MX344857B - Metodo y material para el acomplejamiento activado en el sitio de moleculas biologicas. - Google Patents

Metodo y material para el acomplejamiento activado en el sitio de moleculas biologicas.

Info

Publication number
MX344857B
MX344857B MX2011009242A MX2011009242A MX344857B MX 344857 B MX344857 B MX 344857B MX 2011009242 A MX2011009242 A MX 2011009242A MX 2011009242 A MX2011009242 A MX 2011009242A MX 344857 B MX344857 B MX 344857B
Authority
MX
Mexico
Prior art keywords
biologic molecules
combined
site activated
complexing
methods
Prior art date
Application number
MX2011009242A
Other languages
English (en)
Other versions
MX2011009242A (es
Inventor
l huang Alexander
Wu Gin
Original Assignee
Metaactiv Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Metaactiv Inc filed Critical Metaactiv Inc
Publication of MX2011009242A publication Critical patent/MX2011009242A/es
Publication of MX344857B publication Critical patent/MX344857B/es

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/82Theaceae (Tea family), e.g. camellia
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N59/00Biocides, pest repellants or attractants, or plant growth regulators containing elements or inorganic compounds
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N65/00Biocides, pest repellants or attractants, or plant growth regulators containing material from algae, lichens, bryophyta, multi-cellular fungi or plants, or extracts thereof
    • A01N65/08Magnoliopsida [dicotyledons]
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K20/00Accessory food factors for animal feeding-stuffs
    • A23K20/10Organic substances
    • A23K20/111Aromatic compounds
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/105Plant extracts, their artificial duplicates or their derivatives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/045Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A61K31/05Phenols
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/12Ketones
    • A61K31/122Ketones having the oxygen directly attached to a ring, e.g. quinones, vitamin K1, anthralin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • A61K33/40Peroxides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/22Anacardiaceae (Sumac family), e.g. smoketree, sumac or poison oak
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43Enzymes; Proenzymes; Derivatives thereof
    • A61K38/44Oxidoreductases (1)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/12Antidiarrhoeals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/02Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07GCOMPOUNDS OF UNKNOWN CONSTITUTION
    • C07G1/00Lignin; Lignin derivatives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K1/00General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/107General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides
    • C07K1/1072General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides by covalent attachment of residues or functional groups
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Mycology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Botany (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Polymers & Plastics (AREA)
  • Medical Informatics (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Zoology (AREA)
  • Food Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Inorganic Chemistry (AREA)
  • Agronomy & Crop Science (AREA)
  • Environmental Sciences (AREA)
  • Dentistry (AREA)
  • Wood Science & Technology (AREA)
  • Plant Pathology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Animal Husbandry (AREA)
  • Analytical Chemistry (AREA)
  • Biophysics (AREA)

Abstract

La presente invención se refiere a un proceso para preparar una composición antibacterianas que comprende las etapas de: a) combinar cáscara de granada con agua y calentamiento de 80°C a 150°C para desnaturalizar sustancialmente enzimas endógenas a la cáscara de granada; y b) añadir desde 1% hasta menos del10% de peróxido de hidrógeno al producto obtenido de la etapa (a).
MX2011009242A 2009-03-04 2010-03-01 Metodo y material para el acomplejamiento activado en el sitio de moleculas biologicas. MX344857B (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US20926009P 2009-03-04 2009-03-04
PCT/US2010/025805 WO2010101844A1 (en) 2009-03-04 2010-03-01 Method and material for site activated complexing of biologic molecules

Publications (2)

Publication Number Publication Date
MX2011009242A MX2011009242A (es) 2012-02-28
MX344857B true MX344857B (es) 2017-01-10

Family

ID=42709967

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2011009242A MX344857B (es) 2009-03-04 2010-03-01 Metodo y material para el acomplejamiento activado en el sitio de moleculas biologicas.

