MX2023003744A - Metodos para producir edulcorantes de alta intensidad. - Google Patents
Metodos para producir edulcorantes de alta intensidad.Info
- Publication number
- MX2023003744A MX2023003744A MX2023003744A MX2023003744A MX2023003744A MX 2023003744 A MX2023003744 A MX 2023003744A MX 2023003744 A MX2023003744 A MX 2023003744A MX 2023003744 A MX2023003744 A MX 2023003744A MX 2023003744 A MX2023003744 A MX 2023003744A
- Authority
- MX
- Mexico
- Prior art keywords
- methods
- high intensity
- making high
- intensity sweeteners
- mogroside compounds
- Prior art date
Links
- 239000008123 high-intensity sweetener Substances 0.000 title 1
- 235000013615 non-nutritive sweetener Nutrition 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 4
- 229930189775 mogroside Natural products 0.000 abstract 4
- 229940125904 compound 1 Drugs 0.000 abstract 2
- 239000000203 mixture Substances 0.000 abstract 2
- -1 Compound 1 Chemical class 0.000 abstract 1
- 108030005251 Cucurbitadienol synthases Proteins 0.000 abstract 1
- 239000013592 cell lysate Substances 0.000 abstract 1
Classifications
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/14—Yeasts or derivatives thereof
- A23L33/145—Extracts
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P33/00—Preparation of steroids
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L2/00—Non-alcoholic beverages; Dry compositions or concentrates therefor; Their preparation
- A23L2/52—Adding ingredients
- A23L2/60—Sweeteners
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L27/00—Spices; Flavouring agents or condiments; Artificial sweetening agents; Table salts; Dietetic salt substitutes; Preparation or treatment thereof
- A23L27/30—Artificial sweetening agents
- A23L27/33—Artificial sweetening agents containing sugars or derivatives
- A23L27/36—Terpene glycosides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J17/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, having an oxygen-containing hetero ring not condensed with the cyclopenta(a)hydrophenanthrene skeleton
- C07J17/005—Glycosides
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/0004—Oxidoreductases (1.)
- C12N9/0012—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7)
- C12N9/0036—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7) acting on NADH or NADPH (1.6)
- C12N9/0038—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7) acting on NADH or NADPH (1.6) with a heme protein as acceptor (1.6.2)
- C12N9/0042—NADPH-cytochrome P450 reductase (1.6.2.4)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/24—Hydrolases (3) acting on glycosyl compounds (3.2)
- C12N9/2402—Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1)
- C12N9/2405—Glucanases
- C12N9/2434—Glucanases acting on beta-1,4-glucosidic bonds
- C12N9/244—Endo-1,3(4)-beta-glucanase (3.2.1.6)
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/90—Isomerases (5.)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P33/00—Preparation of steroids
- C12P33/12—Acting on D ring
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P33/00—Preparation of steroids
- C12P33/20—Preparation of steroids containing heterocyclic rings
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y106/00—Oxidoreductases acting on NADH or NADPH (1.6)
- C12Y106/02—Oxidoreductases acting on NADH or NADPH (1.6) with a heme protein as acceptor (1.6.2)
- C12Y106/02004—NADPH-hemoprotein reductase (1.6.2.4), i.e. NADP-cytochrome P450-reductase
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y302/00—Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2)
