BR112015023089A2 - célula hospedeira, método para produzir um isoprenoide, e método para aumentar a produção de acetil-coa ou um composto derivado de acetil-coa - Google Patents

célula hospedeira, método para produzir um isoprenoide, e método para aumentar a produção de acetil-coa ou um composto derivado de acetil-coa

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Publication number
BR112015023089A2
BR112015023089A2 BR112015023089A BR112015023089A BR112015023089A2 BR 112015023089 A2 BR112015023089 A2 BR 112015023089A2 BR 112015023089 A BR112015023089 A BR 112015023089A BR 112015023089 A BR112015023089 A BR 112015023089A BR 112015023089 A2 BR112015023089 A2 BR 112015023089A2
Authority
BR
Brazil
Prior art keywords
acetyl
coa
host cell
isoprenoid
producing
Prior art date
Application number
BR112015023089A
Other languages
English (en)
Inventor
Leon Meadows Adam
Tai Anna
Ening Tsong Annie
Michelle Hawkins Kristy
Barbara Pickens Lauren
Tipawan Mahatdejkul-Meadows Tina
Original Assignee
Amyris Inc
Total Marketing Services
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Amyris Inc, Total Marketing Services filed Critical Amyris Inc
Publication of BR112015023089A2 publication Critical patent/BR112015023089A2/pt

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y401/00—Carbon-carbon lyases (4.1)
    • C12Y401/02—Aldehyde-lyases (4.1.2)
    • C12Y401/02009—Phosphoketolase (4.1.2.9)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/1025—Acyltransferases (2.3)
    • C12N9/1029—Acyltransferases (2.3) transferring groups other than amino-acyl groups (2.3.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/88—Lyases (4.)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P5/00—Preparation of hydrocarbons or halogenated hydrocarbons
    • C12P5/007—Preparation of hydrocarbons or halogenated hydrocarbons containing one or more isoprene units, i.e. terpenes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/40—Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
    • C12P7/54—Acetic acid
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y203/00—Acyltransferases (2.3)
    • C12Y203/01—Acyltransferases (2.3) transferring groups other than amino-acyl groups (2.3.1)
    • C12Y203/01008—Phosphate acetyltransferase (2.3.1.8)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y301/00—Hydrolases acting on ester bonds (3.1)
    • C12Y301/03—Phosphoric monoester hydrolases (3.1.3)
    • C12Y301/03021—Glycerol-1-phosphatase (3.1.3.21)
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02E—REDUCTION OF GREENHOUSE GAS [GHG] EMISSIONS, RELATED TO ENERGY GENERATION, TRANSMISSION OR DISTRIBUTION
    • Y02E50/00—Technologies for the production of fuel of non-fossil origin
    • Y02E50/10—Biofuels, e.g. bio-diesel
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/52—Improvements relating to the production of bulk chemicals using catalysts, e.g. selective catalysts

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Mycology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)

Abstract

1 / 1 resumo “cã‰lula hospedeira, mã‰todo para produzir um isoprenoide, e mã‰todo para aumentar a produã‡ãƒo de acetil-coa ou um composto derivado de acetil-coa” sã£o aqui fornecidas composiã§ãµes e mã©todos para produã§ã£o melhorada de acetil-coa e compostos derivados de acetil-coa em uma cã©lula hospedeira. em algumas modalidades, a cã©lula hospedeira ã© geneticamente modificada para compreender uma sequãªncia de nucleotã­deo heterã³loga que codifica uma fosfocetolase (pk), e um rompimento funcional de uma enzima endã³gena que converte fosfato de acetila para acetato. em algumas modalidades, a cã©lula hospedeira compreende ainda uma sequãªncia de nucleotã­deo heterã³loga que codifica uma fosfotransacetilase (pta). em algumas modalidades, a enzima que converte fosfato de acetila para acetato ã© uma glicerol-1-fosfatase. em algumas modalidades, a glicerol-1-fosfatase ã© gpp1/rhr2. em algumas modalidades, a glicerol-1-fosfatase ã© gpp2/hor2. as composiã§ãµes e mã©todos aqui descritos fornecem uma passagem eficiente para a produã§ã£o heterã³loga de compostos derivados de acetil-coa, incluindo, mas nã£o limitados a isoprenoides, policetã­deos, e ã¡cidos graxos.
BR112015023089A 2013-03-15 2014-03-14 célula hospedeira, método para produzir um isoprenoide, e método para aumentar a produção de acetil-coa ou um composto derivado de acetil-coa BR112015023089A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201361800356P 2013-03-15 2013-03-15
PCT/US2014/028421 WO2014144135A2 (en) 2013-03-15 2014-03-14 Use of phosphoketolase and phosphotransacetylase for production of acetyl-coenzyme a derived compounds

