DK0788511T3 - Cykliske hexapeptider med antibiotisk aktivitet - Google Patents

Cykliske hexapeptider med antibiotisk aktivitet

Info

Publication number
DK0788511T3
DK0788511T3 DK95932935T DK95932935T DK0788511T3 DK 0788511 T3 DK0788511 T3 DK 0788511T3 DK 95932935 T DK95932935 T DK 95932935T DK 95932935 T DK95932935 T DK 95932935T DK 0788511 T3 DK0788511 T3 DK 0788511T3
Authority
DK
Denmark
Prior art keywords
antibiotic activity
cyclic hexapeptides
hexapeptides
cyclic
antibiotic
Prior art date
Application number
DK95932935T
Other languages
Danish (da)
English (en)
Inventor
Hidenori Ohki
Akira Yamada
Hisashi Takasugi
Masaki Tomishima
Original Assignee
Fujisawa Pharmaceutical Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26305774&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK0788511(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from GB9420425A external-priority patent/GB9420425D0/en
Priority claimed from GBGB9508745.8A external-priority patent/GB9508745D0/en
Application filed by Fujisawa Pharmaceutical Co filed Critical Fujisawa Pharmaceutical Co
Application granted granted Critical
Publication of DK0788511T3 publication Critical patent/DK0788511T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/50—Cyclic peptides containing at least one abnormal peptide link
    • C07K7/54—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring
    • C07K7/56—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring the cyclisation not occurring through 2,4-diamino-butanoic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
DK95932935T 1994-10-07 1995-09-29 Cykliske hexapeptider med antibiotisk aktivitet DK0788511T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB9420425A GB9420425D0 (en) 1994-10-07 1994-10-07 New compound
GBGB9508745.8A GB9508745D0 (en) 1995-04-28 1995-04-28 New compound
PCT/JP1995/001983 WO1996011210A1 (en) 1994-10-07 1995-09-29 Cyclic hexapeptides having antibiotic activity

Publications (1)

Publication Number Publication Date
DK0788511T3 true DK0788511T3 (da) 2003-03-31

Family

ID=26305774

Family Applications (1)

Application Number Title Priority Date Filing Date
DK95932935T DK0788511T3 (da) 1994-10-07 1995-09-29 Cykliske hexapeptider med antibiotisk aktivitet

Country Status (27)

Country Link
US (2) US6107458A (es)
EP (1) EP0788511B1 (es)
JP (2) JP2897427B2 (es)
KR (1) KR100353303B1 (es)
CN (1) CN1203089C (es)
AR (1) AR041770A1 (es)
AT (1) ATE229541T1 (es)
AU (1) AU696949B2 (es)
BR (2) BRPI9504791B8 (es)
CA (1) CA2202058C (es)
DE (2) DE69529172T2 (es)
DK (1) DK0788511T3 (es)
ES (1) ES2187575T3 (es)
FI (1) FI119988B (es)
FR (1) FR08C0028I2 (es)
HK (1) HK1004136A1 (es)
HU (1) HU228151B1 (es)
IL (1) IL115484A (es)
LU (1) LU91452I2 (es)
MX (1) MX9702531A (es)
NL (1) NL300352I2 (es)
NO (2) NO328483B1 (es)
OA (1) OA10475A (es)
PT (1) PT788511E (es)
RU (1) RU2165423C2 (es)
TR (1) TR199501229A2 (es)
WO (1) WO1996011210A1 (es)

Families Citing this family (58)