- C12Y302/01—Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
- C12Y302/01006—Endo-1,3(4)-beta-glucanase (3.2.1.6)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y504/00—Intramolecular transferases (5.4)
- C12Y504/99—Intramolecular transferases (5.4) transferring other groups (5.4.99)
- C12Y504/99003—2-Acetolactate mutase (5.4.99.3)
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P19/00—Preparation of compounds containing saccharide radicals
- C12P19/18—Preparation of compounds containing saccharide radicals produced by the action of a glycosyl transferase, e.g. alpha-, beta- or gamma-cyclodextrins
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P19/00—Preparation of compounds containing saccharide radicals
- C12P19/44—Preparation of O-glycosides, e.g. glucosides
- C12P19/56—Preparation of O-glycosides, e.g. glucosides having an oxygen atom of the saccharide radical directly bound to a condensed ring system having three or more carbocyclic rings, e.g. daunomycin, adriamycin
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Molecular Biology (AREA)
- Medicinal Chemistry (AREA)
- Biomedical Technology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nutrition Science (AREA)
- Food Science & Technology (AREA)
- Polymers & Plastics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Mycology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Enzymes And Modification Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Seasonings (AREA)
- Steroid Compounds (AREA)
- Peptides Or Proteins (AREA)
Abstract
En la presente se proporcionan la inclusión de métodos para producir compuestos mogrósido, por ejemplo, el compuesto 1, composiciones (por ejemplo, células hospedadoras) para producir los compuestos mogrósido, y los compuestos mogrósido elaborados por los métodos descritos en la presente, y composiciones (por ejemplo, lisados celulares) y células recombinantes que comprenden los compuestos mogrósido (por ejemplo, el compuesto 1). También se proporcionan en la presente cucurbitadienol sintasa novedosas y el uso de las mismas.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201762501018P | 2017-05-03 | 2017-05-03 | |
US201762551750P | 2017-08-29 | 2017-08-29 |
Publications (1)
Publication Number | Publication Date |
---|---|
MX2023003744A true MX2023003744A (es) | 2023-04-24 |
Family
ID=64016614
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2019012940A MX2019012940A (es) | 2017-05-03 | 2018-05-02 | Metodos para producir edulcorantes de alta intensidad. |
MX2023003744A MX2023003744A (es) | 2017-05-03 | 2019-10-30 | Metodos para producir edulcorantes de alta intensidad. |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2019012940A MX2019012940A (es) | 2017-05-03 | 2018-05-02 | Metodos para producir edulcorantes de alta intensidad. |
Country Status (11)
Country | Link |
---|---|
US (2) | US11060124B2 (es) |
EP (1) | EP3615679A4 (es) |
JP (2) | JP7285786B2 (es) |
CN (1) | CN111108213A (es) |
BR (1) | BR112019023104A2 (es) |
MX (2) | MX2019012940A (es) |
PH (1) | PH12019502456A1 (es) |
RU (1) | RU2767792C2 (es) |
SG (1) | SG11201910136RA (es) |
TW (1) | TW201843304A (es) |
WO (1) | WO2018204483A2 (es) |
Families Citing this family (23)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP3368542B1 (en) | 2015-10-29 | 2022-06-22 | Firmenich Incorporated | High intensity sweeteners |
GB201805576D0 (en) * | 2018-04-04 | 2018-05-16 | Optibiotix Ltd | Sweeteners and methods of production thereof |
EP3860363A1 (en) * | 2018-11-07 | 2021-08-11 | Firmenich Incorporated | Methods for making high intensity sweeteners |
