EA200400628A1 - Таблетки метформина с контролируемым высвобождением активного компонента - Google Patents

Таблетки метформина с контролируемым высвобождением активного компонента

Info

Publication number
EA200400628A1
EA200400628A1 EA200400628A EA200400628A EA200400628A1 EA 200400628 A1 EA200400628 A1 EA 200400628A1 EA 200400628 A EA200400628 A EA 200400628A EA 200400628 A EA200400628 A EA 200400628A EA 200400628 A1 EA200400628 A1 EA 200400628A1
Authority
EA
Eurasian Patent Office
Prior art keywords
tablets
metformine
active component
controlled delivery
ionic
Prior art date
Application number
EA200400628A
Other languages
English (en)
Inventor
Маниш Чавла
Раджив С. Рагхуванши
Ашок Рампал
Original Assignee
Рэнбакси Лабораториз Лимитед
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Рэнбакси Лабораториз Лимитед filed Critical Рэнбакси Лабораториз Лимитед
Publication of EA200400628A1 publication Critical patent/EA200400628A1/ru

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/155—Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Diabetes (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)

Abstract

Изобретение предлагает таблетки метформина с контролируемым высвобождением активного компонента и способы приготовления таких таблеток использованием комбинации неионных и анионных гидрофильных полимеров, в которых общее содержание гидрофильного полимера составляет по меньшей мере 16 вес.% композиции.Международная заявка была опубликована вместе с отчетом о международном поиске.
EA200400628A 2001-11-06 2002-11-06 Таблетки метформина с контролируемым высвобождением активного компонента EA200400628A1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IN1134DE2001 2001-11-06
PCT/IB2002/004647 WO2003039527A1 (en) 2001-11-06 2002-11-06 Controlled release tablets of metformin

Publications (1)

Publication Number Publication Date
EA200400628A1 true EA200400628A1 (ru) 2004-12-30

Family

ID=11097132

Family Applications (1)

Application Number Title Priority Date Filing Date
EA200400628A EA200400628A1 (ru) 2001-11-06 2002-11-06 Таблетки метформина с контролируемым высвобождением активного компонента

Country Status (9)

Country Link
US (1) US20030104059A1 (ru)
EP (1) EP1465612A1 (ru)
KR (1) KR20050043765A (ru)
CN (1) CN1700910A (ru)
EA (1) EA200400628A1 (ru)
HU (1) HUP0402058A3 (ru)
PL (1) PL369328A1 (ru)
WO (1) WO2003039527A1 (ru)
ZA (1) ZA200403614B (ru)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2002356419A1 (en) 2002-06-17 2003-12-31 Themis Laboratories Private Limited Multilayer tablets containing thiazolidinedione and biguanides and methods for producing them
EP1646374A1 (en) * 2003-06-16 2006-04-19 Ranbaxy Laboratories, Ltd. Extended-release tablets of metformin
WO2005092293A1 (en) * 2004-03-22 2005-10-06 Ranbaxy Laboratories Limited Formulations of metformin
EP1814528A2 (en) * 2004-10-08 2007-08-08 Rubicon Research Private Limited Process for making a highly compressible controlled delivery compositions of metformin
BR112012011274A2 (pt) * 2009-11-13 2016-04-12 Astrazeneca Uk Ltd formulação de metformina de massa reduzida e sua combinação
US11974971B2 (en) 2011-01-07 2024-05-07 Anji Pharmaceuticals Inc. Compositions and methods for treating metabolic disorders
PT2661266T (pt) 2011-01-07 2020-11-30 Anji Pharma Us Llc Terapias com base em ligandos do recetor quimiossensorial
US9572784B2 (en) 2011-01-07 2017-02-21 Elcelyx Therapeutics, Inc. Compositions comprising statins, biguanides and further agents for reducing cardiometabolic risk
US9211263B2 (en) 2012-01-06 2015-12-15 Elcelyx Therapeutics, Inc. Compositions and methods of treating metabolic disorders
US8796338B2 (en) 2011-01-07 2014-08-05 Elcelyx Therapeutics, Inc Biguanide compositions and methods of treating metabolic disorders
US11759441B2 (en) 2011-01-07 2023-09-19 Anji Pharmaceuticals Inc. Biguanide compositions and methods of treating metabolic disorders
US9480663B2 (en) 2011-01-07 2016-11-01 Elcelyx Therapeutics, Inc. Biguanide compositions and methods of treating metabolic disorders
ES2832773T3 (es) 2012-01-06 2021-06-11 Anji Pharma Us Llc Composiciones de biguanida y métodos de tratamiento de trastornos metabólicos
JP6175074B2 (ja) 2012-01-06 2017-08-02 エルセリクス セラピューティクス インコーポレイテッド 代謝障害を治療するための組成物および方法
WO2016042567A1 (en) * 2014-09-16 2016-03-24 Suresh Pareek Extended release formulation of metformin

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4432757A1 (de) * 1994-09-14 1996-03-21 Boehringer Mannheim Gmbh Pharmazeutische Zubereitung enthaltend Metformin und Verfahren zu deren Herstellung
DE69831335T3 (de) * 1997-06-06 2015-01-15 Depomed, Inc. Im magen verweilende orale dosierungsformen von wasserlöslichen arzneistoffen mit kontrollierter freisetzung
JP4523153B2 (ja) * 1998-03-19 2010-08-11 ブリストル−マイヤーズ スクイブ カンパニー 易溶性薬物の二層性放出制御送達システムおよび方法
US6099859A (en) * 1998-03-20 2000-08-08 Andrx Pharmaceuticals, Inc. Controlled release oral tablet having a unitary core
US6117451A (en) * 1998-08-25 2000-09-12 Pharmalogix, Inc. Direct compression metformin hydrochloride tablets
DE69927708T2 (de) * 1998-12-23 2006-07-06 Alza Corp., Mountain View Dosierungsformen, die poröse partikel enthalten
ES2392705T3 (es) * 2000-10-02 2012-12-13 Usv Ltd. Composiciones farmacéuticas de liberación sostenida que contienen metformina y método para su producción

Also Published As

Publication number Publication date
WO2003039527A1 (en) 2003-05-15
CN1700910A (zh) 2005-11-23
HUP0402058A3 (en) 2006-04-28
KR20050043765A (ko) 2005-05-11
HUP0402058A2 (hu) 2005-02-28
EP1465612A1 (en) 2004-10-13
ZA200403614B (en) 2005-01-14
US20030104059A1 (en) 2003-06-05
PL369328A1 (en) 2005-04-18

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