FI912873A - Ny polypeptidfoerening och foerfarande foer dess framstaellning. - Google Patents

Ny polypeptidfoerening och foerfarande foer dess framstaellning. Download PDF

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Publication number
FI912873A
FI912873A FI912873A FI912873A FI912873A FI 912873 A FI912873 A FI 912873A FI 912873 A FI912873 A FI 912873A FI 912873 A FI912873 A FI 912873A FI 912873 A FI912873 A FI 912873A
Authority
FI
Finland
Prior art keywords
hydrogen
alkoxy
chem
halogen
polypeptidfoerening
Prior art date
Application number
FI912873A
Other languages
English (en)
Other versions
FI912873A0 (fi
Inventor
Toshiro Iwamoto
Akihiko Fujie
Kumiko Nitta
Yasuhisa Tsurumi
Nobuharu Shigematsu
Chiyoshi Kasahara
Motohiro Hino
Masakuni Okuhara
Kazuo Sakane
Kohji Kawabata
Hidenori Ohki
Original Assignee
Fujisawa Pharmaceutical Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB909013558A external-priority patent/GB9013558D0/en
Priority claimed from GB909023666A external-priority patent/GB9023666D0/en
Priority claimed from GB919101552A external-priority patent/GB9101552D0/en
Application filed by Fujisawa Pharmaceutical Co filed Critical Fujisawa Pharmaceutical Co
Publication of FI912873A0 publication Critical patent/FI912873A0/fi
Publication of FI912873A publication Critical patent/FI912873A/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K11/00—Depsipeptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K11/02—Depsipeptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof cyclic, e.g. valinomycins ; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/50—Cyclic peptides containing at least one abnormal peptide link
    • C07K7/54—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring
    • C07K7/56—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring the cyclisation not occurring through 2,4-diamino-butanoic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Measuring Pulse, Heart Rate, Blood Pressure Or Blood Flow (AREA)
  • Materials For Medical Uses (AREA)
  • Stringed Musical Instruments (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
FI912873A 1990-06-18 1991-06-14 Ny polypeptidfoerening och foerfarande foer dess framstaellning. FI912873A (fi)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB909013558A GB9013558D0 (en) 1990-06-18 1990-06-18 New polypeptide compound and a process for preparation thereof
GB909023666A GB9023666D0 (en) 1990-10-31 1990-10-31 Polypeptide compound and a process for preparation thereof
GB919101552A GB9101552D0 (en) 1991-01-24 1991-01-24 New polypeptide compound and a process for preparation thereof

Publications (2)

Publication Number Publication Date
FI912873A0 FI912873A0 (fi) 1991-06-14
FI912873A true FI912873A (fi) 1991-12-19

Family

ID=27265144

Family Applications (1)

Application Number Title Priority Date Filing Date
FI912873A FI912873A (fi) 1990-06-18 1991-06-14 Ny polypeptidfoerening och foerfarande foer dess framstaellning.

Country Status (20)

Country Link
US (1) US5376634A (fi)
EP (2) EP0729974A1 (fi)
JP (1) JP3307410B2 (fi)
KR (1) KR100199535B1 (fi)
CN (1) CN1040541C (fi)
AT (1) ATE143671T1 (fi)
AU (1) AU651347B2 (fi)
CA (1) CA2044746C (fi)
DE (1) DE69122432T2 (fi)
DK (1) DK0462531T3 (fi)
ES (1) ES2093658T3 (fi)
FI (1) FI912873A (fi)
GR (1) GR3021780T3 (fi)
HU (2) HUT58108A (fi)
IE (2) IE990233A1 (fi)
IL (1) IL98506A (fi)
NO (1) NO912347L (fi)
OA (1) OA09369A (fi)
PT (1) PT98023B (fi)
RU (1) RU2108342C1 (fi)

