AR091089A1 - Metodos de tratamiento que utilizan un compuesto de biguanida en una formulacion de liberacion demorada - Google Patents
Metodos de tratamiento que utilizan un compuesto de biguanida en una formulacion de liberacion demoradaInfo
- Publication number
- AR091089A1 AR091089A1 ARP130101728A ARP130101728A AR091089A1 AR 091089 A1 AR091089 A1 AR 091089A1 AR P130101728 A ARP130101728 A AR P130101728A AR P130101728 A ARP130101728 A AR P130101728A AR 091089 A1 AR091089 A1 AR 091089A1
- Authority
- AR
- Argentina
- Prior art keywords
- release formulation
- delayed release
- compound
- biguanida
- treatment methods
- Prior art date
Links
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- A61K31/13—Amines
- A61K31/155—Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
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- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
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- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
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- A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
- A61K31/341—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide not condensed with another ring, e.g. ranitidine, furosemide, bufetolol, muscarine
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Abstract
Reivindicación 1: Un método para mejorar la tolerabilidad gastrointestinal de las biguanidas y/o para reducir las complicaciones gastrointestinales resultantes de su administración, caracterizado porque comprende administrarle a un paciente que lo necesita una cantidad eficaz para el uso terapéutico de un compuesto de biguanida en una formulación de liberación demorada. Reivindicación 2: Un método para tratar un trastorno metabólico en un paciente que lo necesita, caracterizado porque comprende administrarle una cantidad eficaz para el uso terapéutico de un compuesto de biguanida en una formulación de liberación demorada, donde dicho paciente presenta una contraindicación para los compuestos de biguanida.
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