Country Status (23)

Country Link
US (7) US8343552B2 (es)
EP (1) EP2403938B1 (es)
JP (3) JP2012519690A (es)
KR (1) KR101790352B1 (es)
CN (1) CN102421891B (es)
AU (1) AU2010221579B2 (es)
BR (1) BRPI1006287A2 (es)
CA (1) CA2754226C (es)
DK (1) DK2403938T3 (es)
ES (1) ES2791485T3 (es)
HK (1) HK1164916A1 (es)
HR (1) HRP20200392T1 (es)
HU (1) HUE049150T2 (es)
IL (2) IL214951A (es)
MX (1) MX344857B (es)
MY (1) MY172676A (es)
PH (2) PH12015502712B1 (es)
PL (1) PL2403938T3 (es)
RU (1) RU2571924C2 (es)
SG (3) SG10201502453SA (es)
TW (2) TWI632856B (es)
WO (1) WO2010101844A1 (es)
ZA (1) ZA201106974B (es)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8734867B2 (en) 2007-12-28 2014-05-27 Liveleaf, Inc. Antibacterial having an extract of pomegranate combined with hydrogen peroxide
SG10201502453SA (en) * 2009-03-04 2015-05-28 Liveleaf Inc Method and material for site activated complexing of biologic molecules
US9192635B2 (en) 2011-06-24 2015-11-24 Liveleaf, Inc. Method of treating damaged mucosal or gastrointestinal tissue by administering a composition comprising a mixture of pomegranate and green tea extracts and releasably bound hydrogen peroxide
US8722040B2 (en) * 2011-06-24 2014-05-13 Liveleaf, Inc. Site-activated binding systems that selectively increase the bioactivity of phenolic compounds at target sites
CN103155953A (zh) * 2011-12-19 2013-06-19 陕西恒田化工有限公司 一种石榴皮多酚植物杀菌剂、用途以及制备方法
US20150328258A1 (en) * 2012-05-30 2015-11-19 Ibh Ventures, Llc Polyphenol-reactive oxygen species compositions and methods
US9526754B1 (en) * 2012-11-26 2016-12-27 Manuel Serrano Plant polyphenols extraction and activation thereof
US8716351B1 (en) 2012-12-23 2014-05-06 Liveleaf, Inc. Methods of treating gastrointestinal spasms
US9962364B2 (en) 2012-12-26 2018-05-08 A-Z Ltd. Wound healing accelerator
JP6825913B2 (ja) 2014-04-30 2021-02-03 マトケ・ホールディングス・リミテッド 抗菌組成物
WO2015192136A1 (en) * 2014-06-13 2015-12-17 Liveleaf, Inc. Non-toxic agent for a broad-spectrum, bactericidal or bacteriostatic treatment of antibiotic-resistant bacteria in animals
MX2017015247A (es) 2015-06-01 2018-08-28 Xeno Biosciences Inc Metodos y composiciones para modular la microbiota intestinal y para manejar el peso.
CN110520111B (zh) * 2016-11-30 2023-12-19 塞诺生物科学股份有限公司 用以管理体重和调节肠道微生物群的药物制剂和方法
CN107094996B (zh) * 2017-04-24 2020-07-24 浙江省农业科学院 一种含石榴皮复合植物提取物及其制备方法和应用
CN107114562B (zh) * 2017-04-24 2020-08-14 浙江省农业科学院 一种抗炎兼具抑菌和抗氧化功能的复合型植物水提物及其制备方法和应用
WO2019036686A1 (en) * 2017-08-17 2019-02-21 Apeel Technology, Inc. PREVENTING PHYSIOLOGICAL DETERIORATION AFTER HARVEST USING SULFUR DONOR COMPOUNDS
GB201716986D0 (en) 2017-10-16 2017-11-29 Matoke Holdings Ltd Antimicrobial compositions
IT201800004842A1 (it) * 2018-04-24 2019-10-24 Sistema di cottura
CN108822184A (zh) * 2018-04-25 2018-11-16 浙江工业大学 一种蛋白功能改性的方法
CN109251865B (zh) * 2018-09-30 2021-06-15 哈尔滨工业大学 一种小球藻细胞表面耗氧保护层的制备方法
CN109297916B (zh) * 2018-11-20 2021-03-30 中国农业科学院农产品加工研究所 分析多酚化合物氧化产物的人工神经网络及预测方法
CN109699954A (zh) * 2019-03-08 2019-05-03 合浦果香园食品有限公司 一种制备海参水果馅料的方法
JP7381251B2 (ja) * 2019-08-23 2023-11-15 セッツ株式会社 抗ノロウイルス剤、消毒剤及び洗浄剤
CN111713510B (zh) * 2020-06-08 2021-11-23 西北农林科技大学 五倍子提取物用于制备植物源诱抗剂的应用及诱抗剂
CN111777979A (zh) * 2020-07-16 2020-10-16 江苏明天胶业有限公司 一种高强度耐候型改性硅烷密封胶及其制备工艺
WO2022016131A1 (en) * 2020-07-17 2022-01-20 Scientlce, Llc Anti-fouling and foul-releasing compositions and methods of making and using same
WO2022223736A1 (en) 2021-04-23 2022-10-27 Aurena Laboratories Holding Ab Transition metal oxide adducts for regulated generation of reactive oxygen species
NL2029251B1 (nl) 2021-09-24 2023-03-31 Cindro Holding B V Gestabiliseerd waterstofperoxide