US20240218402A1 (en) * | 2018-11-07 | 2024-07-04 | Firmenich Incorporated | Methods for making high intensity sweeteners |
CA3118924A1 (en) * | 2018-11-09 | 2020-05-14 | Ginkgo Bioworks, Inc. | Biosynthesis of mogrosides |
BR112021016964A8 (pt) * | 2019-02-26 | 2021-12-14 | Coca Cola Co | Métodos de biocatálise de mogrosídeo |
EP3947701A1 (en) | 2019-04-02 | 2022-02-09 | Novozymes A/S | Process for producing a fermentation product |
WO2020200916A1 (en) * | 2019-04-04 | 2020-10-08 | Firmenich Sa | Mogroside compounds and uses thereof |
CN110669094B (zh) * | 2019-10-14 | 2021-12-21 | 上海交通大学 | 罗汉果新苷及其制备方法 |
US20220378072A1 (en) * | 2019-10-25 | 2022-12-01 | Ginkgo Bioworks, Inc. | Biosynthesis of mogrosides |
CN110726787B (zh) * | 2019-11-11 | 2022-10-11 | 广西中烟工业有限责任公司 | 一种分析七种罗汉果皂苷的lc-ms/ms负离子模式检测方法 |
CN110669809B (zh) * | 2019-11-12 | 2022-12-23 | 广西师范大学 | 一种酶法制备罗汉果苷iv和苷v的方法 |
CN113106114B (zh) * | 2020-01-13 | 2024-04-12 | 中国科学院分子植物科学卓越创新中心 | 调控里氏木霉蛋白表达效率的因子、调控方法及应用 |
EP4048086A1 (en) * | 2020-03-05 | 2022-08-31 | Firmenich SA | 11-oxo-cucurbitanes and their use as flavor modifiers |
CN115605081A (zh) * | 2020-03-17 | 2023-01-13 | 可口可乐公司(Us) | 新的罗汉果苷生产系统和方法 |
US20230174993A1 (en) * | 2020-05-13 | 2023-06-08 | Ginkgo Bioworks, Inc. | Biosynthesis of mogrosides |
CN112626094A (zh) * | 2021-01-15 | 2021-04-09 | 中国水产科学研究院黄海水产研究所 | 环糊精葡萄糖基转移酶的基因、氨基酸序列和应用 |
CN113429451B (zh) * | 2021-05-31 | 2022-02-08 | 湖南华诚生物资源股份有限公司 | 一种罗汉果酸酰化衍生物及其制备方法 |
WO2023278226A1 (en) * | 2021-06-29 | 2023-01-05 | Firmenich Incorporated | Mogroside compounds and their comestible use |
CN113481275A (zh) * | 2021-07-23 | 2021-10-08 | 湖南华诚生物资源股份有限公司 | 一种酶催化半合成制备罗汉果赛门苷的方法 |
CN113584110A (zh) * | 2021-08-11 | 2021-11-02 | 河北维达康生物科技有限公司 | 一种以罗汉果醇为底物生物合成罗汉果糖苷v的工程菌株的构建及其应用 |
CN114946910A (zh) * | 2022-03-31 | 2022-08-30 | 广西朗盛食品科技有限公司 | 一种低糖红豆蛋黄酥及其制备方法 |
WO2023225459A2 (en) | 2022-05-14 | 2023-11-23 | Novozymes A/S | Compositions and methods for preventing, treating, supressing and/or eliminating phytopathogenic infestations and infections |
Family Cites Families (54)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6468576B1 (en) | 2000-06-23 | 2002-10-22 | Nestec S.A. | Frozen slush liquid concentrate and method of making same |
US7939059B2 (en) | 2001-12-10 | 2011-05-10 | California Institute Of Technology | Method for the generation of antigen-specific lymphocytes |
WO2005041684A2 (en) | 2003-08-06 | 2005-05-12 | Senomyx Inc. | Novel flavors, flavor modifiers, tastants, taste enhancers, umami or sweet tastants, and/or enhancers and use thereof |
WO2006084186A2 (en) | 2005-02-04 | 2006-08-10 | Senomyx, Inc. | Compounds comprising linked hetero aryl moieties and their use as novel umami flavor modifiers, tastants and taste enhancers for comestible compositions |
WO2006102435A2 (en) | 2005-03-22 | 2006-09-28 | Water Sensations, Inc. | Flavoring composition concentrates |
AR055329A1 (es) | 2005-06-15 | 2007-08-15 | Senomyx Inc | Amidas bis-aromaticas y sus usos como modificadores de sabor dulce, saborizantes, y realzadores de sabor |
ES2640453T3 (es) | 2006-04-21 | 2017-11-03 | Senomyx, Inc. | Procesos para preparar composiciones saborizantes sólidas |
WO2007140339A2 (en) | 2006-05-26 | 2007-12-06 | Amyris Biotechnologies, Inc. | Production of isoprenoids |
US8367395B2 (en) | 2006-09-28 | 2013-02-05 | Dsm Ip Assets B.V. | Production of sterols in oleaginous yeast and fungi |
US7928111B2 (en) | 2007-06-08 | 2011-04-19 | Senomyx, Inc. | Compounds including substituted thienopyrimidinone derivatives as ligands for modulating chemosensory receptors |
