Wirkung, Verfahren zu deren Herstellung bzw. Gewinnung, deren Verwendung und diese enthaltende Mittel.
DE3886001T2 (de) * 1987-10-07 1994-05-26 Merck & Co Inc Fungizides Fermentationsprodukt.
DK173802B1 (da) * 1988-09-12 2001-11-05 Merck & Co Inc Præparat til behandling af Pneumocystis carinii infeksioner og anvendelse af et cyclohexapeptid til fremstilling af et lægemiddel mod Pneumocystis carinii infektioner
EP0450048A4 (en) * 1989-10-18 1992-12-02 City Of Hope Stable mammalian cell lines that express aromatase
GB8925593D0 (en) * 1989-11-13 1990-01-04 Fujisawa Pharmaceutical Co Fr901379 substance and preparation thereof
US5386009A (en) * 1990-03-19 1995-01-31 Merck & Co. Inc. Lipopeptide derivatives
US5330973A (en) * 1990-03-19 1994-07-19 Merck & Co., Inc. Lipopeptide derivatives
IE912046A1 (en) 1990-06-18 1991-12-18 Fujisawa Pharmaceutical Co New polypeptide compound and a process for preparation¹thereof
EP0486011A3 (en) * 1990-11-16 1992-07-15 Fujisawa Pharmaceutical Co., Ltd. Pharmaceutical composition against pneumocystis carinii

Also Published As

Publication number Publication date
HU211740A9 (en) 1995-12-28
EP0462531A2 (en) 1991-12-27
GR3021780T3 (en) 1997-02-28
EP0729974A1 (en) 1996-09-04
DE69122432D1 (de) 1996-11-07
HUT58108A (en) 1992-01-28
IL98506A (en) 1996-09-12
US5376634A (en) 1994-12-27
AU651347B2 (en) 1994-07-21
OA09369A (en) 1992-09-15
DK0462531T3 (da) 1996-11-18
EP0462531B1 (en) 1996-10-02
ATE143671T1 (de) 1996-10-15
NO912347L (no) 1991-12-19
CA2044746C (en) 2001-08-07
DE69122432T2 (de) 1997-03-20
RU2108342C1 (ru) 1998-04-10
EP0462531A3 (en) 1992-11-04
IE990233A1 (en) 2000-11-15
CN1059729A (zh) 1992-03-25
FI912873A0 (fi) 1991-06-14
NO912347D0 (no) 1991-06-17
IE912046A1 (en) 1991-12-18
KR920000788A (ko) 1992-01-29
CA2044746A1 (en) 1991-12-19
ES2093658T3 (es) 1997-01-01
CN1040541C (zh) 1998-11-04
KR100199535B1 (ko) 1999-06-15
JP3307410B2 (ja) 2002-07-24
JPH04352799A (ja) 1992-12-07
PT98023B (pt) 1998-11-30
IL98506A0 (en) 1992-07-15
PT98023A (pt) 1992-03-31
HU912014D0 (en) 1991-12-30
AU7843591A (en) 1992-01-16

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