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US5696084A (en) * 1996-08-16 1997-12-09 Abbott Laboratories Amino-lipopetide antifungal agents
AUPO371596A0 (en) * 1996-11-19 1996-12-12 Fujisawa Pharmaceutical Co., Ltd. New compound
AUPO381496A0 (en) * 1996-11-25 1996-12-19 Fujisawa Pharmaceutical Co., Ltd. New compound
US6291680B1 (en) * 1997-06-18 2001-09-18 Fujisawa Pharmaceutical Co., Ltd. Production process
KR100396737B1 (ko) * 1998-02-09 2003-09-13 후지사와 야꾸힝 고교 가부시키가이샤 신규 화합물
AU756792B2 (en) * 1998-02-09 2003-01-23 Fujisawa Pharmaceutical Co., Ltd. New compound
US7084279B1 (en) * 1999-02-11 2006-08-01 Emisphere Technologies Inc. Oxadiazole compounds and compositions for delivering active agents
JP4854855B2 (ja) * 1999-02-11 2012-01-18 エミスフェアー・テクノロジーズ・インク オキサジアゾール化合物及び活性剤をデリバリーするための組成物
AUPP999799A0 (en) 1999-04-27 1999-05-20 Fujisawa Pharmaceutical Co., Ltd. New compound
AUPQ066399A0 (en) * 1999-05-31 1999-06-24 Fujisawa Pharmaceutical Co., Ltd. Antifungal combination use
TWI233805B (en) * 1999-07-01 2005-06-11 Fujisawa Pharmaceutical Co Stabilized pharmaceutical composition in lyophilized form as antifungal agent
AU6564000A (en) * 1999-07-27 2001-02-13 Aventis Pharma Deutschland Gmbh Novel cyclohexapeptide compounds, processes for their production and their use as a pharmaceutical
AUPQ462399A0 (en) * 1999-12-13 2000-01-13 Fujisawa Pharmaceutical Co., Ltd. New use
TWI250992B (en) 2000-02-21 2006-03-11 Astellas Pharma Inc Polypeptide compounds for the prophylactic and/or therapeutic treatment of infectious diseases caused by pathogenic microorganisms
ES2191516B1 (es) * 2000-07-28 2005-01-01 Consejo Superior De Investigaciones Cientificas Antibioticos antifungicos de naturaleza peptidica inhibidores de la germinacion y el crecimiento de hongos fitopatogenos.
AUPQ938700A0 (en) * 2000-08-14 2000-09-07 Fujisawa Pharmaceutical Co., Ltd. Antifungal combination use
WO2002060446A1 (en) 2001-01-29 2002-08-08 Shionogi & Co., Ltd. Medicinal preparation containing 5-methyl-1-phenyl-2-(1h)-pyridone as active ingredient
JP2005053782A (ja) * 2001-08-31 2005-03-03 Fujisawa Pharmaceut Co Ltd 環状リポペプチド化合物の新規結晶
EP2266590A3 (en) 2002-02-22 2011-04-20 Shire LLC Active agent delivery sytems and methods for protecting and administering active agents
JP4784093B2 (ja) * 2002-08-08 2011-09-28 アステラス製薬株式会社 イソオキサゾリル安息香酸の製造法
AU2003903205A0 (en) * 2003-06-23 2003-07-10 Fujisawa Pharmaceutical Co., Ltd. New compound
EP1654036B1 (en) * 2003-07-22 2007-12-26 Theravance, Inc. Use of an echinocandin antifungal agent in combination with a glycopeptide antibacterial agent
AU2004273029A1 (en) * 2003-09-05 2005-03-24 Merck & Co., Inc. Stationary phases and a purification process using the stationary phases
JP4765627B2 (ja) * 2003-09-22 2011-09-07 Ｍｓｄ株式会社 新規ピペリジン誘導体
US7476673B2 (en) * 2003-12-30 2009-01-13 Allergan, Inc. Disubstituted chalcone oximes as selective agonists of RARγ retinoid receptors
WO2005113523A1 (en) * 2004-05-20 2005-12-01 Foldrx Pharmaceuticals, Inc. 2-((hetero) aryl)-benzoxazole compounds and derivatives, compositions and methods for stabilizing transthyretin and inhibiting transthyretin misfolding
TW200626138A (en) 2004-09-20 2006-08-01 Xenon Pharmaceuticals Inc Heterocyclic derivatives and their use as therapeutic agents
WO2006034441A1 (en) 2004-09-20 2006-03-30 Xenon Pharmaceuticals Inc. Heterocyclic derivatives and their use as stearoyl-coa desaturase inhibitors