Publications (1)

Publication Number Publication Date
BR112015023089A2 true BR112015023089A2 (pt) 2017-11-21

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BR112015023089A BR112015023089A2 (pt) 2013-03-15 2014-03-14 célula hospedeira, método para produzir um isoprenoide, e método para aumentar a produção de acetil-coa ou um composto derivado de acetil-coa

Country Status (13)

Country Link
US (1) US9410214B2 (pt)
EP (1) EP2971027B1 (pt)
JP (2) JP6595449B2 (pt)
KR (1) KR102159691B1 (pt)
CN (1) CN105189772B (pt)
AU (1) AU2014227811C1 (pt)
BR (1) BR112015023089A2 (pt)
CA (1) CA2903053C (pt)
ES (1) ES2721920T3 (pt)
MX (1) MX364748B (pt)
MY (1) MY171958A (pt)
WO (1) WO2014144135A2 (pt)
ZA (1) ZA201506406B (pt)

Families Citing this family (42)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SG11201401249PA (en) 2011-10-07 2014-05-29 Danisco Us Inc Utilization of phosphoketolase in the production of mevalonate, isoprenoid precursors, and isoprene
WO2014081803A1 (en) 2012-11-20 2014-05-30 Mascoma Corporation An electron consuming ethanol production pathway to displace glycerol formation in s. cerevisiae
US9580758B2 (en) 2013-11-12 2017-02-28 Luc Montagnier System and method for the detection and treatment of infection by a microbial agent associated with HIV infection
EP3967747B1 (en) 2013-12-03 2023-11-08 Genomatica, Inc. Microorganisms and methods for improving product yields on methanol using acetyl-coa synthesis
EP4421181A2 (en) * 2014-09-18 2024-08-28 Genomatica, Inc. Non-natural microbial organisms with improved energetic efficiency
CN104372017B (zh) * 2014-11-05 2017-06-30 中国科学院青岛生物能源与过程研究所 一种提高基因工程菌异戊二烯及其衍生物产量的方法及应用
WO2017051930A1 (en) * 2015-09-25 2017-03-30 Ajinomoto Co., Inc. Method of producing isoprenoid compound
WO2017058175A1 (en) 2015-09-29 2017-04-06 Kimberly-Clark Worldwide, Inc. Synergistic composition for maintenance of healthy balance of microflora
BR112018008710B1 (pt) 2015-10-29 2022-04-12 Firmenich Incorporated Adoçantes de alta intensidade
US10612032B2 (en) 2016-03-24 2020-04-07 The Board Of Trustees Of The Leland Stanford Junior University Inducible production-phase promoters for coordinated heterologous expression in yeast
JPWO2018079619A1 (ja) * 2016-10-28 2019-09-19 積水化学工業株式会社 組換え細胞、並びに、イソプレン又はテルペンの生産方法
CA3042726A1 (en) * 2016-11-16 2018-05-24 The Board Of Trustees Of The Leland Stanford Junior University Systems and methods for identifying and expressing gene clusters
HUE054304T2 (hu) * 2016-12-16 2021-08-30 Danisco Us Inc Bifunkcionális foszfoketoláz-foszfotranszacetiláz fúziós polipeptidek
MX2019008676A (es) 2017-01-25 2019-09-09 Amyris Bio Products Portugal Unipessoal Lda Coproduccion de un sesquiterpeno y un carotenoide.
CN110234325A (zh) 2017-02-28 2019-09-13 金伯利-克拉克环球有限公司 用于维护微生物群落的健康平衡的协同组合物
