MX2017005931A - Acidos 4-amino-5- (ciclohexiloxi) quinolina-3-carboxilicos sustituidos como modificadores del sabor dulce. - Google Patents

Acidos 4-amino-5- (ciclohexiloxi) quinolina-3-carboxilicos sustituidos como modificadores del sabor dulce.

Info

Publication number
MX2017005931A
MX2017005931A MX2017005931A MX2017005931A MX2017005931A MX 2017005931 A MX2017005931 A MX 2017005931A MX 2017005931 A MX2017005931 A MX 2017005931A MX 2017005931 A MX2017005931 A MX 2017005931A MX 2017005931 A MX2017005931 A MX 2017005931A
Authority
MX
Mexico
Prior art keywords
cyclohexyloxy
quinoline
amino
substituted
sweet flavor
Prior art date
Application number
MX2017005931A
Other languages
English (en)
Inventor
Hong Zhang
Tachdjian Catherine
Goran Petrovic
Donald Karanewsky
Fotsing Joseph
Servant Guy
VONG Binh
Weylan Ching Brett
LAPERA Stephanie
Clayton Boren Brant
Chen Qing
Original Assignee
Senomyx Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Senomyx Inc filed Critical Senomyx Inc
Publication of MX2017005931A publication Critical patent/MX2017005931A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C07D215/54—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L2/00—Non-alcoholic beverages; Dry compositions or concentrates therefor; Their preparation
    • A23L2/52—Adding ingredients
    • A23L2/56—Flavouring or bittering agents
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L2/00—Non-alcoholic beverages; Dry compositions or concentrates therefor; Their preparation
    • A23L2/52—Adding ingredients
    • A23L2/60—Sweeteners
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L27/00—Spices; Flavouring agents or condiments; Artificial sweetening agents; Table salts; Dietetic salt substitutes; Preparation or treatment thereof
    • A23L27/20—Synthetic spices, flavouring agents or condiments
    • A23L27/205—Heterocyclic compounds
    • A23L27/2054—Heterocyclic compounds having nitrogen as the only hetero atom
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L27/00—Spices; Flavouring agents or condiments; Artificial sweetening agents; Table salts; Dietetic salt substitutes; Preparation or treatment thereof
    • A23L27/88—Taste or flavour enhancing agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nutrition Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Food Science & Technology (AREA)
  • Polymers & Plastics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Seasonings (AREA)

Abstract

Se exponen en la presente compuestos de ácido 4-amino-5-(ciclohexiloxi)quinolina-3-carboxílico que son útiles como modificadores del sabor dulce. También se exponen en la presente composiciones ingeribles que incluyen uno o más de estos compuestos en combinación con un edulcorante natural o artificial.
MX2017005931A 2014-11-07 2015-10-28 Acidos 4-amino-5- (ciclohexiloxi) quinolina-3-carboxilicos sustituidos como modificadores del sabor dulce. MX2017005931A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201462076975P 2014-11-07 2014-11-07
PCT/US2015/057753 WO2016073251A1 (en) 2014-11-07 2015-10-28 Substituted 4-amino-5-(cyclohexyloxy)quinoline-3-carboxylic acids as sweet flavor modifiers

Publications (1)

Publication Number Publication Date
MX2017005931A true MX2017005931A (es) 2017-06-30

Family

ID=55909633

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2017005931A MX2017005931A (es) 2014-11-07 2015-10-28 Acidos 4-amino-5- (ciclohexiloxi) quinolina-3-carboxilicos sustituidos como modificadores del sabor dulce.