JP5094398B2 (ja) 2004-09-20 2012-12-12 ゼノン・ファーマシューティカルズ・インコーポレイテッド 複素環式誘導体およびステアロイル−ＣｏＡデサチュラーゼのメディエータとしてのそれらの使用
MX2007003318A (es) 2004-09-20 2007-05-18 Xenon Pharmaceuticals Inc Derivados heterociclicos y su uso como agentes terapeuticos.
CA2580857A1 (en) 2004-09-20 2006-09-28 Xenon Pharmaceuticals Inc. Heterocyclic derivatives and their use as stearoyl-coa desaturase inhibitors
WO2006034341A2 (en) 2004-09-20 2006-03-30 Xenon Pharmaceuticals Inc. Pyridazine derivatives for inhibiting human stearoyl-coa-desaturase
WO2006034440A2 (en) 2004-09-20 2006-03-30 Xenon Pharmaceuticals Inc. Heterocyclic derivatives and their use as stearoyl-coa desaturase inhibitors
EP1799659A1 (en) * 2004-10-13 2007-06-27 PTC Therapeutics, Inc. Compounds for nonsense suppression, and methods for their use
AU2006343359A1 (en) 2005-06-03 2007-11-15 Xenon Pharmaceuticals Inc. Aminothiazole derivatives as human stearoyl-coa desaturase inhibitors
KR20080066938A (ko) * 2005-10-07 2008-07-17 깃세이 야쿠힌 고교 가부시키가이샤 질소 함유 복소환 화합물 및 그것을 함유하는 의약 조성물
CN101516387B (zh) * 2006-07-26 2014-06-04 桑多斯股份公司 卡泊芬净制剂
US8853392B2 (en) 2007-06-03 2014-10-07 Vanderbilt University Benzamide mGluR5 positive allosteric modulators and methods of making and using same
HUE036519T2 (hu) 2007-08-13 2018-07-30 Monsanto Technology Llc Készítmények és eljárások nematódák irtására
EP2204379A4 (en) * 2007-10-29 2010-12-22 Astellas Pharma Inc POLYPEPTIDE COMPOUND
US8034806B2 (en) 2007-11-02 2011-10-11 Vanderbilt University Bicyclic mGluR5 positive allosteric modulators and methods of making and using same
CN102076670B (zh) * 2008-06-24 2013-05-22 Irm责任有限公司 调节g蛋白偶联受体的化合物和方法
US9394340B2 (en) 2009-03-24 2016-07-19 Cadila Healthcare Limited Purification process for lipopeptides
BR112013023531A2 (pt) * 2011-04-04 2016-12-06 Xellia Pharmaceuticals Aps processo de um único vaso para a fabricação de micafungina ou de um sal desta
ES2547827T3 (es) 2011-04-20 2015-10-08 Axellia Pharmaceuticals Aps Procedimiento para la purificación de la micafungina
CN102775476B (zh) * 2011-05-12 2015-01-07 上海天伟生物制药有限公司 一种米卡芬净钠盐的制备方法
JP6130827B2 (ja) 2011-05-17 2017-05-17 塩野義製薬株式会社 ヘテロ環化合物
CN103917531B (zh) * 2011-09-09 2016-08-24 桑多斯股份公司 米卡芬净中间体的制备
CN102627689B (zh) * 2012-03-30 2014-08-06 上海天伟生物制药有限公司 一种环肽类化合物的水合物及其制备方法和用途
CN102659930B (zh) * 2012-03-30 2014-04-23 上海天伟生物制药有限公司 一种高纯度环肽类物质的晶体及其制备方法和用途
CN102627688B (zh) 2012-03-30 2014-12-31 上海天伟生物制药有限公司 一种高纯度环肽化合物及其制备方法和用途
WO2015180682A1 (zh) * 2014-05-29 2015-12-03 上海天伟生物制药有限公司 一种环肽类化合物的溶剂合物及其制备方法和用途
EP3226885A4 (en) * 2014-10-07 2018-07-18 Alaparthi, Lakshmi Prasad Intermediates and processes to prepare micafungin
CA2937365C (en) 2016-03-29 2018-09-18 F. Hoffmann-La Roche Ag Granulate formulation of 5-methyl-1-phenyl-2-(1h)-pyridone and method of making the same
EP3485873A1 (en) 2017-11-17 2019-05-22 Cadila Healthcare Limited Stable pharmaceutical injectable compositions of micafungin
CN108752430B (zh) * 2018-05-31 2022-02-18 杭州中美华东制药有限公司 米卡芬净钠新晶型及其制备方法
WO2020013116A1 (ja) * 2018-07-10 2020-01-16 京都薬品工業株式会社 Ｐｔｐ－１ｂ阻害剤およびその用途
CN110734408A (zh) * 2019-10-22 2020-01-31 重庆康乐制药有限公司 一种米卡芬净类衍生物侧链中间体的制备方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IE990233A1 (en) * 1990-06-18 2000-11-15 Fujisawa Pharmaceutical Co New Polypeptide Compound and a Process for Preparation thereof
NZ247149A (en) * 1992-03-19 1996-10-28 Lilly Co Eli Cyclic peptide antifungal agents and compositions thereof