Family Cites Families (114)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB191400001A (en) * 1913-01-10 1915-05-20 Loche & Cie Soc Improvements in or relating to Brooms or the like.
US1844018A (en) * 1929-04-18 1932-02-09 Mead Res Engineering Company Method of preparing tanning substances
DE530650C (de) * 1930-12-09 1931-07-31 Hoffmann La Roche & Co Akt Ges Verfahren zur Herstellung von Protocatechualdehyd und seinen Substitutionsprodukten
US1965458A (en) * 1932-05-18 1934-07-03 Hoffmann La Roche Process for the manufacture of aromatic hydroxy aldehydes
US3484248A (en) * 1967-07-03 1969-12-16 Lipton Inc Thomas J Alkaline conversion of green tea using hydrogen peroxide
GB1204585A (en) * 1968-01-23 1970-09-09 Tenco Brooke Bond Ltd Improvements in or relating to the fermentation of tea
US3817835A (en) * 1969-03-26 1974-06-18 Squibb & Sons Inc Process for the production of antimicrobial agents
US3692904A (en) * 1970-05-25 1972-09-19 Daiichi Seiyaku Co Method for treating scours in domestic livestock
US3824184A (en) * 1970-09-04 1974-07-16 Economics Lab Slime control in industrial waters
GB1377396A (en) * 1971-04-26 1974-12-18 Unilever Ltd Instant tea powder
IT986371B (it) * 1972-06-02 1975-01-30 Degussa Procedimento per la produzione di percarbonato alcalino
US3860694A (en) * 1972-08-31 1975-01-14 Du Pont Process for the preparation of perhydrates
JPS5429599B2 (es) * 1974-12-28 1979-09-25
SE7601543L (sv) * 1975-02-21 1976-08-23 Snam Progetti Forfarande for extrahering av fenoler och oligosackarider ur vegetabiliskt material
US4171280A (en) 1977-11-03 1979-10-16 The Clorox Company Powder percarbonate bleach and formation thereof
US4171281A (en) * 1978-02-03 1979-10-16 Bystrenin Mikhail N Graphitization and reducing charge
US4514334A (en) * 1979-05-31 1985-04-30 General Electric Company Polyphenolic compounds
FR2486523A1 (fr) * 1980-07-11 1982-01-15 Rhone Poulenc Ind Procede de preparation de polyphenols comportant eventuellement un groupement aldehyde
US4623465A (en) * 1981-04-20 1986-11-18 Massachusetts Institute Of Technology Removal of combined organic substances from aqueous solutions
US4472302A (en) * 1983-03-09 1984-09-18 Merck & Co., Inc. Heat shock process for the isolation of bacterial protein
US4472602A (en) * 1983-08-11 1984-09-18 At&T Technologies, Inc. Telephone set with transducer/ringer
US5141611A (en) * 1985-05-16 1992-08-25 Memtec Limited Removing and recovering plant polyphenols
US4829001A (en) * 1985-11-08 1989-05-09 Minnesota Mining And Manufacturing Company Enzymatic neutralization of hydrogen peroxide
US4647952A (en) * 1985-11-13 1987-03-03 The Mead Corporation Phenolic developer resins
GB8528307D0 (en) * 1985-11-18 1985-12-24 Beecham Group Plc Veterinary compositions
US4696757A (en) 1986-06-16 1987-09-29 American Home Products Corporation Stable hydrogen peroxide gels
US5296376A (en) * 1986-11-04 1994-03-22 Imperial Chemical Industries Plc DNA, constructs, cells and plants derived therefrom
US4966762A (en) * 1988-10-06 1990-10-30 Fmc Corporation Process for manufacturing a soda ash peroxygen carrier
JPH0791302B2 (ja) 1989-03-29 1995-10-04 キッコーマン株式会社 エラグ酸の製造法
US5231193A (en) * 1989-03-29 1993-07-27 Kikkoman Corporation Process for producing ellagic acid
US5756090A (en) * 1991-02-21 1998-05-26 Eoe, Inc. Oxygen activatable formulations for disinfection or sterilization