Country Status (7)

Country Link
US (1) US11339128B2 (es)
AU (1) AU2015343463A1 (es)
BR (1) BR112017008738B1 (es)
CA (1) CA2963901A1 (es)
MX (1) MX2017005931A (es)
PH (1) PH12017500656A1 (es)
WO (1) WO2016073251A1 (es)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MY190296A (en) 2015-10-29 2022-04-12 Firmenich Incorporated High intensity sweeteners
MX2019012940A (es) 2017-05-03 2019-12-16 Firmenich Incorporated Metodos para producir edulcorantes de alta intensidad.
US11006659B2 (en) 2017-09-26 2021-05-18 King Saud University Fortified date fruit product
JP2020536537A (ja) 2017-10-06 2020-12-17 カーギル インコーポレイテッド 易溶解性ステビオールグリコシド組成物
EP3952667A1 (en) 2019-04-06 2022-02-16 Cargill, Incorporated Sensory modifiers
JP2024503099A (ja) 2021-01-15 2024-01-24 フィルメニッヒ インコーポレイテッド モグロシドを含む甘味料組成物およびその使用
EP4258895A1 (en) 2021-01-15 2023-10-18 Firmenich Incorporated Sweetener compostions comprising siamenoside i and uses thereof
WO2023172415A1 (en) 2022-03-07 2023-09-14 Firmenich Incorporated Sweetener compositions
WO2023169995A1 (en) 2022-03-10 2023-09-14 Firmenich Sa Sweetener compositions
WO2023198436A2 (en) 2022-04-11 2023-10-19 Firmenich Sa Sweetener compositions