Families Citing this family (48)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8925593D0 (en) * 1989-11-13 1990-01-04 Fujisawa Pharmaceutical Co Fr901379 substance and preparation thereof
US5330973A (en) * 1990-03-19 1994-07-19 Merck & Co., Inc. Lipopeptide derivatives
US5386009A (en) * 1990-03-19 1995-01-31 Merck & Co. Inc. Lipopeptide derivatives
FI912873A (fi) 1990-06-18 1991-12-19 Fujisawa Pharmaceutical Co Ny polypeptidfoerening och foerfarande foer dess framstaellning.
US5428009A (en) * 1990-07-16 1995-06-27 Merck & Co., Inc. Lipopeptide derivatives
USH1638H (en) * 1990-11-08 1997-03-04 Furuta; Takahisa Use of the polypeptide compound
US5385884A (en) * 1991-08-27 1995-01-31 Merck & Co. Inc. Lipopeptide derivatives
US6384013B1 (en) 1992-03-19 2002-05-07 Eli Lilly And Company Cyclic peptide antifungal agents and process for preparation thereof
US6743777B1 (en) 1992-03-19 2004-06-01 Eli Lilly And Company Cyclic peptide antifungal agents and process for preparation thereof
US5965525A (en) * 1992-03-19 1999-10-12 Eli Lilly And Company Cyclic peptide antifungal agents
AU674233B2 (en) * 1993-05-04 1996-12-12 Merck & Co., Inc. Cyclohexapeptidyl aminoalkyl ethers
AU681119B2 (en) * 1993-05-17 1997-08-21 Fujisawa Pharmaceutical Co., Ltd. New polypeptide compound and a process for preparation thereof
US5516757A (en) * 1994-09-16 1996-05-14 Merck & Co., Inc. Semi-synthetic lipopeptides, compositions containing said lipopeptides, and methods of use
JP2897427B2 (ja) * 1994-10-07 1999-05-31 藤沢薬品工業株式会社 抗微生物活性を有する環状ヘキサペプチド化合物
US5516756A (en) * 1994-10-31 1996-05-14 Merck & Co., Inc. Aza cyclohexapeptide compounds
ATE206054T1 (de) * 1995-01-26 2001-10-15 Merck & Co Inc Neue fungizide cyclohexapeptide
US5646111A (en) * 1995-04-07 1997-07-08 Eli Lilly And Company Cyclic peptide antifungal Agents
US5618787A (en) * 1995-05-26 1997-04-08 Eli Lilly And Company Cyclic peptide antifungal agents
US5652213A (en) * 1995-05-26 1997-07-29 Eli Lilly And Company Cyclic peptide antifungal agents
US5629290A (en) * 1995-05-26 1997-05-13 Eli Lilly And Company Cyclic peptide antifungal agents
US5786325A (en) * 1995-05-26 1998-07-28 Eli Lilly And Company Cyclic peptide antifungal agents and methods of making and using
US5629289A (en) * 1995-07-25 1997-05-13 Eli Lilly And Company Cyclic peptide antifungal agents
US6146872A (en) * 1996-06-13 2000-11-14 Fukisawa Pharmaceutical Co., Ltd. Cyclic lipopeptide acylase
AUPO371596A0 (en) * 1996-11-19 1996-12-12 Fujisawa Pharmaceutical Co., Ltd. New compound
CN1240713C (zh) 1998-02-09 2006-02-08 藤泽药品工业株式会社 化合物
SK16412000A3 (sk) * 1998-05-11 2001-08-06 Takeda Chemical Industries, Ltd. Deriváty kyseliny oxyiminoalkánovej
AU765660B2 (en) 1998-08-20 2003-09-25 Eli Lilly And Company Ring modified cyclic peptide analogs
BR9916101A (pt) 1998-12-09 2002-06-04 Lilly Co Eli Purificação de compostos de ciclopeptìdeos equinocandinos
KR20010112302A (ko) 1999-03-03 2001-12-20 피터 지. 스트링거 제약학적 경구용 ｅｃｂ 조제물 및 조성물의 제조 방법
CA2362016A1 (en) 1999-03-03 2000-09-08 Kenneth Philip Moder Echinocandin/carbohydrate complexes
EP1582204B1 (en) 1999-03-03 2013-09-25 Eli Lilly & Company Echinocandin pharmaceutical formulations containing micelle-forming surfactants
DK1155034T3 (da) 1999-03-03 2007-01-08 Lilly Co Eli Dannelse og anionbytning af indre krystallinske echinocandin B-ammoniumsalte
AUPP999799A0 (en) 1999-04-27 1999-05-20 Fujisawa Pharmaceutical Co., Ltd. New compound
TWI233805B (en) * 1999-07-01 2005-06-11 Fujisawa Pharmaceutical Co Stabilized pharmaceutical composition in lyophilized form as antifungal agent
US20040082757A1 (en) * 2001-02-26 2004-04-29 Katsuhiko Ito Echinocandin derivatives, pharmaceutical compositions containing same and use thereof as drugs
KR20010098986A (ko) * 2001-07-27 2001-11-09 김종군 바르는 단열재(temp-coat)
US6991800B2 (en) 2002-06-13 2006-01-31 Vicuron Pharmaceuticals Inc. Antifungal parenteral products
US7459290B1 (en) 2004-03-30 2008-12-02 Iowa State University Research Foundation, Inc. Methods of using functional 30S subunits
WO2010064219A1 (en) 2008-12-04 2010-06-10 Ranbaxy Laboratories Limited Process for the preparation of a novel intermediate for caspofungin
US8927690B2 (en) 2010-09-29 2015-01-06 Shanghai Techwell Biopharmaceutical Co., Ltd. Process for purifying cyclolipopeptide compounds or the salts thereof
AU2011307733B2 (en) * 2010-09-30 2015-03-26 Shanghai Techwell Biopharmaceutical Co., Ltd. Method for purifying cyclic lipopeptide or salt thereof
CN102533551B (zh) 2010-12-15 2013-10-09 上海天伟生物制药有限公司 一种肽类抗生素的高产菌株及其制备方法和用途
CN102618604B (zh) * 2011-01-31 2014-09-03 上海天伟生物制药有限公司 一种环脂肽化合物的制备方法
AU2012244435B2 (en) 2011-04-20 2017-06-15 Xellia Pharmaceuticals Aps Method for purification of Micafungin
CN102659930B (zh) 2012-03-30 2014-04-23 上海天伟生物制药有限公司 一种高纯度环肽类物质的晶体及其制备方法和用途
CN102627689B (zh) 2012-03-30 2014-08-06 上海天伟生物制药有限公司 一种环肽类化合物的水合物及其制备方法和用途
CN102627688B (zh) * 2012-03-30 2014-12-31 上海天伟生物制药有限公司 一种高纯度环肽化合物及其制备方法和用途
CN103387975A (zh) 2012-05-11 2013-11-13 上海天伟生物制药有限公司 一种固定化环脂肽酰基转移酶及其制备方法和用途

