MX2021000715A - Composiciones y metodos para tratar trastornos metabolicos. - Google Patents
Composiciones y metodos para tratar trastornos metabolicos.Info
- Publication number
- MX2021000715A MX2021000715A MX2021000715A MX2021000715A MX2021000715A MX 2021000715 A MX2021000715 A MX 2021000715A MX 2021000715 A MX2021000715 A MX 2021000715A MX 2021000715 A MX2021000715 A MX 2021000715A MX 2021000715 A MX2021000715 A MX 2021000715A
- Authority
- MX
- Mexico
- Prior art keywords
- methods
- metabolic disorders
- treating metabolic
- compositions
- biguanide compounds
- Prior art date
Links
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- A—HUMAN NECESSITIES
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- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
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- A61K31/13—Amines
- A61K31/155—Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
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- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
- A61K31/341—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide not condensed with another ring, e.g. ranitidine, furosemide, bufetolol, muscarine
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- C07D317/48—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring
- C07D317/50—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to atoms of the carbocyclic ring
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Abstract
Se proporcionan métodos para mejorar la tolerabilidad gastrointestinal de los compuestos de biguanida y para tratar trastornos metabólicos y/o inducir la pérdida de peso en pacientes que lo necesitan, particularmente en individuos con una contraindicación para el tratamiento con compuestos de biguanida, que comprenden administrar formulaciones de liberación retardada de dichos compuestos de biguanida, que incluyen metformina, dirigidos al intestino delgado.
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US13/547,022 US8796338B2 (en) | 2011-01-07 | 2012-07-11 | Biguanide compositions and methods of treating metabolic disorders |
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