US20200063166A1 (en) * 2017-03-13 2020-02-27 Dsm Ip Assets B.V. Zinc binuclear cluster transcriptional regulator-deficient strain
JP7285786B2 (ja) 2017-05-03 2023-06-02 フィルメニッヒ インコーポレイテッド 高強度の甘味料の製造方法
EP3665292B1 (en) 2017-08-07 2024-03-06 Total Raffinage Chimie Process for recovering isoprenoids produced by microorganisms
WO2019030007A1 (en) 2017-08-07 2019-02-14 Total Raffinage Chimie PROCESS FOR RECOVERING FERMENTATION PRODUCTS
JP2019041712A (ja) * 2017-09-05 2019-03-22 株式会社デンソー 組み換え体及びスクアレンの製造方法
CA3075528A1 (en) 2017-09-14 2019-03-21 Lifemine Therapeutics, Inc. Human therapeutic targets and modulators thereof
EP3720944A1 (en) 2017-12-07 2020-10-14 Zymergen Inc. Engineered biosynthetic pathways for production of (6e)-8-hydroxygeraniol by fermentation
BR112020012704A8 (pt) 2017-12-21 2022-03-03 Zymergen Inc Nepetalactol oxidorredutases, nepetalactol sintases, e micróbios capazes de produzir nepetalactona
US11447783B2 (en) 2018-03-06 2022-09-20 Danisco Us Inc. Reduction in acetate production by yeast over-expressing PAB1
WO2019173217A1 (en) * 2018-03-06 2019-09-12 Danisco Us Inc Compositions and methods for increasing ethanol production by yeast using gcy1 and dak1
US20210230640A1 (en) 2018-07-12 2021-07-29 Amyris, Inc. Methods for controlling fermentation feed rates
CN111378588A (zh) * 2018-12-29 2020-07-07 中国科学院青岛生物能源与过程研究所 一种转化纤维素水解液合成法尼烯的基因工程菌及其应用
BR112021022110A2 (pt) * 2019-05-08 2022-01-04 Auxolytic Ltd Métodos de seleção auxotrófica
WO2021022097A1 (en) * 2019-08-01 2021-02-04 Danisco Us Inc Over-expression of adh5p for increased ethanol production by yeast
CN110628806B (zh) * 2019-09-23 2021-09-21 华南理工大学 一种高产β-紫罗兰酮基因工程菌及其构建方法和应用
CN111763662B (zh) * 2019-11-29 2023-12-19 上海京新生物医药有限公司 酮还原酶及其在替格瑞洛中间体合成中的应用
CN112342163A (zh) * 2020-11-13 2021-02-09 华中农业大学 一种伯克霍尔德菌及其应用
US11905544B2 (en) 2020-12-17 2024-02-20 Debut Biotechnology, Inc. Dehydratase variants with improved specific activity for the production of pyruvate from glycerate
JP2024501517A (ja) * 2020-12-18 2024-01-12 デビュー バイオテクノロジー， インコーポレイテッド 無細胞化学物質生産のための多用途連続製造プラットフォーム
CN113430215B (zh) * 2021-06-03 2023-04-18 昆明理工大学 乙酰CoA合成酶基因RKACS1及其应用
CN114480158B (zh) * 2021-09-15 2023-02-03 安徽农业大学 一种戊糖片球菌及其在棉酚降解中的应用
WO2023244843A1 (en) 2022-06-16 2023-12-21 Amyris, Inc. HIGH pH METHODS AND COMPOSITIONS FOR CULTURING GENETICALLY MODIFIED HOST CELLS
NL2032683B1 (en) * 2022-07-18 2024-01-26 Sestina Bio Llc Bioproduction of isoprenoids
CN115305226B (zh) * 2022-09-22 2023-06-16 郑州轻工业大学 一株降解烟碱并产氢的抗辐射不动杆菌zj-22及其应用
CN116926092B (zh) * 2022-10-28 2024-04-26 昆明理工大学 一种泛酸激酶基因RkPank及其应用
CN116064266B (zh) * 2022-11-01 2024-06-14 四川大学 盐胁迫抗性增强的重组酿酒酵母菌及其构建方法与应用
WO2024151689A1 (en) 2023-01-10 2024-07-18 Amyris, Inc. Production of canthaxanthin

