HUP0402058A2 - Szabályozottan szabaddá váló metformin tabletták és eljárás az előállításukra - Google Patents
Szabályozottan szabaddá váló metformin tabletták és eljárás az előállításukraInfo
- Publication number
- HUP0402058A2 HUP0402058A2 HU0402058A HUP0402058A HUP0402058A2 HU P0402058 A2 HUP0402058 A2 HU P0402058A2 HU 0402058 A HU0402058 A HU 0402058A HU P0402058 A HUP0402058 A HU P0402058A HU P0402058 A2 HUP0402058 A2 HU P0402058A2
- Authority
- HU
- Hungary
- Prior art keywords
- metformin
- preparation
- controlled release
- release tablets
- controlled
- Prior art date
Links
- 238000013270 controlled release Methods 0.000 title abstract 2
- XZWYZXLIPXDOLR-UHFFFAOYSA-N metformin Chemical compound CN(C)C(=N)NC(N)=N XZWYZXLIPXDOLR-UHFFFAOYSA-N 0.000 title abstract 2
- 229960003105 metformin Drugs 0.000 title abstract 2
- 238000000034 method Methods 0.000 title abstract 2
- 229920001477 hydrophilic polymer Polymers 0.000 abstract 2
- 125000000129 anionic group Chemical group 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/155—Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Diabetes (AREA)
- Emergency Medicine (AREA)
- Endocrinology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
Abstract
A találmány tárgya szabályozottan szabaddá váló metformin és eljáráselőállítására nem ionos és anionos hidrofil polimerek kombinációjával,miközben a teljes hidrofil polimer koncentráció a kompozíció legalább16 tömeg%-a. Ó
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IN1134DE2001 | 2001-11-06 | ||
PCT/IB2002/004647 WO2003039527A1 (en) | 2001-11-06 | 2002-11-06 | Controlled release tablets of metformin |
Publications (2)
Publication Number | Publication Date |
---|---|
HUP0402058A2 true HUP0402058A2 (hu) | 2005-02-28 |
HUP0402058A3 HUP0402058A3 (en) | 2006-04-28 |
Family
ID=11097132
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HU0402058A HUP0402058A3 (en) | 2001-11-06 | 2002-11-06 | Controlled release tablets of metformin and process for their preparation |
Country Status (9)
Country | Link |
---|---|
US (1) | US20030104059A1 (hu) |
EP (1) | EP1465612A1 (hu) |
KR (1) | KR20050043765A (hu) |
CN (1) | CN1700910A (hu) |
EA (1) | EA200400628A1 (hu) |
HU (1) | HUP0402058A3 (hu) |
PL (1) | PL369328A1 (hu) |
WO (1) | WO2003039527A1 (hu) |
ZA (1) | ZA200403614B (hu) |
Families Citing this family (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2003105809A1 (en) * | 2002-06-17 | 2003-12-24 | Themis Laboratories Private Limited | Multilayer tablets containing thiazolidinedione and biguanides and methods for producing them |
WO2004110422A1 (en) * | 2003-06-16 | 2004-12-23 | Ranbaxy Laboratories Limited | Extended-release tablets of metformin |
WO2005092293A1 (en) * | 2004-03-22 | 2005-10-06 | Ranbaxy Laboratories Limited | Formulations of metformin |
EP1814528A2 (en) * | 2004-10-08 | 2007-08-08 | Rubicon Research Private Limited | Process for making a highly compressible controlled delivery compositions of metformin |
CA2780938A1 (en) * | 2009-11-13 | 2011-05-19 | Bristol-Myers Squibb Company | Reduced mass metformin formulations |
US11759441B2 (en) | 2011-01-07 | 2023-09-19 | Anji Pharmaceuticals Inc. | Biguanide compositions and methods of treating metabolic disorders |
US8796338B2 (en) | 2011-01-07 | 2014-08-05 | Elcelyx Therapeutics, Inc | Biguanide compositions and methods of treating metabolic disorders |