US5389369A (en) * 1991-02-21 1995-02-14 Exoxemis, Inc. Halo peroxidase containing compositions for killing yeast and sporular microorganisms
US5208010A (en) * 1991-06-17 1993-05-04 Dental Concepts Inc. Tooth whitening dentifrice
CN1079393A (zh) * 1992-06-05 1993-12-15 郭干举 治疗慢性胃炎复方五倍子成药方法
US5260021A (en) * 1992-06-29 1993-11-09 Allergan, Inc. Hydrogen peroxide-containing gels and contact lens disinfecting using same
EP0606454A1 (en) 1992-07-30 1994-07-20 Keygene N.V. Dna constructs, cells and plants derived therefrom
DK144392D0 (da) * 1992-12-01 1992-12-01 Novo Nordisk As Aktivering af enzymer
US5328706A (en) * 1993-04-29 1994-07-12 Endico Felix W Food manufacturing process utilizing hydrogen peroxide for microbial control
US6068862A (en) * 1993-06-30 2000-05-30 Taiyo Kagaku Co., Ltd. Tea-derived feed additive and animal feed containing the same
US5653746A (en) * 1994-03-08 1997-08-05 Meadox Medicals, Inc. Radially expandable tubular prosthesis
US5661170A (en) * 1994-03-21 1997-08-26 Woodward Laboratories, Inc. Antimicrobial compositions and methods for using the same
US5614501A (en) * 1994-07-21 1997-03-25 The University Of Montana Compositions and methods for animal husbandry and for treating gastrointestinal disorders
TW449485B (en) 1995-03-31 2001-08-11 Colgate Palmolive Co Skin care products containing anti itching/anti irritant agents
US5824414A (en) * 1995-04-28 1998-10-20 Mitsui Chemicals, Inc. Preparation of spherical polyphenol particles
US7048906B2 (en) * 1995-05-17 2006-05-23 Cedars-Sinai Medical Center Methods of diagnosing and treating small intestinal bacterial overgrowth (SIBO) and SIBO-related conditions
US5839369A (en) * 1995-10-20 1998-11-24 Eastman Kodak Company Method of controlled laser imaging of zirconia alloy ceramic lithographic member to provide localized melting in exposed areas
US6063428A (en) * 1996-02-26 2000-05-16 The Procter & Gamble Company Green tea extract subjected to cation exchange treatment and nanofiltration to improve clarity and color
JP3320307B2 (ja) * 1996-06-06 2002-09-03 株式会社エス・ディー・エス バイオテック フェノール性化合物等の高分子化方法及びその利用
US6642277B1 (en) * 1996-09-20 2003-11-04 The Howard Foundation Food supplements containing polyphenols
DE69739394D1 (de) * 1996-10-16 2009-06-18 Napo Pharmaceuticals Inc Enteral-formulierungen von proanthocyanidzusammensetzungen gegen diarrhöe
US6436342B1 (en) * 1996-11-13 2002-08-20 The Procter & Gamble Company Sprayable disinfecting compositions and processes for disinfecting surfaces therewith
WO1998023716A2 (en) * 1996-11-25 1998-06-04 Unilever N.V. Enzymatic oxidation process
US5891440A (en) 1996-12-31 1999-04-06 Lansky; Ephraim Philip Phytoestrogen supplement prepared from pomegranate seeds and a herbal mixture or coconut milk
JPH1143696A (ja) * 1997-07-29 1999-02-16 Saito Shigeru 緑茶入り洗浄料
GB9721139D0 (en) 1997-10-07 1997-12-03 Glaxo Group Ltd Medicaments
JP4137224B2 (ja) * 1998-03-31 2008-08-20 天野エンザイム株式会社 酵素による蛋白質の架橋法
JP4357624B2 (ja) * 1998-04-01 2009-11-04 大正製薬株式会社 殺菌剤および消化酵素を配合した組成物
US6071541A (en) * 1998-07-31 2000-06-06 Murad; Howard Pharmaceutical compositions and methods for managing skin conditions
WO2000020406A1 (en) * 1998-10-06 2000-04-13 Research Development Foundation ANTIBACTERIAL AND ANTIFUNGAL FLAVANONES FROM $i(EYSENHARDTIA TEXANA)
