MX341504B - Indazol-3-carboxamidas y su uso como inhibidores de la trayectoria de señalización de wnt/b-catenina. - Google Patents

Indazol-3-carboxamidas y su uso como inhibidores de la trayectoria de señalización de wnt/b-catenina.

Info

Publication number
MX341504B
MX341504B MX2014003225A MX2014003225A MX341504B MX 341504 B MX341504 B MX 341504B MX 2014003225 A MX2014003225 A MX 2014003225A MX 2014003225 A MX2014003225 A MX 2014003225A MX 341504 B MX341504 B MX 341504B
Authority
MX
Mexico
Prior art keywords
wnt
indazole
carboxamides
signaling pathway
wnt pathway
Prior art date
Application number
MX2014003225A
Other languages
English (en)
Spanish (es)
Other versions
MX2014003225A (es
Inventor
Kumar Kc Sunil
Hood John
Original Assignee
Samumed Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Samumed Llc filed Critical Samumed Llc
Publication of MX2014003225A publication Critical patent/MX2014003225A/es
Publication of MX341504B publication Critical patent/MX341504B/es

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
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    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • A61K31/416—1,2-Diazoles condensed with carbocyclic ring systems, e.g. indazole
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    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
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    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/4545—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring hetero atom, e.g. pipamperone, anabasine
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MX2014003225A 2011-09-14 2012-09-13 Indazol-3-carboxamidas y su uso como inhibidores de la trayectoria de señalización de wnt/b-catenina. MX341504B (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201161534601P 2011-09-14 2011-09-14
US201261624646P 2012-04-16 2012-04-16
PCT/US2012/055172 WO2013040215A1 (en) 2011-09-14 2012-09-13 Indazole-3-carboxamides and their use as wnt/b-catenin signaling pathway inhibitors

Publications (2)

Publication Number Publication Date
MX2014003225A MX2014003225A (es) 2014-10-14
MX341504B true MX341504B (es) 2016-08-19

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Application Number Title Priority Date Filing Date
MX2016010907A MX362494B (es) 2011-09-14 2012-09-13 Indazol-3-carboxamidas y su uso como inhibidores de la trayectoria de señalizacion de wnt/b-catenina.
MX2014003225A MX341504B (es) 2011-09-14 2012-09-13 Indazol-3-carboxamidas y su uso como inhibidores de la trayectoria de señalización de wnt/b-catenina.
MX2019000845A MX390742B (es) 2011-09-14 2012-09-13 Indazol-3-carboxamidas y su uso como inhibidores de la trayectoria de señalizacion de wnt/b-catenina.

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