Family Cites Families (53)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2030899A1 (de) 1970-06-18 1971-12-23 Schering Ag, 1000 Berlin Und 4619 Bergkamen Chinolincarbonsäurederivate
FR2101004B2 (es) 1970-08-05 1974-02-01 Bellon Labor Sa Roger
JPS5833843B2 (ja) 1974-10-24 1983-07-22 武田薬品工業株式会社 スイサンヨウ ヤクザイ
JPS52142098A (en) 1976-05-20 1977-11-26 Sumitomo Chem Co Ltd 1-fluoroalkyl-491h)-oxo-3-quinolinecarboxylic acid derivatives
DE3111155A1 (de) 1981-03-21 1982-09-30 Troponwerke GmbH & Co KG, 5000 Köln 5,6-dimethyl-pyrrolo (2,3-b)pyridine, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel
EP0096996B1 (en) 1982-06-15 1988-06-22 Mobil Oil Corporation Process for the conversion of alcohols into petrochemicals
US4552883A (en) 1982-06-15 1985-11-12 Ici Americas Inc. Pyrazolo[3,4-b]pyridine carboxylic acid esters and their pharmaceutical use
GB8600651D0 (en) 1986-01-11 1986-02-19 Beecham Group Plc Compounds
US4952584A (en) 1986-01-11 1990-08-28 Beecham Group P.L.C. 9H-pyrido[2,B-8]indole-3-carboxylic acid ester compounds having useful pharmaceutical activity
GB8610981D0 (en) 1986-05-06 1986-06-11 Ici America Inc Quinoline amides
GB8804447D0 (en) 1988-02-25 1988-03-23 Smithkline Beckman Intercredit Compounds
US5240934A (en) 1990-10-19 1993-08-31 Ss Pharmaceutical Co., Ltd. Quinoline derivatives
GB9125485D0 (en) 1991-11-29 1992-01-29 Merck Sharp & Dohme Therapeutic agents
JPH06199855A (ja) 1992-12-31 1994-07-19 Nippon Nohyaku Co Ltd ピラゾロピリジン誘導体及びこれを含有する血小板凝集抑制剤
US5776942A (en) 1994-06-17 1998-07-07 Nippon Zoki Pharmaceutical Co., Ltd. Bronchodilating pyrido 2,3-d!pyrimidine derivatives
US5593997A (en) 1995-05-23 1997-01-14 Pfizer Inc. 4-aminopyrazolo(3-,4-D)pyrimidine and 4-aminopyrazolo-(3,4-D)pyridine tyrosine kinase inhibitors
AR016817A1 (es) 1997-08-14 2001-08-01 Smithkline Beecham Plc Derivados de fenilurea o feniltiourea, procedimiento para su preparacion, coleccion de compuestos, compuestos intermediarios, composicion farmaceutica,metodo de tratamiento y uso de dichos compuestos para la manufactura de un medicamento
DE19738616A1 (de) 1997-09-04 1999-03-11 Clariant Gmbh 4-Hydroxychinolin-3-carbonsäure-Derivate als Lichtschutzmittel
US6077851A (en) 1998-04-27 2000-06-20 Active Biotech Ab Quinoline derivatives
EP1218401B1 (de) 1999-09-22 2004-06-16 Aventis Pharma Deutschland GmbH 4-benzylaminochinoline konjugate mit gallensaeure und ihre heteroanalogen, verfahren zu ihrer herstellung, diese verbindungen enthaltende arzneimittel und deren anwendung
TW201022287A (en) 2001-01-03 2010-06-16 Senomyx Inc T1R taste receptors and genes encoding same
US20050119302A1 (en) 2001-10-30 2005-06-02 Rahme Laurence G. Methods for the prevention or treament of bacterial and fungal infections
EP1451156A4 (en) 2001-11-27 2005-05-25 Merck & Co Inc 4-AMINOQUINOLINE COMPOUNDS
AU2003248921A1 (en) 2002-07-09 2004-01-23 Point Therapeutics, Inc. Boroproline compound combination therapy
US20080026077A1 (en) 2002-11-12 2008-01-31 John Hilfinger Methods and compositions of gene delivery agents for systemic and local therapy
NZ545747A (en) 2003-08-06 2010-06-25 Senomyx Inc T1R hetero-oligomeric taste receptors, cell lines that express said receptors, and taste compounds
EP1720856B1 (en) 2004-02-11 2013-08-14 GlaxoSmithKline LLC Hiv integrase inhibitors
AU2005221208A1 (en) 2004-03-11 2005-09-22 Neurogen Corporation Substituted 5,12-diaza-benzoanthracene analogues
AR049216A1 (es) 2004-06-09 2006-07-05 Avanir Pharmaceuticals Derivados heterociclicos como mediadores del transporte inverso del colesterol para el tratamiento de hiperlipidemia y enfermedades cardiovasculares relacionadas
CN101006076B (zh) 2004-06-24 2010-09-29 沃泰克斯药物股份有限公司 Atp-结合弹夹转运蛋白的调控剂
UY29016A1 (es) 2004-07-20 2006-02-24 Boehringer Ingelheim Int Analogos de dipeptidos inhibidores de la hepatitis c
US20060045953A1 (en) 2004-08-06 2006-03-02 Catherine Tachdjian Aromatic amides and ureas and their uses as sweet and/or umami flavor modifiers, tastants and taste enhancers
GB0425572D0 (en) 2004-11-19 2004-12-22 Glaxo Group Ltd 1,7-Naphthyridines
JP2008524134A (ja) 2004-12-17 2008-07-10 エフ．ホフマン−ラ ロシュ アーゲー Ｇａｂａ−ｂアロステリックエンハンサーとしてのチエノ−ピリジン誘導体
GB0505621D0 (en) 2005-03-18 2005-04-27 Glaxo Group Ltd Novel compounds
US7304074B2 (en) 2005-04-05 2007-12-04 Hoffmann-La Roche Inc. Substituted 1,5-naphthyridine azolinones
BRPI0611521A2 (pt) 2005-05-18 2010-09-14 Wyeth Corp inibidores de 4,6-diamino-[1,7]naftiridina-3-carbonitrila de quìnase tpl2 e métodos de fabricação e uso dos mesmos
CN101258157A (zh) 2005-05-24 2008-09-03 阿斯利康(瑞典)有限公司 具有抗菌活性的氨基哌啶喹啉及其氮杂等构类似物
AR055329A1 (es) 2005-06-15 2007-08-15 Senomyx Inc Amidas bis-aromaticas y sus usos como modificadores de sabor dulce, saborizantes, y realzadores de sabor
EP2007373A4 (en) 2006-03-29 2012-12-19 Foldrx Pharmaceuticals Inc INHIBITION OF ALPHA SYNUCLEINE TOXICITY
DE102006029446A1 (de) 2006-06-21 2007-12-27 Bayer Schering Pharma Ag Neue 3-substituierte-Chinoline als Kinase-Inhibitoren
US7928111B2 (en) 2007-06-08 2011-04-19 Senomyx, Inc. Compounds including substituted thienopyrimidinone derivatives as ligands for modulating chemosensory receptors
US9603848B2 (en) 2007-06-08 2017-03-28 Senomyx, Inc. Modulation of chemosensory receptors and ligands associated therewith
US8076491B2 (en) 2007-08-21 2011-12-13 Senomyx, Inc. Compounds that inhibit (block) bitter taste in composition and use thereof
CA2705820C (en) 2007-11-15 2016-06-07 Clanotech Ab Quinoline derivatives and their use as tyrosine kinase inhibitors
CN104193723B (zh) 2008-02-06 2019-05-31 西诺米克斯公司 增甜剂组合物及其制备方法
WO2011075559A1 (en) 2009-12-18 2011-06-23 Glaxo Wellcome Manufacturing Pte Ltd. Novel compounds
JP5988506B2 (ja) 2010-04-02 2016-09-07 セノミックス インコーポレイテッド 甘味修飾物質
WO2012021837A2 (en) * 2010-08-12 2012-02-16 Senomyx, Inc. Method of improving stability of sweet enhancer and composition containing stabilized sweet enhancer
AU2012295255B2 (en) 2011-08-12 2016-04-21 Senomyx, Inc. Sweet flavor modifier
WO2013158929A1 (en) 2012-04-18 2013-10-24 Nitto Denko Corporation Phosphor ceramics and methods of making the same
WO2013158928A2 (en) * 2012-04-18 2013-10-24 Elcelyx Therapeutics, Inc. Chemosensory receptor ligand-based therapies
US20140272068A1 (en) * 2013-03-14 2014-09-18 Indra Prakash Beverages containing rare sugars