US20030078212A1 (en) 1998-10-30 2003-04-24 Jia-He Li Pharmaceutical compositions containing poly(adp-ribose) glycohydrolase inhibitors and methods of using the same
US6630163B1 (en) * 1999-04-22 2003-10-07 Howard Murad Method of treating dermatological disorders with fruit extracts
US7297344B1 (en) 1999-05-27 2007-11-20 Euro-Celtique, S.A. Preparations for the promotion of wound healing in the upper respiratory tract and/or ear
US7504251B2 (en) * 1999-06-03 2009-03-17 Biobalance Llc Bacterial strain, processed plant extracts, compositions containing same, processes for their preparation and their therapeutic and industrial applications
GB9918028D0 (en) * 1999-07-30 1999-09-29 Unilever Plc Skin care composition
US6716805B1 (en) * 1999-09-27 2004-04-06 The Procter & Gamble Company Hard surface cleaning compositions, premoistened wipes, methods of use, and articles comprising said compositions or wipes and instructions for use resulting in easier cleaning and maintenance, improved surface appearance and/or hygiene under stress conditions such as no-rinse
KR100366608B1 (ko) * 2000-02-15 2003-01-09 마스터진(주) 형질전환 식물체로부터 생산된 재조합 인간 파필로마바이러스 백신
US20020034553A1 (en) * 2000-09-19 2002-03-21 Janice Zayas Skin healing, conditioning and enhancing lotion
ES2275552T3 (es) * 2000-09-29 2007-06-16 THE PROCTER & GAMBLE COMPANY Composiciones de neutralizacion de alergenos.
RU2278709C2 (ru) * 2001-01-16 2006-06-27 Унилевер Н.В. Пероральная композиция
US7381427B2 (en) * 2001-02-09 2008-06-03 Mickey Miller Seborrheic keratosis treatment
JP4382295B2 (ja) * 2001-02-15 2009-12-09 森永乳業株式会社 ウレアーゼ不活性化組成物及び飲食品
US20030044474A1 (en) 2001-08-03 2003-03-06 Shaklee Corporation High molecular weight, lipophilic, orally ingestible bioactive agents in formulations having improved bioavailability
EP1312412B1 (en) * 2001-11-20 2013-03-13 Mitsubishi Gas Chemical Company, Inc. Process for producing hydrogen-containing gas
CA2472183A1 (en) * 2002-02-28 2003-09-04 Unilever Plc Liquid cleaning compositions
US20030228379A1 (en) * 2002-05-28 2003-12-11 Wenyuan Shi Herbs and herbal combinations useful for the treatment of microbial infections
US20040001665A1 (en) 2002-07-01 2004-01-01 Majd Zoorob Optical device
US6911196B2 (en) * 2002-07-31 2005-06-28 Samir I. Hamtini Topical medicament for treating nappy rash
AU2003293082A1 (en) * 2002-11-27 2004-06-23 Tufts University Antioxidant-functionalized polymers
KR100505819B1 (ko) * 2002-12-23 2005-08-03 (주)오비티 식물의 흰가루병 방제제
US20040228831A1 (en) * 2003-05-15 2004-11-18 Belinka Benjamin A. Polymeric conjugates for tissue activated drug delivery
KR20050028755A (ko) * 2003-09-19 2005-03-23 한국염색기술연구소 오배자로부터 천연항균제를 추출하는 방법
WO2005067727A1 (en) * 2004-01-16 2005-07-28 Unilever Plc Process for the manufacture of a tea product and products obtained thereby
ZA200605708B (en) * 2004-01-16 2008-01-30 Unilever Plc Process for the manufacture of a tea product and products obtained thereby
US7744555B2 (en) * 2004-02-06 2010-06-29 Depuy Spine, Inc. Implant having a photocatalytic unit
WO2005087240A1 (ja) 2004-03-16 2005-09-22 Combi Co. 家畜・家禽用下痢抑制剤
KR20070007837A (ko) * 2004-03-23 2007-01-16 라이프라인 뉴트러세티컬스 코포레이션 포유류에서 염증과 산화적 스트레스 완화를 위한 조성물 및방법
AU2005231416A1 (en) * 2004-04-01 2005-10-20 Smithkline Beecham Corporation Dissolvable tooth whitening strip
