MX371331B - Inhibidores de la proteina cinasa dependiente de acido desoxirribonucleico(adn-pk). - Google Patents

Inhibidores de la proteina cinasa dependiente de acido desoxirribonucleico(adn-pk).

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Publication number
MX371331B
MX371331B MX2018004672A MX2018004672A MX371331B MX 371331 B MX371331 B MX 371331B MX 2018004672 A MX2018004672 A MX 2018004672A MX 2018004672 A MX2018004672 A MX 2018004672A MX 371331 B MX371331 B MX 371331B
Authority
MX
Mexico
Prior art keywords
inhibitors
dna
compounds
compositions
disorders
Prior art date
Application number
MX2018004672A
Other languages
English (en)
Spanish (es)
Inventor
Deng Hongbo
S Charifson Paul
P Duffy John
Gao Huai
M Kennedy Joseph
Michael Cottrell Kevin
Giroux Simon
Green Jeremy
Lee Jackson Katrina
A Morris Mark
Charles Pierce Albert
D Waal Nathan
J Lauffer David
Willem Ledeboer Mark
Li Pan
Xu Jinwang
Patrick Maxwell John
Original Assignee
Vertex Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Vertex Pharma filed Critical Vertex Pharma
Publication of MX371331B publication Critical patent/MX371331B/es

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    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/53—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with three nitrogens as the only ring hetero atoms, e.g. chlorazanil, melamine
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    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/5375—1,4-Oxazines, e.g. morpholine
    • A61K31/5377—1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
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