Also Published As

Publication number Publication date
AU2015343463A1 (en) 2017-06-15
PH12017500656A1 (en) 2017-10-02
CA2963901A1 (en) 2016-05-12
US20160185727A1 (en) 2016-06-30
US11339128B2 (en) 2022-05-24
WO2016073251A1 (en) 2016-05-12
BR112017008738A2 (pt) 2017-12-19
BR112017008738B1 (pt) 2021-06-15

Similar Documents

Publication Publication Date Title
PH12017500656A1 (en) Substituted 4-amino-5-(cyclohexyloxy)quinoline-3-carboxylic acids as sweet flavor modifiers
PH12017501956A1 (en) Compositions of obeticholic acid and methods of use
PH12017501033A1 (en) Oral care compositions and methods of use
PH12017501310A1 (en) Oral care compositions and methods of use
EP3261626A4 (en) Methods and compositions relating to biocompatible implants
EP3232817A4 (en) Steviol glycoside compounds, compositions for oral ingestion or use, and method for enhancing steviol glycoside solubility
EA201691911A1 (ru) Быстродействующие композиции инсулина
EP3146039A4 (en) Micronized wharton's jelly
JO3155B1 (ar) معدِّل نكهة حلوة
EP3167049A4 (en) Micronized wharton's jelly
EP3142695A4 (en) Compositions and methods of enhancing immunogenicity of polysaccharide-protein conjugates
EP3452494A4 (en) COMPOSITIONS AND METHODS RELATED TO HIV-1 IMMUNOGENS
MX2017002803A (es) Coronavirus bovino atenuado y vacunas relacionadas.
MX2013002948A (es) Composiciones farmaceuticas y nutraceuticas de acido abscisico.
EP3148500A4 (en) Oral care compositions having improved stability
EP3223809A4 (en) Amino acid compositions for the treatment of symptoms of disease
MX2017016588A (es) Novedosos glucosidos de triterpeno como edulcorantes o potenciador de edulcorante.
MY181656A (en) Glue composition
EP3176173A4 (en) Crystalline free bases of c-met inhibitor or crystalline acid salts thereof, and preparation methods and uses thereof
EP3139741A4 (en) Methods and compositions comprising 10-hydroxy-2-decenoic acid
EP3148517A4 (en) Compositions and methods to promote bone formation
PH12016501326A1 (en) (s)-3'-methyl-abscisic acid and esters thereof
IL258258B (en) Lipoic acid choline ester preparations and methods for producing biocompatible ophthalmic formulations
EP3165599A4 (en) Novel lactic acid bacterium and composition including said lactic acid bacterium
IL259073A (en) History of abscisic acid - converted at the 3' position