US20060024385A1 (en) 2004-07-27 2006-02-02 Pedersen Mark A Metabolic capacity enhancing compositions and methods for use in a mammal
US20060024339A1 (en) * 2004-07-29 2006-02-02 Howard Murad Methods of managing the redness associated with a dermatological condition
JP4798973B2 (ja) * 2004-08-04 2011-10-19 丸善製薬株式会社 抗菌用組成物
WO2006038893A1 (en) 2004-10-06 2006-04-13 Agency For Science, Technology And Research Oxidation of phenolic compound with hydrogen peroxide generated in the presence of the phenolic compound
JP2006182727A (ja) * 2004-12-28 2006-07-13 Kao Corp 酸化染毛剤
US20060165812A1 (en) * 2005-01-21 2006-07-27 Amershire Investment Corporation Method and topical formulation for treating headaches
AR057325A1 (es) * 2005-05-25 2007-11-28 Progenics Pharm Inc Sintesis de (s)-n-metilnaltrexona, composiciones farmaceuticas y usos
US20080311139A1 (en) * 2005-05-27 2008-12-18 University Of Central Florida Research Foundation, Inc. Plant Produced Vaccine for Amebiasis
WO2007003068A1 (fr) 2005-06-30 2007-01-11 Hangzhou Lixin Biotechnology Co. Ltd. Additif pour nourriture, procédé de préparation de celui-ci et application de celui-ci
RU2319494C2 (ru) * 2005-11-11 2008-03-20 РАНХЕЛЬ Хосе Анхель ОЛАЛДЕ Синергетическая композиция растительного происхождения (варианты), способ лечения заболеваний с ее использованием
WO2007058935A2 (en) 2005-11-14 2007-05-24 Bausch & Lomb Incorporated Ophthalmic composition for dry eye therapy
US8496914B2 (en) * 2005-12-13 2013-07-30 Richard Paul Bonfiglio Antibacterial oral rinse formulation for preventing coronary artery disease
WO2007092085A2 (en) * 2005-12-20 2007-08-16 Howard Murad Fragranced therapeutic delivery system
WO2007090096A2 (en) * 2006-01-27 2007-08-09 Rdx Technologies, Inc. Electrochemical methods for redox control to preserve, stabilize and activate compounds
WO2007117352A2 (en) * 2006-02-08 2007-10-18 Howard Murad Topical therapeutic delivery system
EP2015639A4 (en) 2006-05-01 2009-11-25 Napo Pharmaceuticals Inc METHOD OF TREATING IRRITABLE COLON SYNDROME WITH PREDOMINANT CONSTIPATION
JP4892727B2 (ja) * 2006-09-21 2012-03-07 国立大学法人 鹿児島大学 高分子タンニンの酵素的架橋反応
CN1939468B (zh) * 2006-09-27 2010-04-14 西南大学 复方五倍子渔用抗菌剂配方
JP2008143808A (ja) * 2006-12-07 2008-06-26 Airomin Seiyaku Kk 高濃度のコロイド状の有機ヨウ素を含有する液体製剤及びその製造方法
WO2008079898A1 (en) * 2006-12-20 2008-07-03 Pharmwest, Inc. Methods and topical formulations comprising colloidal metal for treating or preventing skin conditions
KR100870138B1 (ko) * 2007-05-15 2008-11-24 한국식품연구원 삶은 나물의 신선도 유지를 위한 천연항균제 및 동천연항균제를 포함하는 삶은 나물 용기
PT2187736E (pt) * 2007-08-16 2015-11-03 Univ Chicago Resistência de plantas a agentes patogénicos
CN101260129A (zh) * 2008-04-12 2008-09-10 竹山县天新医药化工有限责任公司 一种单宁酸的提纯方法
WO2010018418A1 (en) 2008-08-12 2010-02-18 Novatech D.O.O. Formulation based on micronized clinoptilolite as therapeutic agent providing highly bioavailable silicon
SG10201502453SA (en) 2009-03-04 2015-05-28 Liveleaf Inc Method and material for site activated complexing of biologic molecules
US8722040B2 (en) * 2011-06-24 2014-05-13 Liveleaf, Inc. Site-activated binding systems that selectively increase the bioactivity of phenolic compounds at target sites
US8716351B1 (en) * 2012-12-23 2014-05-06 Liveleaf, Inc. Methods of treating gastrointestinal spasms