EP2188300B1 (en) | 2007-08-17 | 2013-01-30 | Givaudan SA | Novel sweetener iso-mogroside v |
WO2009042070A2 (en) | 2007-09-20 | 2009-04-02 | Amyris Biotechnologies, Inc. | Production of isoprenoids |
EP2247196B1 (en) | 2008-02-06 | 2014-11-26 | Senomyx, Inc. | Sweetener compositions and methods of making them |
TWI429404B (zh) | 2008-03-03 | 2014-03-11 | Senomyx Inc | 異山梨醇衍生物及彼等作為風味改良劑、促味劑及促味增強劑之用途 |
US8586733B2 (en) | 2008-07-31 | 2013-11-19 | Senomyx, Inc. | Processes and intermediates for making sweet taste enhancers |
RU2511315C2 (ru) | 2008-07-31 | 2014-04-10 | Синомикс, Инк. | Композиции, содержащие усилители сладкого вкуса, и способы их получения |
US8481286B2 (en) | 2008-08-12 | 2013-07-09 | Allylix, Inc. | Method for production of isoprenoid compounds |
PT2414311T (pt) | 2009-04-02 | 2017-09-08 | Amyris Inc | Métodos de estabilização e hidrogenação para olefinas de derivados microbianos |
ES2464740T3 (es) | 2009-06-01 | 2014-06-03 | Amyris, Inc. | Método para generar un microbio modificado genéticamente |
ES2625154T3 (es) | 2009-11-23 | 2017-07-18 | Nucelis Llc | Métodos y composiciones para producir escualeno empleando levaduras |
US8981081B2 (en) | 2010-03-12 | 2015-03-17 | Purecircle Usa Inc. | High-purity steviol glycosides |
SG10201507846YA (en) | 2010-04-02 | 2015-10-29 | Senomyx Inc | Sweet flavor modifier |
EP2574187B1 (en) | 2010-05-21 | 2019-09-11 | Amyris, Inc. | Squalane and isosqualane compositions and methods for preparing the same |
US9000054B2 (en) | 2010-08-12 | 2015-04-07 | Senomyx, Inc. | Method of improving stability of sweet enhancer and composition containing stabilized sweet enhancer |
MX359640B (es) | 2010-11-05 | 2018-10-04 | Senomyx Inc | Compuestos utiles como moduladores de trpm8. |
US8962698B2 (en) * | 2011-01-28 | 2015-02-24 | Tate & Lyle Ingredients Americas Llc | Rebaudioside-mogroside V blends |
JP5580488B2 (ja) | 2011-02-02 | 2014-08-27 | アミリス, インコーポレイテッド | テルペンシンターゼ変異体を発生させる方法 |
MX336378B (es) | 2011-08-12 | 2016-01-15 | Senomyx Inc | Modificador del sabor dulce. |
MX346459B (es) | 2011-11-09 | 2017-03-22 | Amyris Inc | Produccion de isoprenoides derivados de acetil - coenzima a. |
RU2633644C2 (ru) * | 2011-11-23 | 2017-10-16 | Эвольва Са | Способы ферментативного синтеза могрозидных соединений |
ES2787899T3 (es) | 2011-12-19 | 2020-10-19 | Purecircle Sdn Bhd | Métodos para purificar glucósidos de esteviol |
KR20150041040A (ko) | 2012-08-06 | 2015-04-15 | 세노믹스, 인코포레이티드 | 단맛 향미 개질제 |
CA2880962C (en) | 2012-08-17 | 2019-07-30 | Evolva Sa | Increased production of terpenes and terpenoids |
WO2016050890A2 (en) * | 2014-10-01 | 2016-04-07 | Evolva Sa | Methods and materials for biosynthesis of mogroside compounds |
CA2893462A1 (en) * | 2012-12-04 | 2014-06-12 | Evolva Sa | Methods and materials for biosynthesis of mogroside compounds |
EP2958897B1 (en) | 2013-02-19 | 2019-01-09 | Senomyx, Inc. | Compounds useful as modulators of trpm8 |
JO3155B1 (ar) | 2013-02-19 | 2017-09-20 | Senomyx Inc | معدِّل نكهة حلوة |
BR112015023089A2 (pt) | 2013-03-15 | 2017-11-21 | Amyris Inc | célula hospedeira, método para produzir um isoprenoide, e método para aumentar a produção de acetil-coa ou um composto derivado de acetil-coa |
GB201309077D0 (en) | 2013-03-15 | 2013-07-03 | Tate & Lyle Ingredients | Improved sweetener |
BR112016012682B1 (pt) * | 2013-12-05 | 2021-12-07 | Analyticon Discovery Gmbh | Composto adoçante |
US20180020709A1 (en) | 2014-04-16 | 2018-01-25 | Purecircle Usa Inc. | Rebaudioside m biosynthetic production and recovery methods |