Also Published As

Publication number Publication date
HK1004136A1 (en) 1998-11-20
NL300352I1 (nl) 2008-08-01
BRPI9504791B8 (pt) 2019-12-31
OA10475A (en) 2002-04-08
DE69529172T2 (de) 2003-04-17
CA2202058C (en) 2007-11-06
JPH10324695A (ja) 1998-12-08
PT788511E (pt) 2003-04-30
FR08C0028I1 (es) 2008-08-15
RU2165423C2 (ru) 2001-04-20
NL300352I2 (nl) 2008-11-03
ATE229541T1 (de) 2002-12-15
FI971397A (fi) 1997-05-27
BR9504791B1 (pt) 2010-10-05
WO1996011210A1 (en) 1996-04-18
KR100353303B1 (ko) 2003-01-15
NO2010016I1 (no) 2010-08-16
BR9504791A (pt) 1996-10-22
AU3578095A (en) 1996-05-02
JPH10507174A (ja) 1998-07-14
EP0788511B1 (en) 2002-12-11
US6265536B1 (en) 2001-07-24
CA2202058A1 (en) 1996-04-18
CN1168675A (zh) 1997-12-24
EP0788511A1 (en) 1997-08-13
AR041770A1 (es) 2005-06-01
FI119988B (fi) 2009-05-29
MX9702531A (es) 1997-06-28
FI971397A0 (fi) 1997-04-04
HU228151B1 (en) 2012-12-28
TR199501229A2 (tr) 1996-07-21
ES2187575T3 (es) 2003-06-16
IL115484A (en) 2000-07-16
DE122008000025I1 (de) 2008-08-21
DE69529172D1 (de) 2003-01-23
CN1203089C (zh) 2005-05-25
US6107458A (en) 2000-08-22
NO971544L (no) 1997-06-04
FR08C0028I2 (es) 2009-11-20
JP3518665B2 (ja) 2004-04-12
IL115484A0 (en) 1996-01-19
NO2010016I2 (no) 2011-10-17
NO971544D0 (no) 1997-04-04
LU91452I2 (fr) 2008-08-04
NO328483B1 (no) 2010-03-01
DE122008000025I2 (de) 2011-02-17
AU696949B2 (en) 1998-09-24
JP2897427B2 (ja) 1999-05-31
KR970707150A (ko) 1997-12-01
HUT77736A (hu) 1998-07-28

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