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4293484A (en) * 1979-12-13 1981-10-06 Eli Lilly And Company Derivatives of A-30912H nucleus
CA1159450A (en) * 1979-12-13 1983-12-27 Manuel Debono Process for the preparation of derivatives of cyclic peptide nuclei
US4293482A (en) * 1979-12-13 1981-10-06 Eli Lilly And Company A-30912A Nucleus
US4293488A (en) * 1979-12-13 1981-10-06 Eli Lilly And Company Derivatives of A-30912B nucleus
US4293489A (en) * 1979-12-13 1981-10-06 Eli Lilly And Company Derivatives of A-30912A nucleus
CA1182812A (en) * 1979-12-13 1985-02-19 Bernard J. Abbott Process for the preparation of derivatives of cyclic peptide nuclei
EP0209061B1 (de) * 1985-07-17 1994-01-12 Hoechst Aktiengesellschaft Neue Polypeptide mit blutgerinnungshemmender Wirkung, Verfahren zu deren Herstellung bzw. Gewinnung, deren Verwendung und diese enthaltende Mittel
EP0311193B1 (en) * 1987-10-07 1993-12-01 Merck & Co. Inc. Antifungal fermentation product
DK173802B1 (da) * 1988-09-12 2001-11-05 Merck & Co Inc Præparat til behandling af Pneumocystis carinii infeksioner og anvendelse af et cyclohexapeptid til fremstilling af et lægemiddel mod Pneumocystis carinii infektioner
JPH04502261A (ja) * 1989-10-18 1992-04-23 シティ・オブ・ホープ アロマターゼを発現する安定な哺乳類細胞ライン
GB8925593D0 (en) * 1989-11-13 1990-01-04 Fujisawa Pharmaceutical Co Fr901379 substance and preparation thereof
US5386009A (en) * 1990-03-19 1995-01-31 Merck & Co. Inc. Lipopeptide derivatives
US5330973A (en) * 1990-03-19 1994-07-19 Merck & Co., Inc. Lipopeptide derivatives
FI912873A (fi) 1990-06-18 1991-12-19 Fujisawa Pharmaceutical Co Ny polypeptidfoerening och foerfarande foer dess framstaellning.
EP0486011A3 (en) * 1990-11-16 1992-07-15 Fujisawa Pharmaceutical Co., Ltd. Pharmaceutical composition against pneumocystis carinii

Also Published As

Publication number Publication date
CA2044746A1 (en) 1991-12-19
HU912014D0 (en) 1991-12-30
CN1059729A (zh) 1992-03-25
IL98506A (en) 1996-09-12
HUT58108A (en) 1992-01-28
GR3021780T3 (en) 1997-02-28
DE69122432T2 (de) 1997-03-20
CN1040541C (zh) 1998-11-04
EP0462531A2 (en) 1991-12-27
IL98506A0 (en) 1992-07-15
DE69122432D1 (de) 1996-11-07
ATE143671T1 (de) 1996-10-15
US5376634A (en) 1994-12-27
JP3307410B2 (ja) 2002-07-24
IE912046A1 (en) 1991-12-18
HU211740A9 (en) 1995-12-28
PT98023A (pt) 1992-03-31
OA09369A (en) 1992-09-15
IE990233A1 (en) 2000-11-15
AU7843591A (en) 1992-01-16
AU651347B2 (en) 1994-07-21
FI912873A0 (fi) 1991-06-14
KR920000788A (ko) 1992-01-29
NO912347D0 (no) 1991-06-17
ES2093658T3 (es) 1997-01-01
PT98023B (pt) 1998-11-30
CA2044746C (en) 2001-08-07
NO912347L (no) 1991-12-19
EP0729974A1 (en) 1996-09-04
RU2108342C1 (ru) 1998-04-10
JPH04352799A (ja) 1992-12-07
EP0462531A3 (en) 1992-11-04
KR100199535B1 (ko) 1999-06-15
DK0462531T3 (da) 1996-11-18
EP0462531B1 (en) 1996-10-02

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