CN103923152B (zh) | 2014-05-08 | 2015-11-04 | 青岛润德生物科技有限公司 | 一种罗汉果甙v的提取方法 |
IL287789B2 (en) | 2014-09-11 | 2024-05-01 | The State Of Israel Ministry Of Agriculture & Rural Development Agricultural Res Organization Aro Vo | Mogroside compounds, methods for their preparation, preparations including them and their uses |
CA2968331C (en) * | 2014-10-17 | 2024-02-06 | Suntory Holdings Limited | Mogrol glycosyltransferase and gene encoding same |
MX2017005931A (es) | 2014-11-07 | 2017-06-30 | Senomyx Inc | Acidos 4-amino-5- (ciclohexiloxi) quinolina-3-carboxilicos sustituidos como modificadores del sabor dulce. |
MX2017010311A (es) | 2015-02-10 | 2017-12-14 | Purecircle Usa Inc | Metodos de produccion y recuperacion de rebaudiosido m biosintetico. |
CN105039274A (zh) | 2015-07-13 | 2015-11-11 | 中国农业科学院蔬菜花卉研究所 | 参与西瓜葫芦素e合成的基因簇及其应用 |
CA2998134A1 (en) | 2015-09-08 | 2017-03-16 | Viewpoint Therapeutics, Inc. | Compounds and formulations for treating ophthalmic diseases |
EP3368542B1 (en) | 2015-10-29 | 2022-06-22 | Firmenich Incorporated | High intensity sweeteners |
US20190116835A1 (en) | 2016-03-28 | 2019-04-25 | The Coca-Cola Company | Sweetness and Taste Improvement of Steviol Glycoside or Mogroside Sweeteners with Flavonids |
WO2017176873A1 (en) | 2016-04-06 | 2017-10-12 | The Coca-Cola Company | Sweetness and taste improvement of steviol glycoside or mogroside sweeteners |
EP3502265B1 (en) | 2016-07-19 | 2020-12-02 | Suntory Holdings Limited | Method for producing mogrol or mogrol glycoside |
CN117752032A (zh) * | 2017-04-25 | 2024-03-26 | 可口可乐公司 | 二氢查耳酮对甜菊醇糖苷和罗汉果苷甜味剂的甜度和味道改善 |
US11248248B2 (en) | 2017-06-15 | 2022-02-15 | Evolva Sa | Production of mogroside compounds in recombinant hosts |
-
2018
- 2018-05-02 SG SG11201910136R patent/SG11201910136RA/en unknown
- 2018-05-02 CN CN201880044909.3A patent/CN111108213A/zh active Pending
- 2018-05-02 MX MX2019012940A patent/MX2019012940A/es unknown
- 2018-05-02 JP JP2019560352A patent/JP7285786B2/ja active Active
- 2018-05-02 US US15/969,616 patent/US11060124B2/en active Active
- 2018-05-02 RU RU2019138986A patent/RU2767792C2/ru active
- 2018-05-02 BR BR112019023104-8A patent/BR112019023104A2/pt unknown
- 2018-05-02 WO PCT/US2018/030627 patent/WO2018204483A2/en active Search and Examination
- 2018-05-02 EP EP18794373.3A patent/EP3615679A4/en active Pending
- 2018-05-03 TW TW107115087A patent/TW201843304A/zh unknown
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2019
- 2019-10-30 MX MX2023003744A patent/MX2023003744A/es unknown
- 2019-10-30 PH PH12019502456A patent/PH12019502456A1/en unknown
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2021
- 2021-06-23 US US17/355,912 patent/US20210324439A1/en active Pending
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2023
- 2023-01-27 JP JP2023011281A patent/JP2023052703A/ja active Pending
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EP3615679A2 (en) | 2020-03-04 |
RU2767792C2 (ru) | 2022-03-21 |
JP2020518264A (ja) | 2020-06-25 |
TW201843304A (zh) | 2018-12-16 |
PH12019502456A1 (en) | 2020-07-20 |
RU2019138986A3 (es) | 2021-06-03 |
MX2019012940A (es) | 2019-12-16 |
US11060124B2 (en) | 2021-07-13 |
BR112019023104A2 (pt) | 2020-11-03 |
RU2019138986A (ru) | 2021-06-03 |
EP3615679A4 (en) | 2021-02-17 |
US20210324439A1 (en) | 2021-10-21 |
US20190071705A1 (en) | 2019-03-07 |
SG11201910136RA (en) | 2019-11-28 |
JP7285786B2 (ja) | 2023-06-02 |
WO2018204483A2 (en) | 2018-11-08 |
JP2023052703A (ja) | 2023-04-11 |
CN111108213A (zh) | 2020-05-05 |
WO2018204483A3 (en) | 2018-12-20 |
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