Family Cites Families (39)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4703009A (en) 1983-03-08 1987-10-27 Merck & Co., Inc. RDNA cloning vector pVE1, deletion and hybrid mutants and recombinant derivatives thereof products and processes
EP0118367B1 (en) 1983-03-08 1989-04-26 Merck & Co. Inc. Recombinant dna cloning vector pve1, deletion and hybrid mutants, and recombinant derivatives thereof, products and processes
US5272065A (en) 1983-10-20 1993-12-21 Research Foundation Of State University Of New York Regulation of gene expression by employing translational inhibition of MRNA utilizing interfering complementary MRNA
IL81892A (en) 1986-03-21 1995-10-31 Lilly Co Eli Recombinant AND molecule containing a sequence encoding O-methyltransfer macrocin
US5672497A (en) 1986-03-21 1997-09-30 Eli Lilly And Company Method for increasing the antibiotic-producing ability of antibiotic-producing microorganisms
US5098837A (en) 1988-06-07 1992-03-24 Eli Lilly And Company Macrolide biosynthetic genes for use in streptomyces and other organisms
US5149638A (en) 1988-09-29 1992-09-22 Eli Lilly And Company Tylosin biosynthetic genes tylA, tylB and tylI
US5252474A (en) 1989-03-31 1993-10-12 Merck & Co., Inc. Cloning genes from Streptomyces avermitilis for avermectin biosynthesis and the methods for their use
WO1993013663A1 (en) 1992-01-17 1993-07-22 Abbott Laboratories Method of directing biosynthesis of specific polyketides
US5824513A (en) 1991-01-17 1998-10-20 Abbott Laboratories Recombinant DNA method for producing erythromycin analogs
US6060234A (en) 1991-01-17 2000-05-09 Abbott Laboratories Polyketide derivatives and recombinant methods for making same
WO1995012661A1 (en) 1993-11-02 1995-05-11 Merck & Co., Inc. Dna encoding triol polyketide synthase
US5716849A (en) 1994-06-08 1998-02-10 Novartis Finance Corporation Genes for the biosynthesis of soraphen
CA2197524A1 (en) 1996-02-22 1997-08-22 Bradley Stuart Dehoff Polyketide synthase genes
CA2197160C (en) 1996-02-22 2007-05-01 Stanley Gene Burgett Platenolide synthase gene
EP0929681B1 (en) 1996-08-20 2006-09-13 Novartis AG Rifamycin biosynthesis gene cluster
AU5430798A (en) * 1996-11-13 1998-06-03 E.I. Du Pont De Nemours And Company Method for the production of glycerol by recombinant organisms
JP2001511349A (ja) 1997-07-25 2001-08-14 ヘキスト・マリオン・ルセル Ｓａｃｃｈａｒｏｐｏｌｙｓｐｏｒａｅｒｙｔｈｒａｅａ及びＳｔｒｅｐｔｏｍｙｃｅｓａｎｔｉｂｉｏｔｉｃｕｓにおける６−デオキシヘキソースの生合成及び移送のための遺伝子
US6090601A (en) 1998-01-23 2000-07-18 Kosan Bioscience Sorangium polyketide synthase
US6143526A (en) 1998-03-09 2000-11-07 Baltz; Richard H. Biosynthetic genes for spinosyn insecticide production
AU762399C (en) 1998-05-28 2004-02-05 Kosan Biosciences, Inc. Recombinant narbonolide polyketide synthase
NZ508326A (en) 1998-06-18 2003-10-31 Novartis Ag A polyketide synthase and non ribosomal peptide synthase genes, isolated from a myxobacterium, necessary for synthesis of epothiones A and B
US6265202B1 (en) 1998-06-26 2001-07-24 Regents Of The University Of Minnesota DNA encoding methymycin and pikromycin