Also Published As

Publication number Publication date
PH12017501978A1 (en) 2019-01-28
ES2791485T3 (es) 2020-11-04
KR101790352B1 (ko) 2017-10-26
MY172676A (en) 2019-12-10
BRPI1006287A2 (pt) 2015-08-25
SG10201502453SA (en) 2015-05-28
MX2011009242A (es) 2012-02-28
JP2017061529A (ja) 2017-03-30
DK2403938T3 (da) 2020-03-16
SG173905A1 (en) 2011-09-29
IL214951A0 (en) 2011-11-30
HRP20200392T1 (hr) 2020-09-04
US8586110B2 (en) 2013-11-19
JP2012519690A (ja) 2012-08-30
US20140072660A1 (en) 2014-03-13
JP2016000743A (ja) 2016-01-07
CA2754226C (en) 2017-02-28
PL2403938T3 (pl) 2020-09-21
RU2571924C2 (ru) 2015-12-27
US8343552B2 (en) 2013-01-01
EP2403938A1 (en) 2012-01-11
TWI632856B (zh) 2018-08-21
US20100158885A1 (en) 2010-06-24
KR20110123791A (ko) 2011-11-15
US20130078322A1 (en) 2013-03-28
US20140072655A1 (en) 2014-03-13
TW201039752A (en) 2010-11-16
TW201634053A (zh) 2016-10-01
EP2403938A4 (en) 2013-10-16
HUE049150T2 (hu) 2021-12-28
CN102421891A (zh) 2012-04-18
AU2010221579B2 (en) 2015-06-11
JP6047207B2 (ja) 2016-12-21
SG10201503255SA (en) 2015-06-29
CN102421891B (zh) 2015-11-25
IL245765A0 (en) 2016-06-30
CA2754226A1 (en) 2010-09-10
US20190000909A1 (en) 2019-01-03
US20210038674A1 (en) 2021-02-11
ZA201106974B (en) 2012-05-30
US20140161902A1 (en) 2014-06-12
PH12015502712A1 (en) 2016-08-15
WO2010101844A1 (en) 2010-09-10
EP2403938B1 (en) 2019-12-11
AU2010221579A1 (en) 2011-09-15
IL214951A (en) 2016-08-31
PH12015502712B1 (en) 2016-08-15
HK1164916A1 (en) 2012-09-28
RU2011138328A (ru) 2013-04-10

Similar Documents

Publication Publication Date Title
PH12017501978A1 (en) Method and material for site activated complexing of biologic molecules
PH12013501799A1 (en) Compositions and methods comprising cellulase variants with reduced affinity to non-cellulosic materials
MX2010008696A (es) Composiciones de proteina estabilizadas.
WO2009111450A3 (en) Metalloproteinase 9 binding proteins
WO2009111508A3 (en) Metalloproteinase 9 and metalloproteinase 2 binding proteins
WO2012045082A3 (en) Engineered nucleic acids and methods of use thereof
WO2010019625A3 (en) Biocomposites and methods of making the same
AU2009257219A8 (en) Programming and reprogramming of cells
GB201020995D0 (en) Biological materials and uses thereof
MX346001B (es) Polipeptidos de eritropoyetina animal modificados y sus usos.
MY159431A (en) Fibrous materials and compositions
WO2012058588A3 (en) Novel egfr-binding molecules and immunoconjugates thereof
WO2009149956A3 (en) Fusion protein and use thereof
MY153054A (en) Bioprocessing
IL195037A (en) Linker proteins that link to hepatocyte growth, methods for their production and use
WO2011044279A3 (en) Microbial systems for producing commodity chemicals
WO2009120374A3 (en) Methods and compositions for nucleic acid sample preparation
IN2012DN01454A (es)
EP2379577A4 (en) COMPOSITIONS AND METHODS FOR CELL REPROGRAMMING WITHOUT GENETIC MODIFICATION
WO2008027527A3 (en) Processes for producing fats or oils and compositions comprising the fats or oils
AU2011278339A8 (en) Polymer composite material with biocide functionality
MX2012002453A (es) Adsorbente de toxinas.
WO2009102859A3 (en) Polypeptides for microbial detection
WO2011081928A3 (en) Compositions and methods for altering cocaine esterase activity
WO2010096754A8 (en) Compositions and methods to prevent and/or treat cancer with pa -card

Legal Events

Date Code Title Description
FG Grant or registration