US9480663B2 (en) | 2011-01-07 | 2016-11-01 | Elcelyx Therapeutics, Inc. | Biguanide compositions and methods of treating metabolic disorders |
US9211263B2 (en) | 2012-01-06 | 2015-12-15 | Elcelyx Therapeutics, Inc. | Compositions and methods of treating metabolic disorders |
US9572784B2 (en) | 2011-01-07 | 2017-02-21 | Elcelyx Therapeutics, Inc. | Compositions comprising statins, biguanides and further agents for reducing cardiometabolic risk |
US11974971B2 (en) | 2011-01-07 | 2024-05-07 | Anji Pharmaceuticals Inc. | Compositions and methods for treating metabolic disorders |
SI2661266T1 (sl) | 2011-01-07 | 2021-01-29 | Anji Pharma (Us) Llc | Terapije, na osnovi kemosenzoričnih receptorskih ligandov |
MX2014008190A (es) | 2012-01-06 | 2015-02-04 | Elcelyx Therapeutics Inc | Composiciones de biguanida y métodos para tratar transtornos metabólicos. |
MX2014008189A (es) | 2012-01-06 | 2015-02-12 | Elcelyx Therapeutics Inc | Composiciones y metodos para tratar trastornos metabolicos. |
WO2016042567A1 (en) * | 2014-09-16 | 2016-03-24 | Suresh Pareek | Extended release formulation of metformin |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE4432757A1 (de) * | 1994-09-14 | 1996-03-21 | Boehringer Mannheim Gmbh | Pharmazeutische Zubereitung enthaltend Metformin und Verfahren zu deren Herstellung |
ES2248908T7 (es) * | 1997-06-06 | 2014-11-24 | Depomed, Inc. | Formas de dosificación de fármacos por vía oral y retención gástrica para liberación continuada de fármacos altamente solubles |
AP1224A (en) * | 1998-03-19 | 2003-11-14 | Bristol Myers Squibb Co | Biphasic controlled release delivery system for high solubility pharmaceuticals and method. |
US6099859A (en) * | 1998-03-20 | 2000-08-08 | Andrx Pharmaceuticals, Inc. | Controlled release oral tablet having a unitary core |
US6117451A (en) * | 1998-08-25 | 2000-09-12 | Pharmalogix, Inc. | Direct compression metformin hydrochloride tablets |
CA2355860C (en) * | 1998-12-23 | 2010-03-30 | Alza Corporation | Dosage forms comprising porous particles |
WO2002028181A1 (en) * | 2000-10-02 | 2002-04-11 | Usv Limited | Sustained release pharmaceutical compositions containing metformin and method of its production |
-
2002
- 2002-11-06 CN CNA028264266A patent/CN1700910A/zh active Pending
- 2002-11-06 HU HU0402058A patent/HUP0402058A3/hu unknown
- 2002-11-06 US US10/289,070 patent/US20030104059A1/en not_active Abandoned
- 2002-11-06 WO PCT/IB2002/004647 patent/WO2003039527A1/en not_active Application Discontinuation
- 2002-11-06 PL PL02369328A patent/PL369328A1/xx not_active Application Discontinuation
- 2002-11-06 KR KR1020047006875A patent/KR20050043765A/ko not_active Application Discontinuation
- 2002-11-06 EA EA200400628A patent/EA200400628A1/ru unknown
- 2002-11-06 EP EP02802686A patent/EP1465612A1/en not_active Withdrawn
-
2004
- 2004-05-12 ZA ZA200403614A patent/ZA200403614B/xx unknown
Also Published As
Publication number | Publication date |
---|---|
CN1700910A (zh) | 2005-11-23 |
KR20050043765A (ko) | 2005-05-11 |
EA200400628A1 (ru) | 2004-12-30 |
HUP0402058A3 (en) | 2006-04-28 |
PL369328A1 (en) | 2005-04-18 |
WO2003039527A1 (en) | 2003-05-15 |
EP1465612A1 (en) | 2004-10-13 |
ZA200403614B (en) | 2005-01-14 |
US20030104059A1 (en) | 2003-06-05 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FD9A | Lapse of provisional protection due to non-payment of fees |