DE69934242T2 (de) 1998-10-02 2007-09-20 Kosan Biosciences, Inc., Hayward Polyketid synthase enzyme und rekombinante dna konstrukte dafür, zur herstellung von mit fk-506 und fk-520 verwandten verbindungen
JP2003512013A (ja) 1998-10-29 2003-04-02 コーサン バイオサイエンシーズ， インコーポレイテッド 組換えオレアンドライドポリケチドシンターゼ
NZ511722A (en) 1998-11-20 2004-05-28 Kosan Biosciences Inc Recombinant methods and materials for producing epothilone and epothilone derivatives
US7192751B2 (en) 2001-12-06 2007-03-20 The Regents Of The University Of California Biosynthesis of amorpha-4,11-diene
US7253001B2 (en) 2002-03-19 2007-08-07 Forskarpatent I Syd Ab Metabolic engineering for improved xylose utilisation of Saccharomyces cerevisiae
WO2009013157A1 (en) 2007-07-23 2009-01-29 Dsm Ip Assets B.V. Butanol production in a eukaryotic cell
BRPI0922187B1 (pt) 2008-11-19 2021-05-04 Amyris, Inc Métodos para gerar um polinucleotídeo e para gerar uma célula hospedeira
JP4760951B2 (ja) 2009-05-08 2011-08-31 トヨタ自動車株式会社 ブタノール生産能を有する組換え微生物及びブタノールの製造方法
BR122019015752B8 (pt) 2009-08-04 2021-03-16 Evogene Ltd método para aumentar a tolerância ao estresse abiótico, o rendimento, a biomassa, taxa de crescimento e/ou vigor de uma planta, e, construto de ácido nucléico isolado
JP5056897B2 (ja) 2010-05-14 2012-10-24 トヨタ自動車株式会社 ２−ブタノールの製造方法及び２−ブタノール生産能を有する組換え微生物
US8871488B2 (en) 2010-06-18 2014-10-28 Butamax Advanced Biofuels Llc Recombinant host cells comprising phosphoketolases
EP2666855B1 (en) * 2011-01-20 2017-11-22 Toyota Jidosha Kabushiki Kaisha Recombinant yeast and method for producing substance using same
AU2012249320A1 (en) * 2011-04-29 2013-11-14 Danisco Us Inc. Recombinant microorganisms for enhanced production of mevalonate, isoprene, and isoprenoids
EP2546336A1 (en) * 2011-07-11 2013-01-16 DSM IP Assets B.V. Yeast strains that consume uronic acids and produce fermentation products such as ethanol
DK2776571T3 (en) 2011-11-09 2017-06-26 Amyris Inc PREPARATION OF ACETYL-COENZYM A-DERIVED ISOPRENOIDS
US9163263B2 (en) 2012-05-02 2015-10-20 The Goodyear Tire & Rubber Company Identification of isoprene synthase variants with improved properties for the production of isoprene

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ES2721920T3 (es) 2019-08-06
WO2014144135A2 (en) 2014-09-18
ZA201506406B (en) 2017-01-25
KR20150132310A (ko) 2015-11-25
CA2903053C (en) 2023-01-17
AU2014227811B2 (en) 2018-03-22
CA2903053A1 (en) 2014-09-18
AU2014227811A1 (en) 2015-09-24
US9410214B2 (en) 2016-08-09
CN105189772B (zh) 2019-09-13
MX364748B (es) 2019-05-06
US20140273144A1 (en) 2014-09-18
KR102159691B1 (ko) 2020-09-24
JP2019213558A (ja) 2019-12-19
MX2015012365A (es) 2016-04-15
EP2971027B1 (en) 2019-01-30
WO2014144135A3 (en) 2014-10-23
AU2014227811C1 (en) 2018-09-27
MY171958A (en) 2019-11-08
JP6595449B2 (ja) 2019-10-23
EP2971027A2 (en) 2016-01-20
JP2016512047A (ja) 2016-04-25
CN105189772A (zh) 2015-12-23

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